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Pixel-Structured Scintillator with Polymeric Microstructures for X-Ray Image Sensors
Im Deok Jung,Min Kook Cho,Kong Myeong Bae,Sang Min Lee,Phill Gu Jung,김호경,김성식,고종수 한국전자통신연구원 2008 ETRI Journal Vol.30 No.5
We introduce a pixel-structured scintillator realized on a flexible polymeric substrate and demonstrate its feasibility as an X-ray converter when it is coupled to photosensitive elements. The sample was prepared by filling Gd2O2S:Tb scintillation material into a square-pore-shape cavity array fabricated with polyethylene. For comparison, a sample with the conventional continuous geometry was also prepared. Although the pixelated geometry showed X-ray sensitivity of about 58% compared with the conventional geometry, the resolving power was improved by about 70% above a spatial frequency of 3 mm-1. The spatial frequency at 10% of the modulation-transfer function was about 6 mm-
Han, Jung-Wook,An, Jong-Deok,Jana, R.N.,Jung, Kyung-Na,Do, Jung-Hwan,Pyo, Seung-Moon,Im, Chan The Polymer Society of Korea 2009 Macromolecular Research Vol.17 No.11
This study examined the charge carrier photogeneration and hole transport properties of blends of poly (9-vinylcarbazole) (PVK), $\pi$-conjugated polymer, with different weight proportions (0~29.4 wt%) of (PEA)$VOPO_4{\cdot}H_2O$ (PEA: phenethylammonium cation), a novel organic-inorganic hybrid material, using IR, UV-Vis, and energy dispersive spectroscopy (EDS), thermogravimetric analysis (TGA), steady state photocurrent (SSPC) measurement, and atomic force microscopy (AFM). The SSPC measurements showed that the photocurrent of PVK was reduced by approximately three orders of magnitude by the incorporation of a small amount (~12.5 wt%) of (PEA) $VOPO_4{\cdot}H_2O$, suggesting that hole transport occurred through the PVK carbazole groups, whereas a reverse trend was observed at high proportions (>12.5 wt%) of (PEA)$VOPO_4{\cdot}H_2O$, suggesting that transport occurred via (PEA)$VOPO_4{\cdot}H_2O$ molecules. The transition to a trap-controlled hopping mechanism was explained by the difference in ionization potential and electron affinity of the two compounds as well as the formation of charge percolation threshold pathways.
체계적 문헌고찰을 통한 국내 치과공포 연구 동향분석 (2007-2017)
임애정 ( Ae-jung Im ),김세은 ( Se-eun Kim ),김현지 ( Hyun-ji Kim ),박덕현 ( Deok-hyun Park ),박민영 ( Min-young Park ),박소영 ( So-young Park ),이동균 ( Dong-gyun Lee ),홍의정 ( Eui-jeong Hong ),임희정 ( Hee-jung Lim ) 한국치위생학회(구 한국치위생교육학회) 2018 한국치위생학회지 Vol.18 No.5
Objectives: The purpose of this study was to investigate the overall research trends and factors influencing dental fears in the last 10 years (2007-2017) and provide recommendations for future research. Methods: The literature review focused on dental fear research in Korea. Inclusion criteria of selected studies were as follows: studies that examined fear in middle school students or older, studies undertaken between 2007-2017, and studies that examined trends and factors relating to dental fears. Results: Findings from this literature review showed that the most commonly used tool for measuring dental fear was the Dental Fear Survey (DFS). A lack of trust towards the dentist increased dental fear among patients. Women managed fear better than men. Past pain experiences increased dental fear. The most frequent intervention for reducing fear was sound (41.7%). Most of the intervention studies demonstrated a reduction of fear, with the exception of interventions using ear plugs. Fear was increased in studies involving ear plugs. Conclusions: Based on the results of the study, specific measures should be taken to alleviate past pain experiences, such as the fear of anesthetic injections and sensations of the dental drill. Continuous research is needed to reduce dental fear.
PDMS 유연 몰드를 이용한 구리 마이크로 메쉬 시트의 제작
정순녕(Sun Nyeong Jung),강창근(Chang Kun Kang),정임덕(Im Deok Jung),배공명(Kong Myeong Bae),박치열(Chi Yeol Park),정필구(Phill Gu Jung),고종수(Jong Soo Ko) 대한기계학회 2007 大韓機械學會論文集A Vol.31 No.12
A unique fabrication method for a copper micromesh is proposed and demonstrated. A PDMS mold was fabricated using a microcasting process and then used as a flexible mold in copper electroplating. The fabricated copper micromesh was well formed and connected without any cracks within the entire mold area. The experimental results verified that the fabricated features of the copper micromesh accurately followed the shape of the microstructures of the PDMS mold. This unique fabrication method provides an easy yet precise means of producing three-dimensional metal microstructures.
Potential Role of S100A8 in Cutaneous Squamous Cell Carcinoma Differentiation
( Jung Min Shin ),( In Kyu Chang ),( Young Ho Lee ),( Min Kyung Yeo ),( Jin Man Kim ),( Kyung Cheol Sohn ),( Myung Im ),( Young Joon Seo ),( Chang Deok Kim ),( Jeung Hoon Lee ),( Young Lee ) 대한피부과학회 2016 Annals of Dermatology Vol.28 No.2
Background: S100A8 is differentially expressed in various cell types and is associated with a number of malignant disorders. S100A8 may affect tumor biology. However, its role in cutaneous squamous cell carcinoma (SCC) is not well established. Objective: This study aims to investigate the relationship between S100A8 and cutaneous SCC development. Methods: We performed immunohistochemical staining to detect S100A8 expression in facial skin specimens of premalignant actinic keratosis (AK), malignant SCC, and normal tissues. In addition, we utilized postconfluence and high calcium- induced differentiation in a culture system model. Furthermore, we constructed a recombinant adenovirus expressing GFP-tagged S100A8 to investigate the role of S100A8 in SCC cell differentiation. Results: S100A8 was significantly overexpressed in human cutaneous SCC compared to that in normal and AK tissues. S100A8 was gradually upregulated in SCC cells in a post-confluence-induced differentiation model. Overexpression of S100A8 in SCC cells induced by adenoviral transduction led to increased expression levels of differentiation markers, such as loricrin, involucrin, and filaggrin. S100A8 overexpression also increased loricrin and involucrin luciferase activity. Conclusion: S100A8 regulates cutaneous SCC differentiation and induces well-differentiated SCC formation in skin.(Ann Dermatol 28(2) 179∼185, 2016)
Deok Yong Sim,Hyo-Jung Lee,Eunji Im,Ji Eon Park,Chi-Hoon Ahn,Ju Eun Baek,Kyung Seok Kim,Dae-Yong Lee,Sung-Hoon Kim,Bum Sang Shim 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
Though Cornin is known to induce angiogenic, cardioprotective and apoptotic effects, there is no report on antitumor effect of Cornin in prostate cancers yet. Thus, in the present study, the apoptotic mechanism of Cornin was investigated in androgen-dependent prostate cancer cells in association with STAT3/AR signaling axis. Cornin exerted significant cytotoxicity, induced sub-G1 population, and decreased the PARP and caspase3 in LNCaP cells. Consistently, Cornin downregulated the expression of AR, PSA and 5α-Reductase in LNCaP cells. Furthermore, Cornin inhibited phosphorylation of STAT3 and also disrupted the binding of STAT3 and AR in LNCaP cells. Notably, Cornin upregulated the level of miR-193a-5p in LNCaP cells. Consistently, miR-193a-5p mimic exerted cytotoxicity, suppressed AR, STAT3 and pro-PARP and suppressed the expression of AR and 5α-Reductase at mRNA level, whereas miR-193a-5p inhibitor reversed the ability of Cornin to attenuate AR, PSA and STAT3 in LNCaP cells. Overall, our findings provide scientific evidence that miRNA-193a- 5p mediated inhibition of STAT3/AR signaling axis is critically involved in Cornin induced apoptosis in prostate cancers.
P198 Effects of propolis on epidermal keratinocytes
( Jung-min Shin ),( Jeong-min Ha ),( Mi-yeung Kim ),( Na-rae Kim ),( Hea-eul Lee ),( Myung Im ),( Young Lee ),( Chang-deok Kim ),( Young-joon Seo ),( Jeung-hoon Lee ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2
<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Propolis is a natural resinous mixture, produced by honey bees, of saliva and beeswax with exudate gathered from parts of plants, buds, sap, or other botanical sources. Although propolis is widely used practically, little is known about the potential effects of propolis on skin cells. Objectives: In this study, we investigated the effects of propolis on cultured keratinocytes. Methods: To confirm the effect of propolis, we evaluate skin hydration and inflammation using biochemical techniques and animal models such as aquaporin3 (AQP3) expression, a channel for glycerol, in human keratinocytes and transepidermal water loss (TEWL). Results: Propolis increased the expression of AQP3. Consistent with this result, propolis increased [3H]glycerol uptake in keratinocytes. However, propolis did not affect TEWL when topically applied onto the tape-stripped mouse skins. Finally, in poly(I:C) induced-innate immune response, propolis significantly decreased the mRNA expression of pro-inflammatory cytokines, such as IL-8 and TNF-α. Conclusion: These data demonstrate that propolis has a variety of effects on epidermal keratinocytes, suggesting that it can be used as an ingredient for cosmeceuticals targeting various dermatological events.
Regulation of lipid production by light-emitting diodes in human sebocytes.
Jung, Yu Ra,Kim, Sue Jeong,Sohn, Kyung Cheol,Lee, Young,Seo, Young Joon,Lee, Young Ho,Whang, Kyu Uang,Kim, Chang Deok,Lee, Jeung Hoon,Im, Myung Springer-Verlag 2015 Archives of dermatological research Vol.307 No.3
<P>Light-emitting diodes (LED) have been used to treat acne vulgaris. However, the efficacy of LED on sebaceous lipid production in vitro has not been examined. This study investigated the efficacy of 415 nm blue light and 630 nm red light on lipid production in human sebocytes. When applied to human primary sebocytes, 415 nm blue light suppressed cell proliferation. Based on a lipogenesis study using Oil Red O, Nile red staining, and thin-layered chromatography, 630 nm red light strongly downregulated lipid production in sebocytes. These results suggest that 415 nm blue light and 630 nm red light influence lipid production in human sebocytes and have beneficial effects on acne by suppressing sebum production.</P>