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Analysis of Toothbrushing Force on Various Brushing Method
Sang Mi Jeon,Kou ni,Sang Woo Kim,Ji Sun Kim,Ok Joon Kim,Hong Ran Choi,Ok Su Kim 대한구강악안면병리학회 2015 대한구강악안면병리학회지 Vol.39 No.1
The aim of this study was to carry out the comparative analysis of the brushing force following various brushing techniques bytoothbrush mounted pressure sensing unit. The study group consisted of 10 dental hygienist participants. The brushing forces (on buccal area of each first molar) were monitored on 8 different kinds of brushing techniques; Fones, Bass, Rolling, Scrub, Charters, stillman, Modified bass and Modified stillman. In Bass, Charters, Fones and Scrub method, force distributions showed a small gap of maximum and minimum value (Max/Min) while a big difference was noted in Modified bass, Modified stillman, Rolling and Stillman methods. Especially, the biggest difference of Max/Min value was observed in the area of lower left first molar. In conclusion, highly delicate manual skill is needed in showing big error range of force distribution. It means that careful force needs to be focused during toothbrushing instruction when a delicate manual skill was carried out.
CD137 (4-1BB) Deficiency Reduces Atherosclerosis in Hyperlipidemic Mice
Jeon, Hyung Jun,Choi, Jae-Hoon,Jung, In-Hyuk,Park, Jong-Gil,Lee, Mi-Ran,Lee, Mi-Ni,Kim, Bora,Yoo, Ji-Young,Jeong, Se-Jin,Kim, Dae-Yong,Park, Jeong Euy,Park, Hyun-Young,Kwack, KyuBum,Choi, Beom Kyu,Kwo Ovid Technologies Wolters Kluwer -American Heart A 2010 CIRCULATION - Vol.121 No.9
Choi, Jae-Hoon,Park, Jong-Gil,Jeon, Hyung-Jun,Kim, Mi-Sun,Lee, Mi-Ran,Lee, Mi-Ni,Sonn, Seong-Keun,Kim, Jae-Hong,Lee, Mun-Han,Choi, Myung-Sook,Park, Yong-Bok,Kwon, Oh-Seung,Jeong, Tae-Sook,Lee, Woo-Son Korean Society for Biochemistry and Molecular Bion 2011 Experimental and molecular medicine Vol.43 No.8
A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of 5-(4-hydroxy-2,3,5-trimethylbenzylidene) thiazolidin-2,4-dione (HMB-TZD), a benzylidenethiazole analog, and its potential mechanism of action in LDL receptor-deficient ($Ldlr^{-/-}$) mice. HMB-TZD Treatment reduced leukotriene $B_4$ ($LTB_4$) production significantly in RAW264.7 macrophages and SVEC4-10 endothelial cells. Macrophages or endothelial cells pre-incubated with HMB-TZD for 2 h and then stimulated with lipopolysaccharide or tumor necrosis factor-alpha (TNF-${\alpha}$) displayed reduced cytokine production. Also, HMB-TZD reduced cell migration and adhesion in accordance with decreased proinflammatory molecule production $in$ $vitro$ and $ex$ $vivo$. HMB-TZD treatment of 8-week-old male $Ldlr^{-/-}$ mice resulted in significantly reduced atherosclerotic lesions without a change to plasma lipid profiles. Moreover, aortic expression of pro-atherogenic molecules involved in the recruitment of monocytes to the aortic wall, including TNF-${\alpha}$, MCP-1, and VCAM-1, was downregulated. HMB-TZD also reduced macrophage infiltration into atherosclerotic lesions. In conclusion, HMB-TZD ameliorates atherosclerotic lesion formation possibly by reducing the expression of proinflammatory molecules and monocyte/macrophage recruitment to the lesion. These results suggest that HMB-TZD, and benzylidenethiazole analogs in general, may have therapeutic potential as treatments for atherosclerosis.
해초추출물 (Petalonia binghamiae)이 저밀도지질단백질 결손 생쥐에서 혈중 콜레스테롤에 미치는 영향
손성근 ( Seong Keun Sonn ),박종길 ( Jong Gil Park ),전형준 ( Hyung Jun Jeon ),이미란 ( Mi Ran Lee ),이미니 ( Mi Ni Lee ),고희철 ( Hee Chul Ko ),강성일 ( Seong Il Kang ),이문한 ( Mun Han Lee ),김세재 ( Se Jae Kim ),오구택 ( Goo Tea 한국지질동맥경화학회(구 한국지질학회) 2008 韓國脂質學會誌 Vol.18 No.2
poster : Null Mutation of Peroxiredoxin 2 Exacerbates Early Atherosclerosis
( Jong Gil Park ),( Jae Hoon Choi ),( Sun Hee Yim ),( Hyung Jun Jeon ),( Mi Ran Lee ),( Mi Ni Lee ),( Ji Young Yoo ),( Chun Gi Kim ),( Young Myeong Kim ),( Sue Goo Rhee ),( Sang Won Kang ),( Dae Yeul 한국지질동맥경화학회 ( 구 한국지질학회 ) 2006 한국지질동맥경화학회 추계학술발표논문집 Vol.2006 No.-