알콜중독자 부부집단 프로그램에 관한 연구 : For the development of a Couples Group Intervention Program for Recovery of Alcoholics(Ⅲ) 알콜중독자의 회복을 위한 부부집단 개입 프로그램 개발 연구(Ⅲ)

윤명숙,김미혜,엄예선,이은주 한국 정신보건 사회사업학회 1995 정신보건과 사회사업 Vol.2 No.-

Couple therapy has been recognized as an effective way to treat alcoholism. However, research by the authors indicate there are no couple therapy porgrams currently in the Korean psychiatric setting. The purpose of this study is to develop an effective program to aid in the recovery alcoholics and their spouses. This program is specifically designed for the couples of hospitalized alcoholics. The program consists of 10 sessions, the first four held with gender specific groups, the final five as co-joint couple sessions. The groups will meet 2 times weekly with five monthly after care follow ups. The program is divided into 3 phases ; The first phase deals with the symptoms of alcoholism and its impact on relationships with in 1st-2nd sessions. The second phase treats the issues of co-dependency and the recovery process with in 3th-4th sessions. In the final phase, conflict resolution, communication, anger control, and stress management skills are developed with in 5th-9th sessions. In the final session of the last phase, all 3 phases are integrated and summarized. At this point the group sessions are terminated, five follow up after care sessions are scheduled, to be conducted on a monthly bases. These sessions are designed to help the couple with unresolved issues, assist with implementation of their after care plan, and to monitor the couples progress with in a life of sobriety. The methods of implementing the program are centered on the cognitive behavioral approach, utilizing lectures, group discussion, role play and feedback sessions.

치매환자 조호자를 위한 교육지지프로그램의 효과성에 관한 비교연구

송 흡(Heup Song),강재명(Jae Myeong Kang),김병규(Steven B. Kim),조성진(Seong Jin Cho),윤선경(Seon kyung Yun),윤혜진(Hye jin Yoon),연병길(Byeong Kil Yeon) 대한노인정신의학회 2017 노인정신의학 Vol.21 No.1

Objective:We studied the effect of Hyu-Sig-Gong-Gan and Hye-Ah-Rim on several evaluations and compared the two programs. We then investigated factors associated with the difference between pre- and post-ratings. Methods:Thirty-six patients were randomized to Hyu-Sig-Gong-Gan (n=23) or Hye-Ah-Rim (n=13). We tested for the effect of each program on several evaluations and compared the two programs through Zarit Burden Interview (ZBI), Center for Epidemiologic Studies-Depression Scale, Dementia Attitude Scale (DAS)-intelligence, DAS-comfort and DAS-total. We then investigated whether the difference between pre- and post-rating depends on other factors. Results:We observed significant positive effect of Hyu-Sig-Gong-Gan on DAS-comfort (t=1.843, p=0.039) and significant positive effect of Hye-Ah-Rim on ZBI (t=-2.327, p=0.019), DAS-comfort (t=2.241, p=0.022), and EuroQol-5 Dimensions-Visual Analogue Scale (t=2.537, p=0.013). For comparing the two programs, we found a lack of evidence for the difference in any of the five commonly observed evaluations. In the secondary analysis, we observed a strong trend that the two programs were particularly effective for caregivers with negative pre-ratings. Conclusion:The two programs showed positive effects on the various evaluations, but some evaluations could not reach statistical significance. The programs appear to be particularly helpful for those who are in need before the program participation.

젊은 성인 남자의 흡연과 혈청 지질과의 관련성

조선,류소연,박종,강명근,김은숙,김형철,박광희,윤혜은,노희송 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Objectives: This study was performed to find the association of cigarette smoking and blood lipid profiles in healthy young adults. Methods: The data was collected by a self-administered questionnaire and health examination in 489 professional soldiers from 6 to 12 May, 2004. The status of cigarette smoking was classified by non-smoking, ex-smoked, ≤4.9, 5-9.9, and ≥10 pack-years. The statistical analysis were used by chi-square test, analysis of variance and analysis of covariates. Results: In status of subjects cigarette smoking, current smoking, ex-smoked, and non-smoking were 71.8%, 11.2%, and 17.0%, respectively, In distribution by amount of smoking, non-smoking, ex-smoked, ≤4.9 pack-years, 5-9.9 pack-years, and ≥10 pack-years were 17.0%, 11.2%, 37.4%, 21.3%, and 13.1%, respectively. At other confounding variables were controlled, total cholesterol and LDL-cholesterol were increased significantly when amount of smoking was increased. However, triglyceride and HDL-cholesterol did not showed statistically significant differences, Conclusion: Smoking has relevant to total cholesterol and LDL-cholesterol and it is need to perform the further study for finding how blood lipid profiles are affected its level by cigarette smoking and to find an influence of cigarette smoking on cardiovascular disease.

UV-TiO₂광촉매 반응기를 이용한 미생물의 살균효과

김시욱,이정섭,정해광,박열,윤성명,유진철,이범규,이인화,박진열 조선대학교 환경공해연구소 1998 環境公害硏究 Vol.14 No.-

UV-TiO_(2) 반응기를 이용하여 Escherichia coli와 Aspergillus oryzae var. oryzae의 살균효과를 측정하였다. 254 ㎚에서 최대 14 watt의 자외선 방출량을 내는 램프를 원형 Pyrex유리관 중앙에 설치하였고 TiO_(2)는 석영관에 박막증착(Thin Film Coating)된 형태와 슬러리 형태로 나누어 회분식으로 살균정도를 측정하였다. E. coli에 대한 살균력은 1.7× 10^(7) cells/㎖에 대해 5분간 자외선 조사를 하였을 경우 2.0× 10^(2) cells/㎖으로 감소하였고, 자외선 조사와 함께 슬러리 형태의 TiO_(2)를 첨가하였을 경우에는 3.4× 10 cells/㎖으로, 자외선 조사와 함께 TiO_(2)가 석영관에 박막증착된 경우에는 7.6× 10^(2) cells/㎖으로 감소하였다. 한편 위와 같은 조건에 유리관 하부에서 기포를 주입후 11분 동안 자외선을 조사시킨 경우에는 1.3× 10^(2) cells/㎖으로, 자외선 조사와 함께 슬러리 형태의 TiO_(2)를 첨가하였을 경우에는 1× 100 cells/㎖으로, 자외선 조사와 함께 TiO_(2)가 박막증착된 경우에는 7.9× 10 cells/㎖을 나타내었다. 결국 UV-TiO_(2) 반응기에 사용되는 TiO_(2)가 슬러리 형태일 때 최대 살균효과를 나타내었으나 기포가 첨가되었을때는 오히려 살균에 장애를 받는 것으로 나타난 반면 석영관에 박막증착된 경우에는 기포가 첨가되는 것이 살균에 효과적인 것으로 관찰되었다. The killing effect of UV-TiO_(2) photocatalytic system on the Escherichia coli DH5-慣 and Aspergillus oryzae var. oryzae (KCTC 6095) was studied. The UV lamp which emits maximum 14 watts at 254 nm was set on the center of pyrex round glass tube. Two types of TiO_(2), one of which is slurry and another which is thin film coated form, were used to determine the killing effect. When UV was irradiated to 1.7 * 10^(5) cells/??of E. coli for 11 min, the living cell number decreased to 4.0 * 1.0^(0) cells/?? The effect of UV system together with slurried TiO_(2) was less than 1 cells/?? whereas that of UV-coated TiO_(2) system decreased to 7.1 * 10^(3) cells/?? To study the effect of bubble on the killing of microorganisms, air was bubbled to the bottom of glass tube. When 1.7 * 10^(5) cells/??were exposed to UV for 11 min in combination with air bubble, the living cell number decreased to 1.3 x 10^(2) cells/?? In the same condition except the addition of slurried TiO_(2), the living cells were 1 * 10^(2) cells/?? However, more cells could be killed by the system which consists of UV, coated TiO_(2), and air bubble (7.9 * 10^(1) cells/??. From these results, it was found that UV-slurried system is the most effective one, but its killing effect is not stimulated by air bubble. However, bubbling was very effective in the UV-coated TiO_(2) system.

UV-TiO_2 광촉매 반응기를 이용한 미생물의 살균효과

김시욱,이정섭,정혜광,박열,윤성명,유진철,이범규,이인화,박진열 조선대학교 환경연구소 1998 環境硏究 Vol.14 No.1

UV-TiO_2 반응기를 이용하여 Escherichia coli와 Aspergillus oryzae var. oryzae의 살균효과를 측정하였다. 254㎚에서 최대 14 watt의 자외선 방출량을 내는 램프를 원형 Pyrex유리관 중앙에 설치하였고 TiO_2는 석영관에 박막증착(Thin Film Coating)된 형태와 슬러리 형태로 나누어 회분식으로 살균정도를 측정하였다. E. coli에 대한 살균력은 1.7×10^7 cells/㎖에 대해 5분간 자외선 조사를 하였을 경우 2.0×10^2 cells/㎖으로 감소하였고, 자외선 조사와 함께 슬러리 형태의 TiO_2를 첨가하였을 경우에는 3.4×10 cells/㎖으로, 자외선 조사와 함께 TiO_2가 석영관에 박막증착된 경우에는 7.6×10^2 cells/㎖으로 감소하였다. 한편 위와 같은 조건에 유리관 하부에서 기포를 주입수 11분 동안 자외선을 조사시킨 경우에는 1.3×10^2 cells/㎖으로, 자외선 조사와 함께 슬러리 형태의 TiO_2를 첨가하였을 경우에는 1×102 cells/㎖으로, 자외선 조사와 함께 TiO_2가 박막증착된 경우에는 7.9×10 cells/㎖을 나타내었다. 결국 UV-TiO_2 반응기에 사용되는 TiO_2가 슬러리 형태일 때 최대 살균효과를 나타내었으나 기포가 첨가되었을때는 오히려 살균에 장애를 받는 것으로 나타난 반면 석영관에 박막증착된 경우에는 기포가 첨가되는 것이 살균에 효과적인 것으로 관찰되었다. The killing effect of UV-TiO_2 photocatalytic system on the Escherichia coli DH5-α and Aspergillus oryzae var. oryzae (KCTC 6095) was studied. The UV lamp which emits maximum 14 watts at 254 ㎚ was set on the center of pyrex round glass tube. Two types of TiO_2, one of which is slurry and another which is thin film coated form, were used to determine the killing effect. When UV was irradiated to 1.7×10^5 cells/㎖ of E. coli for 11 min, the living cell number decreased to 4.0×10^0 cells/㎖. The effect of UV system together with slurried TiO_2 was less than 1 cells/㎖, whereas that of UV-coated TiO_2 system decreased to 7.1×10^3 cells/㎖. To study the effect of bubble on the killing of microorganisms, air was bubbled to the bottom of glass tube. When 1.7×10^5 cells/㎖ were exposed to UV for 11 min in combination with air bubble, the living cell number decreased to 1.3×10^2 cells/㎖. In the same condition except the addition of slurried TiO_2, the living cells were 1×10^2 cells/㎖. However, more cells could be killed by the system which consists of UV, coated TiO_2, and air bubble (7.9×10^1 cells/㎖). From these results, it was found that UV-slurried system is the most effective one, but its killing effect is not stimulated by air bubble. However, bubbling was very effective in the UV-coated TiO_2 system.

토양 미생물인 Streptomyces tubercidicus에서 분리한 GTPcyclohydrolase Ⅰ 저해제

한지만,김시욱,이인화,박열,정혜광,윤성명,유진철 조선대학교 약학연구소 1998 藥學硏究誌 Vol.19 No.1

GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphates and formic acid. and thus performs the first committing step in the biosynthesis of the pteridine moiety of folk acid in microorganisms and of tetrahydrobiopterin in higher animals. GTP cyclohydrolase I isolated from Streptomyces tubercidicus was inhibited by DL-6-methyl-5,6,7,8-tetrahydropterin and xanthopterin, and was not inhibited by tetrahydrofolic acid, pterin, pterin-6-carboxylic acid, biopterin, neopterin, ribofravin. These results suggest that bacterial GTP cyclohydrolase I may be regulated by its metaboilic end product.

Immunomodulatory and anti-inflammatory effects of the extract of root bark from Asparagus cochinchinensis on acute and chronic skin inflammation

Hye Won Lee,Sung Wook Chae,Ho Kyoung Kim,Myeong Sook Cheon,Do Yeon Lee,Tae Sook Yoon,Byeong Cheol Moon,Byung Kil Choo,A Yeong Lee,Yun Ui Ji,Goya Choi 한국육종학회 2007 한국육종학회 학술발표회 발표요지 Vol.2007 No.6

A Study on the Content of Vitamins in Fortified Food

Myeong-Gil Kim,Young-Sug Kim,Young-Su Kim,Seong-Bong Lee,Kyong-Shin Ryu,Mi-Hye Yoon,Jong-Bok Lee 한국식품영양과학회 2014 한국식품영양과학회 학술대회발표집 Vol.2014 No.10

Prevalence, Serotype Diversity, Genotype and Antibiotic Resistance of Listeria monocytogenes Isolated from Carcasses and Human in Korea

Hye-min Oh,Se-jeong Kim,Soo-min Lee,Hee-young Lee,Ji-myeong Ha,Jee-yeon Lee,Yu-kyung Choi,Kyoung-Hee Choi,Yo-han Yoon 한국축산식품학회 2018 한국축산식품학회지 Vol.38 No.5

This study investigated the prevalence of Listeria monocytogenes in slaughterhouses, and determined serovars and genotypes, and antibiotic resistance of the isolates obtained from slaughterhouses and humans in Korea. Two hundred ninety samples were collected from feces (n=136), carcasses [n=140 (cattle: n=61, swine: n=79)], and washing water (n=14) in nine slaughterhouses. Eleven human isolates were obtained from hospitals and the Korea Center for Disease Control and Prevention. Listeria monocytogenes was enriched and identified, using polymerase chain reaction (PCR) and 16S rRNA sequencing. Serovars and presence of virulence genes were determined, and genetic correlations among the isolates were evaluated by the restriction digest patterns of AscI. Antibiotic resistance of L. monocytogenes isolates were examined against 12 different antibiotics. Of 290 slaughterhouse samples, 15 (5.17%) carcass samples were L. monocytogenes positive. Most L. monocytogenes isolates possessed all the virulence genes, while polymorphisms in the actA gene were found between carcass and human isolates. Serovars 1/2a (33.3%) and 1/2b (46.7%) were the most frequent in carcass isolates. Genetic correlations among the isolates from carcass and clinical isolates were grouped within serotypes, but there were low geographical correlations. Most L.monocytogenes isolates were antibiotic resistant, and some strains showed resistance to more than four antibiotics. These results indicate that L. monocytogenes are isolated from carcass and human in Korea, and they showed high risk serotypes and antibiotic resistance. Therefore, intensive attentions are necessary to be aware for the risk of L.monocytogenes in Korea.

조간대 저서무척추동물 군집에 미치는 태안화력발전소 온배수의 영향

윤성명,정석훈,백경환,김시욱,정혜광,이정섭 조선대학교 부설생명과학 연구소 1999 생명과학 연구 Vol.7 No.-

태안화력발전소의 온배수 유출이 주변 해역 조간대의 저서무척추동물 군집에 미치는 영향을 파악하기 위한 조사가 1998년에 수행되었다. 현지조사는 발전소 주변 조간대의 배수구 정점과 대조정점인 취수구 정점의 2곳에서 계절별로 진행되었다. 출현종수 및 출현종 구성과 생물량 분포, 다양도지수의 측면에서 분석한 결과 배수구 정점의 조간대 저서무척추 동물 군집은 대조정점의 군집과 뚜렷한 차이를 나타내지 않았다. 생물량의 면에서는 배수구 정점의 군집 생물량이 대체적으로 대조정점 군집의 생물량보다 많은 결과를 보였는데, 이러한 것은 특히 겨울철 조사에서 뚜렷하였다. 본 연구의 결과는 조사지역 발전소의 온배수가 조간대 저서무척추동물 군집에 미치는 부정적 영향은 거의 없으며, 오히려 해수온도를 높여 군집의 생물량 증가에 기여하고 있음을 시사하고 있다. The effects of heating overflow produced from the Taean Thermoelectric Power Plant on the intertidal invertebrate community in the adjacent sea to were studied in 1998. The invertebrate community of the station near the waterway showed no remarkable differences compared with that of control station in the respect of the number of species, species composition, biomass distribution, and diversity index. Heating overflow of the power plant had a tendency to effect positively on the increase of intertidal invertebrate biomass, especially in winter season. These results suggest that the heating overflow of the power plant nearly does not effect negatively on the intertidal invertebrate community in the study area. On the contrary, it may effect positively on the invertebrate community in increasing the biomass by promoting the growth of organisms.