열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

30% Minocycline 국소 약물송달제제의 생체내, 외방출역학, 세포독성 및 세포활성도 측정

최현순,이상철,김강주,장원규,정서영,정종평 대한구강생물학회 1992 International Journal of Oral Biology Vol.16 No.1

Present study was performed to examine in vitro and in vivo release kinetics, cell cytotoxicity and cellular growth survival of local 30% Minocycline delivery. The purpose of this study was to determine the possibility of clinical use of 30% Minocycline load polycaprolactone film(Mino-Strip). The size of Mino-strip is 6.5㎜×2.5㎜×0.3㎜, Mwt: 5.7㎎). In vitro releasing test, each film showed a large initial burst effect within first one and two hours and more than 84% of Minocycline was releasing test, each film showed a large burst effect within first two and three hours. A steady state kinetics was observed for 8 days both in vivo and in vitro releasing test. In cytotoxicity test, there was no significant cytotoxic effect in Mino-strip to human gingival fibroblast. In cellular growth survival test, there was no significant cellular growth survival effect in Mino-strip to human gingival fibroblast.

熱處理 硬化層을 고려한 有限要素解析의 試圖

최윤용,조상봉,김태규 慶南大學校 附設 工業技術硏究所 2003 硏究論文集 Vol.21 No.1

표면을 열처리한강은 어떤 깊이에 대하여 일반적으로 경도의 변화층을 가지고 있다고 잘 알려져 있다. 이것은 기계적 특성이 다른 두 재료를 붙여 놓은 것과 같은 이종재료간 접합구조물로 생각할 수 있을 것이다. 열처리 후에는 재료의 성질이 변화하는 것으로 알려져 있고, 경도 및 인장강도 등이 변화하는 물성치의 예이다. 그런데 재료의 탄성계수와 푸아송의 비가 열처리 후에 달라지는지에 대한 연구 결과는 찾기가 어렵다. 본 연구에서는 SM45C강 환봉의 열처리한 후에 탄성계수와 푸아송 비의 변화에 대하여 실험적으로 규명하고 열처리 경화층을 이종재료의 층으로 고려하여 탄성 응력해석해야 할지를 한 가지의 해석모델을 설정하여 검토하였다. In general, it is well known that the surface heat-treated steel has a certain depth of hardened layer with different hardness. The surface heat-treated steel can be thought as a dissimilar structure bonded by two materials which have different mechanical properties. Material properties are changed by heat treatment and hardness, tensile strength etc. are examples of changing material properties. To author's knowledge, it is difficult to find out the results of study for elastic modulus and Poisson's ratio of heat-treated materials. In this paper. Elastic modulus and Poisson's ratio for the heat-treated SM45C steel rod were investigated experimentally. Elastic finite element analysis was also performed to investigate that the surface heat-treated hardened layer must be considered as a dissimilar structure.

디이젤기관의 연소특성에 관한 연구(Ⅰ)

최두석,김창현,조규상,류정인 忠南大學校 産業技術硏究所 1987 산업기술연구논문집 Vol.2 No.1

A Computer program for the precombustion chamber type 4 cycle C.I.engine using two-zone model and quasi-steady model has been developed. Comparing with experimental results, the calculated results have about 10% of deviation. Through the numerical analysis, the direction of optimum engine design condition can be obtained as follows; 1) From the numerical solution, the optimal driving points of experimental engine are as follows. Engine speed is 2500 - 3000rpm and the injection timing is 15-20。BTDC, When the economy of fuel is considered, and when the engine is driven under 2100 rpm and fuel is injectioned at 25。BTDC, the maximum output can be obtained. 2) The maximum cylinder pressure increase about 3% at every 400 rpm, and increase about 20% whenever the injection time is advanced at 5 degrees. 3) The volumetric efficiency decrease about 9% at every 400rpm.

Semiclassical Analysis for O + Pb Elastic Scattering at E=216.6 and 312.6 Mev

최치규,현남규,김용주,홍성락 제주대학교 1992 논문집 Vol.34 No.-

실험실계에서의 입사핵?? 에너지가 216.6과 312.6 MeV이고 표적핵?? 인 탄성산란에 대한 실험데이타를 수정된 Glauber모델을 사용하여 분석하였다. 계산된 결과들은 실험데이타와 좋은 일치를 보여주었다. .

수근관 증후군의 국소 스테로이드 주사

조민규,이성훈,강은영,전평식,최영태 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.5

띠간 자기광학 전이에서 두 다체 사영방법의 비교

최상돈,김영미,이연주,석적영,조상규 慶北大擧校 師範大學 科學敎育硏究所 2000 科學敎育硏究誌 Vol.24 No.-

If we apply a circularly polarized light to semiconductors, in the external static magnetic field, then the electrons absorb the light at the resonance frequency, resulting in the interband-transition from valence band to conduction band. The linewidth is affected by various mechanisms. Here we will compare the isolated operator method and the single operator method.

골수염의 진단에 있어서의 Tc-99m Hexamethylpropylene amine oxime 백혈구 스캔의 임상적 유용성

최상호,김양수,정준원,정진원,추은주,서동대,배인규,양승오,우준희,류지소 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

배경 : 골수염의 진단에 있어 Technetium-99m을 이용한 삼상 골스캔(Tc-99m MDP스캔)은 단순방사선 검사상 정상소견을 보이는 경우에 쓰이는 1차적 검사로 매우 높은 민감도를 보인다. 그러나 Tc-99m MDP 스캔은 골절이나, 정형외과적 삽입물, 신경병적 관절병변과 같이 뼈의 재형성이 증가되는 상황에서도 양성소견을 보여 특이도가 낮은 단점이 있다. 이러한 단점을 보완하고자 골수염의 진단에 있어 Tc-99m HMPAO 백혈구 스캔의 유용성을 알아보고자 하였다. 대상 및 방법 : 골수염이 의심되어 Tc-99m HMPAO 백혈구 스캔을 시행했던 15명의 의무기록을 후향적으로 분석하였다. 골수염의 확진은 임상관찰 소견과 배양검사 결과와 병리소견을 기준으로 하였다. 결과 : 골수염의 진단에 있어 Tc-99m HMPAO 백혈구 스캔의 민감도와 특이도는 각각 100%와 78%였고 Tc-99m HMPAO 스캔의 경우는 100%와 18%였다. 가장 흔한 원인균은 methicillin-resistant S. aureus였다. Tc-99m MDP 스캔에서 양성소견을 보였던 환자중 3명의 환자가 Tc-99m HMPAO 백혈구 스캔에서 음성 소견을 보였으며 이 환자들은 추적관찰상 골수염이 없는 것으로 확인되었다. 결론 : Tc-99m HMPAO 백혈구 스캔은 골수염의 존재를 진단하는데 있어 민감도와 특이도가 높으며, 특히 뼈의 재형성이 증가되어 Tc-99m MDP 스캔의 특이도가 낮게 나타나는 상황에서 유용하리라 사료된다. Background Three phase bone scintigraphy, performed with technetium-labeled diphosphonates (Tc-99m MDP scan), is the very sensitive radionuclide procedure of choice for diagnosing osteomyelitis. But, Tc-99m MDP scan is less specific when bone remodeling is increased. To overcome this limitation, we evaluated the diagnostic value of technetium-99m hexamethylpropyleneamine oxime (HMPAO) labeled leukocyte scan in osteomyelitis. Methods : We retrospectively reviewed 15 patients with suspected osteomyelitis who performed Tc-99m HMPAO labeled leukocyte scan. The diagnosis of osteomyelitis was based on clinical course and bacterial culture, and pathologic findings. Results The sensitivity and specificity of Tc-99m HMPAO leukocyte scan was 100% and 78%, and those of Tc-99m MDP scan was 100% and 18%, respectively. The most common organism was Methicilein-Resistant S. aureus. Among the patients that showed persistent accumulation on Tc-99m MDP scan, three patients showed no uptake on Tc-99m HMPAO leukocyte scan and these patients were confirmed that had no osteomyelitis. Conclusion : Tc-99m HMPAO leukocyte scan is a useful test for determining the presence or absence of osteomyelitis, especially under condition that bone remodelin is increased.

벼 밭재배에 따른 수량 및 미질

최원영,최민규,김상수,이규성,김태수,이재길 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.4

벼 밭재배시 논벼 품종들의 적응성을 검토하기 위하여 마늘 간작으로 벼를 건답점파하여 재배한 결과를 요약하면 다음과 같다. 1. 입모율은 밭벼에 비해 논벼 품종이 낮았는데 그 순서는 상남밭벼〉동진찰벼〉신선찰벼〉진부찰벼 순이었다. 2. 출수기는 상남밭벼에 비해 진부찰벼는 3일 빨랐고 신선찰벼는 9일, 동진찰벼는 12일이 늦었다. 3. ㎡당 수수와 등숙비율은 밭벼에 비해 논벼품종들이 높았다. 4. 쌀수량은 상남밭벼에 비해 신선찰벼는 12%가 많았고 동진찰벼는 같았으며, 진부찰벼는 18%가 적었다. 5. 완전립비율은 진부찰벼에서 높았고 그 외는 비슷하였으며, 식미지수는 상남밭벼에 비해 동진찰벼는 높았으나 진주찰벼와 신선찰벼는 낮았다. To identify the rice varieties adaptable for upland cultivation, a series of experiments was carried out at the field(Chonnam series) of the Muan. Cheonnam province during 1999 - 2001. Four varieties, Jinbuchalbyeo(early-maturing variety), Sinseonchalbyeo (medium-maturing variety), Dongjinchalbyeo(medium-late maturing variety), and Sangnambatbyeo as a standard variety for upland were used in this experiment. Seedling establishment of the varieties was the highest in Sangnambatbyeo and followed by Dongjinchalbyeo under upland condition. Heading date in general delayed ranges from 9 to 12 days, while early-maturing variety, Jinbuchalbyeo was faster for 3 days compared with Sangnambatbyeo. Number of panicle per square meter was similar in both lowland and upland rice but percentage of ripened grain was high in lowland rice. Milled rice yield was high as of 12% in Sinseonchalbyeo compared with Sangnambatbyeo. Head rice ratio showed also the highest in Sinseonchalbyeo. The results indicate that Sinseonchalbyeo as glutinous rice variety could adapt well in this upland condition, and have good milling recovery as head rice as well as yield advantage.

자기-광전이 형식을 유도하는 두 가지 다체사영연산자 방법의 비교

최상돈,이현정,석적영,조상규,강남룡 慶北大擧校 師範大學 科學敎育硏究所 2000 科學敎育硏究誌 Vol.24 No.-

We consider a magneto-optical transition theory based on the many-body projection technique. And we use two kinds of projectors ; projection-isolation operators and projection operators. The second method turns out to be more convenient than the first method.