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      • KCI등재

        Service Quality Gap Model for Analysis and Improvement of Plastic Surgery Customer Satisfaction in South Korea

        Dandan Yu,Lanmeng Wu,LIUZIYANG 한국무역통상학회 2020 무역통상학회지 Vol.20 No.5

        The purpose of this study is to examine the experiences of customers who go to Korea to undergo plastic surgery. This study applies the quality-of-service gap model to understand and analyze customer satisfaction and service demand and to know various measures and suggestions to improve medical services. A questionnaire survey is adopted according to the basic theory of the service quality gap model. Based on actual conditions of hospital work in Korea, the gap model of medical service quality is established. SPSS22.0 statistical package was used to analyze and process data. Results show that plastic surgery customers’ perception of medical services is higher than expected. At the same time, plastic surgery customers indicate the highest evaluation of the quality of medical services. These customers have the highest expectation of assurance in medical service quality and the lowest expectation on empathy. Among the plastic surgery clients in various age groups, the younger ones exhibit greater difference between the expected value and actual perceived value in terms of the reliability of medical service quality. Therefore, we can conclude that the service quality gap model is feasible in analyzing and improving the satisfaction of hospital patients. This model is a reliable theoretical reference that hospital administrators can use to address issues related to medical service quality.

      • KCI등재

        Solvothermal Synthesis of TiO2/CNFs Heterostructures with Photocatalytic Activity

        Dandan Yu,Jie Bai,Yulong Gu,Chunping Li 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.6

        Titanium dioxide nanoparticles (TiO2 NPs) embedded carbon nanofibers (CNFs) have been successfully prepared by electrospinning technique, solvothermal synthesis and high-temperature calcination processes. The as-obtained products were characterized by field-emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), UV-Vis diffuse reflectance spectra (DRS) and Fourier transform infrared (FTIR) spectra. The results of characterization revealed that solvothermal treatment and high-temperature calcination were beneficial to the synthesis of anatase TiO2. Compared to the as-fabricated TiO2 powder, TiO2 NPs contained in the TiO2/CNFs were successfully grown on the surface of CNFs without aggregation. The photocatalytic activities of the TiO2/CNFs heterostructures were evaluated by the degradation of methyl orange (MO) under UV light irradiation for 14 h. The TiO2/CNFs exhibited higher photocatalytic activities than pure TiO2 powder, which were attributed to the small size of TiO2 NPs, electron transfer, high adsorption properties of CNFs and the formation of heterostructures between TiO2 and CNFs. Moreover, in aqueous solution, the as-prepared TiO2/CNFs could be easily recycled for the application of CNFs.

      • KCI등재

        CBX7 Rejuvenates Late Passage Dental Pulp Stem Cells by Maintaining Stemness and Pro-angiogenic Ability

        Wu Yu,Li Bing,Yu Dandan,Zhou Zhixuan,Shen Ming,Jiang Fei 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.3

        BACKGROUND: Ever-growing tissue regeneration causes pressing need for large population of stem cells. However, extensive cell expansion eventually leads to impaired regenerative potentials. In this study, chromobox protein homolog 7 (CBX7) was overexpressed to rejuvenate late passage dental pulp stem cells (DPSCs-P9). METHODS: The recruitment of copper ions (Cu2?)-activated hypoxia-inducible factor-1a (HIF-1a) to the CBX7 gene promoter was confirmed by chromatin immunoprecipitation assay. Functions subsequent to Cu2?-induced or recombinant overexpression of CBX7 on proliferation, multipotency, odontoblastic differentiation and angiogenesis were investigated in vitro, while murine subcutaneous transplantation model was used to further detect the effects of Cu2?-induced CBX7 overexpression in vivo. RESULTS: Our data displayed that CBX7 overexpression maintain proliferation and multipotency of DPSCs-P9 almost as strong as those of DPSCs-P3. Both gene level of odontoblast-lineage markers and calcium precipitation were nearly the same between CBX7 overexpressed DPSCs-P9 and normal DPSCs-P3. Moreover, we also found upregulated expression of vascular endothelial growth factor in DPSCs-P9 with CBX7 overexpression, which increased the number of capillary-like structures and migrating co-cultured human umbilical vein endothelial cells as well. These findings indicate CBX7 as an effective factor to rejuvenate late passage stem cells insusceptible to cell expansion. Cu2? has been proved to achieve CBX7 overexpression in DPSCs through the initiation of HIF-1a-CBX7 cascade. Under Cu2? stimulation since P3, DPSCs-P9 exhibited ameliorated regenerative potential both in vitro and in vivo. CONCLUSION: Long-term stimulation of Cu2? to overexpress CBX7 could be a new strategy to manufacture large population of self-renewing stem cells.

      • KCI등재후보

        Composite hydrogels filled with inclusion complexes made from β-cyclodextrins with poly(propylene glycol) bisamine

        Huaiqing Yu,Hongliang Wei,Dandan Hou,Ai-ying Zhang,Zeng-guo Feng 한국물리학회 2007 Current Applied Physics Vol.7 No.s1

        A novel kind of composite hydrogel lled with inclusion complexes (ICs) made fromb-cyclodextrins (b-CDs) with amine-terminatedpoly(propylene glycol) (PPG-BA) was prepared by copolymerization of methacryloyl end-capped poly(L-lactide)-poly(ethylene glycol)-poly-(L-lactide) macromer (DMPEGL) with acrylic acid (AA) in water under UV irradiation. Owing to the hydrogen bonding interactionof COOH in AA on the network backbones with NH2 and OH in ICs embedded in the crosslinked network, the composite hydrogelsmechanical properties being signicantly improved. The mass loss test conducted in water indicates that they degrade by following a dualdegradation mechanism, that is, not onlyb-CDs slipping from the polymer axles and then escaping out of the hydrogel network, but alsothe bulk hydrogel network hydrolyzing itself to lose the weight. These composite hydrogels show potential to be used as biomaterials fortissue engineering scaolds and carriers of drugs with controlled release.

      • KCI등재

        Genetic localization of the SPC gene controlling pod coiling direction in Medicago truncatula

        Xiaocheng Yu,Qiulin Qin,Xia Wu,Dandan Li,Shengming Yang 한국유전학회 2020 Genes & Genomics Vol.42 No.7

        Background Handedness in plants introduced by helical growth of organs is frequently observed, and it has fascinated plant scientists for decades. However, the genetic control of natural handedness has not been revealed. In the model legume Medicago truncatula, pods can be coiled in a clockwise or anti-clockwise manner, providing a model for genetic analysis of plant handedness. Objective We aimed to localize the Sense of Pod Coiling (SPC) gene controlling pod coiling direction in M. truncatula. Methods Linkage analysis was used with a biparental population for fine mapping of the SPC gene. The genome sequence of M. truncatula Mt4.0 was used for marker identification and physical mapping. Single nucleotide polymorphisms (SNPs) between the parental lines were converted to CAPS (cleaved amplified polymorphic sequences) markers. Genetic map was constructed using the software JoinMap version 3.0. Gene predication and annotation provided by the M. truncatula genome database (http://www.medic agoge nome.org) was confirmed with the programs of FGENESH and Pfam 32.0, respectively. Quantitative reverse transcription PCR (qRT-PCR) was used to analyze the relative expression levels of candidate genes. Results The genetic analysis indicated that the anti-clockwise coiling is dominant to clockwise and is controlled by the single gene, SPC. The SPC gene was delimited to a 250 kb-region on Chromosome 7. Total of 15 protein-coding genes were identified in the SPC locus through gene annotation and sequence analysis. Of those, two genes, potentially encoding a receptor-like kinase and a vacuolar cation/proton exchanger respectively, were selected as candidates for the SPC gene. Conclusions The result presented here lay a foundation for gene cloning of SPC, which will help us to understand the molecular mechanisms underlying helical growth in plant organs.

      • KCI등재

        Association between Delayed Lactogenesis II and Early Milk Volume among Mothers of Preterm Infants

        Xiurong Yu,Jianhua Li,Xiangyun Lin,Dandan Luan 한국간호과학회 2019 Asian Nursing Research Vol.13 No.2

        Purpose: This study aimed to evaluate the effect of delayed lactogenesis Ⅱ on early milk volume in mothers expressing milk for their preterm infants. Methods: 142 mothers with preterm infants participated in a longitudinal cohort study, the milk volumes over 14 days postpartum between mothers with delayed lactogenesis Ⅱ ( 72 hours) and mothers with non-delayed lactogenesis Ⅱ(< 72 hours) were compared using Wilcoxon's rank sum tests. Results: The prevalence of delayed lactogenesisⅡ among mothers of preterm infants was 36.0% (36/100). There existed negative correlations between the onset of lactogenesis Ⅱ and the daily milk volumes( rs ¼ 0.525~0.354, p ¼ .002 ~ p < .001). The milk volumes in every 24-hour of the 14 days postpartum in delayed group were significantly less than that in non-delayed group (p ¼ .002 ~ p < .001). After controlling for the covariates, pregnancy-induced hypertension syndrome, delayed expression initiation, shorter daily sleeping time were found to be the risk factors for delayed lactogenesis Ⅱ. Conclusion: Delayed lactogenesis Ⅱ was associated with lower milk volume in early postpartum period. Women who were at risk for delayed lactogenesis Ⅱ need targeted interventions and additional support during pregnancy and postpartum.

      • KCI등재

        MiR-494-3p Upregulation Exacerbates Cerebral Ischemia Injury by Targeting Bhlhe40

        Lingjiang Sun,Dandan Ji,Feng Zhi,Yu Fang,Zigang Zhu,Tong Ni,Qin Zhu,Jie Bao 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.4

        Purpose: Cerebral ischemia is related to insufficient blood supply and is characterized by abnormal reactive oxygen species(ROS) production and cell apoptosis. Previous studies have revealed a key role for basic helix-loop-helix family member e40 (Bhlhe40)in oxidative stress and cell apoptosis. This study aimed to investigate the roles of miR-494-3p in cerebral ischemia/reperfusion(I/R) injury. Materials and Methods: A mouse middle cerebral artery occlusion (MCAO/R) model was established to mimic cerebral ischemiain vivo. Brain infarct area was assessed using triphenyl tetrazolium chloride staining. Oxygen-glucose deprivation/reoxygenation(OGD/R) operation was adopted to mimic neuronal injury in vitro. Cell apoptosis was analyzed by flow cytometry. Therelationship between miR-494-3p and Bhlhe40 was validated by luciferase reporter and RNA immunoprecipitation assays. Results: Bhlhe40 expression was downregulated both in MCAO/R animal models and OGD/R-induced SH-SY5Y cells. Bhlhe40overexpression inhibited cell apoptosis and reduced ROS production in SH-SY5Y cells after OGD/R treatment. MiR-494-3p wasverified to bind to Bhlhe40 and negatively regulate Bhlhe40 expression. Additionally, cell apoptosis and ROS production in OGD/R-treated SH-SY5Y cells were accelerated by miR-494-3p overexpression. Rescue experiments suggested that Bhlhe40 could reversethe effects of miR-494-3p overexpression on ROS production and cell apoptosis. Conclusion: MiR-494-3p exacerbates brain injury and neuronal injury by regulating Bhlhe40 after I/R.

      • Feeling In Control : Design Tangible Self-Health Management Service Touch-Points For The Elderly With Holistic Experience

        Zhiyong Fu,Dandan Yu,Shuangshuang Zhang 한국HCI학회 2013 한국HCI학회 학술대회 Vol.2013 No.1

        This paper presents how to improve the holistic user experience for the elderly with chronic disease by designing the new self-health management service based on multi-screen platform and tangible touch points. As the connected touch point, Med-Cube is designed to help the elderly feel in control when they handle with the complicated multi-screen devices, like TV, tablet PC and mobile phone. In order to create seamless connection between the elderly and the multi-screen service system, we designed the context aware interaction flow based on the elderly’s common experience and behavior of everyday self-health management, such as recording, reminding and navigating. This selfhealth service system helps the elderly to create integrated user experience between virtual online world and physical world as well. The self-health service system also links the elderly with family, friends and doctors by cross-media platform and social network. Our vision in this study is to give the elderly independent, healthy, self-controlled life by providing service from the tangible touch points and holistic cross-media interaction mode.

      • KCI등재

        The Influence of Service Quality of E-Commerce on Consumer Satisfaction Degree and Repurchase Intention : The Case of Leisure Food E-Commerce in China

        Lanmeng Wu,Dandan Yu,Ziyang Liu 한국무역통상학회 2020 무역통상학회지 Vol.20 No.6

        In recent years, the proportion of leisure food in E-commerce platforms has kept increasing year by year for its attribute characteristics and the rapid development of E-commerce platforms, but some problems have also emerged. This paper aims at studying the influence of service quality on customer satisfaction and repurchase intention by means of specific division of service quality of E-commerce with leisure food E-commerce being an example. In this paper, the collected data is analyzed in terms of reliability and validity, factor analysis and construction of equation models in the form of questionnaires with software SPSS and AMOS. The conclusions obtained from analysis include: 1. Customers’ expectation before purchasing has a significant positive impact on consumer satisfaction. 2. The assumption that E-commerce web design has a significant positive impact on consumer satisfaction is false. 3. E-commerce logistics has a significant positive impact on consumer satisfaction. 4. The quality of e-commerce products has a significant positive impact on consumers. 5. E-commerce after-sales service has a significant positive impact on consumer satisfaction. 6. Consumer satisfaction has a significant positive impact on repurchase intention.

      • KCI등재

        Research on soil net nitrogen mineralization in Stipa grandis grassland with different stages of degradation

        Wanyu Wen,Xiaobing Li,Lihong Chen,Dandan Wei,Han Wang,Meng Zhang,Jing Yu 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.4

        Net nitrogen mineralization is one of the nitrogen cycling process, and it is very important to understand nitrogen mineralization characteristics in degradation grassland. In the upper 0–10 cm soil layer of Stipa grandis P. A. Smirn. grassland in the Xilin river basin, Inner Mongolia, we studied the soil net nitrogen mineralization and nitrification among three varying stages of degradation grassland and analyzed the relationship between the mineralization rate of the soil net nitrogen and environmental factors, using the resin-core incubation method. Our results demonstrated that, from May to October 2012, the accumulated net nitrogen mineralization was 21.620 mg kg–1, 12.486 mg kg–1, and 48.053 mg kg–1 in the slightly, medium, and heavily degraded grasslands, respectively and varied greatly among the three stages of degradation shown by the S. grandis grassland plots. During the cultivation period, the variation of net nitrogen mineralization and nitrification was similar to the variation of soil mineral nitrogen. The higher soil mineral nitrogen content indicated higher mineralization of net nitrogen. In July and August, soil moisture was positively correlated with the net nitrogen mineralization rate, and the correlation coefficients between these two factors of 0.73, 0.58, and 0.79 for the slightly, medium, and heavily degraded plots, respectively. The rates of net nitrogen mineralization and nitrification were negatively correlated with soil total nitrogen, but positively correlated with C/N ratio, and weakly correlated with other physicochemical properties.

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