한국인 폐확산능 정상예측식의 임상적 유용성과 정확성

나승원 ( Seung Won Ra ),박태선 ( Tai Sun Park ),홍윤기 ( Yoon Ki Hong ),홍상범 ( Sang Bum Hong ),심태선 ( Tae Sun Shim ),임채만 ( Chae Man Lim ),이상도 ( Sang Do Lee ),고윤석 ( Youn Suck Koh ),김우성 ( Woo Sung Kim ),김동순 ( Dong 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.64 No.2

연구배경: 폐확산능을 해석하는 데 필요한 정상예측식으로는 한국인을 대상으로 하여 박 등이 개발한 식(박 식)이 있으나 아직 외국 정상예측식을 많이 사용하고 있다. 이에 국내에서 많이 사용하는 외국 정상예측식인 Burrows 식과 박 식의 임상적 유용성과 정확성을 비교하고자 하였다. 방법: 1. 임상적 유용성 연구; 2006년 7월부터 12월까지 6개월간 폐확산능검사를 시행한 환자 중 두 식을 각각 정상예측식으로 적용하였을 때 폐확산능 해석이 다른 276명(대상군 A)을 대상으로 하였다. 대상군 A에게 두 식을 각각 적용하였을 때 폐확산능 해석과 임상적 판단과의 일치도를 비교하여 임상적 유용성을 평가하였다. 2. 간질성폐질환 진단의 정확성 비교; 2001년부터 2006년까지 폐조직검사를 시행하여 확진된 간질성폐질환군과 서울아산병원에서 모집한 정상군을 대상으로 하여 정상예측식으로 두 식을 각각 적용하였을 때 폐확산능 해석의 정확도를 비교하였고, 두 식이 차이가 나는지 맥니머의 카이스퀘어 검정을 하였다. 결과: 1. 임상적 판단과의 일치도 비교; 276명을 임상정보를 토대로 폐확산능을 예측하여 분류한 결과 정상 54명, 감소 220명, 불분명이 2명이었다. 예측식으로 박 식과 Burrows 식을 적용하였을 때 임상적 판단과 일치하는 환자는 각각 78%와 22%이었다(p<0.001). 2. 간질성폐질환 진단의 정확성 비교; 박 식은 민감도 90.1%, 특이도 100%이었고 Burrows 식은 민감도 64.2%, 특이도 100%로 민감도가 통계학적으로 유의하게 박 식이 높았다(p<0.001). 결론: 우리나라 정상예측식인 박 식이 외국 정상예측식인 Burrows 식을 정상예측식으로 적용하는 것보다 임상적 유용성이나 간질성폐질환 진단의 민감도에서 더 우월하였다. 향후 폐확산능검사의 정상예측식으로 박 식을 사용해야 할 것으로 사료된다. Background: Park et al. developed the Korean reference equation for the measurement of diffusing capacity in 1985. However, the equation has not been widely used in Korea and foreign reference equations have been popularly used. We intended to compare the clinical usefulness and the accuracy of the the Korean reference equation (Park`s equation) with that of the foreign equation (Burrows` equation) that is commonly used in Korea. Methods: 1. Evaluation of clinical usefulness; Among 1,584 patients who underwent diffusing capacity (DLCO) at the Asan Medical Center from July to December 2006, group A subjects included 276 patients who had different interpretations of DLCO in trials employing Burrows` equation and Park`s equation. Clinical assessment was decided by consensus of two respiratory physicians. In order to evaluate the clinical usefulness of Burrows` equation and Park`s equation, agreement of clinical assessment and DLCO interpretation were measured. 2. Evaluation of accuracy; Group B subjects were 81 patients with interstitial lung disease (ILD) and 39 normal subjects. The 81 ILD patients were diagnosed following a surgical lung biopsy. The accuracy of diagnosing ILD as well as sensitivity and specificity were evaluated according to the use of the reference equations (Burrows` equation and Park`s equation) for DLCO. Results: Agreement between clinical assessment and interpretation of DLCO was 22% for the use of Burrows` equation and 78% for the use of Park`s equation. The sensitivity and specificity of the Burrows` equation for diagnosing ILD were 64.2% and 100%. The sensitivity and specificity of the Park`s equation for diagnosing ILD were 90.1% and 100%. The sensitivity of the Park`s equation for diagnosing ILD was significantly higher than that of Burrows` equation (p<0.001). Conclusion: The Korean reference equation (Park`s equation) was more clinically useful and had higher sensitivity for diagnosing ILD than the foreign reference equation (Burrows` equation). (Tuberc Respir Dis 2008;64:80-86)

Improvement of interlaminar properties of carbon fiber‑reinforced epoxy composites using aluminum trihydroxide

Dong‑Jun Kwon,Sung‑Min Park,Il‑Jun Kwon,Joung‑Man Park,Euigyung Jeong 한국탄소학회 2019 Carbon Letters Vol.29 No.2

This study provides an economical and effective method to improve the interlaminar properties of carbon fiber-reinforced polymers (CFRPs) using aluminum trihydroxide (ATH) microparticles. ATH microparticles are cheap and are expected to show good affinity to epoxies in the matrix and sizing agents of the carbon fibers owing to the presence of three hydroxyl groups. In addition, ATH particles are reported to improve the mechanical properties of polymers when used as the reinforcement. In this study, ATH microparticles of various sizes, 1.5, 10, and 20 μm, were used to improve the interlaminar properties of the CFRPs. ATH particles with a size of 1.5 μm improved the tensile properties of the ATH/epoxy resin and did not significantly alter the curing behavior. The interfacial adhesion between the carbon fiber and the epoxy resin was also improved, and the impregnation of the resin mixture remained similar to that of the neat resin, resulting in no significant void and defect formation. Considering the above results, the resulting 1.5 μm ATH-reinforced CFRP showed improved interlaminar properties compared to CFRP without ATH. However, 10 and 20 μm ATH-reinforced CFRPs showed deteriorated interlaminar properties due to the diminished tensile properties of the resin itself and resin impregnation, which resulted in more voids and defects, despite the interfacial adhesion between the fiber and the matrix resin.

두통을 주소증으로 하여 입원한 환자 120예에 대한 임상적 고찰

권경만 ( Kyoung Man Kwon ),김광록 ( Koang Lok Kim ),신윤리 ( Yoon Ri Shin ),박선영 ( Sun Young Park ),박동일 ( Dong Il Park ) 경락경혈학회 2012 Korean Journal of Acupuncture Vol.29 No.4

Objectives: The Purpose of this study is to investigate clinical characteristics with 120 patients who have sufferred from headache and were treated. Methods: We classified 120 patients into several groups by International Headache Society(IHS) classification and evaluated the effects of oriental medical therapy on headache. Results: 1. According to the statistics, women patients were more than men. And 50s has highest number of headache patients. 2. In classification by IHS, tension type headache were highest. 3. 24.2% of patients had entered Department of Internal Medicine, Colleage of Oriental Medicine Dongeui Univ for treatment within six month of onset. 4. According to the statistics, headache of whole part has highest number of headache patients. 5. The most number of associated symptoms were nausea, vomiting, dyspepsia etc. 6. The most number of headache patient`s past history were hypertension. 7. In classification by oriental medical differentiation of symptom and signs, the rate of blood deficiency were highest. 8. 64.2% of patients said they were satisfied with treatment, reporting half the frequency of headache or better from before treatment. Conclusions: In conclusion, the present results suggest that oriental medical therapy has effects on headache.

체지방 측정기(Futrex-1000 body fat tester)로 측정한 소아의 체지방율에 관한 연구 : 학동기와 청소년기 아동을 대상으로

박상철,이동환,신상만,이상주,박준수,최석민,안재억 순천향대학교 1992 논문집 Vol.15 No.2

Using the infrared interactance(NIR method), the percentage body fat in 1,401 Korean children, aged 6-18years, was evaluated for normal and standard values. Correlation of percentage of body fat with age, weight, height, overweight(%), Kaup index and Rohrer index was also analyzed. The following results were obtained ; 1) In all the subject, weight and height showed standard growth(50-90 percentile) compared to growth data of korean children. 2) The percentage of body fat was decreased with increasing age and was measured higher in female than male. 3) The percentage of body fat was decreased with increasing height in both sex. 4) The percentage of body fat correlated negatively with age, heght, weight in both sex. In boys, the Rohrer index appeared to have a significant positive correlation with the percentage of body fat. (r=0.52454) In girls, the overweight(%) appeared to have a significant positive correlation with percentage of body fat. (r=0.56994) The Kaup index had no correlation with the percentage of body fat. This NIR method is safe, non-invasive, rapid, easy to use, and may be useful predict percentage of body fat, especially in the mass screening.

소아 상완골 외과 골절 치료후 발생한 운반각 변화 : 운반각의 새로운 방사선적 측방 방법에 대하여 The New Radiologic Carrying Angle Measuring Method

박동만,이정윤,김경택,손성근,김성수 대한골절학회 1995 대한골절학회지 Vol.8 No.1

The lateral condyle fracture of humerus in children is the second most common fracture among the elbow fractures. In dealing with this fracture, we have frequently encountered the various complications due to physeal plate and intraarticular involvement. Change of the carrying angle is one of the common complications, but many authors reported different results about the change of carrying angle. Also, it is too difficult to measure the carrying angle during the early stage of the treatment because of cast immobilization, motion limitation of elbow, and wide variations of radiologic carrying angle according to elbow position changes. We performed this study to find the more stable and predictable new radiologic measuring mothod about the carrying angle, and then analysed the factors affecting the changes of carrying angle of the 23 patients of the lateral condyle fractures of the humerus in children who were treated and followed up more than twelve months at the Department of Orthopaedic Surgery, Dong-A University Hospital from May 1990 to April 1993. The results were as follows. 1. Carrying angles by Beals method showed variable values according to the elbow positions, but A-angles by the new measuring method were relatively stable repudless of the elbow positons. 2. Increase of clinical carrying sngle was 3 cases, decrease was 9 cases, and ranges of clinical carrying angle change were from -7 degress to +4 depees. Imease of A-angle was 7 cases, decrease was 4 cases, and ranges of A-angle change were form -10 degrees to +10 degrees. 3. The change of carrying angle showed no correlation with Jacob stage, follow up duratian, metaphyseal height and interval between injury and treatment. But the incidence and the amount of carrying angle change were increased accarding to the inaeaaed age at injury(r=0.62, P$lt;0.01). 4. Tbere were statistical significant correlation(r= -0.65, P$lt;0.01) and regreasion between the change of carrying angle and A-angle: Y -0.99X + 0.56(Y:change of clinical carrying angle, X: A- angle change), (r2=0.42, P$lt;0.01).

정신과 병실의 치료환경에 대한 평가 : (Ⅱ)3개 병실환경에 대한 특성간의 비교연구 (Ⅱ)A Comparison Study Among The Characteristics of 3 Different Therapeutic Milieus.

박정주,이만홍,신동범 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.3

The importance of milieu characteristics of psy-chiatric inpatient treatment programs has been widely recognized and a number of instruments hare been developed to measure these milieu char-acteristics. Amog these instruments, the Ward Atmosphere Scale (WAS), which was developed by Dr. Moos and his colleagues in the Social Ecology Laboratory at the Stanford University, is one of the most widely used and the most reliable test. In previous study of this series by the authers, the WAS proved to be applicable with the subs-tantial reliability in Korea and useful in system-atic comparisons among the different therapeutic milieus of Korea and possibly between the char-acteristics of American and Korean Programs. So for the next step, the authers administered the WAS to 291 subjects sampled from 3 different psychiatric inpatient wards: Custodial ward(CUW), Medically oriented ward (MOW) and the authers’ Therapeutic community ward(TCW) to assess the characteristics of social atmospheres of several different therapeutic milieus. The authers com-pared these 3 different psychiatric wards: CUW, MOW and TCW and compared the subgroups according to subject’s status in each therapeutic milieu: staff, student and patient and finally compared a Korean TCW to American Normative Sample. The results were as follows: 1. The subscale means of WAS were highest in TCW, and MOW, CUW in order. 2. According to the characteristics of Dimension of WAS, TCW was analogous to Therapeutic community program, MOW to Relationship-oriented program and CUW to Control-oriented program of Price and Moos. 3. Patients perceived their therapeutic milieus as more restricted by staffs and more difficult to express anger and aggression openly than staffs perceived in all three psychiatric wards. And staffs saw their therapeutic milieus more positively and optimistically in TCW and more negatively and pessimistically in CUW. 4. The subscale means of WAS were higher in a Korean TCW than American Normative Sample but anger and aggression was lower in a Korean TCW than American Normative Sample significantly.

경골 천정 골절에 대한 임상적 고찰

박동만,이정윤,김경택,손성근 대한골절학회 1994 대한골절학회지 Vol.7 No.2

A pilon fracture, which is defined as a comminuted intraarticular fracture of distal tibia, involve the articular surface and metaphysis with occasional extension in the diaphysis. The management has been notoriously difficult due to the associated injury, intraarticular fracture, severe communition of distal tibia, joint incongruity and soft tissue trauma. Most authors has reported good results after a surgical treatment by a priociple of AO group treatment. Rescently, Bone et all reports that ROM and outcomes of the severly comminuted or open fractures of the distal intraarticular tibia were very good in using the external fixator. The result of treatment of 22 cases were analysed at the Department of Orthopedic Surgery, Dong-A University hospital from Mar. 1990 to Feb. 1993. The results were as follows; 1. The incidence of pilon fracture is 8.3% of all anlle fracture treated during same period. 2. The most common cause of injury is fall down(63.3%). 3. The most frequent type is type 3 (54.6%).(by Rudei & Allgower) 4. The most common associated injury is compression fracture of spine and calcaneal fracture(4 cases) 5. There are eight cases open Pilon fracture(36.3%) 6. We had treated severe communited fracture and open fracture by using external fixator, we achived good ROM and outcomes. 7. The more accurate reduction, the better clinical result. 8. Complication of the Pilon fracture were traumatic arthritis, non-union, malunion, wound int, etc.

골수이식 후 발생한 출혈성 방광염 환자에서 Polyomavirus의 검출 양상

박민정,강희정,신동훈,이규만,이동건,최정현,김춘추 대한임상병리학회 2000 대한임상병리학회지 Vol.20 No.6

음향방출과 미세역학적시험법을 이용한 단일섬유강화 에폭시 복합재료의 비파괴적 섬유파단 위치표정 및 계면물성 평가

박종민,공진우,김대식,윤동진 한국비파괴검사학회 2003 한국비파괴검사학회지 Vol.23 No.5

섬유파단은 복합재료의 기계적물성을 규명하는 가장 중요한 현상 중 하나이며, 섬유파단 위치는 기지재료의 물성과 섬유표면 처리에 따라 광학현미경에 의한 방법 뿐만 아니라 음향방출법을 이용하여 확인 및 상호비교 할 수 있다. 두 개의 음향방출 센서를 단일섬유강학 에폭시 복합재료 시편 표면에 부착 시켜 연속적인 섬유파단 신호를 변형률과 측정 시간에 따라 감지하였으며, 계면전단강도는 단일섬유강화 복합재료 시험에서 광학적 방법과 음향방출법을 이용하여 측정하였다. 탄소섬유의 파단 수는 섬유표면을 전기증착으로 처리한 경우가 많았으며, 광학적인 관찰 시에 좀 더 많게 나타났다. 하지만 음향방출법과 광학적 방법에 의한 섬유파단의 위치는 작은 오차범위 내에서 상호 잘 일치하는 결과를 얻을 수 있었다. 음향방출법에 의한 섬유파단 위치표정과 파형분석은 투명, 반투명 및 불투명한 복합재료의 계면물성을 비파괴적으로 측정하기 위한 유용한 방법으로 사료된다. Fiber fracture is one of the dominant failure phenomena affecting the total mechanical performance of the composites. fiber fracture locations were measured through the conventional optical microscope and the nondestructive acoustic emission (AE) technique and then were compared together as a function of the epoxy matrix modulus and the fiber surface treatment by the electrodeposition method (ED). Interfacial shear strength (IFSS) was measured using tensile fragmentation test in combination of AE method. ED treatment of the fiber surface enlarged the number of fiber fracture locations in comparison to the untreated case. The number of fiber fracture events measured by the AE method was less than optically obtained one. However, fiber fracture locations determined by AE detection corresponded with those by optical observation with small errors. The source location of fiber breaks by AE analysis could be a nondestructive, valuable method to measure interfacial shear strength (IFSS) of matrix in non-, semi- and/or transparent polymer composites

영상분석장치를 이용한 미세흔적의 형태비교 및 특성분석에 관한 연구(Ⅲ) : 총기 발사흔 중 강선흔의 형태 비교

박성우,이정필,김동환,임세혁,김영만 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-