생활체육참여자의 여가활동 유형이 생활만족에 미치는 영향

김의영,김의영,김영숙,윤대중,이병기 龍仁大學校 體育科學硏究所 2002 體育科學硏究論叢 Vol.12 No.1

This research is designed to make a comparative analysis of the types of leisure activities and the degree of and life satisfaction by demographic background variable and to present basic materials necessary for the development of programs for local policies on leisure in accordance with the local autonomous system with a view to determining the relationship between life satisfaction by type of leisure activity. The following are the findings. First, the survey failed to test a statistically significant difference between family member's mutual satisfaction, or the subordinate variable of age, job and health and general life satisfaction, or the subordinate variable of income. But there was a statistically significant difference in life satisfaction by gender, age, education, job, income and health at a level of 1 percent. Second, the survey on the influences of the types of leisure activities on leisure satisfaction and life satisfaction revealed that there was a statistically significant influences in all the subordinate variables of and life satisfaction.

성인간호학회지 논문(1989-2000)의 내용과 경향 분석

서문자,김소선,송미순,이명선,오의금,신경림,김옥수,이숙자,이영자,오효숙,정재심,김철규 성인간호학회 2001 성인간호학회지 Vol.13 No.4

"Journal of Korean Academy of Adult Nursing" has been published since 1989 and more than 330 articles have been published up 2000. We reviewed all the articles published in this journal to analyze the contents and trend of published articles and to find out the way of improvement both in quantity and quality of studies in this area. The results are as follows : 1) Ninety percent of articles were quantitative studies. Experimental design was used in 16.1% and quasi-experimental design was adapted in 73.6% of articles. Qualitative research were 10.3% of total articles reviewed. 2) Only 5.1% of articles described theoretical framework and 73.6% of experimentally designed articles included research hypotheses. 3) Among experimental studies, only one was true experimental studie design. Eighty nine point three persent had descriptive survey method among non-experimental studies. Amog the thirty four qualitative studies, phenomenologic(73.5%), grounded theory(14.7%), and ethnographic (11.8%) design were used. 4) Most of research subject were patients and few healthy people, healthcare worker, and patient family. 5) Psychosocial data collection method which used questionnaire were 53.7% and interview. physical measurement, observation were used in 22.8%. 8.2% 5.4% of articles respectively. 6) Total number of keywords were 692, and average number of key words per article was 2.2. Health-related keyword was the most frequently used according to four metaparadigm of nursing (human, health, nursing, and environment). Environment related keyword was rarely appeared. The number and quality of nursing research in "Journal of Korean Academy of Adult Nursing" have been improved continuously. It is difficult to find out special trend or characteristics which is unique in this journal because of relatively short history of adult nursing studies. This review study was performed to analyze adult nursing studies only in the view of quantitative aspect, but it is needed to analyse qualitatively to find philosophical or theoretical trend in nursing.

마우스 상피세포의 일차배양시 배양양상과 최적조건에 관한 연구

김의숙,박선화,전용혁 고려대학교 의과대학 1992 고려대 의대 잡지 Vol.29 No.2

This study was attempted to compare the characteristics of primary culture of mouse epithelial cells and to determine the effective seeding density for confluency on two substrates. The dispersed single epithelial cells were cultured on culture dish coated with type Ⅲ collagen and culture slide. The culture conditions were adjusted to 3 DMEM:1 Fl2 media with 10% FBS, 37℃ temperature. 5% CO₂ air and pH 7.2-7.4 but the seeding density was changed within 1×10⁴-7×10^5 cells / ㎠ substrate. The results were as follows: 1. The characteristics of cultured cells were very similar in the collagen coated dish-used group and the culture slide-used group. The proliferation, stratification, keratinization and desquamation processes were observed like those in vivo. 2. There was a slight tendency to promote attachment. proliferation and differentiation on the collagen coated dish as compared with the culture slide. But it was not statistically significant. 3. The effective seeding density was in the ragne of 4-5×10^5 cells/㎠ substrate in both groups. But the time for cofluency was shortened accordings to rasing the seeding density.

江原道 東海岸 港浦口鄕土文化 論査報告:民俗信仰部門

金義淑 江原大學校 江原文化硏究所 1983 강원문화연구 Vol.3 No.-

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양구 <돌산령지게놀이>의 구조와 전승방안

김의숙 江原大學校 江原文化硏究所 1999 강원문화연구 Vol.18 No.-

Magnetic bead capture 를 이용한 염색체 띠 7q11, 7q22 에 위치한 cDNA 선별

김영수,김의숙,강윤희,전용혁,김현,박선화 고려대학교 의과대학 1997 고려대 의대 잡지 Vol.34 No.3

Recently, surmountable amounts of genes are being cloned and it has become neccessary to develope new techniques for discovering genes with known chromosomal location and their possible functions. We have developed one such a method and applied it to search for genes that may play a functional role during the development of the central nervous system. To observe the distribution of 18 weeks old fetal brain cDNAs on the chromosome, fluorescent in situ hybridization (FISH) was performed with biotin labeled 18 weeks old fetal brain cDNAs. Among the chromosome bands showing strong hybridization with the cDNAs, 7q11 and 7q22 were microdissected and amplified by PCR. Each band-specific probe pool was confirmed by FISH and band specific cDNAs were selected by magnetic bead capture method. Selected cDNAs were subcloned to plasmid vectors and the nucleic acid sequences were analysed. As a result 41 different clones from 7q11 and 43 different clones from 7q22 were obtained. They were categorized as 25 clones of well characterized genes, 22 clones showing low homology with known genes, 13 clones of simply registered uncharacterized human cDNAs, and 24 clones of unknown genes. From these results, it may be suggested that our technique is very useful to clone the genes expressed in the developing human brain with confirmed chromosomal location. In addition, this cloning technique can be used to discover the new genes related with neural development in combination with functional screening methods.

소화성 궤양에서 삼제 병합 요법의 저용량에 의한 Helicobacter pylori 제균률과 궤양 치유효과

김예리,박봉안,이재동,이종혁,김인숙,박형석,진춘조,김상윤,박의우 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Helicobacter pylori is the major cause of histologic chronic gastritis and is strongly associated with peptic ulcer disease, gastric cancer and lymphoma. Several recommendations for the management of the Helicobacter pylori infection have been developed. However, there has been no clear therapeutic regimen for the optimal treatment of Helicobacter pylori infection. This study was desinged to evaluate the eradication rate and the ulcer healing rate of the triple regimen with low-dose clarithromycin(0.5g/day) in peptic ulcer patients. Forty three patients with gastric ulcer(n=15) and duodenal ulcer(n=28) were enrolled. The patients were treated either with omeprazole 20mg b.i.d. amoxicillin 0.5g b.i.d. and clarithromycin 250mg b.i.d. (low-dose regimen group, n=29) or with omeprazole 20mg b.i.d., amoxicillin 1.0g b.i.d. and clarithromycin 0.5g b.i.d.(high-dose regimen group, n= 14) for 2 weeks. After 4 weeks, the patients were evaluated for the eradication of Helicobacter pylori and the healing of ulcer. And gastritis scores according to the Sydney system were evaluated before and after 4 weeks from the end of the triple regimen. There was no significant difference in the eradication rate and the ulcer healing rate between the low-dose regimen group, group and the high-does regimen group. In the low-does regimen group, the mean initial scores of chronic inflammation and activity were decreased after the eradication of Helicobacter pylori. In conclusion, the low-dose triple regimen is as effective as the high-dose triple regimen on the eradication of Helicobacter pylori and the ulcer healing rate in peptic ulcer disease.

페넴계 항생제 faropenem의 주요 임상분리세균에 대한 항균력

김재석,심영숙,김의종 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.4

목적 : Faropenem에 대한 국내 임상 분리 균주의 감수성 여부를 파악하기 위하여 임상 환자에서 흔히 분리되는 통성 혐기성 세균을 대상으로 최소억제농도(MIC_)를 측정하였으며, 대조항생제로는 amoxicillin과 cefaclor를 사용하여 그 결과와 서로 비교하였다. 방법 : 시험 균종은 2000년과 2001년 서울대학교병원 임상병리과로 세균배양이 의뢰된 혈액, 객담, 소변 등 임상검체에서 분리된 균주로서 임상환자에서 흔히 분리되는 통성 혐기성 세균 총 523주를 대상으로 하였다. 미국 임상검사표준화협회(NCCLS)에서 권장하는 방법에 따라 S. pneumoniae를 제외한 모든 균종은 한천희석법으로 MIC를 측정하였으며, S. pneumoniae는 microdilution broth법으로 MIC를 측정하였다. 결과 : Faropenem의 MIC는 전반적으로 비교약제에 비해 전반적으로 낮았다. E. coli, K. pneumoniae에 대한 MIC_(90)는 각각 1㎍/mL, 2㎍/mL이었으며, E. aerogenes, C. freundii, M. morganii는 4㎍/mL, E. cloacae는 8㎍/mL의 결과를 보였다. S. marcescens, A. baumanni의 MIC_(90)은 16㎍/mL, 32㎍/mL를 보였으며, P. aeruginosa와 S. maltophilia에서는 64㎍/mL 이상으로서 항균력이 없었다. S. aureus와 S. epidermidis에서는 메티실린 내성인 경우는 MIC_(90)이 64㎍/mL이상, 8㎍/mL이었다. 메티실린 감수성인 경우 0.125㎍/mL와 0.125㎍/mL이었다. E. faecalis와 E. faecium의 경우 MIC_(90)은 모두 64㎍/mL 이상을 보였으나, E. faecalis의 경우 MIC_(90)이 1㎍/mL로서 항생제 내성인 균주가 일부 포함되어 MIC_(90)이 높아진 것으로 보인다. S. pneumoniae의 경우 MIC_(90)은 0.5㎍/mL이었다. 결론 : Faropenem은 E. coli, K. pneumoniae에 대해서도 우수한 항균력을 보였다. 대조항생제에 비해 faropenem의 Enterobacteriacae에 대한 항균력은 높았다. 앞으로 faropenem에 대한 추가 연구가 필요하며, 특히 경구용 제재로 사용할 경우 약력학적 연구가 필요할 것으로 생각한다. Background : Minimal inhibitory concentrations (MICs) of facultative anaerobic bacteria isolated from several kinds of specimens of patients were determined for the in vitro susceptibility against the new oral penem, faropenern and compared with MICs of amoxicillin and cefaclor in Korea. Methods : Total 523 strains isolated from blood, sputum, or urine of patients at Seoul National University Hospital in 2000 and 2001 were examined by agar dilution or microdilution broth method according to the recommendations of National Committee for Clinical Laboratory Standards. Results : In general, the MICs of faropenem against major clinical isolates were lower than those of amoxicillin and cefaclor. MIC data showed that faropenern was active against Escherichia coli (MIC_(90)= 1㎍/mL) and Klebsiella pneumoniae (MIC_(90) = 2㎍/mL). The MICwS of Enterobacter aerogenes, Citrobacter freundii, Morganella morganii were 4 ㎍/mL. The MIC_(90)s of Enterobacter cloacae, Serratia marcescens, and Acinetobacter baumannii were relatively raised, 8 ㎍/mL, 16 ㎍/mL, and 32 ㎍/mL, respectively. Faropenem was not active against P. aeniginosa and S. maltophilia (MIC≥64 ㎍/mL). Although for MRSA MICs were high (MIC_(90)>64 ㎍/mL) compared with those for MRSE (MIC_(90) = 8 ㎍/mL), faropenern was active against methicillin-susceptible staphylococci (MIC_(90) = 0.125 ug/nmL). For Enterococcus faecalis and Enterococcus faecium, the MIC_(90)s were > 64 ㎍/mL. However, MICs of E. faecalis (MIC_(90) = 1 ㎍/mL) seems to be overestimated by including some resistant strains. The MIC_(90) of faropenern against S. pneumoniae was 0.5 ㎍/mL Conclusions : Faropenem was more active against E. coli, K. pneumoniae, and S. pneumoniae than reference drugs. The in vitro activity of faropenern was in many cases superior to those of amoxicillin and cefaclor. Pharmacokinetic study is needed, especially for the use of faropenern as an oral drug.

웹 기반 지리과 교수-학습 모형 개발

강창숙,장의선,김일기 한국사회과교육연구학회 2003 사회과교육 Vol.42 No.2

지금까지 인터넷을 활용하는 대부분의 지리교육 연구가 인터넷 환경인 웹 상의 정보를 지리과 교수-학습에 활용하는 정도에 그치는 경우가 많았으며, 대부분 교사 중심의 전통적인 교실 수업의 테두리 속에서 이루어져 왔다. 이들 연구들은 실제적인 교실 수업의 활용을 고려한다는 긍정적인 측면도 있지만, 인터넷이라는 새로운 매체가 가지고 있는 기능적인 특성을 고려하지 못했다는 비판이 이루어지고 있다. 이러한 문제의식에 기초하여, 웹의 특성과 지리 교육의 목적, 내용, 대상 등을 고려하여 웹 기반 지리과 교수-학습에 효과적인 모형을 탐색하고 실제를 개발했다. 문제중심학습 모형과 자원중심학습 모형에 해당하는 웹 기반 지리과 교수-학습 실제 사례를 통해 각각의 특성을 살펴본 결과, 웹 기반 지리과 교수-학습이 보다 효과적인 과정으로 이루어지기 위해서는 상호작용 환경의 구축 필요성을 인식하였다. 이에 학습자간, 학습자-자료간, 학습자-교사간의 상호작용 환경을 중심으로 하는 모형을 개발하고 적용하였다. Use of the Internet is proliferating rapidly, with mounting speculation as to the practical applications for teaching in education, yet few published or evaluated case studies are available in geography education characteristics. The purpose of this study is to review about Web-Based Instruction(WBD model and to develop WBI materials in geography, especially focused on Computer-Mediated Communication (CMC) technique and networking of the Internet. The results of this study are as follows. First, WBI application model suitable to geography are Problem-Based Learning(PBL) as the teaching plan model and Resource-Based Learning(RBL) as the learning information resources model. PBL with individual learning program and cooperative learning program which requires the learner to actively participate in solving given problems. RBL can be defined as a student centered learning mode in which the student learns from their own interaction with a wide range of databases found on the Web to solve problems. These models are commonly effective in improving the geographical thinking competence by WBI. Second, Learning purpose of students is achieved through the interaction and communication with others in the constructivist environment by Web. Also related research and studies show that CMC is the effective technique in improving learning achievement. Thus, the development of Web-Based geographical teaching-learning models has based on the CMC techniques such as learner-learner interaction, learner-content interaction, learner-instructor interaction. This materials established homepage for the geographical instruction board utilizing Web.

방사선사진의 인덱스-순서 분석을 통한 치아경조직의 탈염화 검출

박동현,박영호,김경숙,박정훈,이기자,최삼진,최용석,황의환,박헌국 대한구강악안면방사선학회 2009 Imaging Science in Dentistry Vol.39 No.2

Purpose : The purpose of this study was to develop the radiographic technique for detecting the demineralization which is known as indication of dental caries. Materials and Methods : This technique was based on the comparing of multiple radiographs which was irradiated by multiple X-ray spectra. For the meaningful comparing, the multiple radiographs were reconstructed to the dosimetrically consistent images using a standard material. The difference of resulting images of same target with multiple spectra represents the difference of response of material as regards the spectra. Results : We have found about 10% of demineralization of dental hard tissues particularly in the proximal region through the analyzing of differences. Conclusion : Most intriguing thing in this investigation was that the method to analyze difference shows us to an anatomic structure of dental hard tissues even if absolute values of optical density were excluded during the procedures.