전산유체역학을 이용한 싸이클론형 전기집진기 고도 설계 연구

이은주,장동순,나혜령,김혜숙 忠南大學校 環境問題硏究所 1995 環境硏究 Vol.13 No.-

A computer program is developed in order to figure out the physical insight of the combined dust removal equipment, that is, cyclonic electrostatic precipitator. The computer program employs Patankar's control-volume based finite-difference method, in which SIMPLEC algorithm is used for the resolution of pressure-linked momentum equation. Further two equation k-ε model is incorperated for Reynolds stresses and many empirical formulae are employed for dust charging and electric resistivity. A series of extensive parametric investigations are performed in terms of tangential velocity(swirl intensity), applied voltage across two electrodes, and particulate diameters, etc. It is found that the electrostatic force gives much more strong effect, expecially for small particulate, on the dust removal than the centrifugal force. Other calculated results are physically acceptable and consistent.

뇌실주위 백질연화증 발생 위험인자

이동환,서은숙,이우령,조명환,박재옥 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

The twenty newborn infants with periventricular leukomalacia(PVL) who were admitted to the neonatal intensive care unit of SoonChunHyang University Hospital from May 1, 1993 to July 30, 1997, were investigated for risk factors. Control group were the age matched 20 neonates who were admitted at the same time of study period. The results were as follows: 1) Mean gestational age was 31 week and mean birth weight 1665gm. 2) PVL's were located in the parietal region in 10 cases, fronto-occipital in 7 cases and parieto-occipital region in 3 cases. 3) Multiple logistic regression analysis for the risk factors of PVL showed that low birth weight, intraventricular hemorrhage, bronchopulmonary dysplasia, necrotizong enterocolitis and ventilator apply were the most significant contributing factor(P<0.05). 4) In a follow-up ultrasonograptic findings, 11 among 14 neonates with localized PVL were normalized whereas, all of 6 extensive PVL had the sequale of ventriculomegaly or cerebral atrophy. 5) In a follow-up neurologic examination, the poorer sequale including spastic diplegia or quadriplegia was associated with the larger, the more extensive PVL.

정지형 자전거 운동 훈련이 건강한 여성의 체구성,심폐기능 및 유연성에 미치는 효과

김동옥,최정숙,안혜영,민혜숙,이경숙,박연환,송미령,최명애,최정안,김매자 서울대학교 간호대학 간호과학연구소 1999 간호학 논문집 Vol.13 No.1

The purpose of this study was to determine the changes in body composition, cardiopulmonary function, and flexibility following 8 weeks' bicycle ergometer exercise training. The subjects of this research consisted of healthy adult women between 30 and 40 years of age. Initial intensity of bicycle ergometer exercise was based on the target heart rate equivalent to 55% of maximal oxygen uptake, and intensity of the exercise increased by 5% every 2 weeks. Body composition, cardiopulmonary function at rest and during maximal exercise, as well as flexibility were determined before and after 8 weeks of bicycle ergometer exercise training. Masimal exercise was performed on the treadmill according to Bruce Protocol. The results obtained were as follows; 1. There were o changes in body weight, percent body fat, fat body weight, and lean body weight as well. The ventilation volume for 1 minute, respiratory quotient and expired CO₂ volume have not changed significantly after the training, either. 2. As a result of training, resting systolic and diastolic blood pressure decreased significantly(p<.05) 3. Maximal heart rate, maximal oxygen consumption and maximal running time increased significantly after the training(p<.05) 4. Pelvic flexibility increased slightly after the training, however, it did not reach the statistical significance. Trunk flexion forward increased significantly after the training(p<.05). From these results, it may be concluded that 8 weeks bicycle ergometr training improve the cardiopulmonary function and flexibility in healthy adult women between 30-40 years of age.

Glycation 유발물질의 반응성의 비교

양용,이용갑,오두환,신동범,엄성용 한국노화학회 1993 한국노화학회지 Vol.3 No.1

머리염색이 인체에 미치는 영향

윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

Adenophora triphylla extracts reduce the fat accumulation in 3T3-L1 adipocytes and high-fat diet-induced obese mice

Dong-Ryung Lee,Young-Sil Lee,Bong-Keun Choi,Hae Jin Lee,SungBum Park,Tack Man Kim,Han Jin Oh,Joo Young Lim,Seung Hwan Yang,Joo-Won Suh 한국실험동물학회 2014 한국실험동물학회 학술발표대회 논문집 Vol.2014 No.8

Long-term clinical study and multiscale analysis of in vivo biodegradation mechanism of Mg alloy

Lee, Jee-Wook,Han, Hyung-Seop,Han, Kyeong-Jin,Park, Jimin,Jeon, Hojeong,Ok, Myoung-Ryul,Seok, Hyun-Kwang,Ahn, Jae-Pyoung,Lee, Kyung Eun,Lee, Dong-Ho,Yang, Seok-Jo,Cho, Sung-Youn,Cha, Pil-Ryung,Kwon, H National Academy of Sciences 2016 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.113 No.3

<P>There has been a tremendous amount of research in the past decade to optimize the mechanical properties and degradation behavior of the biodegradable Mg alloy for orthopedic implant. Despite the feasibility of degrading implant, the lack of fundamental understanding about biocompatibility and underlying bone formation mechanism is currently limiting the use in clinical applications. Herein, we report the result of long-term clinical study and systematic investigation of bone formation mechanism of the biodegradable Mg-5wt% Ca-1wt% Zn alloy implant through simultaneous observation of changes in element composition and crystallinity within degrading interface at hierarchical levels. Controlled degradation of Mg-5wt% Ca-1wt% Zn alloy results in the formation of biomimicking calcification matrix at the degrading interface to initiate the bone formation process. This process facilitates early bone healing and allows the complete replacement of biodegradable Mg implant by the new bone within 1 y of implantation, as demonstrated in 53 cases of successful long-term clinical study.</P>

The relevance of serum carcinoembryonic antigen as an indicator of brain metastasis detection in advanced non-small cell lung cancer.

Lee, Dong-Soo,Kim, Yeon-Sil,Jung, So-Lyoung,Lee, Kyo-Young,Kang, Jin-Hyoung,Park, Sarah,Kim, Young-Kyoon,Yoo, Ie-Ryung,Choi, Byung-Ock,Jang, Hong-Seok,Yoon, Sei-Chul Saikon Pub. Co 2012 TUMOR BIOLOGY Vol.33 No.4

<P>Although many biomarkers have emerged in non-small cell lung cancer (NSCLC), the predictive value of site-specific spread is not fully defined. We designed this study to determine if there is an association between serum biomarkers and brain metastasis in advanced NSCLC. We evaluated 227 eligible advanced NSCLC patients between May 2005 and March 2010. Patients who had been newly diagnosed with stage IV NSCLC but had not received treatment previously, and had available information on at least one of the following pretreatment serum biomarkers were enrolled: carcinoembryonic antigen (CEA), cytokeratin 19 fragments (CYFRA 21-1), cancer antigen 125 (CA 125), cancer antigen 19-9, and squamous cancer cell antigen. Whole body imaging studies and magnetic resonance imaging of the brain were reviewed, and the total number of metastatic regions was scored. Brain metastasis was detected in 66 (29.1%) patients. Although serum CEA, CYFRA 21-1, and CA 125 levels were significantly different between low total metastatic score group (score 1-3) and high total metastatic score group (score 4-7), only CEA level was significantly different between patients with brain metastasis and those without brain metastasis (p < 0.0001). The area under the receiver operating curve of serum CEA for the prediction of brain metastasis was 0.724 (p = 0.0001). The present study demonstrated that the pretreatment serum CEA level was significantly correlated with brain metastasis in advanced NSCLC. These findings suggested the possible role of CEA in the pathogenesis of brain invasion. More vigilant surveillance would be warranted in the high-risk group of patients with high serum CEA level and multiple synchronous metastasis.</P>

Clinical Correlation Between Tumor Maximal Standardized Uptake Value in Metabolic Imaging and Metastatic Tumor Characteristics in Advanced Non-small Cell Lung Cancer

Lee, Dong Soo,Kim, Seung Joon,Jang, Hong Seok,Yoo, Ie Ryung,Park, Kyung Ran,Na, Sae Jung,Lee, Kyo Young,Hong, Sook Hee,Kang, Jin Hyoung,Kim, Young Kyoon,Kim, Yeon Sil,Zhentian, Li. Williams & Wilkins Co 2015 Medicine Vol.94 No.32

<P><B>Abstract</B></P><P>This study aimed to elucidate whether the maximal standardized uptake value (SUVmax) of primary tumors in metabolic imaging correlated with pathological or metastatic characteristics and whether it was prognostic in stage IV nonsmall cell lung cancer (NSCLC).</P><P>We retrospectively reviewed the medical records of 412 eligible patients between June 2007 and January 2013. All enrolled patients fulfilled the following criteria: they were newly diagnosed with stage IV NSCLC without any previous treatment and had undergone a systemic evaluation, including 18(F)-Fluoro-2-deoxyglucose positron emission tomography/computed tomography, to assess synchronous metastatic sites. Patient and tumor characteristics were analyzed, and clinical correlations between SUVmax and metastatic features were investigated.</P><P>The median age of the study population was 65 years (range, 30–94), and 259 (62.9%) patients were male. The median SUVmax was statistically higher in males, in tumors with squamous cell histology, and in poorly differentiated tumors. Multivariate logistic regression analysis revealed that SUVmax ≥ 11.4 (top 30 percentiles) were significantly correlated with positive lymph node status (odds ratio [OR] 3.473), abdomen/pelvis metastasis (OR 1.949), and the absence of bone metastasis (OR 0.399) in the subgroup of nonsquamous NSCLC (n = 343). In Kaplan–Meier survival analysis, overall survival was significantly lower among cohorts with high SUVmax (≥11.4) than with low SUVmax (<11.4) (<I>P</I> < 0.001, median 7.4 months vs 12.1 months).</P><P>The tumors with different SUVmax have distinctive metastatic and biological features in stage IV NSCLC. The underlying mechanisms of this unique metabolic biology need to be resolved in future studies.</P>

다시기 위성영상의 융합 및 객체기반분류 기법을 이용한 농경치 추출 연구

이동국(Lee, Dong Gook),방대식(Bang, Dae Sick),양승룡(Yang, Sung Ryung),이현직(Lee, Hyun Jik) 대한토목학회 2019 대한토목학회 학술대회 Vol.2019 No.10