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Distribution of Factors Affecting Foreign Direct Investment in ASEAN Countries
Anh Thi Lan NGUYEN(Anh Thi Lan NGUYEN ),Chau Thi Minh PHAM(Chau Thi Minh PHAM ),Hanh Hong NGUYEN(Hanh Hong NGUYEN ),Dat Ngoc NGUYEN(Dat Ngoc NGUYEN ),Duy Van NGUYEN(Duy Van NGUYEN ) 한국유통과학회 2023 유통과학연구 Vol.21 No.2
Purpose: Research on attracting foreign direct investment plays an important role in ASEAN countries. ASEAN has needed FDI capital for development and integration with many developing countries. Research design, data and methodology: This study is conducted to assess the impact of factors: inflation (INF), economic growth (GDP), population (POP), and trade (TRADE) on attracting foreign direct investment (FDI) of ASEAN countries. The study will find out how factors distribution contributes to FDI attraction. The study collects data from 10 ASEAN countries from 2010 to 2020. With data collected for ten countries from 2010 to 2020, data analysis with panel data will be used in this study. The Regression with Driscoll-Kraay standard errors correction model will be used in the study. Results: Panel data analysis shows that economic growth and population positively impact FDI attraction in ASEAN countries. However, two factors: INF and TRADE, do not affect FDI. Conclusions: Countries need to focus on economic development, create many good conditions for people and domestic enterprises and create opportunities for foreign investors to pay more attention. improving the quality of domestic human resources will help to better improve the working quality factor when the demand for high-quality human resources increases.
New Dibenzocyclooctadiene Lignan from Kadsura induta and Their Cytotoxic Activities
Pham, Thi Hong Minh,Do, Tien Lam,Nguyen, Quyet Tien,Nguyen, Ngoc Tuan,Vu, Phuong Nhung,Nong, Van Hai,Phan, Van Kiem,Nguyen, Xuan Nhiem,Chau, Van Minh,Park, SeonJu,Kim, Seung Hyun Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.6
Chemical components from the leaves of Ardisia insularis and their cytotoxic activity
Nguyen Thi Hong Van,김승현,Trinh Anh Vien,Phan Van Kiem,Chau Van Minh,Nguyen Xuan Nhiem,Pham Quoc Long,Luu Tuan Anh,김난영,박선주 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.11
One new oleanane triterpene glycoside, ardinsuloside(1), and twelve known compounds, demethoxybergenin(2), norbergenin (3), bergenin (4), 4-O-galloylbergenin(5), quercitrin (6), myricitrin (7), myricetin 3-O-(300-O-galloyl)-a-L-rhamnopyranoside (8), desmanthine-2 (9), epicatechin3-O-galloyl ester (10), 30-methoxyepicatechin 3-Ogalloylester (11), gallic acid (12), and methyl galloate (13)were isolated from the leaves of Ardisia insularis. Theirstructures were established on the basis of spectral and chemicalevidence, which were in agreement with those reportedin literature. The cytotoxic activities of these compounds wereevaluated on three cancer cell lines namely A-549 (humanlung cancer), HT-29 (Human colon adenocarcinoma), andOVCAR (human ovarian carcinoma). The results revealedthat compound 1 inhibited A-549, HT-29, and OVCAR celllines with IC50 values of 8.5 ± 1.2, 16.4 ± 3.1, and13.6 ± 2.4 lM, respectively. The remaining compoundshowed weak cytotoxic activity. This result indicated thatcompound 1 could be useful in the treatment of cancer disease.
Nguyen Xuan Nhiem,Pham Hai Yen,Nguyen Thi Thanh Ngan,TRANHONG QUANG,Phan Van Kiem,Chau Van Minh,Bui Huu Tai,Nguyen Xuan Cuong,Seok Bean Song,김영호 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.4
Momordica charantia is used to treat various diseases, including inflammatory conditions. Previous reports indicated that the extract of this plant inhibits activation of nuclear transcription factor-jB (NF-jB) but activates peroxisome proliferator-activated receptor (PPAR). Additionally, cucurbitane-type triterpene glycosides are the main bioactive components of the fruit of M. charantia. Therefore, we investigated the anti-inflammatory activity of 17 cucurbitane-type triterpene glycosides (1–17) isolated from this plant. Their inhibition of NF-jB and activation of PPAR activities in HepG2 cells were measured using luciferase reporter and PPAR subtype transactivation assays. Compounds 6 and 8 were found to inhibit NF-jB activation stimulated by tumor necrosis factor-a (TNFa) in a dose-dependent manner. With 50% inhibition concentration (IC50) values of 0.4 lM, compounds 6 and 8 were more potent inhibitors than the positive control, sulfasalazine (IC50 = 0.9lM). Compounds 4, 6, and 8 also inhibited TNFa-induced expressions of inducible nitric oxide synthase and cyclooxygenase-2mRNA. However, only compound 13 significantly increased PPARc transactivation.
Triterpenoids from aerial parts of Glochidion eriocarpum.
Thu, Vu Kim,Kiem, Phan Van,Yen, Pham Hai,Nhiem, Nguyen Xuan,Tung, Nguyen Huu,Cuong, Nguyen Xuan,Minh, Chau Van,Huong, Hoang Thanh,Lau, Trinh Van,Thuan, Ngo Thi,Kim, Young Ho Natural Product Communications 2010 Natural product communications Vol.5 No.3
<P>From the aerial parts of Glochidion eriocarpum, a new triterpene, glochieriol (1), three new triterpenoid saponins, glochieriosides C - E (2 - 4), together with four known triterpenes (glochidonol, glochidiol, lupeol, and 3-epi-lupeol) were isolated by using combined chromatographic separations. The structures of the new compounds were elucidated on the basis of spectroscopic data, including FTICR-MS, 1D and 2D NMR.</P>
Kiem, Phan Van,Anh, Hoang Le Tuan,Nhiem, Nguyen Xuan,Minh, Chau Van,Thuy, Nguyen Thi Kim,Yen, Pham Hai,Hang, Dan Thuy,Tai, Bui Huu,Mathema, Vivek Bhakta,Koh, Young-Sang,Kim, Young Ho The Pharmaceutical Society of Japan 2012 Chemical & pharmaceutical bulletin Vol.60 No.2
<P>The rhizomes of <I>Hedychium coronarium</I> have been used for the treatment of inflammation, skin diseases, headache, and sharp pain due to rheumatism in traditional medicine. From this plant, two new labdanes, 15-methoxylabda-8(17),11<I>E</I>,13-trien-16,15-olide (<B>1</B>) and 16-methoxylabda-8(17),11<I>E</I>,13-trien-15,16-olide (<B>3</B>), named hedycoronens A and B, as well as four known, labda-8(17),11,13-trien-16,15-olide (<B>2</B>), 16-hydroxylabda-8(17),11,13-trien-15,16-olide (<B>4</B>), coronarin A (<B>5</B>), and corronarin E (<B>6</B>) were isolated. Their chemical structures were elucidated by mass, 1D- and 2D-nuclear magnetic resonance (NMR) spectroscopy. They were evaluated for inhibitory effects on the lipopolysaccharide (LPS)-stimulated production of pro-inflammatory cytokines in bone marrow-derived dendritic cells. Among of them, compounds <B>1</B>—<B>3</B> were potent inhibitors of LPS-stimulated interleukin-6 (IL-6) and IL-12 p40, with IC<SUB>50</SUB> ranging from 4.1±0.2 to 9.1±0.3 μ<SMALL>M</SMALL>. Compounds <B>1</B> and <B>3</B> showed moderate inhibitory activity on the tumor necrosis factor-α (TNF-α) production with IC<SUB>50</SUB> values of 46.0±1.3 and 12.7±0.3 μ<SMALL>M</SMALL>. The remains of compounds showed inactivity. These results warrant further studies concerning the potential anti-inflammatory benefits of labdane-diterpenes from <I>H. coronarium</I>.</P>