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The Effect of Mechanochemical Treatment of Supported Catalyst on the Growth of Carbon Nanotubes
Yu, Hyung-Kyun,Kim, Jung-Sik,Lee, Byung-Il,Saito, Fumio,Ryu, Ho-Jin Korean Chemical Society 2004 Bulletin of the Korean Chemical Society Vol.25 No.5
As an pretreatment, a Fe$(NO_3)_3{\cdot}9H_2O-Al(OH)_3$mixture was ground by a high energy mill and used as a supported catalyst for the growth of carbon nanotubes by a thermal CVD. The crystal structure of the catalyst disordered by the grinding influenced significantly the synthesis of carbon nanotubes in a thermal CVD.
Lee, Hyung-Gon,Sung, Yu-Taek,Lee, Yun-Kyun,Kim, Woo-Nyon,Yoon, Ho-Gyu,Lee, Heon-Sang The Polymer Society of Korea 2009 Macromolecular Research Vol.17 No.6
The effects of maleic anhydride-grafted polypropylene (PP-g-MAH) addition on polypropylene (PP) and poly(acrylonitrile-butadiene-styrene) (ABS) blends were studied. Blends of PP/ABS (70/30, wt%) with PP-g-MAH were prepared by a twin-screw extruder. From the results of mechanical testing, the impact, tensile and flexural strengths of the blends were maximized at a PP-g-MAH content 3 phr. The increased mechanical strength of the blends with the PP-g-MAH addition was attributed to the compatibilizing effect of the PP and ABS blends. In the morphological studies, the droplet size of ABS was minimized (6.6 ${\mu}m$) at a PP-g-MAH content of 3 phr. From the rheological examination, the complex viscosity was maximized at a PP-g-MAH content of 3 phr. These mechanical, morphological and rheological results indicated that the compatibility of the PP/ABS (70/30) blends is increased with PP-g-MAH addition to an optimum blend at a PP-g-MAH content of 3 phr.
Moon, Hyung-Bae,Yu, Dae-Yeul,Lee, Kyung-KWang,Han, Yong-Mahn,Yun, Ki-Jung,Han, Won-Cheol,Kim, Bo-Yong,Chung. Yung-Jin,Shin, Dae-Kyun 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.2
B형 간염바이러스(HBV) 감염은 만성간염, 간경화증, 및 간암의 발생과 밀접한 관계를 가지고 있으며, HBV에 존재하는 x항원(HBx)은 HBV 유전자의 발현이나 HBV 증식에 관여할 뿐 아니라 간세포암의 발생에 중요한 역할을 한다고 알려져 있다. 한편 분자생물학적으로 클론된 유전인자들을 포유동물의 germline에 이식하여 이식된 유전인자가 다음세대로 유전되게 하여 인체 질환을 실험동물에 유발시키는 형질전환동물 기법이 개발된 후, 인체질환의 연구에 형질전환동물이 많이 이용되고 있다. 이에 따라 HBx와 간암의 발생관계를 연구하기 위하여 HBx 형질전환 마우스를 개발한 결과 간세포암이 발생하여 이들에 대한 병리학적 및 면역조직화학적 연구를 시행한 결과는 다음과 같다. 1. 4개월부터 HBx 형질전환 마우스 모든 예에서 간세포의 공포성 변화 및 다양한 크기의 핵을 가진 변형세포 군집(Altered foci)이 관찰되었으며, 6개월부터는 육안적으로 종양은 발견되지 않지만 조직학적으로 간세포암의 특성을 보인 소결절성 병변(small nodular lesions)이 75%의 동물에서 관찰되었으며, 11개월부터 육안으로 확인 가능한 간세포암이 60%의 실험동물에서 관찰되었다. 2. 소결절성 병변 및 간세포암의 조직학적 특징은 다양한 형태 및 과염성 핵을 가지고, 핵과 세포질의 비는 감소하였으며, 간혹 비정상적인 핵분열이 관찰되었지만, 종양주위의 섬유화는 관찰되지 않았고, 이들 병변에서 증식세포핵항원 (Proliferating cell nuclear antigen)은 현저히 증가하였다. 3. HBx 단백에 대한 면역조직화학 염색 결과 변형세포군집, 작은 결절성 병변 및 간세포암 모두에서 HBx 양성소견을 나타냈으며 이의 분포양상은 비특이적이었다. 4. 유식세포분석기를 이용한 DNA ploidy 검사에서 변형세포군집 및 소결절성 병변에서는 DNA 2배수성 또는 4배수성이 관찰되었으며, 간세포암 3예 중 2예에서는 비배수성을 나타냈다. 이상의 결과로서 HBx 형질전환마우스에서 간세포암의 발생이 확인되었으며, HBV 감염에 의해 간암이 발생되는 과정에서 HBx 단백이 중요한 역할을 함을 알 수 있었고, HBx 형질전환 마우스는 간암의 연구에 중요하게 이용될 수 있을 것으로 사료되었다. Chronic infection with hepatitis B virus (HBV) is associated with a high incidence of liver disease, including chronic hepatitis, liver cirrhosis and HCC (HCC). The hepatitis B virus-encoded X antigen (HBx) stimulates virus gene expression and replication, which may be important for the establishment and maintenance of the chronic carrier state. The HBx protein, acting as a transcriptional transactivator of viral genes, may alter host gene expression and lead to the development of HCC. It has been reported by Kim et al in 1991 that HBx transgenic mice can have HCC. However Lee et al could not find HCC in their transgenic mouse system using the HBx gene. To confirm whether HBx could cause HCC in transgenic mice and present a useful model system for defining the molecular events for the transformation of HCC. We recently have generated transgenic mice by introducing HBx gene of the HBV into the mice. This study was carried out to examine the histopathologic and immunohistochemical characteristics of the liver in newly developed HBx transgenic mice. The incidence of HCC after 11 months was 60% (3/5). HCC were identified by gross examination and that indicates pleomorphic or hyperchromatic nuclei and partially infiltrative growing without surrounding fibrosis and that have DNA aneuploidy by flow cytometry in two of three cases of HCC. The incidence of small nodular lesions after 6 months was 75%(6/8) in the HBx transgenic mice, but small nodular lesions were not identified by gross examination and had same histological characteristics to HCC. Altered foci which revealed vacuolar changes in the cytoplasm of hepatocytes were found in all HBx transgenic mice from 4 months. DNA diploidy or tetraploidy were found in the tissue of the altered foci and small nodular lesions. The proliferation cell nuclear antigen (PCNA) markedly increased in small nodular lesions and HCCs in the transgenic mice. The HBx protein was expressed in the cytoplasm of all lesions including altered foci, small nodular lesions and HCC. These result indicated HCC can develop in the HBx transgenic mice and suggested that HBx protein can make the hepatocytes more susceptible to secondary events in hepatocarcinogenesis after HBV infection in human beings.
Injection Molding of Vertebral Fixed Cage Implant
Yoo, Kyun Min,Lee, Seok Won,Youn, Jae Ryoun,Yoon, Do Heum,Cho, Yon Eun,Yu, Jae-Pil,Park, Hyung Sang The Korean Fiber Society 2003 Fibers and polymers Vol.4 No.2
A vertebral cage is a hollow medical device which is used in spine forgery. By implanting the cage into the spine column, it is possible to restore disc and relieve pressure on the nerve roots. Most cages have been made of titanium alloys but they detract the biocompatibility. Currently PEEK (polyether ether ketone) if applied to various implants because it has good properties like heat resistance, chemical resistance, strength, and especially biocompatibility. A new shape of vertebral cage is designed and injection molding of PEEK is considered for production. Before injection molding of the cage, it is needed to evaluate process conditions and properties of the final product. Variables affecting the shrinkage of the cage are considered, e.g., injection time, packing pressure, mold temperature, and melt temperature. By using the numerical simula-tion program, MOLDFLOW, several cases are studied. Data files obtained by MOLDFLOW analysis are used for stress anal-ysis with ABAQUS, and shrinkage and residual stress fields are predicted. With these results, optimum process conditions are determined.
오수수와 그 분획물이 흰쥐의 흉부대동맥과 복대동맥에 미치는 혈관이완효과
김형환 ( Hyung Hwan Kim ),조남훈 ( Nam Hoon Cho ),김완기 ( Wan Gi Kim ),이상준 ( Sang Jun Lee ),유익동 ( Ik Dong Yu ),안덕균 ( Duk Kyun Ahn ),최호영 ( Ho Young Choi ) 대한본초학회 2003 大韓本草學會誌 Vol.18 No.1
N/A Objectives : We have examined the relaxational response to the methanol extract of Osusu in isolated thoracic aorta and abdominal aorta from sprague dawley (SD) rat. Methods : Rat thoracic aorta and abdominal aorta were investigated in vessel segments suspended for isometric tension recording by polygraph. To compare the vasodilation effect, put Osusu extract and fractions into them which vessels were precontracted by 5-hydroxytryptamine (5-HT). Results : We found out this result ; the thoracic aorta segments were responded to Osusu with a dose-dependent and concentration-dependent vasorelaxation. The thoracic aorta and abdominal aorta segments were responded to Osusu with a dose-dependent vasodilation. The 5-HT induced vasocontraction at 10^-5M were vasodilated such as 96.8% in thoracic aorta with 30 mg/ml Osusu (Root). Addition of 10 mg/ml Osusu in thoracic aorta which was precontracted by the 5-HT at 10^-5M were come out differently 44.5% (fr. 1; 80% methanol fraction), 56.4% (fr. 2; hexane fraction), 7.2% (fr. 3; chloroform fraction), 16.8% (fr. 4; ethyl acetate fraction), 54.9% (fr. 5; butanol fraction) and 18.3% (fr. 6; water fraction). Osusu (1 mg/ml) in abdominal aorta which was precontracted by the 5-HT at 10^-5M were come out differently 87.1% (fr. 1; 80% methanol fracton), 76.9% (fr. 2; hexane fraction), 47.2% (fr. 3; chloroform fraction), 63.2% (fr. 4; ethyl acetate fraction), 25.2% (fr. 5; butanol fraction) and 34 9% (fr. 6; water fraction). Conclusion : Osusu methanol extract and fractions-induced relaxation in the isolated rat thoracic aorta and abdominal aorta were come out be dose-dependent relaxation.
췌장 가성낭종 내에 완전 삽입된 Pigtail 스텐트의 올가미를 이용한 교정
김유경,김주현,박현철,박동균,강동훈,김선숙,최덕주,박종재,윤형선 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.2
Endoscopic drainage of pancreatic pseudocysts is a new nonsurgical treatment modality. Among the cystogastrostomy and stent related complications, proximal migration of stent is rare and the correction of inserted stent into a pseudocyst is very difficult. We report a correction of an incidentally inserted pigtail stent into pseudocyst using a polypectomy snare.
양잿물에 의한 식도협착에서 식도풍선확장술과 일시적 EsophaCoilTM 인공식도관 삽관술의 병합요법 1예
김유경,김주현,박현철,박동균,김선숙,최덕주,박종재,장호열,윤형선 대한소화기내시경학회 1996 Clinical Endoscopy Vol.16 No.6
Swallowing caustic materials may produce full-thickness burn and loss of esophageal function. Caustics, both acid and alkalis, can corrode and destroy living tissue. Full-thickness burn of esophiageal epithelium causes severe stricture which frequently requires surgical repair. Recently, non-operative dilatation of luminal stenosis has been utilized. Esophageal endoscopic endoprosthesis has been used widely in malignant esophageal stricture but not in benign stricture. In recurrent benign esophageal stricture following repetitive balloon dilatation, we experienced a case of an 18-year old woman with severe stricture which was successfully managed by esophageal endoprosthesia So we report this case with the review of the literature.