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Han-Jung Chae,Jang-Sook Kang,Byung-Gwan Bang,Seoung-Bum Cho,Jo-IL Han,Joo-Young Choi,Hyung-Min Kim,Soo-Wan Chae,Hyung Ryong Kim 대한생리학회-대한약리학회 1999 The Korean Journal of Physiology & Pharmacology Vol.3 No.6
<P> Bone is a complex tissue in which resorption and formation continue throughout life. The bone tissue contains various types of cells, of which the bone forming osteoblasts and bone resorbing osteoclasts are mainly responsible for bone remodeling. Periodontal disease represents example of abnormal bone remodeling. Osteoclasts are multinucleated cells present only in bone. It is believed that osteoclast progenitors are hematopoietic origin, and they are recruited from hematopoietic tissues such as bone marrow and circulating blood to bone. Cells present in the osteoclast microenvironment include marrow stromal cells, osteoblasts, macrophages, T-lymphocytes, and marrow cells. These cells produce cytokines that can affect osteoclast formation. In vitro model systems using bone marrow cultures have demonstrated that IL-1β, IL-3, TNF-α, bFGF can stimulate the formation of osteoclasts. In contrast, IL-4 inhibits osteoclast formation. Knowledge of cytokines and bFGF that affect osteoclast formation and their capacity to modulate the bone-resorbing process should provide critical insights into normal calcium homeostasis and disorders of bone turnover such as periodontal disease, osteoporosis and Paget s disease.
崔炯一,林官圭 조선대학교 환경연구소 1988 環境公害硏究 Vol.5 No.-
This study was carried out to investigate the heavy metal content of freshwater fishes which were collected at 7 areas located on Youngsan river from march to april in 1988. The results obtained were as follows : 1. Generally mean value of heavy metal contents of fishes collected on lower and upper parts of Youngsan river were higher than those of middle parts. 2. The highest percent of water in edible portion of samples was 81.5% in cyprinus carpio, the lowest was 74.7% in Pseudogobio esocinus, and. the other samples were 75.3% to 78.0. 3. In the cadmiuum contents, the highest value was 14.67 ppb in Carassius auratus and the value at Dongmal ferry area was higher than those at other parts on Youngsan river. 4. In the lead contents, the highest was 0.236 ppm in carassius auratus and that in Zacco platypus was the lowest 0.112 ppm, 5. In the copper contents, the highest value was 2.007ppm in Carassius auratus and the contents of fishes of fishes of dongmal ferry was higher than those of any other area. 6. In the chromium contents, the highest was 1.102ppm in carassius auratus and that in zacco playpus was the lowest 0.887 ppm. The contents of samples of Dongmal ferry area was also higher than those of other area. 7. Accumulation of heavy metals in freshwater fishes intended to increase with growth.
고소현,박관수,강길남,방병욱,김동일 충남대학교 농업과학연구소 2005 농업과학연구 Vol.32 No.1
This study was carried out to examine the effect of heavy traffic on chemical properties of soil in roadside trees of Daejeon city. Soil samples at 0~10cm and 10~30cm depths were collected from soil of the roadside trees, Platanus occidentalis. and Ginko biloba. Soil pH in heavy traffic regions were around 7.0 at 0~10 cm and 10~30cm soil depths because of spraying of calcium chloride for snow moving. The concentrations of Fe, Cd, Cu, Zn, and Pb in soil were higher in heavy traffic regions(Daejeon Station and Daehwa Industrial Complex) than in light traffic region(Chungnam National University). The result could be from rubbing and wear of car tire and metals when they travel.
박관창(Gwan-chang Park),천영식(Young-sig Cheon),박일호(Il-ho Park),최형일(hyeong-Il Choi),박봉석(Bong-Suk Park),김은식(Eun-Sig Kim),김인대(In-Dae Kim) 대한전기학회 2010 대한전기학회 학술대회 논문집 Vol.2010 No.7
본 논문에서는 발전플랜트와 같은 소내전력계통의 보전력시스템관련 데이터 및 응용 프로그램등의 자원들을 통합관리하고 원격제어기술을 이용 Server의 자원을 원격지에서 효율적으로 이용할 수 있는 Web기반의 소프트웨어 개발한 사례에 관하여 언급하였다. Web기반의 소프트웨어 개발환경과 각 구성시스템 자원들을 어떻게 이용하여 Server의 자원들을 어떻게 효율적으로 이용하는가에 관하여 기술하였다.
대장 폴립형 선종과 비교한 편평 선종의 임상 및 병리학적 특성과 악성화 빈도
지명관 ( Myeong Gwan Jee ),김현수 ( Hyun Soo Kim ),김원호 ( Won Ho Kim ),김태일 ( Tae Il Kim ),박동일 ( Dong Il Park ),김영호 ( Young Ho Kim ),김효종 ( Hyo Jong Kim ),변정식 ( Jeong Sik Byeon ),양석균 ( Suk Kyun Yang ),이문성 ( Mo 대한장연구학회 2005 Intestinal Research Vol.3 No.2
목적: 대장 선종의 육안형태에 따른 악성화 가능성은 초기 연구에 있어 편평 선종이 폴립형 선종에 비해 조기 대장암이나 고도 이형성의 동반율이 높다고 보고되었으나 최근 연구들은 육안형태에 따른 차이가 없음을 보고해 논란이 있다. 본 연구는 전향적 다기관 연구를 통하여 국내 대장 편평 선종의 임상병리학적 특성을 폴립형 선종과 비교하고 악성화 가능성의 지표인 고도 이형성이나 조기암의 동반을 결정하는 위험인자를 알아보고자 하였다. 대상 및 방법: 2003년 7월부터 2004년 7월 까지 국내 11개 대학병원에서 전 대장내시경 및 폴립 절제술을 받은 4,412명 중 선종으로 진단된 3,360명(평균 나이:57.3세, 남자:2,383명, 여자:977명)을 대상으로 육안 형태 및 병리학적 기준에 따라 대장의 편평 선종군과 폴립형 선종군으로 구분하였다. 양 군에서 임상병리학적 특성을 비교하였고 악성화 가능성의 지표로 고도 이형성과 조기 암의 동반에 관련된 위험 인자를 알아보고자 성별, 연령, 대장 선종의 크기, 위치, 융모 선종의 함유여부, 육안 형태의 여러 요인에 대한 다변량분석을 시행하였다. 결과: 3,360명의 선종 환자 중 편평 선종은 207명으로 6.2%를 차지하였다. 편평 선종은 폴립형 선종에 비해 크기가 컸으며(10.6 mm vs. 9.2 mm, p<0.01) 고령에서(59.6세 vs. 57.1세, p<0.01) 우측 대장(49% vs. 32%, p<0.01)에 호발하였다. 그러나 성별, 체질량 지수, 동반 선종의 개수나 분포는 양 군간에 차이를 보이지 않았으며 육안형태에 따른 진행성 선종이나 암의 동반빈도에 차이를 보이지 않았다(5.4% vs. 4.6%, p=0.36). 다변량분석 결과 대장 선종의 악성화 가능성은 육안형태에 따른 차이는 없었으며 대장 선종의 크기가 11 mm 이상인 경우(OR 6.8, 95% [CI], 4.8-9.7)와 좌측 대장에 위치한 경우(OR 1.6, 95% [CI], 1.1-2.5) 위험도가 증가하였다. 결론: 국내에서 대장의 편평 선종은 고령의 환자에서 우측 대장에 호발하므로 선별검사로서 대장내시경이 유리하며 악성화 가능성을 결정하는 위험인자는 대장 선종의 육안형태가 아니라 선종의 크기와 위치임을 알 수 있었다. Background/Aims: Colorectal flat adenomas have been a topic of debate in the view of malignant potential. The aims of this study are to investigate the clinicopathological features of flat adenomas compared to that of polypoid adenomas and to identify the determinants for malignant transformation in colorectal flat and polypoid adenomas. Methods: This was a prospective, cross sectional study of 3,360 patients who diagnosed as adenomas via total colonoscopy and polypectomy at 13 tertiary medical centers between July 2003 and July 2004. Potential risk factors for malignant transformation were analyzed. Results: Out of 3,360 adenomas, 207 (6.2%) were flat adenomas and 3,153 (93.8%) were polypoid adenomas. The patients with flat adenoma were older (59.6 vs. 57.1, p<0.01) and more frequently located in the right colon than polypoid adenomas (49.3% vs. 32.0%, p<0.01). The incidence of high grade dysplasia or cancer in flat adenomas was similar to that of polypoid adenomas (5.4% vs. 4.6%, p=0.36). Multivariate analysis revealed that the size ≥11 mm (OR 6.8; 95% CI 4.8-9.7) and location of adenoma in the left colon (OR 1.6; 95% CI 1.07-2.38) were significant determinants for malignant potential of colonic adenoma. Conclusions: Clinicopathological determinants for malignant potential in colorectal adenomas were not gross morphology but size and location of adenoma. (Intestinal Research 2005;3:127-132)