http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Zheng Liu (검색결과 787 건)
- 무료
- 기관 내 무료
- 유료
-
Research on profile inversion pattern of polymer flooding
Ailing Zheng,Qianghan Feng,Qiansheng Wei,Dehua Liu 한국자원공학회 2018 Geosystem engineering Vol.21 No.3
Polymer flooding is becoming more common and more successful, and has made a great contribution to EOR. However, the statistical analysis of water injection profile data shows that the injection profile easily inverses during the process of single slug polymer flooding in heterogeneous reservoir. It is unfavorable for enhancing oil recovery. According to seepage mechanics theory, the cognition is determined that the injection rate distribution in high and low permeability layers depends on reservoir heterogeneity and physicochemical property of polymer. The basic reason of profile inversion lies in the different dynamic variation of resistance factors in the high and low permeability layers. In order to use existing reservoir simulation software to accurately describe the profile inversion characteristics, a processing method is submitted which is that different polymer characteristic parameters and relative permeability curves are assigned to different regions according to the distributions of reservoir characteristics during polymer flooding. Then, this processing method is used for systematically studying the profile inversion laws of different permeability ratio, polymer concentration and injecting-polymer occasion. The results show that these factors have great influence on the profile inversion. This provides a technical support for studying the profile inversion rules and corresponding improvement method.
-
Zheng Yuchen,Hayashi Fumio,Matsumoto Rikio,Liu Xingyue 한국응용곤충학회 2024 Journal of Asia-Pacific Entomology Vol.27 No.1
An antlion species-group of Dendroleon Brauer, 1866, namely the D. pupillaris group, is defined, including five species (two described species and three new species): D. jianyuni Zheng & Liu sp. nov., D. motuoensis Wang & Wang, 2008, D. pupillaris (Gerstaecker, 1893), D. wenii Zheng, Hayashi, Matsumoto & Liu sp. nov., and D. xiaohani Zheng & Liu sp. nov. We sequenced the DNA barcodes of all species to test our morphological species delimitation. The immature stage of D. jianyuni sp. nov. is also described. In addition, the generic diagnosis of Dendroleon is further discussed. https://www.zoobank.org/zoobank.org:pub:91282009-E5D4-41EB-BCD5-2B96AA4D6516.
-
Liu Liu SHI,Ying Zheng LIU,Jin Jin WAN 대한기계학회 2010 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.24 No.1
The separated and reattaching turbulent flow over a surface-mounted two-dimensional square cylinder was experimentally studied by using time-resolved particle image velocimetry (TR-PIV). A total of 61,440 instantaneous image frames were acquired at a framing rate of 125 Hz, yielding a reliable result of the statistical quantities. The time-averaged features of the separated and reattaching flow were analyzed in terms of distributions of the velocity vectors, vorticity, the streamwise velocity fluctuation intensity and shear stress. The association between the large-scale vortical structures and spatial variation of these time-averaged quantities were thoroughly discussed. The unsteady features of the flow were revealed from distributions of the reverse-flow intermittency, space-time contour plot of the fluctuating streamwise velocity, and cross-correlation of the streamwise velocity. Subsequently, a comprehensive understanding of the contribution of the flow structures into the fluctuating flow field was gained by using a snapshot proper orthogonal decomposition (POD)analysis. The results showed that the linear combination of the first five POD modes, which capture 57% of the fluctuation energy, was capable of representing the large-scale behaviors of the separated and reattaching turbulent flow in the senses of spectrum, instantaneous feature and spatial variation of the velocity fluctuation intensity.
-
Yufeng Zheng(Yufeng Zheng),Xue Liu(Xue Liu),Na Li(Na Li),Aimei Zhao(Aimei Zhao),Zhiqiang Sun(Zhiqiang Sun),Meihua Wang(Meihua Wang),Judong Luo(Judong Luo) 대한방사선종양학회 2023 Radiation Oncology Journal Vol.41 No.2
Purpose: To analyze the gene mutation, immune infiltration and tumor growth of primary tumor and distant tumor under different treatment modes. Materials and Methods: Twenty B16 murine melanoma cells were injected subcutaneously into the of both sides of the thigh, simulating a primary tumor and a secondary tumor impacted by the abscopal effect, respectively. They were divided into blank control group, immunotherapy group, radiotherapy group, and radiotherapy combined immunotherapy group. During this period, tumor volume was measured, and RNA sequencing was performed on tumor samples after the test. R software was used to analyze differentially expressed genes, functional enrichment, and immune infiltration. Results: We found that any treatment mode could cause changes in differentially expressed genes, especially the combination treatment. The different therapeutic effects might be caused by gene expression. In addition, the proportions of infiltrating immune cells in the irradiated and abscopal tumors were different. In the combination treatment group, T-cell infiltration in the irradiated site was the most obvious. In the immunotherapy group, CD8+ T-cell infiltration in the abscopal tumor site was obvious, but immunotherapy alone might have a poor prognosis. Whether the irradiated or abscopal tumor was evaluated, radiotherapy combined with anti-programmed cell death protein 1 (anti-PD-1) therapy produced the most obvious tumor control and might have a positive impact on prognosis. Conclusion: Combination therapy not only improves the immune microenvironment but may also have a positive impact on prognosis.
-
Zheng Liu,Jianjun Chen,Lei Cheng,Huabin Li,Shixi Liu,Hongfei Lou,Jianbo Shi,Ying Sun,Dehui Wang,Chengshuo Wang,Xiangdong Wang,Yongxiang Wei,Weiping Wen,Pingchang Yang,Qintai Yang,Gehua Zhang,Yuan Zhan 대한천식알레르기학회 2020 Allergy, Asthma & Immunology Research Vol.12 No.2
The current document is based on a consensus reached by a panel of experts from the Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck Surgery, Rhinology Group. Chronic rhinosinusitis (CRS) affects approximately 8% of Chinese adults. The inflammatory and remodeling mechanisms of CRS in the Chinese population differ from those observed in the populations of European descent. Recently, precision medicine has been used to treat inflammation by targeting key biomarkers that are involved in the process. However, there are no CRS guidelines or a consensus available from China that can be shared with the international academia. The guidelines presented in this paper cover the epidemiology, economic burden, genetics and epigenetics, mechanisms, phenotypes and endotypes, diagnosis and differential diagnosis, management, and the current status of CRS in China. These guidelines—with a focus on China—will improve the abilities of clinical and medical staff during the treatment of CRS. Additionally, they will help international agencies in improving the verification of CRS endotypes, mapping of eosinophilic shifts, the identification of suitable biomarkers for endotyping, and predicting responses to therapies. In conclusion, these guidelines will help select therapies, such as pharmacotherapy, surgical approaches and innovative biotherapeutics, which are tailored to each of the individual CRS endotypes.
-
Liu, Yi-Qing,Zhang, Guo-An,Zhang, Bing-Chang,Wang, Yong,Liu, Zheng,Jiao, Yu-Lian,Liu, Ning,Zhao, Yue-Ran Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.3
Background: Prostate cancer is one of the main causes of cancer death, and drug resistance is the leading reason for therapy failure. However, how this occurs is largely unknown. We therrfore aimed to study the response of DU145 cells to cisplatin. Materials and Methods: Du145 prostate cancer cells were treated with a low dose of cisplatin for 24 h and cell viability and number were determined by MTT assay and trypan blue exclusion assay, respectively. The real time polymerase chain reaction (PCR) was used to assess responses to cisplatin treatment. Results: After 24h $2{\mu}g/ml$ treatment did not result in significant reduction in cell viability or number. However, it led to enhanced cancer cell invasiveness. E-cadherin mRNA was reduced, and vimentin, Snail, Slug, metalloproteinase 9 (MMP9) mRNA expression increased significantly, a feature of epithelial-mesenchymal transition (EMT). Conclusions: Short time low concentration cisplatin treatment leads to elevated invasiveness of DU145 cancer cells and this is possibly due to EMT.
-
Liu, Qian,Bi, Jian-Jun,Tian, Yan-Tao,Feng, Qiang,Zheng, Zhao-Xu,Wang, Zheng Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4
Background: The optimal surgical strategy for the treatment of synchronous resectable gastric cancer liver metastases remains controversial. The aims of this study were to analyze the outcome and overall survival of patients presenting with gastric cancer and liver metastases treated by simultaneous resection. Materials and Methods: Between January 1990 and June 2009, 35 patients diagnosed with synchronous hepatic metastases from gastric carcinoma received simultaneous resection of both primary gastric cancer and synchronous hepatic metastases. The clinicopathologic features and the surgical results of the 35 patients were retrospectively analyzed. Results: The 5-year overall survival rate after surgery was 14.3%. Five patients survived for more than 5 years after surgery. No mortality has occurred within 30 days after resection, although two patients (5.7%) developed complications during the peri-operative course. Univariate analysis revealed that patients with the presence of lymphovascular invasion of the primary tumor, bilateral liver metastasis and multiple liver metastases suffered poor survival. Lymphovascular invasion by the primary lesion and multiple liver metastases were significant prognostic factors that influenced survival in the multivariate analysis (p=0.02, p=0.001, respectively). Conclusions: The presence of lymphovascular invasion of the primary tumor and multiple liver metastases are significant prognostic determinants of survival. Gastric cancer patients without lymphovascular invasion and with a solitary synchronous liver metastasis may be good candidates for hepatic resection. Simultaneous resection of both primary gastric cancer and synchronous hepatic metastases may effectively prolong survival in strictly selected patients.
-
Liu, Shu-Zheng,Wang, Bing,Zhang, Fang,Chen, Qiong,Yu, Liang,Cheng, Lan-Ping,Sun, Xi-Bin,Duan, Guang-Cai Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10
This study describes recent trends in incidence, survival and prevalence of subgroups of esophageal and gastric cancer in Linzhou city between 2003 and 2009. Data of esophageal and gastric cancer for the period of interest were extracted from the Linzhou Cancer Registry. Using information on tumor morphology or anatomical site, data were divided into six groups; esophageal squamous cell carcinoma, esophageal adenocarcinoma, other and unspecified types of esophageal cancer, and cardia, non-cardia, and unspecified anatomical site of stomach cancer. Incidence, survival and prevalence rates for each of the six cancer groups were calculated. The majority of esophageal cancers were squamous cell carcinomas (82%). Cardiac cancer was the major gastric cancer group (64%). The incidence of esophageal squamous cell carcinoma and gastric cardiac cancer increased between 2003 and 2009. Both esophageal and gastric cancer had a higher incidence in males compared with females. Overall survival was poor in all sub-groups with 1 year survival ranging from 45.9 to 65.6% and 5 year survival ranging from 14.7 to 30.5%. Prevalence of esophageal squamous cell carcinoma and gastric cardiac cancer was high (accounting for 80% overall). An increased focus on prevention and early diagnosis, especially in esophageal squamous cell carcinoma and gastric cardiac cancer, is required.
-
Zheng-Wei Chen,Syeda Anam Hashmi,Tanghong Liu,Wenhui Li,Zhuang Sun,Dongrun Liu,Hassan Hemida,Hong-Kang Liu 한국풍공학회 2022 Wind and Structures, An International Journal (WAS Vol.35 No.5
Due to the complex terrain around high-speed railways, the windbreaks were established along different landforms, resulting in irregular windbreak transition regions between different subgrade infrastructures (flat ground, cutting, embankment, etc). In this paper, the effect of a windbreak transition on the wind flow around railways subjected to crosswinds was studied. Wind tunnel testing was conducted to study the wind speed change around a windbreak transition on flat ground with a uniform wind speed inflow, and the collected data were used to validate a numerical simulation based on a detached eddy simulation method. The validated numerical method was then used to investigate the effect of the windbreak transition from the flat ground to cutting (the “cutting” is a railway subgrade type formed by digging down from the original ground) for three different wind incidence angles of 90º, 75º, and 105º. The deterioration mechanism of the flow fields and the reasons behind the occurrence of the peak wind velocities were explained in detail. The results showed that for the windbreak transition on flat ground, the impact was small. For the transition from the flat ground to the cutting, the influence was relatively large. The significant increase in the wind speeds was due to the right-angle structure of the windbreak transition, which resulted in sudden changes of the wind velocity as well as the direction. In addition, the height mismatch in the transition region worsened the protective effect of a typical windbreak.
-
A miR-155–Peli1–c-Rel pathway controls the generation and function of T follicular helper cells
Liu, Wen-Hsien,Kang, Seung Goo,Huang, Zhe,Wu, Cheng-Jang,Jin, Hyun Yong,Maine, Christian J.,Liu, Yi,Shepherd, Jovan,Sabouri-Ghomi, Mohsen,Gonzalez-Martin, Alicia,Xu, Shunbin,Hoffmann, Alexander,Zheng, The Rockefeller University Press 2016 The Journal of experimental medicine Vol.213 No.9
<P>MicroRNA (miRNA) deficiency impairs the generation of T follicular helper (Tfh) cells, but the contribution of individual miRNAs to this phenotype remains poorly understood. In this study, we performed deep sequencing analysis of miRNAs expressed in Tfh cells and identified a five-miRNA signature. Analyses of mutant mice deficient of these miRNAs revealed that miR-22 and miR-183/96/182 are dispensable, but miR-155 is essential for the generation and function of Tfh cells. miR-155 deficiency led to decreased proliferation specifically at the late stage of Tfh cell differentiation and reduced CD40 ligand (CD40L) expression on antigen-specific CD4<SUP>+</SUP> T cells. Mechanistically, miR-155 repressed the expression of Peli1, a ubiquitin ligase that promotes the degradation of the NF-κB family transcription factor c-Rel, which controls cellular proliferation and CD40L expression. Therefore, our study identifies a novel miR-155–Peli1–c-Rel pathway that specifically regulates Tfh cell generation and function.</P>
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
