Three Poems by Yun Dong-ju

Yun Dong-ju,Lee In-soo(번역자) The Academy of Korean Studies 1965 Korea Journal Vol.5 No.9

Combination treatment for onychomycosis using 1,064-Nd:YAG laser and efinaconazole 10% topical Solution

( Sang Ju Lee ),( Dong Woo Suh ),( Won Soon Chung ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Onychomycosis is one of the most common nail disease around the world. No specific treatment other than drug therapy and surgery has been suggested till present. Systemic treatment with antifungal drugs for onychomysosis is effective. However, a long treatment time is required and it is not suitable for people with other systemic disease. Furthermore, it may cause many side effects such as liver diseases. For that reasons, topical drugs or physical treatments are preferred by many patients. Recently laser treatment for onychomycosis has been proposed. The efficacy of treatment is less than systemic drugs but, laser is more convenient, safe and accessible in treatment. As a result, the combination therapy using 1064 Nd:YAG laser and efinaconazole 10% topical solution was performed. Two patients with onychomycosis were treated with 1064 Nd:YAG laser (PinPointe FootLaser, Cynosure, Westford, MA, USA) once a month with application of 10% eifnaconazole solution(Jublia, Dong-A EST) once a day. All three patients were treated successfully. We considered a combination treatment of a 1064 Nd:YAG laser and efinaconazole 10% topical solutions would be an effective, safe, and convenient treatment method for onychomycosis.

Combination treatment for onychomycosis using 1,064 Nd:YAG laser and efinaconazole 10% topical solution

( Sang Ju Lee ),( Dong Woo Suh ),( Won Soon Chung ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: Onychomycosis is one of the most common nail disease around the world. No specific treatment other than drug therapy and surgery was suggested till present. Systemic antifungal drugs for onychomysosis are effective. However, they require a long treatment time and not suitable for people with other systemic disease. Furthermore, they may cause many side effects such as liver disease. Also, many patients prefer topical drugs or physical treatment. Objectives: The objective of this study was to evaluate the efficacy of combination treatment with a 1064 Nd:YAG laser and efinaconazole 10% Topical Solution. Methods: Ten patients with onychomycosis were treated with 1064 Nd:YAG laser (PinPointe FootLaser, Cynosure, Westford, MA, USA) once a month with application of 10% eifnaconazole solution(Jublia, Dong-A EST) once a day. The effectiveness of treatment were evaluated with before and after photographs. Results: Improvement were shown in 90% of patients after the treatment. However, 10% of patients had no response. Conclusion: This clinical study suggests that combination treatment of a 1064 Nd:YAG laser and efinaconazole 10% Topical Solutionis an effective, safe, and convenient treatment method for onychomycosis.

Alkylhalide가 Mouse의 LDH isozyme 분포에 미치는 영향 : Cellulose Acetate Electrophoresis Method

권미경,김영옥,박은주,이동화,이명미,이문희,이양자 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

The effect of Carbontetrachloride administration on Lactatedehydrogenase isozyme patterns were analyzed by cellulose acetate electrophoresis for the brain, heart, kidney, lung, liver and mouse muscle. Each other tissue was found to have a characteristic distribution of these isozymes. At normal condition, aerobic tissue such as brain, heart, kidney, and lung were found to have all five isozymes from LDH_1 to LDH_5, while anaerobic tissues such as liver and muscle were found to have superiorly LDH_5 The toxicity of Carbontetrachloride administration was most prominence in the liver, and lung toxicity was occured also.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

28세 여성에서 Epinephrine 국소 주사 후 발생한 스트레스성 심근병증 1예

임주견,곽성동,박재영,천재홍,최성열,차태준,이준상 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

Stress induced cardiomyopathy is characterized by transient left ventricular dysfunction with typical regional wall motion abnormality of basal segment hyperkinesia and apical hypokinesia after physical or psychological stress. Stress induced cardiomyopathy mimics acute myocardial infarction but coronary angiography shows normal and usually recovers rapidly. Stress induced cardiomyopathy appears to occur almost exclusively in old females. Only a few cases have been reported in younger women but not yet in korea. The pathogenesis is not well known. Currently, it is thought that catecholamine may play important role. Especially, epinephrine may be most important catecholamine in the pathogenesis of steress induced cardiomyopathy. We report a case of stress induced cardiomyopathy occurred in young female after local epinephrine injection for hemostasis during tonsillectomy. 스트레스성 심근병증은 고령의 여성에서 주로 발생하며 카테콜라민 중 특히 epinephrine이 병리기전의 주요한 원인의 하나로 생각되어지고 있다. 저자들은 28세의 젊은 여성에서 편도절제술 도중 지혈을 목적으로 epinephrine을 국소 주사한 후 발생한 스트레스성 심근병증 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.

杜詩章法硏究

李永朱 한국중국어문학회 2000 中國文學 Vol.33 No.-

杜詩盡發古今之體勢, 而無所不備, 尤其是章法, 卓然獨高, 古今無比, 當謂詩家之模辯. 自筆者所窺而說之, 其章法略有三指向. 其一, 要融合相反相背之二律. 其二, 要探究所以貫通諸體之章法. 其三, 要試作變格,拙讀, 緣於地面限制, 不得不止於其一之一部分而已. 其餘期於下回續論. 此回所論, 大槪始 一, 杜誇融合相反之二律, 以造咸其所擅長之嚴密結構, 當展開誇想時, 置重於轉變, 又資脈絡應接, 因此文勢自有似斷不斷, 相應相避之妙, 恰如行雲流水, 或流暘, 或頓挫, 變化無窮, 而不露斧遊. 二, 杜誇, 無古律無長短, 每篇布置整密, 每段分界謹嚴, 行文自有起伏. 各段句數, 必訓於漏意, 多寡勻稱, 詳略相應. -篇之內, 必有開頭本論末謠之結構, 開頭破題以領下, 末尾承上暇或就題結, 彧開一步, 本論所言, 井幷有條, 意興迭出, 以示章法之妙諦.

β-naphthol 유도체 합성 및 항종양활성 검토

이주영,류수진,박예진,황순호,이마세,김인종,김동현,김신규 慶熙大學校 1996 論文集 Vol.25 No.-

Sythesis of β-naphthol derivatives and their anti-tumor activity were investigated. Binaphthol 1 obtained from β-naphthol by oxidative C-C bond formation(phenoloxydation) was converted into its derivatives. Treatment of 1 with POCl_3 followed by aziridine introduction gave phosphoryl aziridine 3. Also, diaziridine 5 was obtained from 1 by chlorination and successive aziridine introdution. Typical chemical transformation of 1 to obtain ester-type afforded compound 7 and 8. Compound 5 was the most effective derivative of the tested compounds on their anti-tumor activity.

回轉굽힘을 받는 高周波硬化鋼의 疲勞壽命分布에 관한 尤度區間推定

周東仁,李致雨 慶南大學校 附設 工業技術硏究所 1992 硏究論文集 Vol.10 No.-

機械構造用炭素鋼SM45C를 高周波硬化熱處理하여 여러가지 作用應力아래에서 回轉굽힘疲勞實驗을 實施하여 疲勞壽命分布를 尤度區間推定法에 의하여 推定하면 從來의 區間推定法은 尤度區間推定法과 比較하면 有意側으로 推定될 可能性이 있으며 最尤推定法은 尤度區間推定法의 特別한 경우로서 尤度區間推定法중에 包含 될 수가 있는 것으로 思料된다. 또한 區間推定法은 주로 少數 샘플데이타의 評價에 必要하지만 尤度區間推定法도 少數샘플데이타의 評價에도 그 효(?)果를 기대할 수가 있다. The purpose of this study is due to test of rotating bending fatigue under the various stress of machanical structural carbon steel(SM 45C)hardened induction heat treatment. To estimation results of likelihood interval estimation for fatigue life distribution, interval estimation in the past is able to be estimated side of significance to compare likelihood interval estimation method, maximum likelihood estimation method is considered to include likelihood interval estimation method. Also, Interval estimation method largly needs to evaluate small sample fatigue data, however, likelihood interval estimation method can be expected its effect of evaluation of small sample fatigue data.

주사 탐침 현미경을 이용하여 표면 처리한 기판 위의 DNA 관찰

이남주,손정민,진상협,전동렬,강치중 명지대학교 자연과학연구소 2004 자연과학논문집 Vol.23 No.-

대장균에서 추출한 plasmid DNA를 운모 기판에 착상시켜 주사 탐침 현미경으로 관찰하였다. plasmid DNA를 운모 기판에 착상시키기 위하여 운모 기판을 염 이온으로 0.01~10mM까지 농도를 변화시켜 표면 처리하였다. 운모 기판 위 염 이온의 농도 차이를 X-선 광전 분광기(XPS)로 표면을 분석하였다. 기판 처리에 사용한 염 이온의 농도에 영향을 받아 착상된 DNA의 밀도 및 모양이 변화하였다. 운모 기판 처리 농도에 따른 AFM 영상 차이와 XPS로 분석한 기판 위의 염 이온의 상태를 제시하고, 이들 사이의 상관관계에 대하여 논의하였다. The plasmid DNA on mica is observed using scanning probe microscopy. The mica surface is treated by 0.01~10mM NiCl_(2) for depositing the plasmid DNA. Concentration difference of NiCl_(2) on mica is analyzed a treated mica surface using XPS. The plasmid DNA on the treated mica has a difference of density and conformation in proportion as Ni^(2+) concentration. We present AFM topology difference and Ni^(2+) states on mica by XPS, discuss interaction between AFM topology difference and Ni^(2+) states on mica