Volatilization of Nerolidol in Tea and Tea-soup

Yuan-Xu Shi,Ya-Ting Lu,Jie Lin,Xiao-Chang Wang 한국차학회 2015 한국차학회지 Vol.- No.S

Nerolidol is one of most important content in tea aroma, especially in Oolong tea. This experiment focuses on the impact of time and medium on nerolidol volatilization. The results of nerolidol volatilization with infusion time showed that the peak areas of nerolidol increased from 1 to 3 min, then decreased. The maximum peak area of nerolidol volatilization was 25630.78 at 3 min. Tea polyphenol had strong promotion impact on fragrant compound volatize, caffeine had limited impact on volatilization, while polysaccharide inhibited nerolidol volatilization.

Abundance and host-seeking activity of the biting midge, Forcipomyia taiwana (Diptera: Ceratopogonidae)

Chang-Liang Shih,Quei-Min Liao,Ya-Yuan Wang,Wu-Chun Tu 한국응용곤충학회 2019 Journal of Asia-Pacific Entomology Vol.22 No.4

The abundance and host-seeking activity of the biting midge, Forcipomyia taiwana (Shiraki), were measured in Central Taiwan at 418 locations with low, medium, and high densities using a human-bait method. Abundance estimates at 10 min after sampling commenced were comparable to longer sampling periods of 20 min, allowing a shorter 10 min sampling period to be used throughout. Host-seeking F. taiwana females were only active during daylight and biting activity did not occur after sunset. The diurnal activity of host-seeking females changed seasonally, beginning at around 07:00–08:00 during the spring equinox, summer solstice, and autumnal equinox, whereas activity began an hour later in winter. Most females were collected during 10:00–16:00, with a peak abundance during 13:00–15:00. Blood-sucking activity of female F. taiwana were positively correlated with ambient temperature with a minimum threshold of 18 °C. When different years, seasons, trapping times, environmental factors, and female adults trapped were analyzed using multiple regression model, the results showed that all these factors contributed to the regression model and the determination coefficient (R 2 ) of this multiple regression model was 0.81.

CCR6 Is a Predicting Biomarker of Radiosensitivity and Potential Target of Radiosensitization in Rectal Cancer

Hui Chang,Jia-wang Wei,Ya-lan Tao,Pei-rong Ding,Yun-fei Xia,Yuan-hong Gao,Wei-wei Xiao 대한암학회 2018 Cancer Research and Treatment Vol.50 No.4

Purpose This study aimed to explore the functions and mechanisms of C-C motif chemokine receptor 6 (CCR6), a gene associated with progression and metastasis of colorectal cancer (CRC), in radiosensitivity of rectal cancer (RC). Materials and Methods RNA sequencing and immunohistochemical analysis on CCR6 expression were performed in pretreatment tissues of RC patients exhibiting different therapeutic effects of radiotherapy. Colonogenic survival assay was conducted in different CRC cell lines to assess their radiosensitivity. And the impact of CCR6 expression on radiosensitivity was validated through RNA interference. The DNA damage repair (DDR) abilities of cell lines with different CCR6 expression were evaluated through immunofluorescence-based H2AX quantification. Results The CCR6 mRNA level was higher in patients without pathologic complete remission (pCR) than in those with pCR (fold changed, 2.11; p=0.004). High-level expression of CCR6 protein was more common in the bad responders than in the good responders (76.3% vs. 37.5%, p < 0.001). The CRC cell lines with higher CCR6 expression (LoVo and sw480) appeared to be more radioresistant, compared with the sw620 cell line which had lower CCR6 expression. CCR6 knockdown made the LoVo cells more sensitive to ionizing radiation (sensitization enhancement ratio, 1.738; p < 0.001), and decreased their DDR efficiency. Conclusion CCR6 might affect the RC radiosensitivity through DDR process. These findings supported CCR6 as a predicting biomarker of radiosensitivity and a potential target of radiosensitization for RC patients.

Weibull Kinetic Modeling and Nutritional Effects of High-hydrostatic-pressure Sterilization of Soft-packing Boiled Bamboo Shoots

Long Yuan,Li-xin Lu,Ya-li Tang,Chang-feng Ge 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.2

Application of high-hydrostatic-pressure (HHP) sterilization technology to boiled bamboo shoots was preliminarily discussed. An improved Weibull model that considered pressure and time as independent variables simultaneously for simulating the sterilization result was obtained by fitting the microbial lethal curves with high precision (R2>0.98). HHP sterilization parameters could be calculated using this model with a certain disinfection rate. For a sterilization rate of 99.5%, treatment with a pressure of 400 MPa for 6 min or 500 MPa for 3 min at room temperature could exterminate all pathogenic microorganisms in boiled bamboo shoots, and control the total number of colonies at a low level below 100 CFU/g. Comparisons of the effects of HHP, high-pressure steam and microwave on the softness and contents of soluble protein and vitamin C of samples were also made. The results showed that the extent of damage of the products’ original quality caused by HHP sterilization was less than that caused by the thermal and microwave treatment processes with equivalent sterilization percentages.

TIAM2 Enhances Non-small Cell Lung Cancer Cell Invasion and Motility

Zhao, Zheng-Yuan,Han, Chen-Guang,Liu, Jun-Tao,Wang, Chang-Lei,Wang, Yi,Cheng, Li-Ya Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

Background: TIAM2, a Rac guanine nucleotide exchange factor, is closely associated with cell adherence and migration. Here, we aimed to investigate the role of TIAM2 in non-small cell lung cancer (NSCLC) cells. Materials and Methods: A small interference RNA (siRNA) was introduced to silence the expression of TIAM2. Invasion and motility assays were then performed to assess the invasion and motility potential of NSCLC cells. GST-pull down assays were used to detect activation of Rac1. Results: TIAM2 was highly expressed in NSCLC cells. Knockdown of TIAM2 inhibited the invasion and motility, and suppressed activation of Rac1. Further experiments demonstrated that knockdown of TIAM2 could up-regulate the expression of E-cadherin, and down-regulate the expression of MMP-3, Twist and Snail. Conclusions: Our data suggest that TIAM2 can promote invasion and motility of NSCLC cells. Activation of Rac1 and regulation of some EMT/invasion-related genes may be involved in the underlying processes.

Screening of Nitrosamine Impurities in Sartan Pharmaceuticals by GC-MS/MS

( Shu-Han Chang ),( Hui-Yu Ho ),( Chi-Zong Zang ),( Ya-Hui Hsu ),( Mei-Chih Lin ),( Su-Hsiang Tseng ),( Der-Yuan Wang ) 한국질량분석학회 2021 Mass spectrometry letters Vol.12 No.2

Probable human carcinogenic compounds nitrosamines, have been detected as by-product impurities in sartan pharmaceuticals in recent years which has drawn worries for medication safety. To provide a sensitive and effective method for the quality control of sartan pharmaceuticals, this study established a feasible gas chromatography-tandem mass spectrometry (GC-MS/MS) method for simultaneous determination of 13 nitrosamines. The target analytes were separated on a DB-WAX Ultra Inert column (30 m × 0.25 mm; i.d., 0.25 μm) and were then subjected to electron impact ionization in multiple reaction monitoring mode. The established method was validated and further employed to analyze authentic samples. Limits of detection (LODs) and limits of quantification (LOQs) of the 13 nitrosamines were 15-250 ng/g and 50-250 ng/g, respectively, which also exhibited intra-day and inter-day accuracies of 91.4-104.8%, thereby satisfying validation criteria. Five nitrosamines, viz., Nnitrosodiethylamine, N-nitrosodimethylamine, N-nitrosodiphenylamine, N-nitrosomorpholine, and N-nitrosopiperidine were detected at concentrations above their LODs in 68 positive samples out of 594 authentic samples from seven sartans.

中国魏晋南北朝诗歌中的海洋意象初探

晁?若(Chao, Ya-Ruo),金昌?(Kim, Chang-Gyeong),袁?莉(Yuan, Xiao-Li) 동북아시아문화학회 2018 동북아 문화연구 Vol.1 No.57

As an important concept in literary theory, imagery theory has undergone a long process of development. But there are different characteristics in ancient and modern times, western countries and China. Western imagery is more concerned with Xiang, whereas the Chinese classical imagery theory focuses on Yi,it argues that images are the unification of subjective feelings and objects. This paper mainly uses Chinese classical imagery theory to analyze ocean imagery. Based on the development of imagery theory, we firstly defined the definition of ocean imagery as follows: It is the visible phenomena associated with the ocean which can be utilized to describe, imply, express emotions and ambitions by the poets. Then we choose the wei jin, Northern and Southern Dynasties which is the turning point in the development of Chinese literature as our range of study and select the most closely related style of writing -- poetry as our transverse research center, take the electronic data library and paper literature as basic research data to make the detailed statistics and rough structural classification. In terms of basic meaning, it can be divided into seven categories: the first category is the imagery of the basic meaning generally refer to the sea; the second is the basic meaning of sea water and its existence; the third is the imagery of the basic meaning associated with the sea area; the forth is the imagery of the basic meaning associated with maritime life; the fifth category is the imagery of the basic meaning associated with marine organism; the sixth class is the image related to the ocean landscape; The seventh category of an imagery is related to marine myth or religion. In terms of structure, the ocean imagery can be divided into single and complex form. At last, we make the functional classification of ocean imagery based on the specific poems: descriptive ocean imagery, metaphorically ocean imagery and symbolic ocean imagery.

Effect of Tea on Resistance to Type 2 Diabetes

Peng Lu,Kai Fan,Ya-Ting Lu,Yuan-Xu Shi,Dong-Mei Fan,Xiao-Chang Wang 한국차학회 2015 한국차학회지 Vol.- No.S

Insulinotropic hormone glucagon-like peptide-1 (GLP-1) degrades rapidly under the catalytic of dipeptidyl peptidase IV (DPP-IV). Consequently, DPP-IV which is widely expressed in small intestine takes a key role in the prevention and treatment of Type 2 Diabetes. To identify the capability of anti-type 2 diabetes by tea, the inhibition of different types of Chinese teas on DPP-IV was tested. The inhibitory ratio of Buddha Longjing is 31.74%, Tangji Gaoshan Tea is 62.08% (p < 0.01), Yunnan black tea is 66.29% (p < 0.01), Lapsang souchon is 76.40% (p <0.01), Dahongpao is 62.08% (p < 0.01), Tieguanyin is 66.85% (p < 0.01), Moganhuangya is 65.45% (p < 0.01),Huoshanhuangya is 50.56% (p < 0.05).

Structural relationships between safety attachment, experiential co-creation and future experiential intentions in the tourism industry

Wu Hung-Che,Chang Ya-Yuan,Wu Tsung-Pao 한국마케팅과학회 2023 마케팅과학연구 Vol.33 No.1

This paper aims to explore the relationships between the dimensions of safety attachment, the dimensions of experiential cocreation and future experiential intentions. A convenience sample of 505 tourists who had departed from Hartsfield–Jackson Atlanta International Airport via direct flights to a destination outside the USA during the 2019-nCoV (COVID-19) outbreak was surveyed. The results will assist tourism managers in developing and implementing market-orientated service strategies to increase safety identity, safety dependence, safety affect, safety social bonding, experiential trust, experiential commitment and experiential connection in order to enable tourists to have future intentions to experience the destination during the COVID-19 outbreak. Findings are generalizable only to the tourism industry investigated.

Moldable Job Scheduling for HPC as a Service with Application Speedup Model and Execution Time Information

Kuo-Chan Huang,Tse-Chi Huang,Mu-Jung Tsaia Hsi-Ya Chang,Yuan-Hsin Tung 한국정보기술융합학회 2013 JoC Vol.4 No.4