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      • 가감목방기탕(加減木防己湯)이 흰쥐의 Adjuvant 유발 관절염에 미치는 영향

        황덕순,김순중,서일복,Hwang, Duk-Soon,Kim, Sun-Jung,Seo, Il-Bok 대한한의정보학회 2005 大韓韓醫情報學會誌 Vol.11 No.1

        Objectives : This study was to investigate the effect of Kagammokbanggi-tang on the Freund's Complete Adjuvant(FCA)-induced arthritis in rats. Methods : Arthritis was induced by intradermal injection of FCA into base of tail. Arthritic rats were divided into control(n=10) and sample(n=10) group. Control group was taken normal saline for twenty days and sample group was taken extracts of Kagammokbanggi-tang for same duration. Normal group(n=10), non-arthritic group, was injected with mineral oil and was taken normal saline for twenty days. Body weight, paw edema volume and ankle joint thickness were measured at 0, 10, 15, 20 days after treatment. $TNF-{\alpha}$, $IL-1{\beta}$, IL-6, $PGE_2$ in synovia were analysed by ELISA at 20 days after treatment. Histochemical investigation of NADPH-d in the PAG and histopathological study on the ankle joint were performed at 20 days after treatment. Results : Paw edema volume, ankle joint thickness, $TNF-{\alpha}$, $IL-1{\beta}$, IL-6, $PGE_2$, NADPH-d of sample group were significantly decreased compared with control group. Conclusions : These results indicated that Kagammokbanggi-tang has antiarthritic and analgesic effects, and inhibited expression of NOS on the progression of FCA- induced arthritis in rats.

      • 한강 하류 김포평야의 최종빙기 이래 퇴적환경변화

        황상일,김혜령,윤순옥 경북대학교 사회과학대학 지리학과 2003 地理學論究 Vol.- No.23

        한강하류부에 위치한 김포시 고촌면 김포평야의 충적충과 사면퇴적충에서 퇴적상 분석 및 화분 분석을 실시하여 식생환경, 해면변동, 기후변화와 같은 자연환경인화를 검토하고 이것을 선사시대 인간활동과의 관계에서 살펴보았다. 최종빙기 이래 형성된 연구지역의 퇴적상은 빙기의 선상지성사면퇴적층과 흘로세 충적충으로 구분되며, 화분분석은 흘로세 충적충의 유기질이 다소 포함된 회색실트충, 분해되지 않은 토탄충, 분해된 토탄충에서 이루어졌다. 화분조성은 흘로세 중기 이후 해면미변동을 반영하며, 화분대GP-Ⅰ은 흘로세 해진의 영향으로 수심이 있는 저습지 환경에서 Alnus를 중심으로 한 목본 우점기에 퇴적되었고, 화분대GP-ll시기는 해면의 지속적인 정체와 하강에 따른 지하수위 저하 그리고 활발해진 인간활동의 영향으로 목본이 크게 줄고, 포자와 초본류가 우점하게 되었다. The environmental change such as vegetation environment, sea-level change, climate change and human impact was restored at Gimpo alluvial plain on the upper Han river according to the results of sedimentary facies and pollen analysis. The sedimentary facies which has been constructed since the last glacial stage is composed of the hillslope deposits as the alluvial fan during the glacial stage and Holocene alluvium. Materials for pollen analyses were sampled from gray organic silt layer, peat I layer(abundant fibroid material included the branches of trees and roots of grasses) and peat Ⅱ layer(decomposed peat including organic clay) in the alluvium of the Holocene. The change of the pollen composition reflected sea-level change and vegetation environment during the Holocene. Pollen zone GP-Ⅰ was the period of AP-dominance, including mostly Alnus. Study area was under the lagoon or swamp environment influenced by Flandrian transgression. Pollenzone Ⅱ was the period of Spore & NAP-dominance. It represents that vegetation environment was changed to drier condition by falling the surface of ground-water caused by sea-level regression after long-term stability, and influenced of human activity.

      • Perovskite형 복합산화물 LnCoO_3(Ln=Pr,Nd)의 환원성

        박일현,황호순,최원석 성균관대학교 기초과학연구소 1990 論文集 Vol.41 No.1

        Nonstoichiometry, thermal stability and reduction reaction of Perovskite-type LnCoO_(3-y)(Ln=Pr, Nd) mixed oxides under static H2 atmosphere were investigated by means of temperature-programmed reduction(TPR) method, X-ray diffraction, Infrared spectroscopy and Scanning electron microscopy. Nonstoichiometry of these mixed oxides were determined as PrCoO_2.94, NdCoO_2.99, respectively. According to kinetic studies, these mixed oxides were revealed that the first reduction stages of LnCoO_(3-y)(Ln=Pr,Nd) oxides were followed by Ginstling-Brounshtein equation indicating three dimensional diffusion of reactant. The second reduction stages were controlled by formation and growth of reaction nuclei via the reaction interface. Activation energies of the first reduction stages of LnCoO_(3-y)(Ln=Pr,Nd) were 22.2, 26.5 kcal/mole, respectively and for the second reduction stages of LnCoO_(3-y)(Ln=Pr,Nd) were 33.4, 29.1 kcal/mole, respectively.

      • KCI등재

        홍화씨 열수 추출 분말을 이용한 우리 밀 라면의 제조

        심지연,황은희,이일환,장혜순 동아시아식생활학회 2005 동아시아식생활학회지 Vol.15 No.1

        The purpose of this study was to make ramyon from Korean cultured wheat by adding with hot water extract powder from safflower seed in order to add the value of it. The cooking quality, instrumental texture and sensory characteristics of ramyon were analyzed. The ramyons with 0.1%, 0.3%, 0.5%, and 0.7% of hot water extract powder(HEP) from safflower seed, control, and those with 3% and 5% of dried powder(DP) from safflower seed were compared. The yield of HEP was 7.8%. Lightness, redness, Max. weight, strength, hardness, adhesiveness, cohesiveness and springiness were measured. As the amounts of HEP and DP was increasing, ramyons smelled stronger and was getting harder and chewier, while became less transparent and had no difference in elasticity and adhesiveness. In overall acceptability, both control and ramyon with HEP had similar points. From three important factors, appearance, color and smell to make ramyon more acceptable, addition of 0.3~0.5% of hot water extract powder from safflower seed was found to be the best. However, further studies on smells are needed to make processed foodstuffs with safflower seed.

      • KCI등재

        지역사회 정신의학 전공의 교육과정 실태조사

        홍진표,황순찬,이영문,이선형,신나리,이종일,박종익,장동원,정인원 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

        Objectives : There is a increasing need to recruit and retain more psychiatrists who can plan and implement organized programs to work with chronic mentally ill patients in community settings. The aim of study is to discover what training is currently in place to prepare psychiatrist for work in "community" or "public" settings. Methods : Survey questionnaires were mailed to 85 residency training directors and 10 leaders of community mental health in 2005. Response rate was 75%. Results : Academic seminar about community mental health were not administered to residents in 63% of training hospitals. Forty one out of 64 training hospitals had community mental health rotation programs, Community mental health center (50%) and day hospital (36%) were the most common type of programs. Few general hospital had affiliation with community mental health programs. The amount of time for clinical rotation varied from less than three months part time to 6 months fulltime, with most frequent form of one day per week for three month in second or third year of psychiatry residents. Conclusion : Further steps are needed to improve residency training curricula and to encourage well qualified psychiatrist to choose careers in community psychiatry.

      • 光波長이 오이(Cucumis sativus L.) 플러그苗의 生長에 미치는 影響

        용영록,전지영,황세진,김일섭,정천순 강릉대학교 동해안지역연구소 2000 東海岸硏究 Vol.11 No.1

        This research was carried to find out the optimum artificial light condition for plug seedling production of high quality cucumber through investigating growth response of the seedling by both light wave length and treatment period. The treatment with blue and red fluorescent lamp increased the fresh weight involving hypocotyl and root and controlled the elongation of hypocotyl, compared with other treatments. The 30-day-old seedling treatment with blue and red light for 12 hours showed that vegetative growth including root, stem and leaves was better than that of seedling treated with other lamps. Seedling under blue and red light for 12 hours grew 60.0mm and 0.55g in length and weight of hypocotyl. respectively, Hypocotyl length and weight were 44.9mm and 0.62g when seedling was grown under above light condition for 6 hours. Total chlorophyll contents of hypocotyl were highest in the light mixing treatment, and this accelerated greening. Morphological characteristics by investigating cross and longitudinal section of 30-day-old cucumber seedling treated with the mixing fluorescent lamps indicated that epidrmis tissues were usually single layer and thicker, resulting in small, compact and non-intercellular spaces of cells. On the other hand, epidermis tissues of the control composed of large, longer and round cells and cortex tissues showed large intercellular spaces between cells. Longitudinal section of photo-treated hypocotyl showed that there were more shorter cells and non-intercellular spaces of cells than untreated tissues. As a result, blue and red light mixing treatment controled the cell elongation of seedling hypocotyl, resulting in shortening hypocotyl of cucumber seedling.

      • KCI등재후보

        하치조신경 및 설신경 손상 평가를 위한 한국인 정상 성인의 하순-이부 및 혀의 감각 조사

        이종호,이세영,송승일,이은진,안강민,김성민,명훈,황순정,서병무,최진영,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

        In the head and neck area, there are so many sensory nerves, which are sometimes injuried iatrogenically or inadvertently so that involved patients complained of the loss of sensations. In such cases, it is important to judge the degree of injuries and regeneration of nerve for better diagnosis and treatment. Seddon and Sunderland's classification, which is commomly used, is focused on histological change and nerve conduction. As times goes by, it is difficult to access patient's sensory disturbance by this method. Until now, so many methods such as contract threshold, direction, two-point discrimination, pin prick, thermal discrimination and current perception threshold have been introduced for sensory evaluation. However, there hasn't been enough information regarding each methodology nor integrated standard methodology for the measurement. the purpose of this study is to get Korean adult normative sensory values of lower lip,chin and tongue using modified methods of contact thershold, ditection, two point discrimination, pin prick, thermal discrimination and assess degree of regeneration of sensory nerve damage.

      • Genome-wide structural variation by different types of ionizing irradiation sources

        Soon-Jae Kwon,Hong-Il Choi,Jung Eun Hwang,Injung Jung,Sung Min Han,Jin-Baek Kim,Joon-Woo Ahn,Sang Hoon Kim,Yeong Deuk Jo,Si-Yong Kang,Dong-Sub Kim 한국육종학회 2015 한국육종학회 심포지엄 Vol.2015 No.07

        To define whole genome-level of structural variation by ionization energies and radiation doses in plant, the seeds of Ilpum rice cultivar were acutely irradiated with gamma rays (100Gy, 200Gy, and 400Gy) and ion-beams (20Gy, 40Gy, and 80Gy), respectively. Six M1 rice plants were re-sequenced by Hi-Seq2500 with Ilpum cultivar as control. The average sequencing coverage of the individuals was 10.6X, and the average mapping rate to the rice reference genome (IRGSP-1.0) sequence was 96.95%. The individual plants were irradiated with gamma-400Gy and ion-50Gy had highest variation of SNP with 471,837 and 469,147, respectively. The number of insertion/deletion was 77,500 and 77,106, the synonymous and frame-shift were 7,859 and 7,763 in above two individuals. Although high genome variation shown between Ilpum cultivar and irradiated individuals, there were non-correlation between number of variation and radiation doses. However, five individuals, except ion-20Gy, showed 33 common variant blocks (CVBs) spanning 6 Mb in whole rice genome (1.6%). The CVBs were distributed on 12 rice chromosomes, Chromosome 6 had biggest CVB (5 blocks, 1.3Mb), whereas chromosome 9 had smallest CVB (0.01Mb). Total five hundred fifty one genes were in CVBs which can regard radiation sensitive genes or may be regarded as radiation hot spots in rice genome. This study will contribute to the improvement of the radiation mutation breeding research in genetic and genomic aspect.

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