Experimental and numerical study on the oblique water-entry impact of a cavitating vehicle with a disk cavitator

Cheng Chen,Xulong Yuan,Xiyan Liu,Jianjun Dang 대한조선학회 2019 International Journal of Naval Architecture and Oc Vol.11 No.1

In this paper, the oblique water-entry impact of a vehicle with a disk cavitator is studied experimentally and numerically. The effectiveness and accuracy of the numerical simulation are verified quantitatively by the experiments in this paper and the data available in the literature. Then, the numerical model is used to simulate the hydrodynamic characteristics and flow patterns of the vehicle under different entry conditions, and the axial force is found to be an important parameter. The influences of entry angle, entry speed and cavitator area on the axial force are studied. The variation law of the force coefficient and the dimensionless penetration distance at the peak of the axial force are revealed. The research conclusions are beneficial to engineering calculations on the impact force of a vehicle with a disk cavitator over a wide range of water-entry parameters.

Complete genome and phylogenetic analysis of bovine papillomavirus type 15 in Southern Xinjiang dairy cow

Jianjun Hu,Wanqi Zhang,Surinder Singh Chauhan,Changqing Shi,Yumeng Song,Yubing Zhao,Zhehong Wang,Long Cheng,Yingyu Zhang 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.6

Background: Bovine papilloma is a neoplastic disease caused by bovine papillomaviruses (BPVs), which were recently divided into 5 genera and at least 24 genotypes. Objectives: The complete genome sequence of BPV type 15 (BPV Aks-02), a novel putative BPV type from skin samples from infected cows in Southern Xinjiang China, was determined by collecting warty lesions, followed by DNA extraction and amplicon sequencing. Methods: DNA was analyzed initially by polymerase chain reaction (PCR) using the degenerate primers FAP59 and FAP64. The complete genome sequences of the BPV Aks-02 were amplified by PCR using the amplification primers and sequencing primers. Sequence analysis and phylogenetic analysis were performed using bio-informatic software. Results: The nucleotide sequence of the L1 open reading frame (ORF) of BPV Aks-02 was 75% identity to the L1 ORF of BPV-9 reference strain from GenBank. The complete genome consisted of 7,189 base pairs (G + C content of 42.50%) that encoded 5 early (E8, E7, E1, E2, and E4) and 2 late (L1 and L2) genes. The E7 protein contained a consensus CX2CX29CX2C zinc-binding domain and a LxCxE motif. Among the different members of this group, the percentages of the complete genome and ORFs (including 5 early and 2 late ORFs) sequence identity of BPV Aks-02 were closer to the genus Xipapillomavirus 1 of the Xipapillomavirus genus. Phylogenetic analysis and sequence similarities based on the L1 ORF of BPV Aks-02 revealed the same cluster. Conclusions: The results suggest that BPV type (BPV Aks-02) clustered with members of the Xipapillomavirus genus as BPV 15 and were closely related to Xipapillomavirus 1.

Amino ionic liquids-modified magnetic core/shell nanocomposite as an efficient adsorbent for dye removal

Jingjing Cheng,Lijuan Shi,Jianjun Lu 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.36 No.-

Amino ionic liquids modified superparamagnetic mesoporous core/shell nanocomposite (Fe3O4@n-SiO2@mSiO2@DHIM-NH2) was synthesized to remove orange II and amaranth from water. Due to themultiple active sites of the introduced ionic liquids, the adsorbent presents superior adsorptionperformance and instantaneous adsorption capacity. The maximum adsorption capacities are reached atpH 2 due to the protonation of amino groups, which are 153.06 and 84.40 mg g 1 for orange II andamaranth, respectively. The good stability, rapid adsorption kinetics, large adsorption capacity, and highseparation efficiency make Fe3O4@nSiO2@mSiO2@DHIM-NH2 an efficient adsorbent for removinganionic contaminant from water.

Chinese Society of Allergy Guidelines for Diagnosis and Treatment of Allergic Rhinitis

Lei Cheng,Jianjun Chen,Qingling Fu,Shaoheng He,Huabin Li,Zheng Liu,Guolin Tan,Zezhang Tao,Dehui Wang,Weiping Wen,Rui Xu,Yu Xu,Qintai Yang,Chonghua Zhang,Gehua Zhang,Ruxin Zhang,Yuan Zhang,Bing Zhou,Do 대한천식알레르기학회 2018 Allergy, Asthma & Immunology Research Vol.10 No.4

Allergic rhinitis (AR) is a global health problem that causes major illnesses and disabilities worldwide. Epidemiologic studies have demonstrated that the prevalence of AR has increased progressively over the last few decades in more developed countries and currently affects up to 40% of the population worldwide. Likewise, a rising trend of AR has also been observed over the last 2-3 decades in developing countries including China, with the prevalence of AR varying widely in these countries. A survey of self-reported AR over a 6-year period in the general Chinese adult population reported that the standardized prevalence of adult AR increased from 11.1% in 2005 to 17.6% in 2011. An increasing number of original articles and imporclinical trials on the epidemiology, pathophysiologic mechanisms, diagnosis, management and comorbidities of AR in Chinese subjects have been published in international peer-reviewed journals over the past 2 decades, and substantially added to our understanding of this disease as a global problem. Although guidelines for the diagnosis and treatment of AR in Chinese subjects have also been published, they have not been translated into English and therefore not generally accessible for reference to non-Chinese speaking international medical communities. Moreover, methods for the diagnosis and treatment of AR in China have not been standardized entirely and some patients are still treated according to regional preferences. Thus, the present guidelines have been developed by the Chinese Society of Allergy to be accessible to both national and international medical communities involved in the management of AR patients. These guidelines have been prepared in line with existing international guidelines to provide evidence-based recommendations for the diagnosis and management of AR in China.

Complete genome and phylogenetic analysis of bovine papillomavirus type 15 in Southern Xinjiang dairy cow

Hu, Jianjun,Zhang, Wanqi,Chauhan, Surinder Singh,Shi, Changqing,Song, Yumeng,Zhao, Yubing,Wang, Zhehong,Cheng, Long,Zhang, Yingyu The Korean Society of Veterinary Science 2020 Journal of Veterinary Science Vol.21 No.2

Background: Bovine papilloma is a neoplastic disease caused by bovine papillomaviruses (BPVs), which were recently divided into 5 genera and at least 24 genotypes. Objectives: The complete genome sequence of BPV type 15 (BPV Aks-02), a novel putative BPV type from skin samples from infected cows in Southern Xinjiang China, was determined by collecting warty lesions, followed by DNA extraction and amplicon sequencing. Methods: DNA was analyzed initially by polymerase chain reaction (PCR) using the degenerate primers FAP59 and FAP64. The complete genome sequences of the BPV Aks-02 were amplified by PCR using the amplification primers and sequencing primers. Sequence analysis and phylogenetic analysis were performed using bio-informatic software. Results: The nucleotide sequence of the L1 open reading frame (ORF) of BPV Aks-02 was 75% identity to the L1 ORF of BPV-9 reference strain from GenBank. The complete genome consisted of 7,189 base pairs (G + C content of 42.50%) that encoded 5 early (E8, E7, E1, E2, and E4) and 2 late (L1 and L2) genes. The E7 protein contained a consensus CX₂CX₂₉CX₂C zinc-binding domain and a LxCxE motif. Among the different members of this group, the percentages of the complete genome and ORFs (including 5 early and 2 late ORFs) sequence identity of BPV Aks-02 were closer to the genus Xipapillomavirus 1 of the Xipapillomavirus genus. Phylogenetic analysis and sequence similarities based on the L1 ORF of BPV Aks-02 revealed the same cluster. Conclusions: The results suggest that BPV type (BPV Aks-02) clustered with members of the Xipapillomavirus genus as BPV 15 and were closely related to Xipapillomavirus 1.

Experimental and numerical study on the oblique water-entry impact of a cavitating vehicle with a disk cavitator

Chen, Cheng,Yuan, Xulong,Liu, Xiyan,Dang, Jianjun The Society of Naval Architects of Korea 2019 International Journal of Naval Architecture and Oc Vol.11 No.1

In this paper, the oblique water-entry impact of a vehicle with a disk cavitator is studied experimentally and numerically. The effectiveness and accuracy of the numerical simulation are verified quantitatively by the experiments in this paper and the data available in the literature. Then, the numerical model is used to simulate the hydrodynamic characteristics and flow patterns of the vehicle under different entry conditions, and the axial force is found to be an important parameter. The influences of entry angle, entry speed and cavitator area on the axial force are studied. The variation law of the force coefficient and the dimensionless penetration distance at the peak of the axial force are revealed. The research conclusions are beneficial to engineering calculations on the impact force of a vehicle with a disk cavitator over a wide range of water-entry parameters.

Chinese Society of Allergy and Chinese Society of Otorhinolaryngology-Head and Neck Surgery Guideline for Chronic Rhinosinusitis

Zheng Liu,Jianjun Chen,Lei Cheng,Huabin Li,Shixi Liu,Hongfei Lou,Jianbo Shi,Ying Sun,Dehui Wang,Chengshuo Wang,Xiangdong Wang,Yongxiang Wei,Weiping Wen,Pingchang Yang,Qintai Yang,Gehua Zhang,Yuan Zhan 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.2

The current document is based on a consensus reached by a panel of experts from the Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck Surgery, Rhinology Group. Chronic rhinosinusitis (CRS) affects approximately 8% of Chinese adults. The inflammatory and remodeling mechanisms of CRS in the Chinese population differ from those observed in the populations of European descent. Recently, precision medicine has been used to treat inflammation by targeting key biomarkers that are involved in the process. However, there are no CRS guidelines or a consensus available from China that can be shared with the international academia. The guidelines presented in this paper cover the epidemiology, economic burden, genetics and epigenetics, mechanisms, phenotypes and endotypes, diagnosis and differential diagnosis, management, and the current status of CRS in China. These guidelines—with a focus on China—will improve the abilities of clinical and medical staff during the treatment of CRS. Additionally, they will help international agencies in improving the verification of CRS endotypes, mapping of eosinophilic shifts, the identification of suitable biomarkers for endotyping, and predicting responses to therapies. In conclusion, these guidelines will help select therapies, such as pharmacotherapy, surgical approaches and innovative biotherapeutics, which are tailored to each of the individual CRS endotypes.

In SR-GIXRD Study of Oxide Film Evaluation on AISI 304 Stainless Steel in High Temperature Water

Yan Zhao,Jianjun Guan,Feng Liu,Ping Liang,Congqian Cheng,Jie Zhao 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.5

Oxide films on AISI 304 stainless steel in high temperature and high pressure water were detected by a new method thatsynchrotron radiation grazing incidence X-ray diffraction. The morphology, phase structure, thickness and electrochemicalcorrosion resistance of the oxide films were illustrated. A empirical equation for oxide growth is applied to evaluate thechanges in film thickness. Observations suggest that small irregular granular (Fe, Cr)2O3 oxides and polyhedral block (Fe,Cr)3O4 oxides are grown on stainless steel surface. The fine inner (Fe, Cr)2O3 particles preferentially form, and the part isprecipitated by the (Fe, Cr)3O4 structure for the diffusion outward, leading to the formation of external coarse grain oxides. The average size of (Fe, Cr)2O3 is slightly oscillated with the oxidation time, and that of (Fe, Cr)3O4 oxides increases withthe increasing exposure time. The oxide film thickness is less than 500 nm for 24 h oxidation in high temperature water, andfor 240 h oxidation the thickness is less than 800 nm. Polarization and EIS test results indicate that the oxide films of (Fe,Cr)2O3 and (Fe, Cr)3O4 provides corrosion resistance for stainless steel.

Hydrogen sulfide restores cardioprotective effects of remote ischemic preconditioning in aged rats via HIF-1α/Nrf2 signaling pathway

Wang, Haixia,Shi, Xin,Cheng, Longlong,Han, Jie,Mu, Jianjun The Korean Society of Pharmacology 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.3

The present study explored the therapeutic potential of hydrogen sulfide (H2S) in restoring aging-induced loss of cardioprotective effect of remote ischemic preconditioning (RIPC) along with the involvement of signaling pathways. The left hind limb was subjected to four short cycles of ischemia and reperfusion (IR) in young and aged male rats to induce RIPC. The hearts were subjected to IR injury on the Langendorff apparatus after 24 h of RIPC. The measurement of lactate dehydrogenase, creatine kinase and cardiac troponin served to assess the myocardial injury. The levels of H2S, cystathionine β-synthase (CBS), cystathionine γ-lyase (CSE), nuclear factor erythroid 2-related factor 2 (Nrf2), and hypoxia-inducible factor (HIF-1α) were also measured. There was a decrease in cardioprotection in RIPC-subjected old rats in comparison to young rats along with a reduction in the myocardial levels of H2S, CBS, CSE, HIF-1α, and nuclear: cytoplasmic Nrf2 ratio. Supplementation with sodium hydrogen sulfide (NaHS, an H2S donor) and l-cysteine (H2S precursor) restored the cardioprotective actions of RIPC in old hearts. It increased the levels of H2S, HIF-1α, and Nrf2 ratio without affecting CBS and CSE. YC-1 (HIF-1α antagonist) abolished the effects of NaHS and l-cysteine in RIPC-subjected old rats by decreasing the Nrf2 ratio and HIF-1α levels, without altering H2S. The late phase of cardioprotection of RIPC involves an increase in the activity of H2S biosynthetic enzymes, which increases the levels of H2S to upregulate HIF-1α and Nrf2. H2S has the potential to restore aging-induced loss of cardioprotective effects of RIPC by upregulating HIF-1α/Nrf2 signaling.

Seismic Performance of Desert-sand Autoclaved Aerated Concrete Block Wall Constrained by Precast Integral Construction Column

Yushan Wang,Wenxing Zhu,Jianjun Cheng 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.9

Considering the structural types and construction techniques used in common residential buildings in Xinjiang, the paper proposes a novel masonry structure, i.e., desert-sand AAC blocks constrained by a precast integral construction column. In order to study the seismic performance of the structure, five wall specimens with different constraints are designed and fabricated and further compared and analyzed in terms of failure mode, hysteretic performance, energy dissipation capacity, ductility, stiffness degradation, and other performance indexes. It has been determined from the results that under horizontal low-cycle repeated loading, the main failure cracks of the desert-sand AAC block wall constrained by the precast integral construction column are intersecting oblique cracks, and the cracks in wall failure penetrate along concrete blocks. The stiffness degradation rate of the wall constrained by the water-resistant gypsum construction column gradually decreases with increasing vertical compressive stress. The wall constrained by the water-resistant gypsum construction column with arranged steel bars has a desirable ductility. Under the same vertical compressive stress, the wall constrained by the water-resistant gypsum precast construction column with arranged steel bars has a significant energy dissipation capacity from cracking to the ultimate state. (4) A restoring force model is built for desert-sand AAC block walls constrained by the precast integral construction column using a three-fold line model, offering technical support for the elastoplastic seismic analysis of structures.