Financial Leasing Decision-making and Pricing Method for Highway Project

Hong Zhang,Dingyou Lei,Qiongfang Zeng,Yinggui Zhang 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.8

Reasonable financial leasing decision-making and pricing mechanism is the key for highway project that requires large amount of construction funds, and after-sales leaseback financial leasing mode can be well applied in financial leasing business of highway project. Based on financial real option theory, we put forward both financial leasing valuation model and binary tree option pricing model in the paper. Firstly, we analyzed real option value of financial leasing. Then, financial leasing decision-making and pricing model for highway project was built, and financial leasing decision-making and pricing method for highway project was further proposed. These models put forward in the paper can provide theoretical support for financial leasing decision-making and pricing for highway project.

A novel recyclable nano-adsorbent for enhanced oil recovery with efficient removal of Ca2+ and Cr6+ from oilfield wastewater

Lei He,Yong Dai,Zhe Wang,Lutao Yang,Luxia Zhang,Pengpeng Hu,Yutian Lei,Hong Mo,Haomiao Zhu,Jun Zhang 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.8

Oilfield wastewater has a significantly negative influence on the recovery efficiency due to its hypersalinity. Therefore, magnetic graphene oxide (GO) modified with ethylene diamine tetraacetic acid (EDTA) and grafted bypolyethylene glycol (PEG) nano-adsorbent was prepared to remove the Ca2+ and Cr6+ in Jidong Oilfield wastewaterspecifically. It was noteworthy that PEG-g-EDTA/Fe3O4/GO nano-adsorbent had excellent adsorption performance,with removal ratios up to 71.6% for Ca2+ and 42.7% for Cr6+ at 30 min. After the fifth recycling run, the nano-adsorbentstill remained with high removal ratios (69.3% for Ca2+ and 30.5% for Cr6+) and high reuse rates (89.4% for Ca2+and 95.2% for Cr6+), indicating that the nano-adsorbent had outstanding adsorption-desorption efficacy and high reusability. The adsorption test results demonstrated that the total salinity of the treated oilfield wastewater decreased byabout 5,000 ppm, and the displacement efficiency further increased by 12.5% by chemical flooding compared with theuntreated wastewater. Therefore, PEG-g-EDTA/Fe3O4/GO nano-adsorbent is an adsorbent with excellent potentialwhich can effectively remove Ca2+ and Cr6+ in oilfield wastewater to enhance oil recovery (EOR).

MiR-886-5p Inhibition Inhibits Growth and Induces Apoptosis of MCF7 Cells

Zhang, Lei-Lei,Wu, Jiang,Liu, Qiang,Zhang, Yan,Sun, Zhu-Lei,Jing, Hong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

Background and Aims: To explore the molecular mechanisms of miR-886-5p in breast cancer., we examined roles in inhibiting growth and migration of MCF-7 cells. Methods: MiR-886-5p mimics and inhibitors were used to express or inhibit MiR-886-5p, respectively, and MTT and clone formation assays were used to determine the survival and proliferation. Hoechst 33342/ PI double staining was applied to detect apoptosis. The expression of caspase-3, caspase-8, caspase-9, MT1-MMP, VEGF-C and VEGF-D was detected by Western blotting, and the levels of MMP2 and MMP9 secreted from MCF-7 cells were assessed by ELISA. MCF-7 cell migration was determined by wound healing and Transwell assays. Results: We found that the growth of MCF-7 cells was inhibited upon decreasing miR-886-5p levels. Inhibiting miR-866-5p also significantly induced apoptosis and decreased the migratory capacity of these cells. The expression of VEGF-C, VEGF-D, MT1-MMP, MMP2, and MMP9 was also found to be decreased as compared to controls. Conclusions: Our data show that downregulation of miR-886-5p expression in MCF-7 cells could significantly inhibit cell growth and migration. This might imply that inhibiting miR-886-5p could be a therapeutic strategy in breast cancer.

Dynamic Behavioral Portfolio Based on the Market Evolution

Hong-lei Zhang,Yi-xiang Tian,Li Li 보안공학연구지원센터 2015 International Journal of u- and e- Service, Scienc Vol.8 No.8

Portfolio is the core issue of financial investment. This article discusses the dynamic behavioral portfolio in an evolutionary perspective. This paper first give the market selection equation as a measure of the investor market evolution level to replace the mental account of investors return, considering the impacts of heterogeneous investors to the asset return, this paper establish an adaptation GARCH model to express the dynamic evolution of asset return and risk. And considering the non-linear relationship among assets, this paper chose Clayton Copula function to put the risk of each asset into a single unified security mental account, and establish the VaR model to control investment risk and obtained the optimal weights of behavioral portfolio in each investing period. Last this paper implemented the model of the dynamic behavioral portfolio based on the market evolution in the historical data, and gave the comparison results of the dynamic behavioral portfolio based on the market evolution, to the mean-variance model and the minimum variance model. Empirical result shows that the dynamic behavioral portfolio based on the Market Evolution has a very good investment effects.

Optimization of Cutting Parameters for Minimizing Environmental Impact: Considering Energy Efficiency, Noise Emission and Economic Dimension

Lei Zhang,Beikun Zhang,Hong Bao,Haihong Huang 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.4

Green manufacturing is attracting significant attention from the academic and industrial world under current environmental circumstances. The purpose of the present study is to evaluate trade-offs between the main factors in green manufacturing: energy, noise and cost, through cutting parameter optimization. First, the energy consumption model is developed based on the analysis of the relationship among sub-processes, power and cutting parameters. Then numerical noise emission model, which integrates orthogonal experiment and response surface method, is proposed. Moreover, Analysis of Variance results are employed to analyze the influence of cutting parameters on noise, the results show that the depth of cut is the dominating influencing factor of noise, then the cutting cost model is presented. The multi-objective optimization model for energy saving, noise reducing and cost saving is proposed, which takes cutting speed, feed fate and depth of cut as decision variables. NSGA-II is adopted to obtain the Pareto optimal solutions. The most suitable Pareto-optimal solution is selected by a combination weighting method. A case study involving the cutting process of a CNC lathe is used to validate the proposed methodology, and the results are discussed and analyzed.

Anomalous magnetization jumps in granular Pb superconducting films

Zhang An-Lei,Jiang Wan-Yan,Chen Xing-Hong,Zhang Xiao-Ke,Lu Wen-Lai,Chen Fei,Feng Zhen-Jie,Cao Shi-Xun,Zhang Jin-Cang,Ge Jun-Yi 한국물리학회 2022 Current Applied Physics Vol.35 No.-

In granular superconductors, the grain boundaries are closely related to the vortex dynamics and the macroscopic superconducting properties. In our research, Pb films with different grain sizes were prepared by tuning the substrate temperature. With the grain size decreasing, Pb films are prone to feature the anomalous magnetization jumps in the M − T curves, while in the M − H curves flux avalanche happens. Both phenomena appear in the same region of the H − T phase diagram and thus are considered to have the same origin. The further theoretical analysis shows that with grain size decreasing the pinning mechanism evolves from a mixed δTc and δl pinning to the δl pinning mechanism. The results shed light on the study of pinning mechanism for granular superconductors and is beneficial to the potential application of manipulating vortex pinning by regulation of intrinsic defects.

Melatonin Attenuates Noise Stress-induced Gastrointestinal Motility Disorder and Gastric Stress Ulcer: Role of Gastrointestinal Hormones and Oxidative Stress in Rats

( Lei Zhang ),( Ji T Gong ),( Hu Q Zhang ),( Quan H Song ),( Guang H Xu ),( Lei Cai ),( Xiao D Tang ),( Hai F Zhang ),( Fang E Liu ),( Zhan S Jia ),( Hong W Zhang ) 대한소화기기능성질환·운동학회 2015 Journal of Neurogastroenterology and Motility (JNM Vol.21 No.2

Background/Aims There are increasing evidences for gastrointestinal motility disorder (GIMD) and gastric stress ulcer induced by noise stress. The present study was to investigate the reversed effect of melatonin on GIMD and gastric stress ulcer induced by noise stress and potential mechanism. Methods Noise stress was induced on rats, and melatonin (15 mg/kg) was administered to rats by intraperitoneal injection. Differences were assessed in gastric residual rate (GRR), small intestine propulsion rate (SPR), Guth injury score, cortisol, gastrointestinal hormones (calcitonin-gene-related peptide and motilin) and oxidative stress markers (superoxide dismutase and malondialde hyde) in blood plasma as well as gastric mucosa homogenate with or without melatonin. The pathological examination of gastric mucosa was also performed. Results The GRR and SPR were improved by noise stress compared with control (P < 0.05). The pathological examination and Guth injury score revealed gastric stress ulcer. Moreover, the levels of cortisol, motilin and malondialdehyde in blood plasma and malondialdehyde in gastric mucosa homogenate were increased by noise stress (P < 0.05). CGRP and superoxide dismutase activity in both of blood plasma and gastric mucosa homogenate were significantly decreased (P< 0.05). Furthermore, melatonin reversed changes in GRR, SPR, pathological examination, Guth injury score, cortisol, motilin, CGRP, superoxide dismutase activity and malondialdehyde (P < 0.05). Conclusions Melatonin is effective in reversing the GIMD and gastric stress ulcer induced by noise stress. The underlying mechanism may be involved in oxidative stress and gastrointestinal hormones. (J Neurogastroenterol Motil 2015;21:189-199)

Myeloid-Derived Suppressor Cells Are Associated with Viral Persistence and Downregulation of TCRζ Chain Expression on CD8+ T Cells in Chronic Hepatitis C Patients

Qing-Lei Zeng,Bin Yang,Hong-Qi Sun,Guo-Hua Feng,Lei Jin,Zheng-Sheng Zou,Zheng Zhang,Ji-Yuan Zhang,Fu-Sheng Wang 한국분자세포생물학회 2014 Molecules and cells Vol.37 No.1

Myeloid-derived suppressor cells (MDSCs) play an important role in impairing the function of T cells. We characterized MDSCs in two chronic hepatitis C (CHC) cohorts: a cross-sectional group that included 61 treatment-naive patients with CHC, 14 rapid virologic response (RVR) cases and 22 early virologic response (EVR) cases; and a longitudinal group of 13 cases of RVR and 10 cases of EVR after pegylated-interferon-α/ribavirin treatment for genotype 1b HCV infection. Liver samples from 32 CHC patients and six healthy controls were subjected to immunohistochemical analysis. MDSCs frequency in treatmentnaive CHC was significantly higher than in RVR, EVR, or healthy subjects and was positively correlated with HCV RNA. Patients infected with HCV genotype 2a had a significantly higher frequency of MDSCs than those infected with genotype 1b. Decreased T cell receptor (TCR) ζ expression on CD8+ T cells was significantly associated with an increased frequency of MDSCs in treatment-naive CHC patients and was restored by L-arginine treatment in vitro. Increased numbers of liver arginase-1+ cells were closely associated with the histological activity index in CHC. The TCR ζ chain was significantly downregulated on hepatic CD8+ T cells in CHC. During antiviral follow up, MDSCs frequency in peripheral blood mononuclear cells was directly correlated with the HCV RNA load in the plasma and inversely correlated with TCR ζ chain expression in CD8+ T cells in both RVR and EVR cases. Notably, the RVR group had a higher frequency of MDSCs at baseline than the EVR group. Collectively, this study provides evidence that MDSCs might be associated with HCV persistence and downregulation of CD8 ζ chain expression.

Laparoscopic left hepatectomy in swine: a safe and feasible technique

Hua Zhang,Tao Liu,Yue Wang,Hai-feng Liu,Jian-tao Zhang,Yan-shuang Wu,Lei Lei,Hong-bin Wang 대한수의학회 2014 JOURNAL OF VETERINARY SCIENCE Vol.15 No.3

A purely laparoscopic four-port approach was created forleft hepatectomy in pigs. A polyethylene loop was placed onthe left two hepatic lobes for traction and lift. Next,penetrating ligation of the lobes using of a double row of silksutures was performed to control bleeding. A direct hepatictransection was completed using a monopolar hook electrodewithout meticulous dissection of the left hepatic vein. Theraw surface of the liver was coagulated and sealed with fibringlue. Lobes were retrieved through an enlarged portal. Laparoscopic hepatic lobectomy was completed in all pigswithout the use of specialized instruments and with a meanoperative time of 179 ± 9 min. No significant perioperativecomplications were observed. The average weight of eachresected lobe was 180 ± 51 g. Complete blood count as well asserum organics and enzyme levels normalized after about 2weeks. During necropsy, adhesion of the hepatic raw surfaceto the gastric wall and omentum were observed. No otherabnormalities were identified. This minimally invasive lefthepatectomy technique in swine could serve as a usefulmodel for investigating liver diseases and regeneration, andoffer preclinical information to improve hepatobiliary surgical procedures.

A Secret Sharing Scheme Based on AES

Jie Cui,Lei Chen,Yiming Zhang,Zhiqiang Xie,Hong Zhong 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6

In order to solve the key setting difficulty and the key security problem in the file encryption, key distributed storage technology may be a proper choice to help improve the safety of the key. In the paper, a novel secret sharing scheme is proposed by AES encryption algorithm for file confidentiality, dynamic key generation mechanism to generate keys, multi-secret-sharing ideas on key pre-treatment, using Shamir threshold scheme for secret dispersed storage. Finally, a few tests are carried out and the test results suggest that the efficiency of the whole scheme is good.