리눅스 기반의 IPv6 이동 네트워크 구현

김종현,이주연,이학용,정충교 강원대학교 정보통신연구소 2007 정보통신논문지 Vol.11 No.-

Mobile networks support the mobility of subnets as well as the mobility of subnets. Node mobility means that the internet connection is sustained while nodes move around. All internet connections are sustained while nodes connected on a subnet move around under the network mobility. We have implemented a mobile network system: MR (mobile Router) and HA (Home Agent) in the linux environment, confirming to the network mobility basic protocol IETF RFC3963. In this paper, we report the implementation experiences. Implementation details and some experimental results are summarized in this paper. With our implementation one can use internet service any time, and anywhere i.e., car, train, airplane, ship, etc.

난소의 원발성 유두상 이행세포암 1예

김현준,고재향,박충학 대한부인종양 콜포스코피학회 2003 Journal of Gynecologic Oncology Vol.14 No.1

난소의 원발성 이행세포암은 최근까지 조직학적으로 난소 상피 종양의 독자적인 한 종류로 인식되지 못하고 악성 Brenner 종양으로 분류되어 왔으나 악성 Brenner 종양과는 달리 항암 치료에 좋은 반응을 보이고 환자 생존율이 높은 것으로 알려지면서 하나의 중요한 조직학적 아류(subtype)로 인식하게 되었다. 이행세포암은 요로 상피의잠재력을 갖는 난소의 세포에서 직접 종양이 발생한다고 추정된다. 이행세포암은 조직학적, 생물학적으로 악성도가 매우 높은 종양으로 예후가 극히 불량하여 병기가 낮더라도 낮은 생존율을 보이는 것으로 알려져 왔으며 표준화된 치료법이 없었으나 최근에는 수술 요법과 항암화학요법을 병행 시 예후가 상당히 좋고 높은 생존율을 보이고 있다. 저자 등은 최근 38세 여성에서 그 발생 빈도가 매우 희귀한 좌측 난소의 원발성 이행세포암 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Primary transitional cell carcinoma of the ovary has been only recently recognized, as one of the main types of ovarian carcinoma because of the favorable response to chemotherapy and improved survival of the patient. Histologically, it is distinguished from malignant Brenner tumor only in the absence of benign or proliferative Brenner tumor component. Recent histopathologic reports show that transitional cell carcinoma of the bladder and of the ovary are immunophenotypically different. Primary transitional cell carcinomas are more aggressive than malignant Brenner tumor. However, primary transitional cell carcinomas have a better response to chemotherapy than other types of ovarian carcinomas. We have experienced a very rare case of primary papillary transitional cell carcinoma of the left ovary in a 38-year-old woman and report it with review of literatures.

Cross Hole Type 비 연삭 밀링 인서트의 가공특성에 관한 연구

김택수,이상민,박휘근,채승수,이충석,손일복,김학규,이종찬 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

This paper reports some experimental results on the machining performance of non-ground cross hole type milling inserts. Six kinds of milling inserts were manufactured without using grinding process. Machining experiments were carried out to compare the machining performance of non-ground inserts with that of ground ones. The experimental results indicate that the cutting forces and surface roughnesses of machined surface of both ground and non-ground inserts are comparable.

心臟血管系疾患時의 血淸 Haptoglobin 濃度에 對하여

金學仲 中央醫學社 1962 中央醫學 Vol.3 No.4

Serum haptoglobin is a fraction in the serum proteins named by Polonowski and Jayle in 1939, which is characterized by its combining property with free hemoglobin, and it normally pccupies about 25 per cent of α₂globulin. In this study I have determined serun haptoglobin levels in 24 cases o cingestive heart failure, and 10 case of cerebral cascular accident. The results revealed lower levels of serum haptpglobin than normal in congestive heart failure, and n the contrary, higher levers in cerebral vascular accident cases.

肋膜疾患의 臨床的 考察 : 非特異性肋膜?出에 關한 診斷的 考察 1.Diagnostic Studies on Idiopathi Pleural Effusions

金洋一,李英玉,金東秀,李學重 中央醫學社 1976 中央醫學 Vol.30 No.2

Twenty-three patients with pleural effusion of unknown etiology were selected because by means of radiological and cytologic examination, smear of the sputum and pleural fluids for tubercle bacilli and eggs of the lung fluke had failed to provide a diagnosis, from September, 1974 to October, 1975 at the Department of internal Medicine, National Medical Center in Korea. Needle biopsy of the pleura using Vim-Silverman needle, culture of the sputum and pleural fluids for tubercle bacilli, red blood cell, lymphocyte, monocyte and mesothelial cell counts in the pleural fluids, and measurement of the pleural fluid glucose and pH levels were done to provide definite or suspected diagnosis. The results were as follows: 1) neeedle biopsies were done on 23 patients and 11 of these showed tuberculous findings, 2 of these showed lymphoma and the remaining 10 showed nonspecific chronic inflammation (43.5%). In one patient of the nonspecific group, an open pleural biopsy which showed paragonimiasis. 2) culture of the pleural fluid was positive for tubercle bacilli in only 2 of the tuberculous group and 1 of the nonspecific group. 3) Used in conjunction with pleural fluid red blood cell, lymphocyte, monocyte, rresothelial cell counts and glucose, pH levels, most provable tuberculous etiology could be established in 6 of 8 nonspecific group, and remaining 2 were as idiopathic pleural effusion. There was no significant statistical difference in the laboratory

低溫光反應 裝置의 製作과 이를 利用한 테트라페닐디아조시클로펜타디엔의 低溫光反應

李學沂,金鴻洛,李忠熙 慶北大學校 1987 論文集 Vol.44 No.-

The apparatus for low temperature photoreaction is very useful one for detecting reactive intermediates such as carbene, benzyne etc. So, the major portion of this work dealt with the construction of apparatus for low temperature photoreaction. And tetraphenyldianzocyclopentadiene was synthesized as a precursor by reaction of benzil with 1, 3-diphenylacetone and p-toluenesulfonylhydrazide. Using this apparatus constructed for low temperature photoreaction, tetraphenyldiazocyclopentadiene was irrdiated by UV (λ>280nm) at 10K, 7 exp (-6)mbar. Irradiation of tetraphenyldiazocyclopentadiene through quartz window at 10K gave three new strong IR peaks; 2,110 cm^-1, 1,675cm^-1, and 765cm^-1. Comparison with the results of matrix isolated study of diazocyclopentadiene, it was believed photoproducts to be tetraphenylcyclopentadienylidene (765cm^-1) as carbene and tetraphenylcyclopropenylallene (2,110cm^-1, 1,675cm^-1) formed by intramolecular rearrangement of the carbene.

자궁경부암 선별검진을 위한 PapSure 검사에서 Spiral Brush의 유용성에 관한 연구

송언호,김어진,명나혜,박충학 대한부인종양 콜포스코피학회 2002 Journal of Gynecologic Oncology Vol.13 No.4

2001년 12월 1일부터 2002년 6월 30일까지 만 7개월 간 단국대학교의료원 산부인과 부인종양 Clinic에서 자궁경부암 선별검진을 위한 PapSure 검사를 시행한 환자 중 SpiraBrush Cx_® 검사를 실시한 33예를 대상으로 하여, 기존의 Papanicolaou 세포진 검사의 진단과 SPiraBrush Cx_®)에 의한 Papanicolaou 세포진 검사의 진단 및 최종적인 병리조직학적 진단을 비교, 분석하여 SpiraBrush Cx_®에 의한 세포진 검사가 생검에 의한 조직검사를 대체할만한 유용성이 있는지 그 여부를 조사하기 위하여 본 연구를 시행하여 다음과 같은 결과를 얻었다. 1. 환자의 연령별 분포는 21세에서 70세까지였으며 40-49세 군이 42%로 가장 많은 분포를 보였고, 평균 연령은 45.7세였다. 2. 환자의 평균 임신횟수는 3.6회였으며, 평균 출산횟수는 2.0회였다. 3. 기존의 자궁경부 세포진 검사(Conventional Papanicolaou cytology)상 진단이 음성으로 나온 경우가 19예(57.6%)였고, ASC를 포함하여 양성으로 나온 경우가 14예(42.4%)였다. 자궁경부 형광경진 검사(Speculoscopy)에서는 음성이 13예(39.4%)였고, Suspicious 진단을 포함하여 양성으로 나온 경우가 20예(60.6%)였다. SpiraBrush Cx®에 의한 세포진 검사(SpiraBrush Cx_® Papanicolaou cytology)에서는 진단이 음성인 경우가 8예(24.2%)였고, ASC를 포함하여 양성으로 나온 경우가 25예(75.8%)였다. 4. 병리조직학적 검사의 진단은 음성 12예(52.2%), 저등급 편평상피내병변(Low-grade Squamous Intraepithelial Lesion: 이하 LSIL이라 함) 2예(8.7%), 고등급 편평상피내병변(High-grade Squamous Intraepithelial lesoin: 이하 HSIL이라 함) 3예(13.0%), 편평세포암(Squamous Cell Carcinoma: 이하 SCC라 함) 6예(26.1%)였다. 5. 검사 결과의 양성판정 기준을 세포진 검사의 경우는 ASC 이상으로 하고 조직학적 검사의 경우는 LSIL이상으로 정할 경우, 기존의 Papanicolaou 세포진 검사의 민감도는 63.6%이고 특이도는 66.7%였으며, SpiraBrush Cx_®세포진 검사의 민감도는 90.9%이고 특이도는 33.3%였다. 이상의 결과로 미루어 볼 때 연구 대상의 숫자가 적어서 통계학적인 유의성은 찾을 수 없으나 SpiraBrush Cx_®가 자궁경부암 선별검진에서 생검에 의한 자궁경부의 조직학적 진단을 대체하지는 않는다고 판단된다. 그러나 기존의 Papanicolaou 세포진 검사의 민감도가 63.6%인데 반하여 SpiraBrush Cx_® 세포진 검사의 민감도는 90.9%로 훨씬 더 높았으며 이로 인해 SpiraBrush Cx_® 세포진 검사의 특이도는 33.3%로 훨씬 낮았는데 이는 매우 흥미있는 사실로서 향후 많은 Data로 더욱 연구하여 진위를 구분함이 필요하리라 사료된다. 또한 본 연구에서는 SpiraBrush Cx_® 기구의 강모들이 단단하고 날카로워서 기저막층까지의 조직과 상피층 세포들을 탈락시키면서 많은 출혈을 초래하여 슬라이드 판독에 어려움을 주었고 이는 연구 결과에 지대한 영향을 미쳤으리라고 생각되는 바, 이러한 출혈로 인한 요인을 최대한 배제하기 위하며 향후 SpiraBrush Cx_® 세포를 채취한 후 최신의 자궁경부 세포진 검사법인 ThinPrep Pap Test를 이용하거나 조직표본을 만들기 위한 Cellblock 기법을 사용하여야 한다고 판단된다. Objective : The purpose of this study was to investigate the clinical efficacy of a new stiff bristled spiral shaped brush (SpiraBrush Cx_(??))∼in) PapSure Test for cervical cancer screening, by comparing SpiraBrush Cx_(??) cytologic diagnoses with conventional Papanicolaou cytologic diagnoses and final histologic diagnoses. Methods : This study was performed in Gynecologic Oncology Clinic of Department of Obstetrics and Gynecology at Dankook University Medical Center from December I, 2001 to June 30, 2002. Thirty three cases who underwent PapSure Test (Pap cytology t Speculoscopy) were analyzed. SpiraBrush Cx_(??) Papanicolaou cytologic diagnoses were compared with conventional Papanicolaou cytologic diagnoses and histologic diagnoses as a reference standard. Results : Followings are the results summarized. 1. Age distribution was between 21 and 70. The mean age was 45.7 years. 2. The mean gravidity was 3.6 and the mean parity was 2.0. 3. There were 19 (57.6%) conventional Papanicolaou cytologic diagnoses of Negative, and 14 (42.4%) of Positive including ASC. There were 13 (39.4%) Speculoscopy diagnoses of Negative, and 20 (60.6%) of Positive including Suspicious. There were 8 (24.2%) SpiraBrush Cx_(??) cytologic diagnoses of Negative and 25 (75.8%) of Positive including ASC. 4. There were 12 (52.2%) histologic diagnoses of Negative, 2 (8.7%) of LSIL, 3 (13.0%) of HSIL, and 6 (26.1%) of SCC, according to the criteria of TBS, 2001. 5. For detecting LSIL or worse lesions, conventional Papanicolaou cytologic test yielded sensitivity of 63.6% and specificity of 66.7%. On the other hand, SpiraBrush Cx_(??) cytologic test yielded sensitivity of 90.9% and specificity of 33.3%. Conclusion : SpiraBrush Cx_(??) cytologic diagnosis does not seem to have clinical efficacy replacing the histologic diagnosis by punch biopsy in cervical cancer screening in this study. But further studies using ThinPrep Pap Test or Cellblock techniques with large data will be required and anticipated.

인슐린 비의존형 당뇨병 환자에서 혈장 Endothelin-1농도의 변화

신양수,조희충,김원식,국기용,김용화,정종훈,문철웅,배학연,양성훈 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Endothelin(ET) is a 21-residue peptide originally isolated from the cultured porcine endothelial cells. There are at least three genes for endothelin:endothelin-1(ET-1), endothelin-2(ET-2), and endothelin-3(ET-3). Endothelins are present in various human biological fluids including plasma, urine, breast milk, and saliva and have been found elevated plasma ET concentrations in patients with diabetes mellitus, Patients undergoing maintenance hemodialysis due to chronic renal failure, patients with acute myocardial infarction, and patients with subarachnoid hemorrhage. Endothelial cell damage is suspected to occur in diabetic patients and may be one important cause of angiopathy, a major complication in diabetes mellitus. The elevation of ET in diabetic patients may be a marker of, and further exacerbate, their vascular disease. We measured the levels of ET-1 in plasma of 50 patients with non-insulin dependent diabetes mellitus(NIDDM) and 25 normal subjects by radioimmunoassay. The plasma ET-1 concentration (mean±S.D.) in NIDDM was 6.461 A2.510 f㏖/ ㎖, and was significantly higher than in normal subjects (4.567±1.155f㏖/㎖) (P<0.05). The plasma ET-1 concentration (mean±S.D.) in diabetic retinopathy group( 7.15±2.454 f㏖/ml) was significantly elevated than those in otherwise uncomplicated groups (5.348±2.390 f㏖/㎖)(P<0.01). The correlation between any clinical parameters and plasma ET-1 levels in NIDDM was not significant, In conclusion, this study suggest that the elevated levels of ET-1 in diabetic patients may be play a important role in the pathogenesis of diabetic complications.

유기용제노출이 직업적 청력손실에 미치는 영향

이지호,고영주,이헌,강정학,유철인,이충렬,김양호 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.4

목적 : 산업 장에서 노출되는 유기용제가 청력역치에 어떠한 영향을 미치는가를 5년 동안의 추적조사를 통하여 파악하고자 하였다. 방 법 : 유기용제와 소음에 동시에 노출된 근로자 43명과 소음노출수준, 연령, 근무경력을 짝짓기 한소음노출군을 대상으로 문진과 이경검사, 소음노출 수준, 유기용제노출수준을 조사하였다. 결과 : 1. 전체 근로자의 각 주파수별 청력역치 변화양상에서 500Hz∼2000Hz에서는 추적기간 동 소음동안 현저한 변화가 없었고, 4000Hz 및 8000Hz에서는 역치가 증가하는 경향을 나타내었다. 2.유기용제와 소음에 동시에 노출된군에서 소음 노출군에 비해 4000Hz 이상에서 청력역치가 높게 나타났으나, 통계적인 유의성은 없었다(p(0.05). 3.반복측정 분산분석 법으로 각 주파수별 평균청력 역치의 연차적 변화에 미치는 영향을 분석한 결과 유기용제 노출은 통계적으로 유의한 영향이 없었으나(p)0.05), 소음노출수준은 250Hz, 2000Hz 및 4000Hz에서, 연령은 250Hz와 500Hz에서 통계학적으로 유의한 영향을 미치는 것으로 나타났다(p(0.05). 4.소음노출군파 동시노출군 각각에서의 청력역치 변화량을 paired t-test로 비교한 결과 250Hz∼4000Hz에서는 통계학적 유의성이 없었으며(p(0.1), 8000Hz에서만 경계치 (p=0.0884)의 유의성을 나타내었다. 5.요인들의 영향을 보정한 상태에서 관찰하기 위해 관찰기간동안의 청력역치변화량을 종속변수로 두고 일반선형모형을 이용하여 주파수별로 관찰한 결과 8000Hz에서만 모델에 통계학적 유의성이 있었으며 (p(0.05), 여기서 소음노출수준이 통계학적으로 유의한 영향을 미치는 것으로 나타났고(p(0.05), 유기용제노출은 경 계수준이 었다(p=0.087). 결론 : 청력에 대한 유기용제의 영향이 소음과 연령에 비해 상대적으로 미미하여 명확한 결론에 이르지는 못하였으나, 다소 영향이 있는 것으로 생각되어 유기용제의 영향에 대한 추가연구가 필요할 것으로 판단된다. 또한 보다 효과적인 근로자들의 청력관리를 위해서는 소음 외 산업 장에서 동시에 노출되는 여러 유해물질들을 고려하여야 할 것이다. Objectives : This study was to evaluate the impacts of simultaneous exposure to noise and mixed solvents on workers'hearing threshold level (HTL) over five-year period. Methods : The study was conducted by interview and annual audiometric test on workers in ship building industry from 1994 to 1998. The cases(workers who exposed to noise and mixed solvent simultaneously) were 43 male workers and controls (workers who exposed to nolle) were selected by matching method with regard to age, sex, carrier, and noise exposure level. To assess the impacts of solvent exposure on hearing threshold level, with considering other factors, general liner model was used. Results : 1. The audiogram of all subjects showed typical sensorineural hearing loss pattern. The mean HTLe were increased at high frequency (4000HB and 8000Hz) for study period. 2. The HTLs of cases were more increased than those of controls at high frequencies (4000Hz and 8000Hz), but there was not statlstical significance. 3. The impact of age on the HTL was statistically significant at 250Hz and 500Hz (p(0.05), and the impact of noise on the HTL was statistically significant at 250Hz, 2000Hz and 4000Hz (p(0.05), but the impact solvent exposure on the HTL was not significant. 4. The changes in HTLs of cases were higher than those of controls at high frequency, there were not statistical significance at 4000Hz, but only at 8000Hz (p=0.087). 5. Statistical analysis of the general linear model implicated that the changes in HTL was impacted by noise exposure bevel significantly (p=0.031) and Impacted by solvent exposure weakly (p=0.087) at 8000Hz. Conclusions : The results of this study suggest that workers who simultaneously exposed to noise and mixed solvent were at risk for more affected HTL than those exposed to noise exposure only, but we could not find definitive evidence. Further detailed studies must be made in large number of workers.

상악동 후비공 용종에서 줄기의 경로에 따른 상악동구 전산화단층촬영 소견

이승훈,박동우,이승로,함창곡,이학수,김용수,박충기 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.2

Purpose: We evaluate the pathway of the stalk of antrochoanal polyp on the coronal and axial computed tomography scans (CT), comparing with operative findings. Materials and Methods: Fourteen patients (7∼40 years old, median= 12.5 years old, ratio of male to female: 8/6) with antrochoanal polyp were examined, who took the orbitomeatal unit (OMU) CT including both coronal and axial scans as well as the operation. The CT findings and clinical findings were analyzed for the pathway of the stalk of antrochoanal polyp, comparing with the operative findings. Results: The antrochoanal polyps were mostly located on the left side (12/14, 85.7%) and equally passed through the natural and accessory ostia (7/14, 7/14) in our cases. Those that were passing through the accessory ostium were located more inferiorly and posteriorly, with preserving the natural ostium on CT scans, comparing to those via the natural ostium. However, those passing through the natural ostium had a larger stalk that eroded the uncinate process widely. So each ostium was hardly discriminated on CT scans. Conclusions: The pathway of the stalk of the antrochoanal polyp could be more specifically evaluated on both coronal and axial OMU CT scans. So, it could be more hilpful in the presurgical planning.