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개에서 내측슬개골 탈구 등급에 따른 고관절 이상과의 상관관계에 대한 방사선학적 평가
이기자,박은정,권영항,최호정,이영원 한국임상수의학회 2013 한국임상수의학회지 Vol.30 No.4
This study was performed in 41 dogs with unilateral or bilateral medial patella luxation (MPL) and/or cranial cruciate ligament rupture (CCLR). These dogs were classified into 4 groups according to MPL grading system. Radiographic evaluation was performed for pelvis and stifle joint in the dogs. Norberg, inclination, quadriceps and femoral varus angle were measured and analyzed with MPL grading and the existence of cranial cruciate ligament rupture. The Norberg and inclination angle showed no differences between 4 grading groups and between CCLR and no CCLR groups. However, quadriceps and femoral varus angle were statistically different between grade 1, 2 and grade 3, 4 groups. They also have shown the statistical difference between CCLR and no CCLR group. Further studies for how these parameters affect the prognosis and the results of surgical treatment of MPL should be needed.
Computed Tomographic Evaluation of the Nasal Septum Deviation in Clinically Normal Dogs
이기자,이인,이희천,한우석,최호정,이영원 한국임상수의학회 2011 한국임상수의학회지 Vol.28 No.5
This study was performed to determine a comprehensive anatomic variation and deviation of the nasal septum in clinically normal dogs by use of computed tomography (CT). The nasal septum was evaluated in 36 shihtzu dogs and 16 beagle dogs. A degree of a septal deviation was evaluated by measuring a maximum angle and a distance of the septal deviation. The angle and distance of the septal deviation were significantly higher in shih-tzu dogs than in beagle dogs. There was no significant relationship between body weight and age and all measurements (angle and distance) in both breed dogs. Results of this study suggest that nasal septum deviation and its defect are observed on CT images of clinically normal dogs, especially in shih-tzu dogs.
Radiography and Computed Tomography in Four Dogs with Lung Lobe Torsion
이기자,최성진,김영환,정인성,최호정,이영원 한국임상수의학회 2013 한국임상수의학회지 Vol.30 No.5
This case study describes the imaging features of radiography and computed tomography (CT) in four small breed dogs with lung lobe torsion. The medical records, thoracic radiographs and CT images of four dogs with confirmed lung lobe torsion were retrospectively reviewed. Pleural effusion and increased lobar opacity/ density were seen on all CT and thoracic radiography in all four dogs. CT revealed narrowed/collapsed bronchus in all four dogs, while this was only appreciated on one thoracic radiography. The vesicular emphysema pattern was seen on four CT but only on three radiographic examinations. The specific findings of lung lobe torsion were vesicular emphysema and a narrowed/collapsed bronchus. These findings were more easily recognized on CT than with thoracic radiographs.
Diagnostic Imaging of Isolated Splenic Torsion in a German Shepherd Dog
이기자,정성목,최호정,이영원 한국임상수의학회 2011 한국임상수의학회지 Vol.28 No.6
A 5-year-old male German shepherd dog was presented with a 4 day-history of anorexia and depression. Abdominal radiographs showed a large soft tissue mass and loss of serosal detail. Ultrasonographs revealed splenomegaly with the lacy pattern parenchyma, perivenous hyperechoic region at the splenic hilum, and loss of splenic venous flow. Computed tomographic findings included the enlarged non-enhanced spleen except perivenous region at the splenic hilum and a whirled soft tissue mass at the splenic hilum. Exploratory laparotomy confirmed the diagnosis of splenic torsion. Ultrasonographic findings including lacy appearance, hyperechoic perivenous echogenicity and absence of splenic blood flow and CT findings including no or minimal enhancement of the spleen and a whirled appearance of splenic pedicle could be useful for diagnosing isolated splenic torsion in the dog.
이기자,최석근,오범석,박헌국,어윤혜,강성욱,최삼진,박정훈,임지은,홍경원,진현석 대한약리학회 2009 The Korean Journal of Physiology & Pharmacology Vol.13 No.1
During operations, neurosurgeons usually perform multiple temporary occlusions of parental artery, possibly resulting in the neuronal damage. It is generally thought that neuronal damage by cerebral ischemia is associated with extracellular concentrations of the excitatory amino acids. In this study, we measured the dynamics of extracellular glutamate release in 11 vessel occlusion (VO) model to compare between single occlusion and repeated transient occlusions within short interval. Changes in cerebral blood flow were monitored by laser-Doppler flowmetry simultaneously with cortical glutamate level measured by amperometric biosensor. From real time monitoring of glutamate release in 11 VO model, the change of extracellular glutamate level in repeated transient occlusion group was smaller than that of single occlusion group, and the onset time of glutamate release in the second ischemic episode of repeated occlusion group was delayed compared to the first ischemic episode which was similar to that of single 10 min ischemic episode. These results suggested that repeated transient occlusion induces less glutamate release from neuronal cell than single occlusion, and the delayed onset time of glutamate release is attributed to endogeneous protective mechanism of ischemic tolerance.
이기자,오이세,정성목,이희천,박성준,이영원,최호정 한국임상수의학회 2008 한국임상수의학회지 Vol.25 No.2
This study was performed to quantify the pleural effusion in radiography, ultrasonography and computed tomography(CT) and to evaluate and compare the usefulness of these methods. Normal saline of 10 ml/kg was infused into the pleural space until a final loading volume of 60 ml/kg body weight was reached in six Beagle dogs. The radiographic examination was performed for the detection and quantification of pleural effusion. On the ultrasonographic study, the maximum perpendicular distance was measured between the surface of the lung and the thoracic wall to evaluate pleural effusion. On the CT image, pleural effusion was evaluated as the perpendicular distance to the thoracic surface in the maximum pleural effusion volume on any transverse images with soft tissue window. Statistical analysis was performed using linear regression test. The volume of pleural effusion and measurements of radiography and ultrasonography had no statistical relationship. However, a significant correlation was identified between the volume of pleural effusion and the depth at right (r2= 0.715), left (r2= 0.745), and mean right and left depth (r2= 0.844) on the CT images. All of the thoracic radiographs, ultrasonography, and CT are useful in recognition of pleural effusion. In quantification of pleural effusion, the CT measurement method is superior to radiographic and ultrasonographic measurements.
Magnetic Resonance Characteristics of Ischemic Brain Infarction in Three Dogs
이기자,김영환,최성진,최수영,정인성,최호정,이영원 한국임상수의학회 2014 한국임상수의학회지 Vol.31 No.5
This case study describes the magnetic resonance characteristics of brain infarction in three dogs. Locationsof the brain infarcts were cerebella, thalamus, and multifocal. The infarcts were sharply demarcated from adjacentbrain parenchyma, homogeneous, T1-hypointense, T2-hyperintense with/without contrast enhancement, and minimalor no mass effect. Diffusion-weighted imaging (DWI) sequences were available in a dog and the infarcts werehyperintense on DWI and were hypointense on the apparent diffusion coefficient map.
개에서 컴퓨터단층촬영술을 이용한 창상성 두개강 내 출혈의 진단
이기자,최수영,오이세,최호정,이영원 로얄에이알씨 주식회사 2007 로얄동물임상의학 Vol.- No.-
두뇌창상과 두개강내 출혈은 사람과 동물에서 흔하게 발생하며 동물의 경우, 교통사고에 의한 두개강내 출혈이 가장 많고 낙상, 총상, 교상 등에 의해 발생하기도 한다. 두개강내 출혈의 부위 및 정도에 따라 임상증상과 예후는 다양하며 빠른 진단과 치료를 통해 좀 더 좋은 예후를 기대할 수 있다. 두부의 방사선 평가는 두개골의 중첩에 의해 평가하기가 어려우며 컴퓨터단층촬영(computed tomography; CT) 및 자기공명영상(Magnetic resonance imaging; MRI)을 통해 두개강내 병변의 위치 평가 및 주변 신경구조물의 변화를 확인할 수 있다. 특히 두뇌창상이 있는 경우, MRI에 비해 상용화되어 있고 촬영시간이 비교적 짧으며 두개골의 골절 평가까지 가능한 CT가 선호된다.
개에서 자기공명영상을 이용한 뇌수두증과 척수공동증 진단
이기자,최수영,오이세,최호정,이영원 로얄에이알씨 주식회사 2007 로얄동물임상의학 Vol.- No.-
Syringomyelia는 척수 내에 액체로 찬 공간이 존재하는 것을 말하며, Hydromyelia란 척수중심관의 확장을 뜻한다. 하지만 영상진단학적으로 Syringomyelia와 Hydromyelia의 구분은 어려우며 보통 이들을 통틀어 척수공동증(syringohydromyelia)이라 부른다. 척수공동증의 원인은 정확히 밝혀지지 않았으나, 선천적 척추 기형 혹은 뇌척수액의 흐름 및 흡수 장애에 의해 발생한다는 보고가 있다. 특히 카베일러 킹 찰스 스패니얼(Cavalier King Charles Spaniel)에서 후두골의 기형 및 소뇌탈출(cerebellar herniation)과 병발하여 척수공동증의 발생 빈도가 높은 것으로 보고되어 있다. 임상증상은 병변의 위치 및 병발 질병에 따라 다양하며 주로 통증 또는 사지의 신경계 증상을 유발한다.