상염색체우성 다낭신의 임상경과 및 합병증

이상주,이영모,이한규,최대은,박기현,이강욱,신영태 충남대학교 의학연구소 2001 충남의대잡지 Vol.28 No.2

Autosomal dominant polycystic kidney disease(ADPKD) is one of most common hereditary disorder. It is potentially fatal and the major mobilities are hypertension and renal failure. To elucidate clinical characteristics and outcomes of ADPKD, 67 ADPKD patients were analyzed retrospectively. The male to female ratio was 48 years for males and 42 years for females. The factors leading to the dignosis of ADPKD were flank or abdominal pain (46%), palpable abdominal mass (24%), incidental findings (18%), gross hematuria and headache. Urinalysis result showed hematuria (31%), proteinuria (19%), pyuria (18%). Among renal complications hypertension (67%) was the most common. Other complications were urolithiasis (16%) upper urinary tract infection (9%), cyst infection (7%). Azotemia was observed in 24% of cases. Echocardiography showed left ventricular hypertrophy in 24% and valvular regurgitation in 18% of cases, but there was no mital valve prolapse. Cerebrovascular events occurred in 6 cases (2 cases of intervertebral hemorrhage and 4 cases of cerebral infarction). Hipatic cyst were observed in 64% of cases. Eighteen cases culminated in end stage renal failure (ESRF) at an of 47. According to this study, the most common complications of ADPKD was hypertension (67%), ESRF (27%), and cerebrovascular event (9%). Hypertension was more frequently observed in increased creatinine group than normal.

염료제거능 곰팡이균주의 동정 및 염료 제거 특성에 관한 연구

이제혁,황규대,전억한 경희대학교 환경연구소 1995 環境硏究 論文集 Vol.6 No.-

F-2 isolates cultured on the agar plate containing the dyestuff has formed the clear zone around the strain. The morphology of F-2 was observed with microscope and identified as Penicillium janthinellum(subgenes Furcatum var. Divaricatum). The effects of pH on the absorbace of dyestuff almost not shown except above pH 12 and so the decrease of dye concentration during the incubation of Penjanthinellum is caused by the ability of Penjanthinellum that can remove the dyestuff. The pH and dry cell weight in the incubation of Penjanthinellum have changed after 18 hours and the decrease of the dye concentration in the medium has occured simultaneously. The rates of dye removal were good under the conditions of almost pH ranges except above pH 10 and 0.01g/100㎖ of dye was almost removed in over 3.0g/ℓ of starch concentration. In the case of l%(v/v) inoculum of Penjanthinellum in the 100㎖medium, 0.01g/100㎖ of dyestuff was almost removed in the 20 hours.

염료 분해능 곰팡이의 분리 및 분해능 조사

이제혁,황규대,전억한 경희대학교 환경연구소 1994 環境硏究 論文集 Vol.5 No.-

Dyes released into the environment from textile waste water are considered to be a serious polution problem because of the wide spread into environment with a variety of colorants. 12 strains of the dye-degradable fungi were isolated from the soil. Among 12 stains, F-2 showed the highest degradability if dye, was selected for the further dye-degradation study. As a result of the submerged culture of fungi, F-2, in the media containing dye stuff, the specific peak(542㎚) of dye in media was diminishd as cultibation time goes by. The optimum pH and temperature of F-2 were 7-8 and 30℃, respectively. More than 80% of dye in the reactor was removed within 48hts and the agatation speed in the reactor was shown to be optimal at this experoment. It is considered that after waste treatment of the textile waste water by F-2, drained water will not effect th pH of an aquatic condition.

Pen.janthinullum에 의한 염료의 흡착 제거 특성

이제혁,황규대,전억한 慶熙大學校 1996 論文集 Vol.25 No.-

Dyes released from dyestuff industry and textile industry causes various pollutional problems and poisonous to the organisms. The dye-adsorbable fungus has been isolated and identified as Pen.janthinellum. The optimal temperature and initial pH in the growth of Pen.janthinellum was 30℃ and 7, respectively. It is showed that dye (0.01g/100㎖) is removed completely in the culture broth. When starch as the carbon source is used, the removal of dye was 89% and so starch is available as carbon source for dye removal. And 3g/ℓ above of starch concentration is necessary for remonal of dye(0.01g/100㎖). Apollo Nylon Fast Red S2B., Nylon Fast Red M-E7B., Apollocion Red H-E7B., Apollocion Red H-E3B. was removed about 90.2, 89.3, 87.6, 85.6%, respectively. In the case of detergent addition, the impovement of adsorbability was not shown. It is identified that dead cells have the adsorbability of dye and assumed applications in the waste water treatment.

곰팡이균의 액내배양법에 의한 염료 분해

이제혁,황규대,전억한 慶熙大學校 1994 論文集 Vol.23 No.-

Dyes released into the environment from the textile industries are considered to be serious to cause polution problem. 12 strains of the dye-degradable fungi were isolated from the soil and strain showing high activity for biodegradation of dyes used for investigation was selected from 12 strains and coded as F-2. F-2 strain was grown in the medium containing dye as a submerged culture at pH 7∼8 and 30℃ and a dye investigated was degraded at high level(80%) within 48hrs. Comparatively mild agitation speed of impeller(150rpm) was used for the cultivation of fungi F-2.

생약추출물 섭취와 운동이 비만 Zucker 쥐의 혈청 IGF-1/IGFBP-3 수준에 미치는 영향

이헌규,조인호,양대승 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

The purpose of this study was the investigation of the effect of embro and regular exercise on blood glucose. insulin and IGF-1 and IGFBP-3(Insulin Like Growth Factor Binding Protein) level against obese zucker ratfa/fa. In general. IGF-Ⅰ play important role in the regulation somatic growth. metabolism. cellular proliferation/differentiation. With insulin, IGF-Ⅰ is another regulation factor for blood glucose concentration. For this study, obese zucker rats(n=21) were divided into three group: the control(no exercise, CON, n=7), embro group(no exercise but supplement embro, emb개, n=7). and embro+exercise(n=7). Animals in exercise group were run on treadmill for 12week (5day/week^(-1), 1h^(-1)/day^(-1), 20m/min^(-1) speed). After 12 week, All animals (CON and EX) were anesthetized by sodium pentobarbital and blood was extracted and frozen for further analysis. Plasma glucose and insulin concentration were significantly decreased in embro and embro+ exercise than CON(P<.05). and Blood IGF and IGFBP-3 level were significantly increased in embro and embro+ exercise group(P<.05). Thus. These results suggest that embro and regular exercise may has protective effect in insulin resistance by controlling blood glucose and increasing IGF-1/ IGFBP-3 in obese zucker rat.

D.C Magnetron sputtering법으로 제조된 GMR 스핀밸브 조성막에서 증착변수들이 증착속도에 미치는 영향

조대현,이찬규,김병수 國立 昌原大學校 産業技術硏究所 1998 産技硏論文集 Vol.12 No.-

In this study, we have investigated the influence of sputtering conditions(Ar pressure, Input power) on deposition rate of Ni81Fe19, Fe, Co, Cu, Cr86A114, Cr93Ga7 thin films produced by the method of DC magnetron sputtering. In all films, we have observed that the deposition rate increased with input power because of increasing sputter yield, and ion current density. we have found that the deposition rate was decreased with the pressure of Ar gas.

원발성 두개골내 수막종 : 1예 보고 A Case Report

김대호,홍현숙,조준희,박재성,박성진,차장규,백상현,이혜경 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Primary intraosseous meningioma of skull is rare, and often confused with a primary bone tumor. We report a case of a 71 years old female patient with an intraosseous calvarial meningioma of frontal bone presenting as a solitary osteolytic skull lesion. Plain skull radiograph, CT and MR images show sharply marginated expansile bony lesion in frontal skull vault, and a small well enhanced soft tissue mass within bone. The mass is extracranially protruded to scalp, and is partially attached to the underlying dura. Outer and inner table of skull vault is slightly bulged out, suggesting intradiploic origin of the tumor. The tumor was treated with surgical excision and cranioplasty. Histological examination revealed fibrous meningioma.

중등 컴퓨터과학교육을 위한 객체지향형 EPL '두리틀'의 적용 및 평가

권대용,길혜민,염용철,유승욱,進兼宗,靖久野,이원규 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.6

제 7차 컴퓨터교과 교육과정은 소프트웨어 활용 부분에 치중되어 컴퓨터과학에 관한 원리교육이 이루어지지 못하고 있다. 한편, ACM K-12 컴퓨터과학 교육과정 모델에 관한 보고서에서는 현재의 컴퓨터교육이 그릇된 방향이며 컴퓨터과학 중심의 컴퓨터교육을 위해서 프로그래밍언어 교육을 통한 원리교육의 중요성을 강조하고 있다. 본 논문에서는 프로그래밍 체험학습을 위한 객체지향 기반의 새로운 교육용프로그래밍언어인 두리틀(Dolittle)을 소개한다. 두리틀은 간결한 구문과 한국어와의 대응성, 인크리멘탈 방식의 프로그래밍, 수치, 문자열, 배열과 같은 알고리즘과 구조화, 텍스트 위주의 프로그래밍 등의 설계방침을 적용한 언어이다. 중학생을 대상으로 실제 수업에 적용해 보고 학습효과를 분석한 결과, 객체지향기반이지만 클래스나 상속 등의 개념을 모르고도 활용 가능한 교육용프로그래밍언어라는 것을 확인할 수 있었다. 또한 객체와 메소드 활용을 통하여 프로그래밍 결과를 쉽게 확인할 수 있고 오류 수정이 용이하므로, 학생들의 높은 흥미도를 유지하면서 학업성취도를 향상시키고 차후 학습으로의 연계가 수월하였다. Current computer education is difficult to educate basic concepts and principals of the computer science because the 7th curriculum of computer education is focused on the application of software. According to the ACM K-12 report about the computer science education model, current computer education is taking the wrong way and we should put the highly priority on the education of the fundamentals through programming languages for a better computer education oriented to the computer science. This paper introduces a new object-oriented educational programming language "Dolittle'". The design principals of Dolittle are simple syntax of Korean, incremental programming, text based programming, aliasing of function, and object-oriented programming. Being applied to middle school classes, we can confirm that Dolittle is easy to learn, and gives rise to high interest and keeps interest through a course,and also is of great practical use in class for programming novice.

문학교육과 수용미학

김용성,이대규 全北大學校 敎育大學院 1996 敎育論叢 Vol.16 No.-

This thesis point to the theoretical construction of student-centered literary education methodology and scholastic systematization of literary education. Till now most literary education was usually cramming education only by instructers. We thought that literary education must be student-centered. Learner-centered education of the literature can overcome the demerits of the current cramming education and aim at the harmony between cognitive and affective domain in education. In this paper, the reception theory is applied to the text of 「A river」 (Seo. Jeong-In). We are suggest that the method for understanding and appreciation of the literary text filling the indeterminacy with the reader's imagination, wether it was intended by the writer or not.