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      • A GPU-based Two Dimensional Flood Simulation System

        Kuo-Chan Hung,Chih-Yung Feng,Kun-Huai Cheng,Pei-Cheng Tsao1,Hung-Kwai Chen 한국방재학회 2016 Journal of Disaster Management Vol.1 No.1

        Abstract A GPU-based flood simulation system is developed in this research. The system comprises two main components: a GPU-lized two bdimensional flood simulation model named GLMRT and a web-GIS user interface. GLMRT is designed and constructed with following features. First, GLMRT is constructed based on Lattice Boltzmann method(LBM) and two dimensional shallow water equations. Second, GLMRT is combined with sink/source terms including excess rainfall and pump-like drainage. Third, a dry-wet boundary determining mechanism is considered in GLMRT. Fourth, real DEM data can be used in simulating water movement on the land surface. Finally, GPU accelerated technique is integrated into GLMRT to overcome the issue of time cost in calculation. The web-GIS based user interface is built based on cloud platform to assist data flow organization and real time simulation. The interface integrates real DEM data and receives precipitation estimation products from the Taiwan Typhoon and Flood Research Institute(TTFRI) and Central Weather Bureau(CWB). The simulation results would be displayed on the web-GIS via file and database transfer. Besides, a real time rendering technique based on real time simulation is developed, too. The real time rendering technique displays the simulation results via memory on GPU device and eliminates the time cost in data output. GLMRT solves a 800-second simulation of Zengwen Reservoir virtual dam break with 2,046x1,525 DEM grids (40 m resolution) within 140.11 seconds on the NVIDIA Tesla K20c. Compare to the 60,919 seconds computation time on the Intel?? Xeon?? CPU X5650 2.66GHz, the GLMRT gets a speedup of 438x. On the other hand, using GLMRT alone to simulate a 12-hour rainfall duration induced inundation would spend about 1.2 hours, which can provide buffer time for the requirement of flood prevention operation. Abstract A GPU-based flood simulation system is developed in this research. The system comprises two main components: a GPU-lized two bdimensional flood simulation model named GLMRT and a web-GIS user interface. GLMRT is designed and constructed with following features. First, GLMRT is constructed based on Lattice Boltzmann method(LBM) and two dimensional shallow water equations. Second, GLMRT is combined with sink/source terms including excess rainfall and pump-like drainage. Third, a dry-wet boundary determining mechanism is considered in GLMRT. Fourth, real DEM data can be used in simulating water movement on the land surface. Finally, GPU accelerated technique is integrated into GLMRT to overcome the issue of time cost in calculation. The web-GIS based user interface is built based on cloud platform to assist data flow organization and real time simulation. The interface integrates real DEM data and receives precipitation estimation products from the Taiwan Typhoon and Flood Research Institute(TTFRI) and Central Weather Bureau(CWB). The simulation results would be displayed on the web-GIS via file and database transfer. Besides, a real time rendering technique based on real time simulation is developed, too. The real time rendering technique displays the simulation results via memory on GPU device and eliminates the time cost in data output. GLMRT solves a 800-second simulation of Zengwen Reservoir virtual dam break with 2,046x1,525 DEM grids (40 m resolution) within 140.11 seconds on the NVIDIA Tesla K20c. Compare to the 60,919 seconds computation time on the Intel?? Xeon?? CPU X5650 2.66GHz, the GLMRT gets a speedup of 438x. On the other hand, using GLMRT alone to simulate a 12-hour rainfall duration induced inundation would spend about 1.2 hours, which can provide buffer time for the requirement of flood prevention operation.

      • SCIESCOPUSKCI등재

        The Effect of Agomelatine in Behavioral and Psychological Symptoms of Dementia

        Carol Sheei-Meei Wang(Carol Sheei-Meei Wang ),Kuo-Sheng Cheng(Kuo-Sheng Cheng),Chia-Hung Tang(Chia-Hung Tang),Ming-Chyi Pai(Ming-Chyi Pai),Pai-Lien Chen(Pai-Lien Chen),Pei-Fang Chien(Pei-Fang Chien) 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.4

        Objective: Moderate and severe behavioral and psychological symptoms of dementia (BPSD) often need medical treatment to improve symptoms. Agomelatine is a selective melatonergic (MT1/MT2) agonist that has normalizing effects on disturbed circadian rhythms and disrupted sleep−wake cycles. Its activity of 5HT-2C receptor antagonism is associated with lessening depression and anxiety and increasing slow-wave sleep. Based on past clinical records and current findings it suggests that agomelatine can improve BPSD for patients. This retrospective cohort study was designed to compare the BPSD before and after using agomelatine. Methods: Records of dementia cases who had ever received agomelatine treatment for BPSD in a general hospital setting during the past 2.5 years were identified and reviewed. Scores from before and after 3 months of treatment with agomelatine were collected for Neuropsychiatric Inventory (NPI), Brief Psychiatric Rating Scale (BPRS), and Clinical Global Impression (CGI) to compare and analyze the difference of psychological and behavioral symptoms pre- and post-agomelatine used. Results: Records of 144 cases of dementia with BPSD who had ever used agomelatine from January 2015 to June 2017 were collected. All of the 112 cases had BPRS and CGI scores, of which 75 cases had additional NPI scores. Among these 112 cases, the BPRS and CGI scores were significantly improved in all types of dementia. NPI scores indicated that the use of agomelatine alleviated obvious symptoms and decreased overall distress, especially in the depression/poor mood, anxiety, and sleep/night behavior. Conclusion: It is consistent with an effective result of agomelatine in improving BPSD.

      • SCIESCOPUSKCI등재

        A Single-Stage LED Tube Lamp Driver with Input-Current Shaping for Energy-Efficient Indoor Lighting Applications

        Cheng, Chun-An,Chang, Chien-Hsuan,Cheng, Hung-Liang,Chung, Tsung-Yuan,Tseng, Ching-Hsien,Tseng, Kuo-Ching The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.4

        This study proposes a single-stage light-emitting diode (LED) tube lamp driver with input-current shaping for T8/T10-type fluorescent lamp replacements. The proposed AC-DC LED driver integrates a dual-boost converter with coupled inductors and a half-bridge series-resonant converter with a bridge rectifier into a single-stage power conversion topology. This paper presents the operational principles and design considerations for one T8-type 18 W-rated LED tube lamp with line input voltages ranging from 100 V rms to 120 V rms. Experimental results for the prototype driver show that the highest power factor (PF = 0.988), lowest input current total harmonic distortion (THD = 7.22%), and highest circuit efficiency (η = 92.42%) are obtained at an input voltage of 120 V. Hence, the proposed driver is feasible for use in energy-efficient indoor lighting applications.

      • KCI등재후보

        MR Imaging of Pregnancy Luteoma: a Case Report and Correlation with the Clinical Features

        Hung-Wen Kao,Ching-Jiunn Wu,Kuo-Teng Chung,Sheng-Ru Wang,Cheng-Yu Chen 대한영상의학회 2005 Korean Journal of Radiology Vol.6 No.1

        We report here on a 26-year-old pregnant female who developed hirsutism and virilization during her third trimester along with a significantly elevated serum testosterone level. Abdominal US and MR imaging studies were performed, and they showed unique imaging features that may suggest the diagnosis of pregnancy luteoma in the clinical context. After the delivery, the serum testosterone level continued to decrease, and it returned to normal three weeks postpartum. The follow-up imaging findings were closely correlated with the clinical presentation.

      • KCI등재

        The energy band alignment at the interface between mechanically exfoliated few-layer NiPS3 nanosheets and ZnO

        Cheng-Tai Kuo,Karuppannan Balamurugan,Hung Wei Shiu,Hyun Ju Park,Soobin Sinn,Michael Neumann,한문섭,장영준,Chia-Hao Chen,Hyeong-Do Kim,박제근,Tae Won Noh 한국물리학회 2016 Current Applied Physics Vol.16 No.3

        We have studied the electronic structure and interfacial properties of mechanically exfoliated few-layer NiPS3 van der Waals crystals on ZnO/Nb:SrTiO3 substrates using scanning photoelectron microscopy and spectroscopy. The conducting ZnO layer enhances the visibility of few-layer NiPS3 on Nb:SrTiO3 and prevents charging effects in photoemission. We experimentally determined a type-II band alignment at the NiPS3/ZnO interface. The valence band offset (VBO) of few-layer NiPS3/ZnO is 2.8 ± 0.09 eV, and the conduction band offset is 1.0 ± 0.09 eV. Moreover, we found an increase of ~0.3 eV in VBO as decreasing NiPS3 thickness, suggesting electronic coupling or charge transfer at the NiPS3/ZnO interface.

      • KCI등재

        Knock-out of Glucose Dehydrogenase Gene in Gluconacetobacter xylinus for Bacterial Cellulose Production Enhancement

        Chia-Hung Kuo,Hsin-Yin Teng,Cheng-Kang Lee 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.1

        Glucose dehydrogenase (GDH) locates in thecytoplasmic membrane of Gluconacetobacter xylinus oxidizesglucose to gluconic acid that decreases the conversion ofglucose to bacterial cellulose (BC). In this study, a mutantof G. xylinus was generated by knocking-out the membranebound GDH gene via homologous recombination of adefect GDH gene. The production of BC by G. xylinusmutant (GDH-KO strain) using glucose as a carbon sourcewas investigated. Without the membrane bound GDHactivity, the mutant strain still produces BC and increasesglucose utilization efficiency for cellulose biosynthesis. Incontrast, the wild-type strain oxidized a large fraction ofglucose to gluconic acid that decreased the conversionyield of glucose to BC. Our results showed that the BCproduction from GDH-KO strain was about 40 and 230%higher than that of wild-type strain in static and shakenculture, respectively.

      • KCI등재

        Anterior Cervical Discectomy and Fusion for Hirayama Disease: A Case Report and Literature Review

        Yi-Hsuan Kuo,Chao-Hung Kuo,Wen-Cheng Huang,Jau-Ching Wu 대한척추신경외과학회 2019 Neurospine Vol.16 No.3

        Hirayama disease, a juvenile muscular atrophy of the distal upper extremity, is a rare form of cervical flexion myelopathy characterized by insidiously progressive weakness of the hands and forearm muscles (i.e., painless amyotrophy). The pathognomonic finding is a markedly forward-shifted spinal cord during neck flexion, demonstrated by dynamic magnetic resonance imaging (MRI), as in a young man with muscle atrophy in the bilateral distal upper extremities. In this report, the authors describe a 31-year-old man who had the classic radiological and clinical presentations of Hirayama disease. Since prior medical treatment had been ineffective for years, he underwent multilevel instrumented anterior cervical discectomy and fusion (ACDF) to keep his subaxial cervical spine slightly-lordotic (nonflexion). His motor evoked potential amplitude improved immediately during the operation, and there were improvements of myelopathy and a modest reversal of muscle wasting at 1 year postoperatively. Postoperative dynamic cervical spine MRI also demonstrated minimal cord compression and elimination of the venous plexus engorgement dorsal to the thecal sac. Although Hirayama disease is benign in nature and frequently self-limiting, multilevel instrumented ACDF could be a reasonable management option.

      • KCI등재

        A Single-Stage LED Tube Lamp Driver with Input-Current Shaping for Energy-Efficient Indoor Lighting Applications

        Chun-An Cheng,Chien-Hsuan Chang,Hung-Liang Cheng,Tsung-Yuan Chung,Ching-Hsien Tseng,Kuo-Ching Tseng 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.4

        This study proposes a single-stage light-emitting diode (LED) tube lamp driver with input-current shaping for T8/T10-type fluorescent lamp replacements. The proposed AC–DC LED driver integrates a dual-boost converter with coupled inductors and a half-bridge series-resonant converter with a bridge rectifier into a single-stage power conversion topology. This paper presents the operational principles and design considerations for one T8-type 18 W-rated LED tube lamp with line input voltages ranging from 100 V rms to 120 V rms. Experimental results for the prototype driver show that the highest power factor (PF = 0.988), lowest input current total harmonic distortion (THD = 7.22%), and highest circuit efficiency (η = 92.42%) are obtained at an input voltage of 120 V. Hence, the proposed driver is feasible for use in energy-efficient indoor lighting applications.

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