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      • KCI등재

        Applying technological organization environmental model to examine the adopting intention of e-freight for the air freight forwarder

        Ching-Cheng Chao,Fang-Yuan Chen,Ching-Chiao Yang,Chien-Yu Chen 인하대학교 정석물류통상연구원 2016 JOURNAL OF INTERNATIONAL LOGISTICS AND TRADE Vol.14 No.1

        The e-freight program launched by the International Air Transport Association (IATA) has gradually become a standard specification for international air freight operations. This study examined critical factors affecting air freight forwarders’ decision to adopt the IATA e-freight using a technology-organization-environment model with air freight forwarders in Taiwan as the base. Our findings show that ‘information technology (IT) competence’, ‘trading partner pressure’, ‘government policy’ and ‘competitive pressure’ all have significant positive effects on air freight forwarders’ decision to adopt the e-freight and the top three factors among these are ‘government funding’, ‘government’s active promotion’ and ‘government’s requirement of electronic air waybill (e-AWB)’. Finally, this study proposes strategies that can encourage air freight forwarders to decide on e-freight adoption for the information of relevant oK regyawniozradtison International Air Transport Association (IATA); IATA e-freight; Technology organization environment model; Air freight forwarder

      • Joining of the Sinter Hardening Pully by Sinter Brazing

        Cheng Chao-Hsu,Lin Yi-Ching,Lin Yan-Cherng,Hwang Lih-Ren 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

        This research mainly focuses on the development of sinter brazing technology for improving the process related to belt pulley made by sinter hardening. As the machine process of belt pulley takes up more than half of the total manufacturing hours, we propose changing the process to pulley groove brazed and bonded with pulley disc by applying sinter brazing to belt pulley. With the new process, the belt pulley is expected to reduce manufacturing cost to 70% of the original process by applying the sinter brazing technology; and the belt pulley bound by sinter brazing only loses 10% bonding strength compared with the original process.

      • KCI등재

        Magnetic field effects on the electric modulus properties of nematic mixture E7

        Lei-Ching Huang,Chao-Ming Fu,An-Cheng Sun,Chia-Wei Lee 한국물리학회 2014 Current Applied Physics Vol.14 No.1

        The molecular dynamics of the homogeneously aligned nematic liquid crystal mixture E7 subject to a magnetic field has been studied. The dielectric spectra study has revealed a low bias magnetic field effect on the evolution of dielectric relaxation spectra occurred at lower (wkHz) (d-relaxation) and higher (wMHz) (a-relaxation) frequency regions. The complex electric modulus, which converted from experimental dielectric spectra, has been analyzed with theoretical model of Debye relaxation. The obtained fitting parameters of relaxation time and strength of dielectric components are shown to vary systematically with the strength of applied magnetic field. A microscopic molecular dynamic model has been proposed to describe the two-step variation of E7 molecular under the bias magnetic field. The results provide implication for magneto-modulation of liquid crystal molecular dynamics under the bias magnetic field.

      • KCI등재

        A study on sustainable management of Taiwanese cultural design and creative industries - Based on events of Dajia Mazu Pilgrimage-

        Sheng-Ching Yang,Kuen-Ho Chiang,Chao-Jen Cheng,Kim, Young Sam 한국일러스트레이션학회 2015 일러스트레이션 포럼 Vol.16 No.42

        Cultural creative design industries play animportant role in breaking through thepredicament when products are short ofdistinctive features. A thorough study oncultural creative industries has not been donein terms of sustainable development due toprevious focus on environment policy. Throughparticipation in the survey and in-depthinterviews with the temple and businesses;first we learned that the tourists joined thepilgrimage tended to rubberneck and pray andmost of the tourists purchased the localproducts of Dajia. Second, in regard ofinnovation of traditional culture, there is nosufficient integration of tourism, transportationand accommodation facilities which makes itdifficult for the tourists to stay for a longerperiod. Third, in terms of cultural creativity,the businesses agreed on the positive benefitcultural creative products have brought to thelocal economy although some products havenot been changed to keep the traditionalculture.

      • KCI등재

        Sulforaphane Decrease of SERTAD1 Expression Triggers G1/S Arrest in Breast Cancer Cells

        An-Chin Cheng,Ching-Ju Shen,Chao-Ming Hung,Yi-Chiang Hsu 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.5

        Studies have identified the potential of chemopreventive effects of sulforaphane (SFN); however, the underlying mechanisms of its effect on breast cancer require further elucidation. This study investigated the anticancer effects of SFN that specifically induces G1/S arrest in breast ductal carcinoma (ZR-75-1) cells. The proliferation of the cancer cells after treatment with SFN was detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. DNA content and cell cycle status were analyzed through flow cytometry. Our results demonstrated the inhibition of growth in ZR-75-1 cells upon SFN exposure. In addition, SERTAD1 (SEI-1) caused the accumulation of SFN-treated G1/S-phase cells. The downregulation of SEI-1, cyclin D2, and histone deacetylase 3 suggested that in addition to the identified effects of SFN against breast cancer prevention, it may also exert antitumor activities in established breast cancer cells. In conclusion, SFN can inhibit growth of and induce cell cycle arrest in cancer cells, suggesting its potential role as an anticancer agent.

      • KCI등재

        Suture Repair in Endoscopic Surgery for Craniovertebral Junction

        Mei-Yin Yeh,Wen-Cheng Huang,Jau-Ching Wu,Chao-Hung Kuo,Hsuan-Kan Chang,Tsung-Hsi Tu,Peng-Yuan Chang,Yu-Shu Yen,Henrich Cheng 대한척추신경외과학회 2019 Neurospine Vol.16 No.2

        Objective: Endoscopic approaches to the craniovertebral junction (CVJ) have been established as viable and effective surgical treatments in the past decade. One of the major complications is leakage of the cerebrospinal fluid (CSF). This study aimed to investigate the efficacy and feasibility of suture closure at the nasopharyngeal mucosa upon durotomy. Methods: A series of consecutive patients who underwent different endoscopic approaches to the CVJ were retrospectively reviewed. The pathologies, surgical corridors, neurological and functional outcomes, radiological evaluations, and complications were analyzed. Different strategies of repair for the intraoperative CSF leakage were described and compared. Results: A total of 22 patients covering 13 years were analyzed. There were 12, 2, and 8 patients who underwent transnasal, transoral, and combined approaches, respectively. There were 8 patients (36.4%) who experienced intraoperative CSF leakage, and were grouped into 2: 4 in the nonsuture (NS) group and 4 in the suture-repaired (SR) group. The NS group had 3 (75%) persistent CSF leakages postoperation that caused 1 mortality, whereas patients of the SR group had only 1 minor CSF rhinorrhea that healed spontaneously within days. Conclusion: In this series of 22 patients who required anterior endoscopic resection of pathologies at the CVJ, there was 1 (4.5%) serious complication related to CSF leakage. For patients who had no durotomy, the mucosal incision at the nasopharynx usually healed rapidly and there were few procedure-related complications. For patients with intraoperative CSF leakage, suture closure was technically challenging but could significantly lower the risks of postoperative complications.

      • KCI등재

        Measurement of Deformity at the Craniovertebral Junction: Correlation of Triangular Area and Myelopathy

        Chih-Chang Chang,Jau-Ching Wu,Chin-Chu Ko,Hsuan-Kan Chang,Yi-Hsuan Kuo,Chao-Hung Kuo,Tsung-Hsi Tu,Wen-Cheng Huang 대한척추신경외과학회 2022 Neurospine Vol.19 No.4

        Objective: Diseases of the craniovertebral junction (CVJ) are commonly associated with deformity, malalignment, and subsequent myelopathy. The misaligned CVJ might cause compression of neuronal tissues and subsequently clinical symptoms. The triangular area (TA), measured by magnetic resonance imaging/images (MRI/s), is a novel measurement for quantification of the severity of compression to the brain stem. This study aimed to assess the normal and pathological values of TA by a comparison of patients with CVJ disease to age- and sex-matched controls. Moreover, postoperative TAs were correlated with outcomes. Methods: Consecutive patients who underwent surgery for CVJ disease were included for comparison to an age- and sex-matched cohort of normal CVJ persons as controls. The demographics, perioperative information, and pre- and postoperative 2-year cervical MRIs were collected for analysis. Cervical TAs were measured and compared. Results: A total of 201 patients, all of whom had pre- or postoperative MRI, were analyzed. The TA of the CVJ deformity group was larger than the healthy control group (1.62 ± 0.57 cm2 vs. 1.01 ± 0.18 cm2 , p < 0.001). Moreover, patients who had combined anterior odontoidectomy and posterior laminectomy with fixation had the greatest reduction in the TA (1.18 ± 0.58 cm2 ). Conclusion: In CVJ deformity, the measurement of the cervical TA could indicate the severity of brain stem compression. After surgery, the TA had a varying degree of improvement, which could represent the efficacy of surgery.

      • KCI등재

        Impact of the COVID-19 vaccine booster strategy on vaccine protection: a pilot study of a military hospital in Taiwan

        Wang Yu-Li,Cheng Shu-Tsai,Shen Ching-Fen,Huang Shu-Wei,Cheng Chao-Min 대한백신학회 2023 Clinical and Experimental Vaccine Research Vol.12 No.4

        Purpose: The global fight against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has led to widespread vaccination efforts, yet the optimal dosing schedule for SARS-CoV-2 vaccines remains a subject of ongoing research. This study aims to investigate the effectiveness of administering two booster doses as the third and fourth doses at different intervals to enhance vaccine protection. Materials and Methods: This study was conducted at a military regional hospital operated by the Ministry of National Defense in Taiwan. A cohort of vaccinated individuals was selected, and their vaccine potency was assessed at various time intervals following their initial vaccine administration. The study participants received booster doses as the third and fourth doses, with differing time intervals between them. The study monitored neutralizing antibody titers and other relevant parameters to assess vaccine efficacy. Results: Our findings revealed that the potency of the SARS-CoV-2 vaccine exhibited a significant decline 80 days after the initial vaccine administration. However, a longer interval of 175 days between booster injections resulted in significantly higher neutralizing antibody titers. The individuals who received the extended interval boosters exhibited a more robust immune response, suggesting that a vaccine schedule with a 175-day interval between injections may provide superior protection against SARS-CoV-2. Conclusion: This study underscores the importance of optimizing vaccine booster dosing schedules to maximize protection against SARS-CoV-2. The results indicate that a longer interval of 175 days between the third and fourth doses of the vaccine can significantly enhance the neutralizing antibody response, potentially offering improved protection against the virus. These findings have important implications for vaccine distribution and administration strategies in the ongoing battle against the SARS-CoV-2 pandemic. Further research and large-scale trials are needed to confirm and extend these findings for broader public health implications.

      • KCI등재

        Anterior Cervical Discectomy and Fusion for Hirayama Disease: A Case Report and Literature Review

        Yi-Hsuan Kuo,Chao-Hung Kuo,Wen-Cheng Huang,Jau-Ching Wu 대한척추신경외과학회 2019 Neurospine Vol.16 No.3

        Hirayama disease, a juvenile muscular atrophy of the distal upper extremity, is a rare form of cervical flexion myelopathy characterized by insidiously progressive weakness of the hands and forearm muscles (i.e., painless amyotrophy). The pathognomonic finding is a markedly forward-shifted spinal cord during neck flexion, demonstrated by dynamic magnetic resonance imaging (MRI), as in a young man with muscle atrophy in the bilateral distal upper extremities. In this report, the authors describe a 31-year-old man who had the classic radiological and clinical presentations of Hirayama disease. Since prior medical treatment had been ineffective for years, he underwent multilevel instrumented anterior cervical discectomy and fusion (ACDF) to keep his subaxial cervical spine slightly-lordotic (nonflexion). His motor evoked potential amplitude improved immediately during the operation, and there were improvements of myelopathy and a modest reversal of muscle wasting at 1 year postoperatively. Postoperative dynamic cervical spine MRI also demonstrated minimal cord compression and elimination of the venous plexus engorgement dorsal to the thecal sac. Although Hirayama disease is benign in nature and frequently self-limiting, multilevel instrumented ACDF could be a reasonable management option.

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