간호전공과 비 간호전공 여대생의 모유수유 지식과 태도, 실천 지속 의지에 대한 연구

김수정,김희진,동민영,박소민,송예슬,이고은,이승만,장지은,정유진,최예슬 이화여자대학교 간호과학대학 2013 이화간호학회지 Vol.- No.47

Purpose: This study was conducted as benchmark to improve breast-feeding educational programs by comparing knowledge, attitude, and practical volition between female nursing college students and non-nursing college students. Method: The survey was conducted on 236 female students from ‘E’ and ‘Y’ Universities which were located in Seoul. The sample consisted of 114 nursing and 122 non-nursing college students. The data were collected using self-administered questionnaires from October 25 to December 17, 2012. The collected data were analyze dusing SPSS20.0. Result: The nursing college students’ level of knowledge, attitude and practical volition toward breast feeding was higher than non-nursing college students. There was positive correlation between knowledge and practical volition and attitude and practical volition about breast-feeding in nursing college students. But non-nursing college students had positive correlation between knowledge and attitude, and knowledge and practical volition about breast-feeding. Conclusion: Based on the results of the research, there was a correlation between knowledge, attitude, and practical volition toward breast feeding. It was suggested that technical knowledge of breast feeding be offered to female college students, as well as nursing college students. It could help them have the right information on breast feeding. It was also suggested that educational programs to reinforce emotional⋅practical attitude based on the knowledge of breast feeding be developed. Also, this study suggested that female students get their practical education in breast feeding under any circumstances with the practical volition to breast feed. Improving the knowledge, attitude, and the practical volition toward breast feeding, will increase the rate of breast feeding.

구기자 및 구기엽 추출물의 피부과색소 조절효과

김동희 ( Dong Hee Kim ),이수연 ( Soo Yeon Lee ),김남경 ( Nam Kyung Kim ),윤보경 ( Bo Kyung Youn ),정다솜 ( Da Som Jung ),최은영 ( Eun Young Choi ),홍소리 ( So Ri Hong ),윤지영 ( Ji Young Yoon ),강명화 ( Myung Hwa Kang ),이진영 ( J 한국응용생명화학회(구 한국농화학회) 2011 Journal of Applied Biological Chemistry (J. Appl. Vol.54 No.4

구기자, 건조구기엽, 생구기엽 추출물의 미백효과를 검증하였다. Tyrosinase 저해활성 측정결과 건조구기엽 에탄올추출물 500 μg/mL에서 44%의 저해활성을 나타내었으며, melanoma cell (B16F10)에서의 melanin 생합성 저해율 측정결과 건조구기엽 에탄올 추출물 50 μg/mL에서 14%의 저해효과를 나타내었다. 구기자, 건조구기엽, 생구기엽 추출물을 처리한 B16F10군 에서는 tyrosinase protein의 발현이 처리하지 않은 군보다 감소 하였다. 특히, 건조구기엽 추출물의 경우 tyrosinase의 단백질 발현량을 많이 저해하였다. 결과적으로 건조구기엽 추출물의 미백활성이 가장 우수하였으며, 식품 및 화장품의 기능성 소재로 이용이 가능할 것으로 판단된다. The objective of the present study was to evaluate the skin whitening effect of the extracts, Lycii fructus (LF), Dry-L. foilum (DLF) and Fresh-L. folium (FLF). Tyrosinase inhibition activities was 44% in DLF ethanol extracts at a 500 μg/mL. When the tyrosinase activities in B16F10 murine melanoma cell were tested, the activities in DLF ethanol extracts was 14% at a 50 μg/mL concentration. The protein expression of microphthalmia-associated transcription factor, tyrosinase related protein 1 (TRP-1), TRP-2, and tyrosinase, which are all melanin related factors, showed that LF, DLF and FLF extracts inhibited the protein bio-synthesis in B16F10 melanoma cell. Especially the DLF extract showed greater decrease of protein expressions. Results indicate that the DLF extract tested in the present study had skin whitening activity and can be used as a function a ingredients for food and cosmetic compositions.

유리系 內의 Ferrite의 Mossbauer Spectra

安振盛,金俊植,李敬行,趙壽烈,董徹,洪致裕 동국대학교 자연과학연구소 1984 자연과학연구 논문집 Vol.4 No.-

本 硏究는 5NiO-5CdO-10Fe₂O₃-30Na₂CO₃-10SiO₂(mole %)유리계에 대한 Mossbauer parameter의 溫度依存性을 조사하였다. Mossbauer spectrum은 한쌍의 Quadrupole doublet의 중첩으로 fitting하였으며 이중 하나는 tetrahedral site,다른 하나는 octahedral site이다. 상대적인 共鳴吸收面積比로부터 octahedral site와 tetrahedral site에 대한 Debye temperature를 계산하여 본 결과 각각 418K, 449K 임을 알았다. 또한 θ?값들을 이용해 least square method로 isomer shiftdral site의 壓力依存系數 α와 2.97×10?mm/sec K, I.S(0)일때의 를 평가해본 결과 octahedral site의 α는 2.97×10?mm/sec K,I.S(0)는 tetrahedral site이고 α의 3.2305×10?mm/sec K, I.S(0)는 0.276mm/sec임을 알았다. 그리고 quadrupole splitting은 측정온도가 증가함에 따라 서서히 감소함을 알았다. The temperature dependence of the Mossbauer parameter for 5NiO-5CdO-10Fe₂O₃-30Na₂CO₃-10SiO₂(mole %) quenched glass system was investigated. The spectra were fitted as superposition of a pair of quadrupole double ; One is for the tetrahedral site and the other is for the octahedral site. From the relative absorption area ratios of the spectra, the Debye erature of two sites were calculated to be 418K and 449K for the octahedral site and the ?edrai site, respectively. From these Debye temperatures, We can see that the isomer shifts and the coefficients αof the pressure dependence of the isomer shift are 0.456mm/sec, 2.97×10?mm/sec K for octahedral site and 0.276mm/sec K, 3.2305×10?mm/sec K for ?edral site. Also, we can see that the quadrupole splittings of two sites are gradually decresed the increase of the measuring temperature.

Deletions of 9p21 and TP53 in Bladder Cancer

Park, W.-S Korean Academy of Medical Science 1996 Journal of Korean medical science Vol.11 No.3

ECAP으로 제조된 초미세립 저탄소강의 단열성 전단밴드의 미세조직 변화

황병철,이성학,김용찬,김낙준,신동혁 대한금속재료학회 2005 대한금속·재료학회지 Vol.43 No.5

The object of the present study is to investigate the microstructural development of the adiabatic shear band formed by dynamic torsional experiments of ultra-fine-grained low-carbon steels fabricated by equal channel angular pressing (ECAP). Dynamic torsional tests were conducted on four steel specimens, two of which were annealed after ECAP, using a torsional Kolsky bar, and then the test data were compared via microstructures, tensile properties, and fracture mode. The ECAP'ed specimen consisted of very fine, equiaxed grains of 0.2 !Am in size, which were slightly coarsened and had an equiaxed shape after annealing. Some adiabatic shear bands were observed at the gage center of the dynamically deformed torsional specimen, and their width was smaller in the ECAP'ed specimen than in the 1-hr annealed specimen, although they were not found in the 24-hr annealed specimen. Ultra-fine, equiaxed grains of 0.05~0.2 μm in size were formed inside the adiabatic shear band, and their boundaries had characteristics of high-angle grain boundaries. These phenomena were explained by dynamic recovery and recrystallization due to the highly localized plastic deformation and temperature rise occurred within the shear band. The temperature rise in the shear band formation process was inferred to be above 540℃ from the observation of spheroidization behavior of cementites in pearlite grains. (Received February 7, 2005)

박판주조법으로 제조된 Zr계 벌크 비정질 합금의 미세파괴기구

이정구,이동근,이성학,김낙준,조경목,박익민 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.2

The mechanical property improvement of a strip-cast Zr-base bulk amorphous alloy was explained by clarifying fracture mechanisms. Effects of crystalline phase particles formed in the amorphous matrix during strip casting on strength, ductility, and fracture toughness were explored in detail by directly observing microfracture processes using an in situ loading stage installed inside a scanning electron microscope (SEM) chamber. The compressive and fracture toughness test results indicated that ductility, strength, and fracture toughness of the atrip-cast amorphous alloy were higher than those of the as-cast monolithic amorphous alloy, although the strip-cast alloy contained a considerable amount (4.5 vol. %) of hard, brittle crystalline particles. This improvement of mechanical properties in the strip-cast alloy could be plausibly explained by mechanisms of (1) blocking of crack propagation, (2) formation of multiple shear bands, and (3) crack deflection by crystalline particles. Such property improvement presents new applicability of the strip-cast amorphous alloy containing crystalline particles to structures and components requiring excellent fracture toughness.

TiN, TiCN, CrN 박막의 고온 산화

백창현,홍주화,위명용,김기영,이동복 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.8

The oxidation behavior of TiN, TiCN and CrN coatings sputtered on a steel substrate was investigated at 850℃ in air. Both TiN and TiCN oxidized to Tio₂ while CrN oxidzed to Cr₂O₃. The oxidation resistance decreased in the order of CrN, TiN and TiCN. During oxidation, the outward diffusion of substrate elements such as Fe, Si occurred to a certain degree. The enrichment of substrate element of Cr at the oxide scale and the depletion of nitrogen at the lower part of the unoxidized CrN coating were observed.

막힘온도 지시계를 이용한 액체 나트륨중 불순물 농도 측정

권상운,정경채,김병호,김광락,황성태,최윤동,정지영 한국공업화학회 1998 응용화학 Vol.2 No.2

The monitoring of impurity in sodium is one of the most important R&D issues to develop a liquid metal reactor. Impurity measuring experiments were carried out by a Plugging Temperature Indicator, which is an on-line impurity monitoring instrument. Plugging temperature was successfully measured at various oxygen contents with two operation modes- bare orifice mode and partially plugging mode. The relation between plugging temperature and oxygen content was calibrated from the experimental data. Further study is needed to develop a more reliable instrument.

Linear Accelerator를 이용한 Stereotactic Radiosurgery

정상섭,윤도흠,오성훈,김선호,서창옥,추성실,노준규,김동익,서정호 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.6

A Modified irradiation technique utilizing a linear accelerator for radiation surgery within the brain was performed in 4 patients. Three of them had brain tumors and one small arteriovenous malformation in midbrain. A Hitchcock stereotactic apparatus and a 10 MeV linear accelerator have been adapted and special computer programs for dosimetry were obtained and studied experimentally with a phantom model. Stereotactic radiosurgery is a valuable tool in the treatment of inoperable, deep seated intracranial lesions, the major advantage being high efficacy and smoothness of the procedure, as well as short hospitalization times.

Long‐term efficacy and safety of bosutinib in patients with advanced leukemia following resistance/intolerance to imatinib and other tyrosine kinase inhibitors

Gambacorti‐,Passerini, Carlo,Kantarjian, Hagop M.,Kim, Dong‐,Wook,Khoury, Hanna J.,Turkina, Anna G.,Brü,mmendorf, Tim H.,Matczak, Ewa,Bardy‐,Bouxin, Nathalie,Shapiro, Mark,Turnbu John Wiley and Sons Inc. 2015 American journal of hematology Vol.90 No.9

<P>Long‐term efficacy and safety of bosutinib (≥4 years follow‐up from last enrolled patient) were evaluated in an ongoing phase 1/2 study in the advanced leukemia cohort with prior treatment failure (accelerated‐phase [AP, <I>n =</I> 79] chronic myeloid leukemia [CML], blast‐phase [BP, <I>n =</I> 64] CML, acute lymphoblastic leukemia [ALL, <I>n =</I> 24]). Fourteen AP, 2 BP, and 1 ALL patient remained on bosutinib at 4 years (vs. 38, 8, 1 at 1 year); median (range) treatment durations: 10.2 (0.1–88.6), 2.8 (0.03–55.9), 0.97 (0.3–89.2) months. Among AP and BP patients, 57% and 28% newly attained or maintained baseline overall hematologic response (OHR); 40% and 37% attained/maintained major cytogenetic response (MCyR) by 4 years (most by 12 months). In responders at 1 versus 4 years, Kaplan‐Meier (KM) probabilities of maintaining OHR were 78% versus 49% (AP) and 28% versus 19% (BP); KM probabilities of maintaining MCyR were 65% versus 49% (AP) and 21% versus 21% (BP). Most common AEs (AP, BP) were gastrointestinal (96%; 83%), primarily diarrhea (85%; 64%), which was typically low grade (maximum grade 1/2: 81%; 59%) and transient; no patient discontinued due to diarrhea. Serious AEs occurred in 44 (56%) AP and 37 (58%) BP patients, most commonly pneumonia (<I>n =</I> 9) for AP and pyrexia (<I>n =</I> 6) for BP; 11 and 13 died within 30 days of last dose (2 considered bosutinib‐related [AP] per investigator). Responses were durable in ∼50% AP responders at 4 years (∼25% BP patients responded at year 1, suggesting possible bridge‐to‐transplant role in BP patients); toxicity was manageable.Am. J. Hematol. 90:755–768, 2015. © 2015 The Authors. American Journal of Hematology Published by Wiley Periodicals, Inc.</P>