妊娠 第9 個月에 倂發한 Hirschsprung's Disease의 1例

申鉉卓,張潤錫,申旻雨,朴吉秀 大韓産婦人科學會 1963 大韓産婦人科學會雜誌 Vol.6 No.6

발치와의 치유과정에서 교원질 및 비교원단백질의 분포에 관한 면역조직화학적 연구

오화탁,김현수,주성숙,신제원 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

During tooth socket healing, the coagulum in the socket is replaced by fibrous connective tissue which undergoes mineralization and eventually becomes bone. Using this model, the healing process of the tooth socket and the role of type I collagen(CI), fibronectin(FN), bone sialoprotein(BSP), and osteopontin(OP) in the process were studied. Thirty Sprague-Dawley rats weighing 130-150gm were fed fi -aminopropionitcille for 5days before extraction of the first maxillary molars, and sacrified by perfusion with 4% paraformaldehyde at 1, 3, 5, 7, and 10days after tooth extraction. The socket and surrounding tissues were cut, demineralized, dehydrated and embedded in paraffin. For morphological observation, the sections were stained by Azan. Immunostaining of the ECM components was achieved by the avidin-biotin complex method. The results as follows; 1. Morphology of the tooth socket 1day after tooth extraction. The socket was filled with blood coagulum which was composed of densly aggregated red blood cells, platelets and fibrin network. 2. Morphology of the tooth socket 3days after tooth exyraction. A large portion of the coagulum was replaced by fibrous connective tissue contains a large number of fibroblasts, come from periphery of the socket. 3. At 5days, the newly formed bone demonstrated the highest proliferation activity. At 7days, the soclet was occupied with new bone. 4. Type I collagen was observed in the newly formed connective tissue and around the new bone. fiber. 5. Intensive staining for fibronectin was observed in granulation tissue, especially around blood vessels as well as inflammatory cells. 6. Strong immunostaining for bone sialoprotein and osteopontin was found in osteoblasts and new bone, while weaker staining was observed on dense connective tissue. 7. These data suggest that collagen and noncollagen proteins (FN, BSP, OP) an important role daring socket healing.

서울시 일부 대기 중 라돈농도의 분포에 관한 연구

김윤신,이철민,김현탁,이홍석,박태술 한양대학교 환경및산업의학연구소 2000 環境과 産業醫學 Vol.9 No.1

A study of atmospheric radon concentrations survey in Korea, Seoul was carried out with ERM(Electrostatic Radon Monitor) from October 1998 to September 1999. The mean of atmospheric radon concentrations 4.79Bq/㎥ at Seoul. Radon concentration were distributed 3.65-8.71Bq/㎥. The seasonal pattern seems to be relatively higher during the autumn and relatively low during the spring. The result from correlation analysis was significant obtained between atmospheric radon concentrations and meteorological factor.

집적화된 실리콘 압력센서의 출력전압 보상파라미터 추출 및 그 특성

이보나,김건년,박효덕,신상모,이경탁,김찬,권혁채,이상조,박현주 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

An integrated silicon pressure sensor has been designed, fabricated and tested. The signal conditioning circuits were designed to include calibration and temperature compensation of output voltage through trimming of diffusion and ion-implanted resistors. Before trimming of resistors, the compensation parameters such as pressure sensitivity, temperature coefficient of pressure sensitivity, temperature coefficient of piezoresistors and pressure sensitivity of piezoresistors were measured. Then offset voltage, span, and temperature coefficients of offset voltage and span were calibrated by trimming of resistors. The measured output voltage met our design specification and simulation value above room temperature. But, the measured output voltage at -30°C deviated from our design specification and simulation value because the offset voltages were found to vary randomly as a function of temperature.

Effect of the calcineurin inhibitor FK506 on K+-Cl- cotransporter 2 expression in the mouse hippocampus after kainic acid-induced status epilepticus.

Shin, Hyun Joo,Jeon, Byeong Tak,Kim, Jungmee,Jeong, Eun Ae,Kim, Myeung Ju,Lee, Dong Hoon,Kim, Hyun Joon,Kang, Sang Soo,Cho, Gyeong Jae,Choi, Wan Sung,Roh, Gu Seob Springer 2012 Journal of neural transmission Vol.119 No.6

<P>Calcineurin (CaN)-mediated excitotoxicity impairs 관-aminobutyric acid (GABA) transmission and induces neuronal apoptosis. Ca(2+)-dependent K(+)-Cl(-) cotransporter 2 (KCC2) participates in GABAergic inhibitory transmission. However, the mechanism by which CaN mediates GABA receptor-mediated KCC2 in seizures is not fully understood. In the present study, we investigated the altered expression of KCC2 and the effects of the CaN inhibitor FK506 on KCC2 expression in the mouse hippocampus following kainic acid (KA) treatment. FK506 was injected twice 24 h and 30 min before KA treatment and then mice were treated with KA and killed 2 days later. FK506 had anticonvulsant effect on KA-induced seizure activities. CaN cleavage was evident in the hippocampus 24 h after KA treatment. FK506 pretreatment blocked the truncation of CaN in the KA-treated hippocampus. Cresyl violet and TUNEL staining showed that FK506 prevented KA-induced hippocampal cell death. In particular, Western blot analysis showed that KCC2 expression was time dependent, with a peak at 6 h and a return to decreased levels at 48 h, whereas FK506 pretreatment inhibited the KA-induced decrease in KCC2 expression in the hippocampus. Immunofluorescence showed that FK506 pretreatment protected the loss of inhibitory GABAergic KCC2-expressing neurons following KA treatment. Taken together, these results provide evidence that altered KCC2 expression may be associated with Ca(2+)-mediated seizure activity and indicate that neuron-specific KCC2 may be involved in neuroprotection after seizures.</P>

Thyroid Hormone Replacement Therapy Attenuates the Decline of Renal Function in Chronic Kidney Disease Patients with Subclinical Hypothyroidism

Shin, Dong Ho,Lee, Mi Jung,Lee, Hye Sun,Oh, Hyung Jung,Ko, Kwang Il,Kim, Chan Ho,Doh, Fa Mee,Koo, Hyang Mo,Kim, Hyoung Rae,Han, Jae Hyun,Park, Jung Tak,Han, Seung Hyeok,Yoo, Tae-Hyun,Kang, Shin-Wook Mary Ann Liebert 2013 Thyroid Vol.23 No.6

Distribution of Rare Plants and Endemic Plants in Jirisan National Park

Shin, Hyun-Tak,Yi, Myung-Hoon,Yoon, Jung-Won,Yoo, Ji-Hyun,Lee, Byoung-Chun,Park, Eun-Hee national science museum of korea 2010 Journal of Korean nature Vol.3 No.4

The results of the study of the rare and regional species of the Jirisan (Mt.) Korea National Park has reported 3 CR species, including the Allium victorialis var. platyphyllum, 4 EN species, including Rhododendron tschonoskii, 7 VU species, including Cacalia pseudo-taimingasa, 11 LC species, including Lilium distichum, and 3 DD species, including Aconitum chiisanense, which makes a total of 28 species. In terms of species exclusive to the region, a total of 7 species, including Fraxinus chiisanensis, Pseudostellaria heterophylla, Filipendula formosa and Cirsium chanroenicum, were confirmed, and since they were distributed widely in the Jeonji region of Jirisan (Mt.), there was minimal damage. Since rare species are localized in the region of Agosan (Mt.), there has been continuous damage due to visitors and hikers to the area, and there seems to be the need to handle the decreasing habitat for Allium victorialis var. platyphyllum, Juniperus chinensis var. sargentii and Trientalis europaea.

A new Middle-Late Maturity rice cultivar with Excellent Grain Quality "Hopyeongbyeo"

Hyun Jung Kwang,Hyun Tak Shin,Seong Hee Lee,Jae Kil Lee,Jeong Kwon Nam,Kyu Seong Lee,Mun Sik Shin,Jae Kwon Ko,Seung Yeub Lee,Tae Hwan Noh,Jin Il Choung,Ki Young Kim,Don Hyang Choi 한국육종학회 2007 한국육종학회지 Vol.39 No.2

Hopyeongbyeo is an anther culture derived Japonica rice (Oriza sativa L.) cultivar from the cross between Hitomebore and Hwajinbyeo by the rice breeding team of Honam Agricultural Research Institute (HARI), NICS, RDA, in 2003. This cultivar has a about 126 days growth duration from transplanting to harvesting. The short and round grain shape of Hopyeongbyeo is translucent with non-glutinous endosperm. Amylose content of rice grain is about 17.8% and high palatability of cooked rice compared with Nampyeongbyeo. This cultivar shows resistant to bacterial blight pathogenes of K1. The milled rice yield of Hopyeongbyeo is about 5.13MT/ha at ordinary transplanting culture in the local adaptability test. Hopyeongbyeo would be adaptable for the southern plain area of Korea.

Distribution of Vascular Plants in the Ulleung Forest Trail Area (Seokpo to Naesujeon)

Shin, Hyun-Tak,Hwang, Jung-Hwan,Yoon, Kuk-Jin National Science Museum of Korea 2011 Journal of Korean nature Vol.4 No.2

The examination of the flora of the Sukpo-Naesujun section of the Ulleung forest trail revealed a total of 291 taxa, including 85 families, 211 genera, 246 species, 41 varieties, two forms, and two subspecies. In the area, the endangered plant species designated by the Ministry of Environment was Trillium tschonoskii, and rare or endangered plants designated by the Korea Forest Service were revealed to be 10 species, including Tsuga sieboldii, most of which were found around the trail. Campanula takesimana and Allium victorialis, in particular, are exposed to a threat of being collected for ornamental and eating purposes, respectively. The Korean endemic species in the area were 12 species including Fagus engleriana. In the area there were 50 floristic special plant species, the survey revealed 17 taxa of grade I, three taxa of grade II, nine taxa of grade III, 19 taxa of grade IV, and two taxa of grade V. Among them, Lilium hansonii and Trillium tschonoskii from grades IV and V are located near the trail, leading to concerns about damage by mountain climbers or residents. The naturalized plants in the area were a total of 18 taxa, including 6 families, 14 genera, 16 species, and one variety. Moreover, 25.4% of the overall naturalized plants in Ulleung-do appeared in the Ulleung forest trail.

Flora of vascular plants in Natural Protection Zone of Hyangro-Bong and Mt. Gyeonbong-San, Korea

Shin, Hyun-Tak,Kim, Yong-Shik national science museum of korea 2008 Journal of Korean nature Vol.1 No.1

The purpose of this study is to present rare and endangered plant species exterminated by thoughtless development and gathering after investigating the flora of vascular plants in Hyangro-Bong and Mt. Gyeonbong-San designated as the natural protection zone, and to suggest the basic data for plant resources and trees conservation. The results of the study are followed. 1. As vascular plants clarified as the result of investigation, there were total 412 groups with total 75 families, 216 genuses, 352 species, 54 varieties, and 6 forms in Hyangro-Bong. In Mt. Gyeonbong-San, there were total 356 groups with total 80 families, 207 genuses, 301 species, 46 varieties, 6 breeds, 1 hybrid, and 2 subspecies. Taken altogether, it was investigated that total 528 groups were distributed in the natural protection zone of Hyangro-Bong and Mt. Gyeonbong-San with total 83 families, 267 genuses, 448 species, 67 varieties, 10 forms, 1 hybrid and 2 subspecies. 2. With respect to the endemic plants recorded in the natural protection zone of Hyangro-Bong and Mt. Gyeonbong-San, there were total 12 groups with total 10 families, 12 genuses, 9 species, 1 variety, 1 form and 1 hybrid in the area of Mt. Gyeonbong-San. In the area of Hyangro-Bong, there were total 18 groups with total 11 families, 16 genuses, 13 species, 4 varieties and 1 form. As the result of combining two areas, there were total 23 groups with total 16 families, 21 genuses, 16 species, 4 varieties, 2 forms and 1 hybrid.3. As the Ministry of Environment's endangered wild plants recorded in this investigation, 1 species of Paeonia obovata Maxim was found. As the rare and endemic plant species designated by Forest Service, there were total 5 groups with total 5 families and 5 genuseses in the area of Mt. Gyeonbong-San. Also, there were total 13 groups with total 9 families, 12 genuses, 12 species and 1 variety in the area of Hyangro-Bong. That is, it was confirmed that total 15 groups with total 9 families, 12 genuses, 14 species and 1 variety grew in the natural protection zone of Hyangro-Bong and Mt. Gyeonbong-San. 4. As the naturalized plant classified in this investigation, there were total 18 groups with total 7 families, 13 genuses, 17 species and 1 variety in the area of Mt. Gyeonbong-San. In the area of Hyangro-Bong, there were total 19 groups with total 8 families, 15 genuses, 18 species and 1 variety. Taken altogether, total 24 groups with 9 families, 17 genuses, 23 species and 1 variety were classified. Among the area of Hyangro-Bong and Mt. Gyeonbong-San, the top part and mountainside part were perfectly destroyed because of a military road. Because of an encampment construction, repair construction and the military strategy, the mountain's top part where the alpine plants inhabit has been destroyed. Because the army's shooting range is located in the area of Mt. Gyeonbong-San, it causes a serious damage. Accordingly, it is necessary to find out various restoration and preservation plans. Also, an efficient management of the Cultural Heritage Administration and the Ministry of Defense is required.