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도시 치과의료 이용자의 진료내역 및 만족도에 관한 연구
안금선,유정숙 경복대학 2002 京福論叢 Vol.6 No.-
1. 치아경조직 질환은 25세미만과 35세미만에 높게 나타났고, 치수 및 근단조직질환은 30세미만, 치은 및 치주질환은 30~35세미만에서 높게 나타났다. 성별로는 남자가 여자보다 전체적으로 높게 나타났다. (1) 전체 내원환자의 상병분포를 살펴보면 치수 및 근단조직(42.5%)으로 내원한 경우가 가장 많았다. 2. (1) 치아경조직 질환의 처치는 즉처(85%)한 경우가 발치(15%)한 경우보다 높게 나타났다. 따라서 치아경조직 질환의 처치는 즉처가 대부분을 차지함을 알 수 있다. (2) 치수 및 근단조직 질환의 처치는 치수치료(81.5%)한 경우가 발치(18.5%)한 경우보다 높게 나타났다. (3) 치은 및 치주질환의 처치는 치주질환수술(치석제거포함)한 경우가 86.8%로 높게 나타났다. 3. (1) 치과진료 만족도는 성별 및 연령별로는 커다란 차이없이 치과진료에 대해 만족한 것으로 나타났다. 상병처치에 따른 치과진료 만족도를 살펴보면 치아경조직질환에서는 즉처한 경우가 발치한 경우보다 높았으나 유의미한 차이는 아니었다. 치수 및 근단조직 질환과 치은 및 치주질환에서는 발치한 경우가 높게 나타났다. (2) 진료비에 대찬 인식은 성별 및 연령별로는 커다란 차이없이 보통이다라고 인식한 경우가 72.8%로 대부분을 차지하였다. 또한 상병의 처치에 따른 진료비에 대한 인식은 치아경조직 질환에서는 발치한 경우, 치수 및 근단조직질환에서는 처치의 대부분을 차지하는 치수치료를 한 경우, 치은 및 치주질환에서는 발치한 경우 진료비가 보통이다라고 인식하였다. 1. The dental hard tissue diseases were more prevalent in the age groups under 25 and 35, and pulp and periapical diseases were more common in the age group under 30. The gingival and periodontal diseases developed more frequently (among those aged 30 to 34. By gender, the male patients had more dental diseases than the females did. (1) Overall, the largest number of the patients(42.5%) suffered from pulp and periapical diseases. 2. (1) For dental hard tissue diseases, immediate treatment(85%) was more utilized than extraction(15%). Therefore, it could be said that this type of diseases mostly resorted to immediate treatment. (2) In the case of pump and periapical diseases, pulp treatment(81.5%) was more often employed than extraction(18.5%). (3) Regarding treatment for gingival and periodontal diseases, periodontal operation(85.8%), which included scaling, was dominant. 3. (1) The patients expressed satisfaction at dental treatment they received, and their gender and age made little notable differences to that. Concerning satisfaction level with the type of treatment, they found immediate treatment more satisfactory, than extraction, for dental hard tissue diseases, but the gap between the two wasn't significant. The extraction gave a greater satisfaction in the case of pump and periapical diseases or gingival and periodontal diseases. (2) The majority of the patients(72.8%) 'esponded they couldn't complain about the medical costs, regardless of gender and age. By type of 상병처치, they felt that extraction was inexpensive for dental hard tissue diseases. Regarding pump and periapical diseases, pulp treatment that is the most common one for these types of diseases didn't cost a lot, and in the event of gingival and peridontal diseases, extraction was not expensive.
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The Exposure Amount of Paraben from Commercial Toothpaste
Geum-Sun Ahn,Yong-Duk Park,Su-Min Yoo 대한예방치과학회 2014 International Journal of Clinical Preventive Denti Vol.10 No.1
Objective: Parabens, which have cytotoxic activity, are widely used preservatives in personal care products. In this study, the exposure amounts of paraben during toothpaste usage were predicted by analyze the paraben concentration in commercial dentifrices using high-performance liquid chromatography. Methods: Commercial toothpaste from different manufacturer were extracted in methanol, diluted with distilled water to make concentration 0.5 mg/L. Four parabens (methylparaben, ethylparaben, propylparaben, and butylparaben) in toothpaste samples were separated by high-performance liquid chromatography using C18 column and 50% acetonitrile at 20oC, then detected at ultraviolet 256 nm. Results: The analytical method showed good precision and accuracy. Any parabens weren’t detected in toothpastes from one manufacturer, and were detected in toothpastes from other two manufacturer except ethylparabens. The exposed total parabens per one brushing was maximally 1.8 mg. Conclusion: The amount of parabens from toothpaste was predicted to be insignificant compared to other routes (cosmetics, foods); however, it is need to minimize the use of parabens in toothpaste.
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안금선 ( Geum Sun Ahn ),김효정 ( Hyo Jeong Kim ) 한국치위생학회(구 한국치위생교육학회) 2011 한국치위생학회지 Vol.11 No.5
Objectives: The purpose of this study was to examine students`difficulties in the process of oral radiography practice, to raise awareness of the importance and necessity of oral radiography and decipher, and to provide some information on effective ways of oral radiography practice. Methods: The subjects in this study were 285 dental hygiene students at K college, who included 153 sophomores and 132 graduates-to-be from June to November, 2010. Results: 1. The parts of the anatomy structure that they found it most difficult to decipher were maxillary molar(25.3%) and lower molar(22.1%). 2. They made during oral radiography was an improper film positioning( 35.1%). 3. The part of bisecting technique was adjusting vertical and horizontal angles(53.0%). 4. The part of paralleling technique was positioning XCP in the oral cavity(44.2%). 5. The part of bite-wing technique was adjusting vertical and horizontal angles(38.2%). 6. The part of occlusion technique was positioning film and tube head(36.5%). 7. The part of panorama technique was finding out program setting(42.5%). Conclusions: The findings of the study indicated that in terms of anatomy structure decipher, it`s especially difficult to decipher maxillary molar and lower molar, and that film positioning was difficult to do in the process of oral radiography. What difficulties they faced in applying each kind of oral radiography techniques and which part of the oral cavity they found it hard to radiograph were analyzed as well in this study. Given the findings of the study, more intensive practice is required to help students to acquire accurate oral radiography techniques to ensure their successful job performance in the future. (J Korean Soc Dent Hygiene 2011;11(5):783-790)
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( Soon Sun Kim ),( Jung Woo Eun ),( Ji-hye Choi ),( Hyun Goo Woo ),( Hyo Jung Cho ),( Hye Ri Ahn ),( Chul Won Suh ),( Geum Ok Baek ),( Sung Won Cho ),( Jae Youn Cheong ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: We aimed to identify novel single nucleotide variant (SNV) in circulating tumor DNA (ctDNA) in patients with hepatocellular carcinoma (HCC). Methods: Deep sequencing of plasma-derived ctDNA was performed using a panel of 2,924 SNVs in 69 genes from 59 patients with HCC. Validation of frequent SNVs (MLH1, STK11, PTEN, and CTNNB1) identified in ctDNA was conducted using droplet digital PCR (ddPCR) in 62 patients. Additionally, the presence of MLH1 and STK11 SNVs was determined in HCC tissues from 37 patients. Association between the presence of SNVs or the amount of ctDNA and clinical parameters and prognosis was determined in 107 patients. Results: In 33/59 (55.9%) patients, at least one somatic mutation was detected using targeted deep sequencing of ctDNA. Among 25 SNVs in 12 genes, SNVs in KIT (17%), MLH1 (13%), STK11 (13%), PTEN (9%), and CTNNB1 (4%) were the most frequently observed. Using ddPCR, SNVs were detected in 22/62 (35.5%) patients with a frequency of 19% for MLH1 (chr3:37025749_T>A), 11% for STK11 (chr19:1223126_C>G), 8% for PTEN (chr10:87864461_C>G), and 0% for CTNNB1 (chr3: 41224610_C>T). MLH1 and STK11 SNVs in ctDNA were also detected in DNA derived from tumor tissues from all patients. The combination of the presence of MLH1 SNVs and increased ctDNA predicted overall survival in 107 patients. Conclusions: MLH1 SNV (chr3:37025749_T>A) detection in ctDNA is feasible and can be used to detect somatic mutations in HCC. Furthermore, the MLH1 SNV in ctDNA predicts prognosis with or without determining the amount of ctDNA in patients with HCC.
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( Hye Ri Ahn ),( Geum Ok Baek ),( Moon Gyeong Yoon ),( Chul Won Seo ),( Suna Sung ),( Ju A Son ),( Jung Woo Eun ),( Jae Yeon Cheong ),( Hyo Jung Cho ),( Soon Sun Kim ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: Hepatocellular carcinoma (HCC) is the one of the most common cancers and lethal diseases in the world. Wiskott-Aldrich Syndrome Protein Family Member 2 (WAVE2) overexpression overexpression is reported in HCC. However, the regulation mechanism of WAVE2 and its effect on HCC progression is not well-known. We aimed to explore WAVE2 regulation mechanism through methylation study and WAVE2 role on HCC progression through in vitro study. Methods: Methylation status of WAVE2 was determined through profiling of promoter-region DNA methylation in HCC from The Cancer Genome Atlas (TCGA) data. Validation was performed with bisulfite-specific PCR sequencing and methylation-specific PCR analysis in 20 pairs HCC tissues with corresponding non-cancerous tissues. Targeted inactivation of WAVE2 using siRNA was performed in HCC cell lines and cell growth and proliferation were examined. Results: WAVE2 was significantly overexpressed in HCCs compared to non-tumor tissues and associated with poor prognosis in overall survival and disease-free survival of patients in TCGA data. Also, we found inverse correlation between DNA methylation and gene expression of WAVE2, and WAVE2 was significantly hypomethylated in human HCC compared to non-tumor. Targeted inactivation of WAVE2 suppressed cell growth and proliferation of HCC cells, and reduced the metastatic potential of HCC cells by selectively modulating epithelial mesenchymal transition regulatory proteins. Conclusions: We observed that WAVE2 is significantly overexpressed and hypomethylated in HCC. Also, WAVE2 up regulation is associated with poor prognosis in HCC patients. WAVE2 activation might be one of the key mechanisms during liver tumorigenesis and can be a candidate of therapeutic target for HCC.
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안금선,김효정,Ahn, Geum-Sun,Kim, Hyo-Jeong 한국치위생학회 2011 한국치위생학회지 Vol.10 No.2
Objectives : The purpose of this study was to examine students' difficulties in the process of oral radiography practice, to raise awareness of the importance and necessity of oral radiography and decipher, and to provide some information on effective ways of oral radiography practice. Methods : The subjects in this study were 285 dental hygiene students at K college, who included 153 sophomores and 132 graduates-to-be from June to November, 2010. Results : 1. The parts of the anatomy structure that they found it most difficult to decipher were maxillary molar(25.3%) and lower molar(22.1%). 2. They made during oral radiography was an improper film positioning(35.1%). 3. The part of bisecting technique was adjusting vertical and horizontal angles(53.0%). 4. The part of paralleling technique was positioning XCP in the oral cavity(44.2%). 5. The part of bite-wing technique was adjusting vertical and horizontal angles(38.2%). 6. The part of occlusion technique was positioning film and tube head(36.5%). 7. The part of panorama technique was finding out program setting(42.5%). Conclusions : The findings of the study indicated that in terms of anatomy structure decipher, it's especially difficult to decipher maxillary molar and lower molar, and that film positioning was difficult to do in the process of oral radiography. What difficulties they faced in applying each kind of oral radiography techniques and which part of the oral cavity they found it hard to radiograph were analyzed as well in this study. Given the findings of the study, more intensive practice is required to help students to acquire accurate oral radiography techniques to ensure their successful job performance in the future.
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