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      • KCI등재

        정보화근로사업으로 인한 관련산업의 고용유발효과 분석 : 산업연관분석 (Input-Output Analysis)기법의 적용 An Application of the Input-Output Analysis

        박광국,주효진,최병기 한국정책학회 2002 韓國政策學會報 Vol.11 No.3

        본 연구는 정보화근로사업으로 인한 관련산업의 고용유발효과가 어느 정도인가를 알아보기 위해 산업연관분석(I/O) 기법을 적용하여 그 효과를 추정하였다. 이를 위해 1998년부터 2000년까지 한국전산원에 정보화근로사업 예산지출내역서를 보고한 7개 중앙행정기관(행정자치부. 외교통상부, 건설교통부, 보건복지부. 법제처, 대검찰청, 기상청)을 대상으로 하였으며, 정확한 추정을 위해 한국은행에서 1998년을 기준으로 작성하여 2001년 7월에 발간한 산업연관표(인장표)를 이용하였다. 산업연관분석을 위해 먼저 정보화근로사업의 예산지출내역을 정보화기반조성 예산지출부분과 인건비 지출부분으로 구분한 다음 각 부문별 예산지출내역을 산업연관표의 분류기준에 맞추어 재분류하였다. 또한 산업연관분석에 필요한 산업부문별 생산유발계수와 고용유발계수를 도출하였다. 분석결과, 정보화기반조성 예산지출로 인해 45,999명의 고용유발효과가 있었으며. 인건비 예산지출로 인해 2,020명의 고용유발효과가 있는 것으로 나타났다. 따라서 전체적으로 정보화근로사업으로 1998년부터 2000년까지 약 307억원의 예산지출을 통해 약 48.019명의 고용유발효과가 관련산업에서 발생한 것으로 추정되었다. The purpose of this study is to estimate employment induced effects produced by the IT New Deal by introducing the method of the input-output analysis. The seven central governmental agencies were sampled because they reported the whole budget data related to the IT New Deal from 1998 to 2000. For the elaborate estimate, the 「1998 Input-Output Table: Extended Version」 released by the Bank of Korea on July, 2001 was used. The analysis was conducted according to the following steps. First, the budget outlays of the IT New Deal Program were reconstructed based on the classification system of the input-output table. Second, the coefficients of production and employment induced by the industrial sector were drawn in order to estimate the whole effects resulting from the IT New Deal. The analytic results showed that employment induced effect of 45,999 persons was estimated with the budget expenditure invested in purchasing infrastructure equipments and employment induced effect of 2,020 persons was produced with the budget expenditure used in hiring manpower for the IT New Deal.

      • KCI등재

        흰쥐 생체시료 중 5-플루오로우라실 및 테가푸르의 안정성

        장지현,박종국,강진형,정석재,심창구,구효정 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.3

        5-Fluorouracil (5-FU) is an antimetabolite anticancer agent active against many types of solid tumors. Tegafur (TF), a prodrug of 5-FU, is frequently used in combination with uracil as dihydropyrimidine dehydrogenase (DPD) inhibitory fluoropyrimidine. We studied the stability of 5-FU and TF in biological fluids of rats and determined their bioavailability (BA) and excretion into bile, and urine. The drug concentrations were analyzed by an HPLC method. At room temperature, there was a 14-30% decrease in the concentration of 5-FU and TF in bile, urine, and plasma specimen at 10 and 100 μg/ml over 240 min. No significant difference was noted among the sample types or between two different concentrations of 10 and 100 μg/ml. The decrease in drug concentration was significantly less in samples kept on ice (6-12%) for both drugs. These data indicate that biological fluid samples containing 5-FU or TF in plasma, urine, or bile should be placed on ice during the sample collection. Following these storage guidelines, samples were collected after administration 50 ㎎/㎏ of each drug via i.v. or oral route. BA was 1.5 folds greater for TF (60%) than that of 5-FU (42%). Approximately 0.52 and 3.3% of the i.v. doses of 5-FU and TF was excreted into bile, respectively. Renal clearance of 5-FU was about 16% of its total body clearance. These results suggest that instability of 5-FU and TF in biological fluids should be considered in pharmacokinetic or pharmacogenomic studies.

      • KCI등재

        흰쥐의 방사선 피폭후 생물학적 지표로서의 혈액효소

        김진규,김상복,김국찬,천기정,김인규,박효국,이강석 대한방사선 방어학회 1993 방사선방어학회지 Vol.18 No.2

        생물학적 선량평가를 위한 생화학적 지표 연구로서 흰쥐 혈액내 효소활성도의 변화를 조사한 결과는 다음과 같다. 1) Alkaline phosphatase 활성도는 0.1, 0.25, 0.5, 2, 4 Gy의 방사선 조사후 24시간까지 혈액내 활성도가 증가하였고 72시간 경과시에는 대조군과 비슷한 활성도를 보였다. Creatine kinase는 2, 4 Gy 방사선 조사후 혈액내에서 활성도에서 활성도가 72시간까지 증가하였으나 0.1, 0.25Gy, 0.5 Gy 방사선 조사시에는 커다란 변화를 보이지 않았다. 2) Malate dehydrogenase 활성도는 0.1, 0.25, 0.5 Gy 방사선 조사시에는 커다란 변화가 없었으며 lactate dehydrogenase는 방사선 조사후 활성도가 감소하였다. 3) GOT의 활성도는 선량률 0.1Gy/min.로 0.1, 0.25, 0.5, 2, 4 Gy 조사후에는 어떠한 변화도 없었으며 선량률 0.5 Gy/sec.로 0.5, 1, 1.5, 2, 3, 5, 7 Gy로 조사후에는 증가현상을 보이고 있다. Acid phosphatase 활성도는 상기의 어떠한 선량에서도 나타나지 않고 있다. 잠재적으로 이러한 효소들은 방사선 피폭의 지표물질로 사용될 수 있으며 생화학적 지식과 기술을 이용한 좀더 나은 지표물질을 찾기 위하여 계속적인 조사가 필요하다. Enzyme activity changes in rat blood as biochemical indicator useful for evaluating exposure dose were experimentally studied. The experimental results obtained are as follows: 1) Alkaline phosphatase activities increased in the blood serum until 24 hours after 0.1, 0.25, 0.5, 2 and 4 Gy irradiation and its activities returned mormal condition after 72 hours of post-irradiation. Creatine kinase activities increased in the blood serum until 72 hours after 2 and 4 Gy irradiation but any significant activity changes were not detected after 0.1, 0.25 Gy irradiation. 2) Malate dehydrogenase activities did not reveal available changes changes after 0.1, 0.25, 0.5 Gy irradiation and lactate dehydrogenase activities decreased in the blood serum after 0.1, 0.25, 0.5 Gy irradiation. 3) Glutamate oxaloacetate transaminase activity changes were detected in the blood serum after 0.1, 0.25, 0.5, 2, 4 Gy(0.1 Gy/min.) and GOT activities increased after 0.5, 1, 1.5, 2, 3, 5, 7 Gy(0.5 Gy/sec.). Any acid phosphatase activities were detected in the blood serum after 0.1, 0.25, 0.5, 2, 4 Gy(0.1 Gy/min.) and 0.5, 1, 1.5, 2, 3, 5, 7 Gy(0.5 Gy/sec.) irradiation. Potentially some of these enzymes can be used as indicator protein for radiation injury. Futher investigation is needed to find better biochemical indicatiors utilizing recent knowledge and techniques of biochemistry.

      • Population Dynamics of Rice Stem Borer Under Climate Change

        Hyo seok Lee,Jong-Kook Jung,Chang-Gyu Park,Man-Young Choi,Joon-Ho Lee 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.04

        Rice stem borer, Chilo suppressalis Walker is a significant rice insect pest. A newly hatched larva bores a hole into the rice stem and feeding inside. The damage results in drying and white heads of rice. Climate change will affect pest and its host population dynamics variously. In this study, the degree of asynchrony between emergence of rice stem borer and rice transplanting was examined by their phenology models. Also, correlation was examined between winter mortalities of the rice stem borer and relative humidity categorized by daily minimum temperature in 12 sites throughout the country from 1992 to 2013. The degree of asynchrony appears to be increased in future climate condition. And we found a negative correlation between winter mortality and the relative humidity. Winter mortality will be decreased in the future because of increasing winter minimum temperature and snowfall. We hypothesize that the stem borer may increasingly harbor in alternative hosts such as reed in its first generation and move to rice in the second generation. Currently the simulation study is being conducted to verify this hypothesis.

      • SCOPUSKCI등재

        Rapid Identification of Rickettsiae using the Real-Time PCR

        Park, Hyo-Soon,Lee, Jung-Hee,Jin, Kwang-Hoon,Jang, Won-Jong,Park, Kyung-Hee,Kook, Yoon-Hoh,Lee, Seung-Hyun 대한미생물학회 2008 Journal of Bacteriology and Virology Vol.38 No.4

        In this study, new real-time PCR method based on the groEL gene was developed and investigated. Four spotted fever group (SFG) strains, four typhus group (TG) strains, and four scrub typhus group (STG) strains were easily differentiated as a distinct entity. This PCR assay was applied to detect Rickettsia DNA from 100 ticks. Twelve Haemaphysalis longicornis ticks were found positive and identified as spotted fever group Rickettsia. This real-time PCR method could simultaneously perform the rapid identification of rickettsiae and the differential diagnosis of SFG, TG, and STG in a single reaction.

      • SCOPUSKCI등재
      • KCI등재후보

        만성 특발성 변비증의 임상적 고찰

        박효진(Hyo Jin Park),이찬희(Chan Hee Lee),정준표(Jun Pyo Chung),이관식(Kwan Sik Lee),이상인(Sang In Lee),박인서(In Suh Park),손승국(Seung Kook Sohn),지훈(Hoon Ji),강성웅(Seoung Woong Kang) 대한내과학회 1994 대한내과학회지 Vol.46 No.5

        N/A Objectives: As nonorganic, or functional factors play an important etiopathogenetic role in chronic constipation, we have reviewed functional tests on patients with chronic idiopathic constipation. Results of investigation and subsequent proper treatment are suggested. Methods: Clinical assessment, colonic transit, defecogram, anorectal manometry and pelvic floor electrophysiologic tests were performed in 30 patients with chronic idiopathic constipation, Results: 1) The ratio of male to female was 1:4, and the mean age was 48.2 years. Primary complaints were incomplete evacuation (83.3%), abdominal fullness (70.0%), abdominal pain (70.0%), rectal bleeding (43.3%), nausea (33.3%), tenesmus (33.3%) and dysuria (20.0%). Hemorrhoids and melanosis coli were present in 70.4% and 11.1% of the patients respectively at colonoscopy. The types of personality using the Minnesota Multiphasic Personality Inventory showed somatization 50.0% and psycho- physiological reaction 41.7%. 2) Colonic transit studies identified three patterns: normal transit 38.9%, colonic inertia 22.2%, pelvic outlet obstruction 16.7%, and mixed type 22.2%. The mean transit time of total colon was 56.4±5.0 hr. in colonic inertia and mixed type. 3) Defecogram revealed rectocele 77.8%, incomplete evacuation 48.1%, paradoxical contraction of puborectalis 40.7%, rectal intussusception 25.9%, parietal rectal rigidity 11.1%, and excessive pelvic floor descent 11.1%. 4) The mean minimal sensory volume, anal sphincter length, maximum resting and squeeze anal pressure was 47.9±17.5 ml, 3.9±0.9 cm, 104.3±17.9mmHg and 156.4±15.0mmHg respectively. The anorectal inhibitory reflex was intact in all patients. 5) Electrophysiologic studies suggested pudendal neuropathy in 5 patients (27.8%). 6) The patients were treated by drug therapy 83.3%, biofeedback therapy 10.0% and operation 6.7%. Conclusion: From the above results, systematic diagnostic evaluation and proper treatment for the patients with chronic idiopathic constipation in view of functional motility disorder are required and treatment can be helpful particularly when directed by a multidisciplinary team approach.

      • KCI등재

        Growth and Developmental Characteristics of Lettuce, Tomato and Melon Grown under Spectrum Conversion Greenhouse Films

        Joon-Kook Kwon,Kyoung-Sub Park,Hyo-Gil Choi,Sun-Yi Lee,K. Bekhzod,Mi-Ran Hwang,Nam-Jun Kang 경상대학교 농업생명과학연구원 2013 농업생명과학연구 Vol.47 No.1

        This experiment was carried out to determine the effect of different spectrum conversion greenhouse films (red, blue, red+blue) to changing microclimate and subsequent effect on growth and quality of lettuce (Lactuca sativa L.), tomato (Solanum lycopersicum L.), and melon (Cucumis melo L.) Transmission of PAR (photosynthetic active radiation, 400-700 nm) under red, blue, and blue+red (BR) films was higher by 7.2, 7.6, and 5.8%, respectively, as compared with control greenhouse film. Light transmission in the 300-1100 nm wave band was 91.6% and 91.3% under red and blue films, respectively, compared to 86.4% under control film. Mean daytime temperature in greenhouse was slightly higher in red and blue film and mean night time temperature was higher in BR film. There were no significant differences in relative humidity among the films. Number of leaves and plant fresh weight of lettuce were higher under BR film. Total number of marketable tomato fruits was greater under blue and BR film and fruit weight was heavier under red and blue film compared to control film. Under BR and red film melon fruit weight was increased by 140 g and 80 g respectively, as compared to control film. Sugar content in melon and tomato fruits was not affected by covering films.

      • SCOPUSKCI등재

        경련성 골반상 증후군의 임상적 연구

        박효진(Hyo Jin Park),조재식(Jae Sik Cho),배희동(Hee Dong Bae),정준표(Jun Pyo Chung),이상인(Sang In Lee),박인서(In Suh Park),지훈(Hoon Ji),손승국(Seung Kook Sohn) 대한소화기학회 1994 대한소화기학회지 Vol.26 No.3

        N/A The spastic pelvic floor syndrome is a functional disorder due to abnormal contraction in- stead of relaxation of the pelvic floor muscle during straining. This inhibits defecation and gives rise to constipation. We carried out the clinical and psychologic analysis, defecogram, electrophysiologic tests, and treatment in 17 patients with spastic pelvic floor syndrome. The mean age of patients was 48.2+10.1 years. The male to female ratio was 1:7.5. Prirnary com plaints were incomplete evacuation 82.3%, constipation 52.9%, tenesmus 41.2%, straining 41.2 %, and dysuria 29.4%. The patterns of personality using the MMPI showed somatization type in 7 cases and psychophysiologic reaction type in 4 cases. Defecogram revealed paradoxical contraction of puborectalis in 100.0% of cases,incomplete evacuation 76.5%, rectocele 58.8%, incontinence 17.6%, intussusception 5.9%, and excessive pelvic floor descent 5.9%. The ano- rectal angle in patients did not increase during straining and rernained about 90. The mean maximum resting and squeezing anal canal pressures were 94.4 + 48.4mmHg, and 136.4 + 28.8 mmHg. Seven patients(70.0%) were unable to expel a balloon. The pudendal neuropathy re- vealed in 4 patients(40.0%). Seven patients underwent a EMCr-based biofeedback therapy. Four among them(57.1%) had increased bowel frequency and improved the symptom of in- complete evacuation. In conclusion, careful history taking, physical examination and colorectal motility tests perrnit diagnosis of spastic pelvic floor syndrome. This disease is related with incoordination of pelvic floor muscle, so treatment should be aimed at restoration of normal muscle function through biofeedback.(Korean J Gastroenterol 1994; 26: 482 490)

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