Synergistic Enhancement of the Strength-Ductility for Stir Casting SiCp/2024Al Composites by Two-Step Deformation

Fu‑xiang Cao,Kun‑kun Deng,Cui‑ju Wang,Kai‑bo Nie,Wei Liang,Jian‑feng Fan 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.12

The 10 μm 10 vol% SiCp/2024Al composites sheet was successfully fabricated by semi-solid stir casting followed withtwo-step deformation (extrusion and rolling). The two-step thermal deformation solves the sheet rolling formability of theSiCp/2024Al composites produced by stir casting. Compared with the SiCp/2024Al composites prepared by traditional powdermetallurgy, this paper innovatively studied the synergistic enhancement between CuAl2phase and SiCpon the mechanicalproperties. The result shows that the two-step deformation can significantly improve the uniformity of the distribution of SiCpand CuAl2phases. At the same time, the average size of the SiCpand CuAl2phase decreases after the two-step deformation. During the hot extrusion, SiCphas an obvious hindrance to the refinement of the CuAl2phase. Moreover, the SiCp/2024Alcomposites sheet exhibits excellent yield strength (295 MPa), ultimate tensile strength (489 MPa), and elongation (10.42%). The performance improvement of SiCp/2024Al after two-step thermal deformation is mainly attributed to the improvedinterface bonding strength of SiCp-2024 Al matrix, the refined SiCpand the more uniform distribution of SiCp.

한·중 파생 신어의 분포·의미적 대조 연구 - 2010년~2020년 신어를 중심으로 -

푸량 ( Fu¸ Liang ) 연세대학교 언어정보연구원 2021 언어사실과 관점 Vol.54 No.-

This study aims to examine the distribution changes of Korean and Chinese derivative neologisms over the past 10 years from a short-term diachronic perspective, and to contrast the semantic features of productive affixes. In terms of distribution, both Korean and Chinese derivative neologisms showed an overall decline, and the increase in the number of phrase neologisms is the main reason. In the process of decreasing, the derivative neologisms of Chinese had a comparatively distinct change point and the descending width was larger. This is related to some affixes, which are most productive among the derivative neologisms of Chinese. In terms of meaning, this paper compared the semantic features of the productive affixes of Chinese and Korean neologisms. Prefixes in Korean neologisms often indicate the state or degree of the word, and often contain negative meanings. By comparison, prefixes in Chinese neologisms mostly indicate ways of doing things and are neutral in meaning. Most of the suffixes in Korean and Chinese neologisms are related to ‘people’, but there are differences in semantic categories and detailed meanings. Among the productive suffixes, Korean has suffixes related to ‘region and place’, while Chinese has suffixes referring to ‘service platform or system’.

4000年前全球降温事件与中国五帝联盟的诞生

付希亮(Fu, Xi–liang),최창원 중국학연구회 2014 중국학연구 Vol.- No.68

Archaeology of Neolithic era proved that Chinese civilization originated diversely and developed independently. Archaeologist Su Bingqi divided Neolithic culture into six parts: Yangshao, Hongshan, Liangzhu, Dawenkou, Majiayao and Qujialing cultural districts. By the Longshan culture period, social development of each cultural district had reached to a very high level. Global cooling and flood, drought triggered by it in 4200-4000 ago brought enormous disaster to five cultural districts except for Yangshao. The tribes in these five districts started to migrate to the middle reaches of the Yellow river. Finally, a huge tribal alliance-the five emperors’ league was established through mutual compromise. Then Chinese civilization changed form “starring night” to “the YellowRivercivilization”stage. 4200—4000前的全球降温及其引发的洪水、旱灾给 仰韶之外的五大文化区带来了巨大灾难,这些地区居住的部落向黄河中游地区迁徙。这些部落与 居住在黄河中游原住部落之间爆发了冲突,最终通过相互妥协得到了解决,建立了一个庞大的部落联盟,这就是五帝联盟。中国文明 由此由“漫天星斗”转为“黄河文明”阶段。

T Lymphocyte Subsets and Cytokines in Rats Transplanted with Adipose-Derived Mesenchymal Stem Cells and Acellular Nerve for Repairing the Nerve Defects

Liang-fu Jiang,Ou Chen,Ting-gang Chu,Jian Ding,Qing Yu 대한신경외과학회 2015 Journal of Korean neurosurgical society Vol.58 No.2

Objective : The aim of this study was to explore the immunity in rats transplanted with adipose-derived mesenchymal stem cells (ADSCs) and acellular nerve (ACN) for repairing sciatic nerve defects. Methods : ADSCs were isolated from the adipose tissues of Wistar rats. Sprague-Dawley rats were used to establish a sciatic nerve defect model and then divided into four groups, according to the following methods : Group A, allogenic nerve graft; Group B, allograft with ACN; Group C, allograft ADSCs+ACN, and Group D, nerve autograft. Results : At the day before transplantation and 3, 7, 14, and 28 days after transplantation, orbital venous blood of the Sprague-Dawley rats in each group was collected to detect the proportion of CD3+, CD4+, and CD8+ subsets using flow cytometry and to determine the serum concentration of interleukin-2 (IL-2), tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) using enzyme-linked immunosorbent assay (ELISA). At each postoperative time point, the proportion of CD3+, CD4+, and CD8+ subsets and the serum concentration of IL-2, TNF-α, and IFN-γ in group C were all near to those in group B and group D, in which no statistically significant difference was observed. As compared with group A, the proportion of CD3+, CD4+, and CD8+ subsets and the serum concentration of IL-2, TNF-α, and IFN-γ were significantly reduced in group C (p<0.05). Conclusion : The artificial nerve established with ADSCs and ACN has no obvious allograft rejection for repairing rat nerve defects.

Anthocyanins in ‘Cabernet Gernischet’ (Vitis vinifera L. cv.) Aged Red Wine and Their Color in Aqueous Solution Analyzed by Partial Least Square Regression

Fu-Liang Han,Shou-Mei Jiang,Jian-Jun He,Qiu-Hong Pan,Chang-Qing Duan,Ming-Xia Zhang 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.3

Anthocyanins are considered one of the main color determinants in aged red wine. The anthocyanins in aged red wine made from ‘Cabernet Gernischet’ (Vitis vinifera L. cv.) grape were investigated by high performance liquid chromatography- electronic spray ionization- mass spectrometry (HPLC-ESI-MS) and their color presented in aqueous solution were evaluated using partial least square regression (PLS). The results showed that there were 37 anthocyanins identified in this wine, including 22 pyranoanthocyanins. The analysis of PLS indicated that different anthocyanins showed distinct color values: malvidin 3-O-(6-O-acetyl)-glucoside-4-vinylguaiacol (Mv3-acet-glu-vg) presented the highest color values, while malvidin 3-O-glucoside (Mv3-glu) showed least. Among the free non-acylated anthocyanins, peonidin 3-Oglucoside (Pn3-glu) showed the highest color values; the coumarylated anthocyanins presented higher color values than their corresponding acetylated anthocyanins and parent anthocyanins; pyranoanthocyanins presented also higher color values than their original anthocyanins; the color of anthocyanins depended on their structure. This work will be helpful to reveal evolution in aged red wine.

An Integrated Nomogram Combining Clinical Factors and Microtubule-Associated Protein 1 Light Chain 3B Expression to Predict Postoperative Prognosis in Patients with Intrahepatic Cholangiocarcinoma

Liang Chen,Hongyuan Fu,Tongyu Lu,Jianye Cai,Wei Liu,Jia Yao,Jinliang Liang,Hui Zhao,Jiebin Zhang,Jun Zheng,Yingcai Zhang,Yang Yang 대한암학회 2020 Cancer Research and Treatment Vol.52 No.2

Purpose Microtubule-associated protein 1 light chain 3B (LC3B) serves as a key component of autophagy, which is associated with the progression of carcinoma. Yet, it is still unclear whether LC3B is also an independent risk factor for intrahepatic cholangiocarcinoma (ICC). We aim to explore the predictive value of LC3B on prognosis of ICC, and to establish a novel and available nomogram to predict relapse-free survival (RFS) and overall survival (OS) for these patients after curative-intent hepatectomy. Materials and Methods From August 2004 to March 2017, 105 ICC patients were eligibly enrolled in the Third Affiliated Hospital of Sun Yat-sen University. Preoperative clinical information of enrolled patients was collected. Expression LC3B in the ICC specimen was detected by immunohistochemistry. Results The 5-year RFS and OS in this cohort were 15.7% and 29.6%, respectively. On multivariate Cox regression analysis, independent risk factors for 5-year OS were cancer antigen 125, microvascular invasion, LC3B expression and lymph node metastasis. Except for the above 4 factors, neutrophil/lymphocyte ratio and tumor differentiation were independent factors for 5-year RFS. The area under the curve of nomograms for OS and RFS were 0.820 and 0.747, respectively. Conclusion The nomograms based on LC3B can be considered as effective models to predict postoperative survival for ICC patients.

T Lymphocyte Subsets and Cytokines in Rats Transplanted with Adipose-Derived Mesenchymal Stem Cells and Acellular Nerve for Repairing the Nerve Defects

Jiang, Liang-fu,Chen, Ou,Chu, Ting-gang,Ding, Jian,Yu, Qing The Korean Neurosurgical Society 2015 Journal of Korean neurosurgical society Vol.46 No.5

Objective : The aim of this study was to explore the immunity in rats transplanted with adipose-derived mesenchymal stem cells (ADSCs) and acellular nerve (ACN) for repairing sciatic nerve defects. Methods : ADSCs were isolated from the adipose tissues of Wistar rats. Sprague-Dawley rats were used to establish a sciatic nerve defect model and then divided into four groups, according to the following methods : Group A, allogenic nerve graft; Group B, allograft with ACN; Group C, allograft ADSCs+ACN, and Group D, nerve autograft. Results : At the day before transplantation and 3, 7, 14, and 28 days after transplantation, orbital venous blood of the Sprague-Dawley rats in each group was collected to detect the proportion of $CD3^+$, $CD4^+$, and $CD8^+$ subsets using flow cytometry and to determine the serum concentration of interleukin-2 (IL-2), tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$) and $interferon-{\gamma}$ ($IFN-{\gamma}$) using enzyme-linked immunosorbent assay (ELISA). At each postoperative time point, the proportion of $CD3^+$, $CD4^+$, and $CD8^+$ subsets and the serum concentration of IL-2, $TNF-{\alpha}$, and $IFN-{\gamma}$ in group C were all near to those in group B and group D, in which no statistically significant difference was observed. As compared with group A, the proportion of $CD3^+$, $CD4^+$, and $CD8^+$ subsets and the serum concentration of IL-2, $TNF-{\alpha}$, and $IFN-{\gamma}$ were significantly reduced in group C (p<0.05). Conclusion : The artificial nerve established with ADSCs and ACN has no obvious allograft rejection for repairing rat nerve defects.

Therapeutic inhibition of SGK1 suppresses colorectal cancer

Xuchun Liang,Chunling Lan,Guanming Jiao,Wencheng Fu,Xuesha Long,Yu An,Kejin Wang,Jinzhe Zhou,Ting Chen,Yongqin Li,Jiahong Xu,Qi Huang,Bin Xu,Junjie Xiao 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-

Colorectal cancer (CRC) is one of the leading causes of death worldwide. Thus, the development of new therapeutic targets for CRC treatment is urgently needed. SGK1 is involved in various cellular activities, and its dysregulation can result in multiple cancers. However, little is known about its roles and associated molecular mechanisms in CRC. In present study, we found that SGK1 was highly expressed in tumor tissues compared with peri-tumor samples from CRC patients. In vitro experiments revealed that SGK1 overexpression promoted colonic tumor cell proliferation and migration and inhibited cell apoptosis induced by 5-fluorouracil (5-FU), while SGK1 shRNA and inhibitors showed the inverse effects. Using CRC xenograft mice models, we demonstrated that knockdown or therapeutic inhibition of SGK1 repressed tumor cell proliferation and tumor growth. Moreover, SGK1 inhibitors increased p27 expression and promoted p27 nuclear accumulation in colorectal cancer cells, and p27 siRNAs could attenuate the repression of CRC cell proliferation induced by SGK1 inhibitors. Collectively, SGK1 promotes colorectal cancer development via regulation

재정적 위기가 중국의 재정 개혁에 미치는 영향

Yu Liang Fu 단국대학교 사회과학연구소 2009 공공정책과 국정관리 Vol.3 No.1

The Influence of the Attributes of Electric Vehicles on Brand Image, Consumer Attitude, and Purchase Intention: Focusing on the Moderating Effects of ESG Management

Zhenyang Fu(Zhenyang Fu),Jin-Sup Jung(Jin-Sup Jung),Sijian Niu(Sijian Niu),Liang Yi(Liang Yi) The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.3

Purpose - Direct and indirect factors affecting purchase of electric vehicles, and potential factors affecting purchase intention are studied. The effects of electric car attributes (functionality, economy, design, safety), brand image, and consumer attitude on electric car purchase intention was examined. The mediating effect of brand image and consumer attitude is examined. In addition, the moderating effect of ESG management between attributes and the brand image of electric vehicles was examined. Design/Methodology/Approach - Electric vehicle attributes were set as independent variables, and purchase intentions were set as dependent variables. In addition, the mediating effect of brand image and consumer attitude and the moderating effect of ESG management were considered. An empirical study was conducted targeting Chinese consumers, and multiple regression analysis was used as the research methodology. Findings - The attributes of electric vehicles (functionality, economy, design, safety) had a significant effect on brand image and purchase intention. Among the attributes of electric vehicles, economic feasibility, design, and safety had a significant positive (+) effect on consumer attitudes. Brand image and consumer attitude showed a positive (+) mediating effect between electric vehicle attributes and purchase intention. Further, the moderating effect of ESG management showed a positive moderating effect only between functionality and brand image. Research Implications - The study provides academic, practical, and policy implications for establishing an electric vehicle marketing strategy in the Chinese market. In particular, it is meaningful to marketing and distribution strategies for foreign companies, including Korean companies that wish to advance into China.