Effects of Quenching Methods and Aging Processes on the Crushing Properties and Microstructure of Al–Zn–Mg Alloy Thin-Walled Square Extrusions

Hui Guo,Jin Zhang,Cheng Wang,Yun‑lai Deng 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.8

In this study, the effects of different (online quenching and offline quenching) quenching methods and aging processes (T6and T73) on the crashworthiness and microstructural evolution of three Al–Zn–Mg alloys (G1–G3) were studied by conductingtensile test and axial compression tests at room temperature, combined with optical metallography, electron back scattereddiffraction, and transmission electron microscopy microstructural observations. The obtained results revealed that thecrushing properties of three different Al–Zn–Mg alloys subjected to different quenching methods and aging processes weresignificantly different. Their crushing energy absorption of are ranked as follows: G1 > G3 > G2. The highest total energyabsorption gap (between T6 and T73) is the G1 alloy, and the lowest one is the G3 alloy. The largest total energy absorptiongap between the two quenching methods is the G3 alloy, and the smallest one is the G1 alloy. The G2 alloy with the largesttotal amount of Zn + Mg has the highest number density of matrix precipitates, the largest precipitate gap (between T6 andT73) and the smallest precipitate gap between the two quenching methods. The G3 alloy with the largest Zn/Mg ratio hasthe smallest number density of matrix precipitates, the minimum precipitation gap (between T6 and T73) and the maximumprecipitation gap between the two quenching methods. The G1 alloy with the lowest Zn/Mg ratio has the smallest size ofgrain boundary precipitates and PFZ width, while their largest values are obtained for the G3 alloy with the maximum Zn/Mg ratio. As a crushing resistant structural material, the crushing properties is improved without reducing the strength. Theratio of Zn/Mg should be controlled within the range of 4.57–6.15, while the total amount of Zn + Mg should be controlledwithin the range of 6.18–7.01.

Detection for Tobacco Mosaic Virus and Potato Virus Y by DNA Chips Techniques

Hui Jia,Jin-Zhong Wang,Si-yuan Wen,Sheng-Qi Wang,Jin-Gao Dong,Min-Zhao Zhang 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

Construction enterprise cost management via value chain analysis

Wang Jin-hui,Zhang Min-min 인하대학교 정석물류통상연구원 2009 인하대학교 정석물류통상연구원 학술대회 Vol.2009 No.10

Intense competition, lower tender and bid price, the owner"s nonstandard behaviors etc. have lowered the economic benefit of construction enterprises nowadays. Therefore, construction enterprises have to reinforce cost management and improve competitiveness to survivie and develop. With the overall improvement of level of management of safety, quality and technology of construction industry, cost management has become the most important factor assessing the competitiveness, viability and development potential of construction enterprises. Cost management by value chain anaysis focuses on the essence of cost and provides a new concept for solving problems of cost management of construction enterprises. Value chain of construction industry and internal value chain, longitudinal value chain and transverse value chain of construction enterprises were analyzed by value chain theories and methods and based on the review of the status quo of cost management of construction enterprises in China. Value chain cost management methods were proposed for construction enterprises. Acquirement of cost advantage by value chain analysis and its significance were discussed, which is helpful for construction enterprises to realize strategic cost management and enhance competitiveness.

Heavy concrete shielding properties for carbon therapy

Jin-Long Wang,Jiade J Lu,Da-Jun Ding,Wen-Hua Jiang,Ya-Dong Li,Rui Qiu,Hui Zhang,Xiao-Zhong Wang,Huo-Sheng Ruan,Yan-Bing Teng,Xiao-Guang Wu,Yun Zheng,Zi-Hao Zhao,Kai-Zhong Liao,Huan-Cheng Mai,Xiao-Dong Korean Nuclear Society 2023 Nuclear Engineering and Technology Vol.55 No.6

As medical facilities are usually built at urban areas, special concrete aggregates and evaluation methods are needed to optimize the design of concrete walls by balancing density, thickness, material composition, cost, and other factors. Carbon treatment rooms require a high radiation shielding requirement, as the neutron yield from carbon therapy is much higher than the neutron yield of protons. In this case study, the maximum carbon energy is 430 MeV/u and the maximum current is 0.27 nA from a hybrid particle therapy system. Hospital or facility construction should consider this requirement to design a special heavy concrete. In this work, magnetite is adopted as the major aggregate. Density is determined mainly by the major aggregate content of magnetite, and a heavy concrete test block was constructed for structural tests. The compressive strength is 35.7 MPa. The density ranges from 3.65 g/cm³ to 4.14 g/cm³, and the iron mass content ranges from 53.78% to 60.38% from the 12 cored sample measurements. It was found that there is a linear relationship between density and iron content, and mixing impurities should be the major reason leading to the nonuniform element and density distribution. The effect of this nonuniformity on radiation shielding properties for a carbon treatment room is investigated by three groups of Monte Carlo simulations. Higher density dominates to reduce shielding thickness. However, a higher content of high-Z elements will weaken the shielding strength, especially at a lower dose rate threshold and vice versa. The weakened side effect of a high iron content on the shielding property is obvious at 2.5 µSv=h. Therefore, we should not blindly pursue high Z content in engineering. If the thickness is constrained to 2 m, then the density can be reduced to 3.3 g/cm³, which will save cost by reducing the magnetite composition with 50.44% iron content. If a higher density of 3.9 g/cm³ with 57.65% iron content is selected for construction, then the thickness of the wall can be reduced to 174.2 cm, which will save space for equipment installation.

Ultrasound Targeted Microbubble Destruction for Novel Dual Targeting of HSP72 and HSC70 in Prostate Cancer

Wang, Hang-Hui,Song, Yi-Xin,Bai, Min,Jin, Li-Fang,Gu, Ji-Ying,Su, Yi-Jin,Liu, Long,Jia, Chao,Du, Lian-Fang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

The aim was to determine whether ultrasound targeted microbubble destruction (UTMD) promotes dual targeting of HSP72 and HSC70 for therapy of castration-resistant prostate cancer (CRPC), to improve the specific and efficient delivery of siRNA, to induce tumor cell specific apoptosis, and to find new therapeutic targets specific of CRPC.VCaP cells were transfected with siRNA oligonucleotides. HSP70, HSP90 and cleaved caspase-3 expression were determined by real-time quantitative polymerase chain reaction and Western blotting. Apoptosis and transfection efficiency were assessed by flow cytometry. Cell viability assays were used to evaluate safety. We found HSP72, HSC70 and HSP90 expression to be absent or weak in normal prostate epithelial cells (RWPE-1), but uniformly strong in prostate cancerous cells (VCaP). UTMD combined with dual targeting of HSP72 and HSC70 siRNA improve the efficiency of transfection, cell uptake of siRNA, downregulation of HSP70 and HSP90 expression in VCaP cells at the mRNA and protein level, and induction of extensive tumor-specific apoptosis. Cell counting kit-8 assays showed decreased cellular viability in the HSP72/HSC70-siRNA silenced group. These results suggest that the combination of UTMD with dual targeting HSP70 therapy for PCa may be most efficacious, providng a novel, reliable, non-invasive, safe targeted approach to improve the specific and efficient delivery of siRNA, and achieve maximal effects.

Expression of lipid metabolism genes provides new insights into intramuscular fat deposition in Laiwu pigs

Wang, Hui,Wang, Jin,Yang, Dan-dan,Liu, Zong-li,Zeng, Yong-qing,Chen, Wei Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.3

Objective: The objective of this study was to measure the special expression pattern of lipid metabolism genes and investigate the molecular mechanisms underlying intramuscular fat (IMF) deposition in Longissimus dorsi muscle of Laiwu pigs. Methods: Thirty-six pigs (Laiwu n = 18; Duroc×Landrace×Yorkshire n = 18) were used for the measurement of the backfat thickness, marbling score, IMF content, and expression of lipid metabolism genes. Results: Significant correlations were found between IMF content and the mRNA expression of lipid metabolism genes. Of the 14 fat deposition genes measured, fatty acid synthase (FASN) showed the strongest correlation (r = 0.75, p = 0.001) with IMF content, and of the 6 fat removal genes, carnitine palmitoyl transferase 1B (CPT1B) exhibited the greatest negative correlation (r = -0.66, p = 0.003) with IMF content in Laiwu pig. Multiple regression analysis showed that CPT1B, FASN, solute carrier family 27 member 1 (SLC27A1), and fatty acid binding protein 3 (FABP3) contributed 38% of the prediction value for IMF content in Laiwu pigs. Of these four variables, CPT1B had the greatest contribution to IMF content (14%) followed by FASN (11%), SLC27A1 (9%), and FABP3 (4%). Conclusion: Our results indicate that the combined effects of an upregulation in fat deposition genes and downregulation in fat removal genes promotes IMF deposition in Laiwu pigs.

현학(玄學)사상 방법과 위진시가(魏晉詩歌)의 예술풍모(藝術風貌) : 현언시(玄言詩)의 "담호과미(淡乎寡味)" 문제(問題)와 겸하여

왕금휘(Jin Hui Wang) 퇴계학부산연구원 2007 退溪學論叢 Vol.13 No.-

玄學사상 방법은 魏晉詩歌의 藝術風貌에 비교적 큰 영향을 끼쳤다. "委運自然" 사상은 詩境을 부드럽고淡遠하게 만들었고, 言意之辨, 특히"得意忘象"의 사상 방법은 詩歌意象으로 하여금 아주 많은 槪括的인 의미를 가지게 하였다. 冥觀靜照의 사상 방법은 또 詩歌의 靜態淸趣美와 직접적인 관련성을 가진다. 南朝詩論家들이 玄言詩가"淡乎寡味"하다는 평가에 대해서는 玄言시인들의 창작 추구와 평론가들의 詩學觀두 차원에서 종합적으로 분석되어야할 것이다. Xuanxue has a relatively big impact on the artistic characteristics of the poetry in the Wei and Jin dynasties. The thoughts of integration into the nature forms the peaceful poetic context; the distiguishment of meaning and internal context especially thoughts and methods of getting the meaning and forgetting the image make the poetry image highly generalized; the method of contemplation is directly related to the quiet and fantastic charm of poetry. The comments about the"Danhuguawei"of the poetic critics of Nan dynasty concerned should be comprehensively analyzed from these two aspects which are the writing pursuit of"Xuanyan"poets as well as the poetry concepts of critics.

琴與魏晉南北朝文人的生活及創作

왕금휘 ( Jin Hui Wang ) 세계문학비교학회 ( 구 한국세계문학비교학회 ) 2008 世界文學比較硏究 Vol.23 No.-

Suppression of Cellular Apoptosis Susceptibility (CSE1L) Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells

Zhu, Jin-Hui,Hong, De-Fei,Song, Yong-Mao,Sun, Li-Feng,Wang, Zhi-Fei,Wang, Jian-Wei Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

The cellular apoptosis susceptibility (CSE1L) gene has been demonstrated to regulate multiple cellular mechanisms including the mitotic spindle check point as well as proliferation and apoptosis. However, the importance of CSE1L in human colon cancer is largely unknown. In the present study, we examined expression levels of CSE1L mRNA by semiquantitative RT-PCR. A lentivirus-mediated small interfering RNA (siRNA) was used to knock down CSE1L expression in the human colon cancer cell line RKO. Changes in CSE1L target gene expression were determined by RT-PCR. Cell proliferation was examined by a high content screening assay. In vitro tumorigenesis was measured by colony-formation assay. Cell cycle distribution and apoptosis were detected by flow cytometric analysis. We found CSE1L mRNA to be expressed in human colon cancer cells. Using a lentivirus based RNAi approach, CSE1L expression was significantly inhibited in RKO cells, causing cell cycle arrest in the G2/M and S phases and a delay in cell proliferation, as well as induction of apoptosis and an inhibition of colony growth capacity. Collectively, the results suggest that silencing of CSE1L may be a potential therapeutic approach for colon cancer.

플라즈마 진단 장치 및 진단 방법에 대한 연구

왕태희(Tae-hui Wang),박민상(Min-sang Park),김미진(Mi-jin Kim),유다희(Da-hui Yoo),이호준(Ho-jun Lee) 대한전기학회 2021 대한전기학회 학술대회 논문집 Vol.2021 No.10

본 연구에서 유도결합형 플라즈마 발생 장치를 사용하였으며, Ar gas를 사용하여 플라즈마를 발생시켰다. Langmuir probe, cut-off probe를 이용해 인가 파워 및 압력 변화에 따른 플라즈마 특성을 관찰하였다. 압력이 증가할수록 플라즈마 전위와 전자 온도는 감소하며, 플라즈마의 밀도는 증가함을 알 수 있었다.