혈관질환 정보관리 시스템

김동익,김덕경,허세호,이병붕,김용신,김은숙,문지영,도영수,신성욱,김동수,김만태,진재욱,김용신 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.1

As medical technology progresses rapidly, there is a rise in the average age along with the Korean dietary lifestyle becoming more westernized, which leads to an increase in the number of vascular disease patients in Korea. Thus, we need to manage the medical information of a disease systematically in order to diagnose and treat constructively. However, since there has been no standardized method of man agement to date, a great deal of information could not be properly utilized nor studied. Therefore, the departments of Cardiology, Radiology and Neurology of Samsung Seoul Hospital recently got together to develop an information management system called the Vascular Data System. This program was developed to be run on win98 O/S, upper Pentium Ⅲ, and upper 128 MB Memory, and its source code is Dephi 4.0. It was configured for the user to set the configurations as well as do a variety of search and analysis. If this program were to be updated continuously, it may be used extensively as well as in various parts of clinical research activities.

임상 가검물에서 분리된 균(대장균과 황색 포도균)의 약제 내성

김중명,김재식,김경선,김재룡,전동석,최성만,서상철,김인자,김재숭,이건일,김경숙 慶北大學校 醫科大學 1982 慶北醫大誌 Vol.23 No.2

1981년 1월에서 12월말까지 임상 제료에서 분리한 Escherichia coli (E. coli)와 Staphylococcus aureus (S. aureus) 중에서 무작위로 각 50주 씩 선택하여 원판 확산법과 평판 희섭법으로 그 내성주를 조사하여 다음과 같은 성적을 얻었다. 전체적으로 볼 때에 Teteracyclin (TET), Chloramphenicol (CM) 및 Ampicillin (AMP)에 대한 내성주가 가장 많았고, Amikacin (AMK)에 대한 내성주는 가장 적어다. 이것을 균종별로 보면 E. coli에 있어서는 TET, AMP 및 CM는 원판 확산법으로서 74∼76%, 평판 희석법으로서는 78∼94%가 내성주임을 나타내었고, 또 Cephalothin(CEP)은 원판 확산법에서는 8%가 내성주로 나타났으나, 평판 의석법에서는 52%가 내성주로 나타났다. S. aureus에 있어서는 TET는 원판 확산법으로 82%, 평판 희석법으로서는 78%가 내성주로 나왔고 Penicillin (P)은 원판 확산법에서는 56% 평판 희석법으로는 22%의 내성주가 나왔으며, GM과 CM은 원판확산법에서는 18∼44%, 평판 희석법에서는 56∼58%가 내성주로 나왔다. Each 50 strains of Escherichia coli and Staphylococcus aureus were selected at random out of the stock cultures which were isolated from the clinical materials in the bacteriological laboratory of the department of clinical pathology. Kyungpook National University Hospital from the first of January to the end of December in 1982, and their resistance against eight antibiotics were as follows; Escherichia coli and Staphylococcus aureus had the most resistant pattern against tetracyclin, chloramphenicol, and ampicillin, while they had the most sensitive pattern against amikacin in general. Escherichia coli revealed resistant pattern to tetracyclin, ampicillin, and chloramphenicol 74-76% by the disk diffusion method and 78-94% by the plate dilution method, and revealed resistant pattern to cephalothin 8% by the disk diffusion and 52% by the plate dilution. Staphylococcs aureus disclosed resistant pattern to tetracyclin 82% by the disk diffusion and 78% by the plate dilution, and disclosed resistant pattern to penicillin 56% by the disk diffusion and 22% by the plate dilution, and to gentamicin and-chloramphenicol 18-44% by the disk diffusion and 56-58% by the plate dilution.

관상동맥질환을 동반한 모야모야병 1례

김동기,이영태,김기향,김성만,김대경,김두일,김동수 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Moyamoya disease is an occlusive intracranial arteriopathy with an abnormal cerebral vascular collateral networks. Although this disease is known to be associated with stenosis of extracranial arteries, such as the renal artery, a case associated with stenosis of the coronary artery is extremely rare. We report a case of coronary artery occlusive disease affected by Moyamoya disease. The patient was a 38-year-old female experiencing intermittent headache and exer tional chest pain. Cerebral MRI showed complete obstruction of both internal carotid arteries and abnormal cerebrovascular systems which confirmed Moyamoya disease. Coronary angiography showed a significant stenosis of left anterior descending coronary artery ostium with TIMI grade I collateral blood flow from the normal right coronary artery. After coronary artery stenting and medical treatment for headache, her subjective symptoms were relieved. In Moyamoya patient, an evaluation of the extracranial (especially coronary artery) vascular system should be considered if there are some evidences of coronary artery disease.

家兎及人體寄生肝吸蟲 各種抗原에 依한 皮膚反應과 沈降反應의 比較實驗

崔東翊,申大植,金正浣,金正萬 慶北大學校 醫科大學 1963 慶北醫大誌 Vol.4 No.1

The alkali & acid soluble protein fractions and Polysaccharide fractions from the adult Clonorchis sinensis of rabbit and man were employing the identical method, and further study was carried out in the skin and precipitin reaction in order to determine the best antigen among the fraction. The results observed are summarized as follow: Ⅰ.Skin reaction 1)There is no significant difference in positive rate and reactivity between man and experimental rabbit's alkali soluble protein fraction and acid soluble protein fraction. 2)In the polysaccharide fraction, the positive rate of antigen fractionated from man's Clonorchis sinensis is higher than antigen from rabbit. 3)The positive rate of antigen fractionated from man's Clonorchis sinensis is 47.5%(38 cases among 80), whereas from antigen of rabbit, it is 6.1%(5 cases among 82) in the polysaccharide fraction remained acid media. Ⅱ.Precipitin reaction 1)No apparent differences are observed in the titres of precipitin reactons fractionated from the alkali soluble protein & polysaccharide fraction, and also from the acid soluble protein and polysaccharide fraction of man and rabbit Clonorchis sinensis. 2)The titre of precipitin reaction is higher in the polysaccharide fraction in the case of serum of human patient, while it is higher in the protein fraction in the cases of rabbit serum.

지적장애인의 건강체력과 비만도의 관계

김동만 ( Dong Man Kim ) 한국특수체육학회 2014 한국특수체육학회지 Vol.22 No.3

본 연구목적은 지적장애인의 비만도(BMI, 체지방량, WHR)와 건강체력 요소를 비교 분석 후, 각각의 건강체력 요소와 비만도의 상관관계를 파악하는 데 있다. 연구 대상은 특수학교와 장애인보호시설의 지적장애인 906명으로 하였다. 이 연구는 측정된 지적장애인의 건강체력 요소(심폐지구력, 근력, 근지구력, 유연성)와 비만도(BMI, WHR, 체지방률)의 관계를 분석하기 위해 경로분석을 실시하였으며, 연구결과는 다음과 같다. BMI 비만도는 남성 지적장애인의 근력, 근지구력, 유연성 그리고 여성 지적장애인의 근력, 근지구력에 유의하게 영향을 미치는 것으로 나타났다. WHR 비만도는 남성 및 여성 지적장애인의 근지구력에 유의하게 영향을 미치는 것으로 나타났다. 체지방률 비만도는 남성 지적장애인의 근지구력, 심폐지구력 그리고 여성 지적장애인의 근력에 유의하게 영향을 미치는 것으로 나타났다. 지적장애인의 비만도 측정에 가장 적합한 방법은 체지방률로 나타났다. 남성지적장애인은 근력, 근지구력, 유연성, 심폐지구력이 비만도와 관계가 있으며, 여성지적장애인은 근력, 근지구력이 비만도와 관계가 있는 것으로 나타났다. 지적장애인의 규칙적인 운동 및 신체활동은 건강체력을 향상시켜 장기적으로 비만도 해결에 중요한 역할을 할 것이다. 따라서 지적장애인의 효율적인 비만 관리를 위해서는 기본적으로 근력, 심폐지구력, 유연성 등의 건강체력을 향상시킨 후 운동 및 신체활동량을 증가시켜야 한다. 본 연구는 지적장애인의 비만을 질병으로 규정하여 사전 예방과 사후 관리를 체계적으로 실시할 수 있도록 신뢰도 높은 후속 연구가 필요하므로 건강체력을 측정 및 적용한 개인별 누적 기초 자료를 연령별, 장애등급 등으로 세분화시켜야 할 것이다. The purpose of this study is to analyze the relationship between health-related physical fitness and obesity rate, after examining and comparing the factors of obesity rate (BMI, body fat, & WHR) and health-related physical fitness in people with intellectual disabilities. Subjects are 906 people with disabilities who are in special school and day care institution. To archive this, path analysis was applied to analyze the relationship between health-related physical fitness (cardiorespiratory, muscle strength, muscle endurance, & flexibility) and obesity rate (BMI, body fat, & WHR) and the results are as followed. BMI obesity rate has significant effects on the strength, muscular endurance of both men and women with intellectual disabilities. WHR obesity rate has also significant effects on the muscular endurance of men and women with intellectual disabilities. Body fat obesity rate has significant effects on the muscular endurance and cardiac endurance of men with intellectual disabilities and the strength of women with intellectual disabilities. It is shown that body fat rate is the most appropriate index to measure the obesity rate of people with intellectual disabilities. In men`s case, obesity rate is related to strength, muscular endurance, flexibility and cardiac endurance. In women, obesity rate is related to strength and muscular endurance. Obesity exercise program for intellectual disabilities should start from strength reinforcement and increasingly expand their physical activity to cardiac endurance and flexibility. The regular exercise and physical activity in people with intellectual disabilities improves health and will be an important role to solve obesity rate in the long term. Therefore, basically, after improving health-related physical fitness, such as muscle strength, cardiorespiratory, & flexibility, etc, exercise and physical activity will be improved to manage obesity rate effectively in people with intellectual disabilities. There is a need for follow-up study which has high reliability, based on systematic prevention and post management. Therefore the accumulated basic data with records of physical fitness condition for each individual should be subdivided according to age and the degree of disability.

家兎及人體寄生肝吸蟲 各種抗源에 依한 皮膚反應과 沈降反應의 比較實驗

崔東翊,申大植,金正浣,金正萬 慶北大學校 醫科大學 1963 慶北醫大雜誌 Vol.4 No.1

췌장을 침습한 위의 암육종 1 예

김병호,김효종,조진만,김윤화,이정일,동석호,장영운,황일섭,장 린 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.1

Carcinosarcoma of the stomach is regarded as a rare malignant neoplasm composed of both carcinomatous and sarcomatous components in a given tumor. Few cases have been reported since 1904. This is a case of carcinosarcoma of the stomach in a 61-year-old man. He suffered from indigestion, vomiting, and epigastric pain. Endoscopic finding showed a huge protruding mass with intact mucosa on the posterior wall of the antrum up to the pylorus. Surgery was performed and carcinosarcoma with pancreatic invasion was confirmed by pathology.

흰쥐 해마박편에서 veratrine과 고농도 포타슘자극시 칼슘이온이 gamma-aminobutyric acid 유리에 미치는 영향에 관한 연구 : A role of calcium

강수만,김형룡,김관식,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.2

Present study was performed to clarify the effect of calcium on the release of gamma-aminobutyric acid (GABA) employing hippocampal slices. Hippocampal slices(300-400㎛ thick) were prepared by the method of Kim et al(1988) and pre-equilibrated in Krebs-bicarbonate medium(KBM, pH 7.4) for 1hr at 37℃. In case of veratrine-induced GABA release, pre-equilibrated slices were incubated in fresh KBM and then veratrine (25μM)-containing KBM for 10min period in the presence or absence of 2.5mM Ca^2+. In case of potassium-induced GABA relaese, pre-equilibrated slices were incubated in fresh KBM and then potassium(50mM)-containing KBM for 5min period in the presence or absence of 2.5mM Ca^2+. Basal and veratrine and potassium-induced release of GABA was determined from recovered medium by HPLC. The observed results were as follows: 1. The release of GABA induced by the 10min-exposure of 25μM veratrine and 5min-exposure of 50mM potassium in the presence of 2.5mM Ca^2+ was 228.9±11.2 nmol and 100.1±8.9nmol, respectively. When compared with released amounts of GABA during the corresponding spontaneous periods, these were 6.8 and 4.6-fold increase respectively. 2. The release of GABA induced by the 10min-exposure of 25μM veratrine and 5min-exposure of 50mM potassium in the absence of Ca^2+ was 381.4±30.2 nmol and 55.1±4.1 nmol, respectively. When compared with released amounts of GABA during the corresponding spontaneous periods, these were 11.3 and 2.4-fold increase respectively.

췌장의 가성낭종 파열에 의한 하부 위장관 출혈 1예

장성종,김병수,부귀범,김동규,박찬국,김만우,김정용,박상헌 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Pancreatic pseudocysts usually develop as a complication of acute pancreatitis or repeated attacks of chronic pancreatitis. Pseudocysts may also develop as a result of traumatic injuries or neoplasms. An uncommon complication is massive hemorrhage inside the pancreatic pseudocyst. The exact mechanism of hemorrhage is unknown. Enzymatic digestion, pressure erosion from the cyst mass or a combination of these processes may play an important role. Gastrointestinal hemorrhage associated with a pancreatic pseudocyst can occur in 10 percent of cases. When hemorrhage occurs because of erosion into a blood vessel involved in the pseudocyst, surgery is indicated since the episodes of hemorrhage are often severe and may even be fatal. When there is colonic involvement, various complications may occur. The most dangerous one is spontaneous rupture into the colon, which requires immediate surgical treatment because of high incidence of fulminating sepsis or massive hemorrhage. We examined a sixty eight-year-old man complaining of hematochezia and dizziness, and reported that it was a case of massive lower gastrointestinal hemorrhage caused by pseudocyst of the pancreas ruptured into the colon associated with chronic pancreatitis. On operative findings, the peripancreatic fatty tissue had severe adhesions to transverse colon and tail portion of pancreas, where the pseudocyst had formed. A distal pancreatectomy, splenectomy and resection of transverse colon were performed. By microscopic examination, hemorrhagic necrosis and inflammatory change were observed in the pancreas specimen. The tail portion of pancreas had a 6×6 cm sized cystic mass and was proven to be a pseudocyst with no epithelial lining.

判別分析法을 利用한 脂肪肝의 高危險群 豫測

朴鏞萬,金埈淵,金東一,李常柱,朴耕一,金源述,鄭甲烈 동아대학교 부설 산업의학연구소 1995 산업의학연구소 논총 Vol.- No.2

This study was carried out on 484 persons who visited Dong-A University Hospital Human Dock Center from March to August 1992. The objective of this study is prediction of high risk group of fatty liver from obesity, liver function test, and serum lipid levels using method of discriminant analysis, in general screening of health check, especially abdominal ultrasonography was not done. Result of discriminant analysis were 328 cases in control group, 267 were predicted correctly to be members of control group(81.4%), while 61 were assinged incorrectly to fatty liver group. Similarly, 95 out of 70(73.7%) of the fatty liver group were identified correctly, and 25(26.3%) were misclassified. The overall percentage of cases classified correctly was 79.67%.