한국에서의 Human T-Cell Leukemia Virus Type-1(HTLV-1)에 대한 혈청학적 및 역학에 관한 연구

이영열,이성열,김은실,이홍복,김병국,이문호,박선양,김노경,서철원,규경채,최강원,조한익,고월청,야마구찌이찌세이 대한내과학회 1986 대한내과학회지 Vol.31 No.2

Type-C retrovirus, human T-cell leukemia virus type-l(HTLV-1), has been shown to be associated etiologically with adult T-cell leukemia, which is an endemic disease in southwestern parts of Japan. We examined the seroepidemiological characteristics of antibody to adult T-cell leukemia virus associated antigen (anti-ATLA-antibody) by the indirect immunofluorescent assay and ELISA from the healthy individuals and various diseased patients in the Republic of Korea, a country adjacent to Japan in which HTLV-1 is endemic. The results were as follows. 24 out of 9,603 individuals(0.25%) were seropiositive. The positve rate was 0.17% in males and 0.36% in females, the sex difference was female predominent relatively. HTLV-1 carriers were found 16 individuals in Seoul, 5 in Kyonggi area, 1 in Chungnam and Jonbuk, respectively, but found only 1 individual in Busan city and Jaejoo area close to southwestern parts of Japan. Positive rate to anti-ATLA-antibody seemed to be high in older age, especially at the 50s(0. 4Yo). In conclusion the prevalence rate of anti-ATLA- antibody seemed to be very low in the Republic of Korea adjacent to Japan in which HTLV-1 is endemic and no patient with adult T-cell leukemia has been found as yet. Also we noted that the Republic of Korea is not an endemic area to HTLV-1.

초내열합금 Mar-M 247 LC 에서 열처리에 의한 미세조직의 변화와 크리프특성과의 관계

김일호,최병학,강수현,조종춘,허보영,김학매 대한금속재료학회(대한금속학회) 1999 대한금속·재료학회지 Vol.37 No.3

Creep-rupture properties of a cast type Superalloy, Mar-M247LC. were studied in 760℃ and 980℃. The shape and size of γ′ particles in grains were known to have significant influence on the creep behavior and rupture life in relation to the micro-mechanism of plastic deformation. It was found that the creep properties were also affected by the cast structure which is composed of dendrite matrix and eutectic boundaries. The hardening effect of boundaries by solute segregation and eutectic phases may improve the creep resistance of grain or eutectic boundaries during creep-rupture.

Ti-6Al-4V 합금의 가공 열처리조건에 따른 기계적 특성의 변화 (1) : 인장및 파괴거동 Tensile and Fracture Behaviors

최승주,김상식,조용성,장우길,서성문 대한금속재료학회(대한금속학회) 1998 대한금속·재료학회지 Vol.36 No.12

Tensile and fracture behaviors of double-forged and aged Ti-6Al-4V alloys, with and without solution heat treatment and/or rapid cooling, were examined in the present study. Depending on the forging temperature and heat treatment condition, the microstructures of Ti-6Al-4V alloys varied greatly, including equiaxed α+transformed β. elongated α+equiaxed α, α' or acicular α in the prior β grain, and significantly affected the tensile and fracture properties at 25 and 316℃. Tensile and fracture failure modes of Ti-6Al-4V alloys with different microstructures were discussed based on the detailed fractographic examinations.

청국장의 제조방법과 이용실태에 관한 조사연구

김태영,김진숙,장창문,신선영,유선미,최정숙,박홍주 한국콩연구회 1996 韓國콩硏究會誌 Vol.13 No.2

The preparation method for traditional Chung-Kuk-Jang at home was surveyed by 241 housewives through the country using premade questionnaires. The 84.2% of total respondents prepared Chung-Kuk-Jang at home, mostly from October to December (95.5%), once or twice per year (71.9%). Soybean for Chung-Kuk-Jang had a relatively large grain size, and average soaking and boiling time were 5.8 hr and 3.6 hr, respectively. Only 31% of respondents used rice straw for Chung-Kuk-Jang fermentation and 90% of respondents fermented Chung-Kuk-Jang in the Korean under-door heating system for 3 days (53.2%) or 2 days (20.2%). Average subsidiary ingredients for Chung-Kuk-Jang making were salt (8.5%), garlic(2.2%), redpepper-powder (0.2%). After mixing all ingredients, Chuag-Kuk-Jang in clay pot was kept in a cool place (38.4%) or refrigerator (38.4%). The 58.5% of total respondents had experience of purchasing commercial Chung-Kuk-Jang, mostly is the market (51.1%) or supermarket (40.4%) and the respondents, who were low-aged or high - educational level or live in apartment purchased the commercial products more often than the others. The reasons for purchasing commercial products were convenience (40.4%), short of time(34%) and the criteria for purchasing were odor (34.8%) and taste by previous experience (28.4%). Respondents preferred vinyl packing (83.7%) and 300g pack (52.5%) for. single usage. The 45.4% of respondents were not satisfied with the commercial products and the reason for dissatisfaction was inferior taste (56.3%), especially without taste peculiar to the Chung-Kuk-Jang. The necessities for improving quality of Chung-Kuk-Jang were to mask off - flavour (52.3%) and to preserve deterioration (30.7%).

당뇨병에서의 혈장 Renin 활성에 관한 연구

이정상,이문호,김성권,최강원,표희정,박정식 대한핵의학회 1979 핵의학 분자영상 Vol.13 No.1

당뇨병에서의 고혈압 및 신합병증에 따른 Renin Angiotensin-Aldosterone계의 동태를 밝히기 위하여 40예의 당뇨병 환자에서 기저 및 furosemide 정주 2시간 후의 PRA를 측정하였다. 1) 40예의 당뇨병 환자는 신합병증과 고혈압의 유무에 따라 4군으로 분류하였으며, 임상적인 합병증이 없는 Ⅰ군에는 15명, 신합병증이 있는 Ⅱ군에는 7명, 신합병증과 고혈압이 같이 있는 Ⅲ군에는 8명, 고혈압만 있는 Ⅳ군에는 10명의 환자가 속하였다. 2) 각 군의 24시간 요중 Na배설량의 평균치 사이에는 유의한 차이가 없었다. 3) 기저 PRA치는 Ⅰ군이 1.53±1.09ng/ml/hr(Mean±S.D), Ⅱ군이 0.63±0.59ng/ml/hr, Ⅲ군이 0.79±0.62ng/ml/hr, Ⅳ군이 1.11±0.80ng/ml/hr로서 Ⅱ군과 Ⅲ군은 Ⅰ군에 비하여 유의하게 저하되어 있으나(P$lt;0.05), 다른 군들 간에는 유의한 차를 볼 수 없었다. 4) furosemide 정주 2시간 후의 PRA치는 Ⅰ군이 2.72±1.96ng/ml/hr, Ⅱ군이 0.92±0.78ng/ml/hr, Ⅲ군은 1.03±0.76ng/ml/hr, Ⅳ군은 1.73±1.39ng/ml/hr로써 Ⅰ군과 Ⅱ군사이에서만 유의한 차이를 보이고(P$lt;0.05), 다른 당뇨병 환자군 사이에서는 유의한 차를 볼 수 없었다. 5) furosemide 정주에 의한 Renin 분필 자극시험에 대한 반응도 Ⅱ군과 Ⅲ군에서는 둔화되어 있는 양상을 보이나, 시험대상도 적고하여 통계적 유의성에는 미치지 못하였다. 이상의 성적에서 신합병증이 있는 당뇨병에서는 혈장 Renin활성이 저하되며 furosemide 정주에 의한 Renin 분필자극시험에 대한 반응도 둔화됨을 알 수 있었다. 또한 당뇨병성 신합병증에 의한 고혈압에서도 혈장 Renin활성은 저하되는 경향을 보여서 이 경우의 고혈압은 Renin이외의 다른 요인이 작용할 것으로 보인다. To evaluate the renin-angiotensin-aldosterone system in diabetes mellitus, basal plasma renin activity(PRA) and its response to intravenous furosemide were determined in 40 diabetic subjects. The diabetics were divided into 4 groups according to the pressence of nephropathy and/or hypertension. Uncomplicated diabetics(Group I) were taken as control group and the results of the other groups were compared to this group. In diabetics viith nephropathy alone(Group Ⅱ), and with nephropathy and hypertension (Group Ⅲ), basal PRA values were 0.63±0.59ng/ml/hr., and 0.79±0.62ng/ml/hr., respectively, both significantly lower than control group. (1.53±1.09ng/ml/hr.). (P$lt;0.05) In both of the above groups, the responses to intravenous furosemide tended to be blunted. On the other hand, in diabetics, with hypertension only (Group Ⅳ), the basal and stimulated PRA were not significantly different from control. Above results suggests that nephropathy may be one of the factors which suppress renin activity in diabetes me.

정상인 및 고혈압환자에서의 Renin 분비자극시험에 관한 연구

이정상,고창순,이홍규,최강원 대한핵의학회 1978 핵의학 분자영상 Vol.12 No.1

저자들은 정상대조군 66예와 본능성고혈압 환자 44예등 총 110예를 대상으로 furosemide 정주후 1∼4시간의 PRA 증가양상을 3시간입위자극에 의한 PRA 변동과 비교하였으며, 이렇게 하여 얻은 결과를 24시간 요중배설량과 PRA를 대비시킨 nomogram상의 결과와 비교하였다. 1) furosemide 40mg 정주후 PRA는 2시간까지 계속 증가되었으나, 1∼2시간 사이에 모두 기저 PRA보다는 현저한 증가를 나타냄으로 furosemide 투여 1시간후의 PRA측정이 실제 임상적 응용에는 적당한 것으로 생각된다. 2) 3시간 입위에 의한 자극도 일관성있는 PRA 증가를 일으켰으나, furosemide에 의한 것보다는 증가폭이 적고, 실제 시행상 불편이 있으므로 furosemide 자극이 보다 편리하고 확실한 자극을 줄 수 있다. 3) 남녀의 성별에 의한 PRA 증가반응의 차이는 없으나 25세 이하의 연령군은 60세 이상의 연령군에 비해서 PRA 증가가 현저히 높았다. 그러나 양자간에 기저 PRA상의 차이는 발견되지 않았다. 4) furosemide 투여 1시간후의 PRA 증가폭의 하한을 1ng/ml/hr로 잡는 경우 본능성고혈압중 저 renin의 빈도는 34.1%였으며, 이중 nomogram상으로는 정상 renin으로 생각되는 예가 33.3%였다. 이러한 상위는 특히 환자의 Na 배설이 220mEg/day 이상의 고염섭취군에서 심하였다. 5) 각 renin군간에 명확한 임상적 및 검사상의 차이가 발견되지 않았으나, 저 renin군의 연령은 여타 renin군보다 유의하게 높아서 renin활성 및 분비능의 감소와 연령간에 어떤 관련이 있음을 시사하였다. To find out a convenient and reliable nethod of detecting low renin status, we employed intravenous furosemide injection as a stimulatory maneuver. The results thus obtained were compared with those from the postural stimuli and basal plasma renin activity (PRA) in relation to sodium excretion. Intravenous furosemide test was performed in 66 control subjects and 44 patients with essential hypertension. The results were as follow; 1) Mean PRA in control subjects rose from 2.5±1.95 ng/ml/hr (basal) to 4.5±2.51, 5.2±2.49 and 4.2±2.44 ng/ml/hr at 1, 2 and 3hrs after Ⅳ injection. One-hour response is more convenient in clinical practice. 2) Postural stimuli by assuming an upright posture for 3 hrs gave rise to considerable increase in PRA (4.0±2.92 from 2.4±1.85), but we found it less convenient than stimulation with furosemide. 3) The increase in PRA was much less marked in patients with essential hypertension as a whole (2.9±2.75). Hyporesponsiveness to furosemide stimuli was found in 34.1%. Of these hypers, a third had a normal basal PRA, indicating the need for this kind stimulatory procedure. 4) Younger age group showed greater renin responsiveness than older age group after furosemide stimuli. Likewise mean age of low renin patients (52.9±5.38 years old) was significantly higher than that of high and normal renin patients (44.1±13.78 years old). $quot;

유교와 교육

최근덕 한국사상사학회 1990 韓國思想史學 Vol.3 No.1

서양음악의 역사철학 : 서설

알렌,진회숙 한국음악사학회 1992 韓國音樂史學報 Vol.8 No.1

Glutaraldehyde 와 자동 세척기를 이용한 내시경 소독방법의 임상에서의 유용성

김영호,손희정,윤성원,최규완,이남용,백승운,이준행,고광철,이풍렬,이종철,송재훈,안병훈,김재준,최원혁,홍일철 대한소화기내시경학회 2001 Clinical Endoscopy Vol.22 No.6

Background/Aims: Safety of endoscopic procedures has been a major issue over the last 10 years. Most endoscopy units use 2% glutaraldehyde and automated endoscope reprocessors (AERs) for disinfecting gastrointestinal endoscopes. We attempted an in-use evaluation of the current reprocessing procedures. Methods: Thirty flexible endoscopes were randomly collected just after upper endoscopic examinations and were disinfected using 2% glutaraldehyde in an AER. Cultures were taken from biopsy channels (S-l), tip of the insertion tubes (S-2), umbilical cords (S-3), and angulation knobs (S-4). Results: In 63,3% (19/30) of endoscopes, there was no microbial contamination after disinfection procedures. The culture positive rates of S-l, S-2, S-3, and S-4 samples were 20,0%, 0.0%, 3.3%, and 20.0%, respectively. Microorganisms of 13 species were identified, but there was no pathogen related with reported infectious complications after endoscopic procedures. Conclusions: Current disinfection procedure using 2% glutaraldehyde and an AER appears to be very effective in decontaminating patient-used endoscopes. Low level microbial contamination of endoscopes after conventional reprocessing methods may not impose great risk on patients.

가족 이데올로기와 문학 연구

최시한(Choe Sihan) 돈암어문학회 2006 돈암어문학 Vol.- No.19

This thesis examines the theory and methods to study family ideology, focusing on the novel. The short story Haedogi by Choe, Seohae is examined and summarized to make a series of conclusion. Writer let himself be a problematic person in a context of history. Choe Seohae's dilemma of family is also a dilemma of a subject losing one's nation forcing him to embody it in the form of novel. His short story Haedogi is a result of historical reality of Korea when it was at the gateway to modern times; many changes and shifts and its loss of national sovereignty made a relation between family and society so confronted each other that one has to choose the only one of them. From this, socialism can be a good method to cover or solve this dilemma because it can substitute lost father with a new 'ideal father.' However, Choe's familism and conscience as an writer do not allow him to choose that way. His novels and life as an writer show us the typical response to socialism like many Korean people, who are tied up to traditional family ideology with loss of their country, did. The dilemma that someone should choose one side only instead of the other one is just concealed and rationalized without any findings to creatively solve it.