항코린에스테라제 독성에 대한 Histamine길항제의 효과

박은희,양근해,김오션 숙명여자대학교 약학연구소 1997 약학논문집-숙명여자대학교 Vol.13 No.-

This study was designed to examine the effects of antihistamines on the toxicity of neostigmine, a reversible cholinesterase inhibitor, in mice. Diphenhydramine and promethazine pretreatment increased the LD_(50) value of neostigmine by 2.15- and 3.65-fold, respectively. They also increased the onset times of toxic manifestations such as whole body tremor, loss of righting reflex and death. However, chlorcyclizine, chlorpromazine, i antazoline, chlorpheniramine and cimetidine pretreatment did not reduce the toxicities of neo-stigmine.

연마기구에 따른 심미 치아 수복재료의 표면 거칠기에 관한 비교 연구

박은혜,양규호,최남기 大韓小兒齒科學會 2003 大韓小兒齒科學會誌 Vol.30 No.3

소아치과 임상에서 자주 사용하고 있는 심미 수복재료는 마무리와 연마 과정을 통해 내구성과 심미성이 향상된 수복물을 얻을 수 있다. 본 연구에서는 수복재료 종류에 따른 연마기구의 적합성과 사용된 연마기구 간의 효율성을 비교하고자 하였다. Z250(3M, USA), Helionolar(Ivoclar Vivadent, USA), Dyract AP(Dentsply, USA), Fuji Ⅱ LC(GC, Japan)를 이용하여 시편을 제작하고, 연마기구의 Enhance(Ivoclar Vivadent, USA), Sof-Lex(3M, USA), CompoSite(Shoufu, Japan)를 적용하여 연마하였다. 각 제품마다 제작된 시편 중에 어떠한 연마 과정도 거치지 않은 5개의 시편을 대조군으로 사용하였다. 이 시편들의 표면 거칠기(R_a value, ㎛)를 측정하고, 주사전자현미경으로 관찰하여 다음과 같은 결과를 얻었다. 1. 수복재료에 따른 표면 거칠기를 비교한 결과 Z250이 가장 낮은 표면 거칠기를 나타냈으나 다른 수복재료와 비교하여 유의한 차이는 없었다(p>0.05). 2. 네 가지 수복재료는 대조군에서 가장 평활한 표면을 얻었고, 모든 연마 과정은 표면 거칠기를 증가시켰다. 3. 세 가지 연마기구 중 Sof-Lex가 가장 평활한 표면을 형성하였으며, Sof-Lex와 Enhance에 의한 표면 거칠기는 유의한 차이를 보였다(p<0.05). 4. 주사전자현미경 관찰 시 네 가지 수복재료의 대조군은 실험군에 비해 균일한 표면을 나타냈다. Proper finishing and polishing of tooth restorations enhance the esthetics and the longevity of the restored tooth. The aims of this study were to identify an appropriate polishing system for each esthetic restorative material(Z250, Heliomolar, Dyract AP, Fuji Ⅱ LC), and to compare the efficiency of polishing systems(Enhance, Sof-Lex, CompoSite), The control group remains untouched. The results were as follows: 1. There was no significant difference of surface roughness among the materials, while a roughness value of Z250 was the lowest of all. 2. The smoothest surface was produced by Mylar sheet on all materials. The polishing procedures, however, increased a roughness value. 3. The smoothest surfaces were produced by Sof-Lex, and there was significant difference of surface roughness between Sof-Lex and Enhance systems. 4. The smoothest surfaces on the control group showed many scratches after the polishing procedures in the SEM findings.

폴리아민이 흰쥐 복재신경 재생에 미치는 영향 - Ⅰ. 수초신경섬유의 직경과 수초 두께의 변화

이종은,문혜원,이원택,박경아 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

동거형태에 따른 젊은 남자성인의 식행동과 건강관련 행동의 차이

박영숙,장지혜,임은희,한재라 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.2

A survey was performed to 250 male young men who were living alone and shared living with friends in Chungnam province. Their average age was 22.6 years old, height was 171.8 cm, weight was 65.6 kg and BMI was 22.2 Comparing the prevalence of drinking, smoking and exercise, there were significantly different between living alone subjects and shared-living ones. The main value toward eating/meals was for hungry soultion. And we found many significant differences by living with or without companion. When young men living without companions, they shouved to be more in regular mealtimes, no-skipped meals, breakfast eating, adequate food amounts, eating-outs, etc. and to be less in pleasant mealtimes, various foods, snacking and especially late snacks. The good food intake pattern were highly scored in the alone-living group than the shared-living group, whereas the bad food intake pattern were also highly scoued in the alone-living group than the other. The latter might be due to the more food exposures because of companions. These findings could conclude that dietary behaviors of the young living alone were evaluated as good enough.

백내장 수술환자의 진료결과에 미치는 요인 : 사전 연구를 중심으로 Pilot study

박은철,홍영재,임승정,강형곤,최윤정,김한중,조우현,손명세 한국의료QA학회 1998 한국의료질향상학회지 Vol.5 No.1

Backgroud : This study is to identify preoperative patient characteristics associated with a lack of improvement on one or more measures perioperatively, postoperative 3-4 months, and postoperative 12 months. Methods : For the assessment, prospective study was performed with 92 patients who had undergone either one eye or both eye cataract surgery by 3 ophthalmologists practicing at a university hospital. The criteria of improvement were (1) Snellen visual acuity, (2) a cataract-related symptom score(possible range: 0. 0 of 6 symptoms present or bothersome, to 18. all 6 symptoms very bothersome), and (3) VF-14 score - a measure of functional impairment in patient with cataract - (possible range: 0, inability to perform any of the applicable activities, to 100, no difficulty in performing any of the applicable activities). Results : Although 14 patients (15.2%) failed to improve on one or more of the outcome measures assessed, no one failed to improve on all three measures. Both eyes of surgery than one eye, preoperative cataract symptom score of 1-4, 5 or higher than 0 were associated independently with the increased likelihood of improvement (odds ratio 8.95, 7.16, 8.87 respectively). And the preoperative level of Snellen visual acuity was not associated with the likelihood of improvement Conclusion : We conclude that specific preoperative characteristics (both eyes, cataract symptom score) are independent predictors of patient outcome after cataract surgery,

네오스트그민 독성에 대한 디펜히드라민 및 프로메사진의 효과

박은희,양근해,전민정 숙명여자대학교 약학연구소 1998 약학논문집-숙명여자대학교 Vol.14 No.-

This study was designed to examine the effects of diphehydramine and promethazine on the toxic manifestation of neostigmine. It was found that diphenhydramine and promethazine increase acetylcholinesterase activity in liver of mice. When diphenhydramine and promethazine was treated before administration of neostigmine, it significantly extend the onset latency in the signs of toxicities which were characteristically produced by neostigmine and it also prevented lethality in all of the animals.

백금(Ⅳ)착제가 염증에 미치는 영향

박은희,양근해,김선희 숙명여자대학교 약학연구소 1993 약학논문집-숙명여자대학교 Vol.9 No.-

The platinum complex, PtCl₄(2-CEen), was previously synthesized and shown to have anti-tumor activity. In the present study, the anti-inflammatory activity of platinum complex, PtCl₄(2-CEen), was investigated utilizing carrageenin-induced edema in rats. Its anti-inflammatory activity was confirmed with significance when a dose of lOmg/kg was intraperitoneally administered.

韓國人 學生의 腦機能 優勢(Cerebral Dominance)와 손잡이(Handedness)의 傾向

박창근,김은희,박매자,배용철,홍해숙,조희중,주강 慶北大學校 醫科大學 1990 慶北醫大誌 Vol.31 No.4

This study was investigated the effects of specialization of brain functions, the distribution of handedness and the correlation between cerebral dominance and handedness. This was surveyed with the samples of 1,302 Korean boys and girls attending in junior high school and senior high school, residing in Taegu city. In this study, Alfred W. Munzert's questionnaire and Tames Bliss & Joseph Morella's questionnaire were used as the instrument for assessing the thend of cerebral dominance and handedness. The results obtained were as follows: Out of the total number of 1,302 examined, 73.7% of them were regarded as right hemisphere dominant type and 12.6% of them were regarded as left hemisphere dominant type. In right hemisphere dominant type, students of junior high school were higher incidence than senior high School. In bilateral and left hemisphere dominant type, students of senior high school were higher incidence than junior high school. In right handers most of them were right hemisphere dominant type. In left handers, most of them were right hemisphere dominant type and the incidence of boys were higher than girls.

외음부와 자궁에 생긴 평활근종 1예

박혜인,이해혁,김태희,김정식,남계현,이권해,고은석 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

The leiomyomas of the vulva are rare benign tumors the incidence is 0.024%~0.55% in women. There are no relationship between leiomyomas of the vulva and uterus. But there are some reports that leiomyomas of the vulva and uterus simultaneously. The leiomyomas of the vulva present without symptoms and excision with biopsy is treatment of choice. Tumors of the gynecological apparatus may present without symptoms, or they may mimic other common gynecological conditions. Because of this, any vulva mass must be considered cautiously. We reported this case with a brief review of the concerned literatures.

공장 업무자동화를 위한 분산처리 시스템의 개발

박두순,공용해,오동익,정종석,오은숙 호서대학교 반도체제조장비국산화연구센터 2000 학술대회 자료집 Vol.2000 No.1

(주)한길은 콘크리트 2차 가공 업체로서, 주로 벤치플륨, 맨홀, 수로관, PC암거박스 등을 생산하고 있는 중소기업이다. 이 업체는 제품의 특수성과 생산 시설의 규모로 인하여 납품 계약 후에 미리 적정량을 생산하여 재고로 보유하면서 제품을 적기에 납품해야 한다. 그러나 현재 입고, 재고, 출고 관리 등의 업무전산화가 이루어져 있지 않을 뿐만 아니라 생산, 저장, 관리가 동일한 장소와 더불어 지역적으로 분리된 곳에서 이루어지고 있어 정보관리에 많은 어려움을 겪고 있다. 이에 본 연구에서는 근거리 네트워크와 전화접속 네트워크를 혼합한 하이브리드 형태의 분산 환경 시스템을 구축하여 경제적으로 가장 최적인 네트워크 솔루션을 제공하고, 이를 바탕으로 하는 입고, 재고, 출고 관리 시스템과 기본적인 회계 등의 전산 업무를 개발하여 업체의 생산성 및 경쟁력 향상을 도모하고자 한다.