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        Ecological No-tillage Technology of Sloping Tea Garden in China

        Dong-Mei Fan,Kai Fan,Peng Lu,Xiao-Chang Wang 한국차학회 2015 한국차학회지 Vol.- No.S

        The majority of sloping tea gardens in China are now short of effective management because of the limitation of labor force, therefore tea quality is hard to guarantee and the tea industry might be frustrated. Thus a new ecological no-tillage technique (abbreviation for ENT) was put forward, the application of this technique was developed on the basis of some reconstructions in current sloping tea gardens including two key steps: 1) remolding present sloping tea gardens into semi-trapezoidal one by a special ditch; 2) preserving pruning brunches and organic fertilizers into those ditches to form an organic cover layer on soil. This no-tillage technique could significantly reduce soil erosion as well as promote the formation of organic matters on soil surface in 3-5 years. Comparing with the conventional tillage measures, ENT could save about 40% fertilization and 50% labor-cost. Combine with assistant managements, the ecological no-tillage technology could not only effectively recover ecosystem, but also depress plant diseases and insect pests. Improvement on tea production and tea quality especially tea aroma are also observed. It is convincible that ENT has considerable advantages in cost-savings and production efficiency improvement in sloping tea gardens, which makes it one of the reference management choices for future sustainable development.

      • Hypoxia-Inducible Factor 1 Promoter-Induced JAB1 Overexpression Enhances Chemotherapeutic Sensitivity of Lung Cancer Cell Line A549 in an Anoxic Environment

        Hu, Ming-Dong,Xu, Jian-Cheng,Fan, Ye,Xie, Qi-Chao,Li, Qi,Zhou, Chang-Xi,Mao, Mei,Yang, Yu Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5

        The presence of lung cancer cells in anoxic zones is a key cause od chemotherapeutic resistance. Thus, it is necessary to enhance the sensitivity of such lung cancer cells. However, loss of efficient gene therapeutic targeting and inefficient objective gene expression in the anoxic zone in lung cancer are dilemmas. In the present study, a eukaryotic expression plasmid pUC57-HRE-JAB1 driven by a hypoxia response elements promoter was constructed and introduced into lung cancer cell line A549. The cells were then exposed to a chemotherapeutic drug cis-diamminedichloroplatinum (C-DDP). qRT-PCR and western blotting were used to determine the mRNA and protein level and flow cytometry to examine the cell cycle and apoptosis of A549 transfected pUC57-HRE-JAB1. The results showed that JAB1 gene in the A549 was overexpressed after the transfection, cell proliferation being arrested in G1 phase and the apoptosis ratio significantly increased. Importantly, introduction of pUC57-HRE-JAB1 significantly increased the chemotherapeutic sensitivity of A549 in an anoxic environment. In conclusion, JAB1 overexpression might provide a novel strategy to overcome chemotherapeutic resistance in lung cancer.

      • KCI등재후보

        Effect of Tea on Resistance to Type 2 Diabetes

        Peng Lu,Kai Fan,Ya-Ting Lu,Yuan-Xu Shi,Dong-Mei Fan,Xiao-Chang Wang 한국차학회 2015 한국차학회지 Vol.- No.S

        Insulinotropic hormone glucagon-like peptide-1 (GLP-1) degrades rapidly under the catalytic of dipeptidyl peptidase IV (DPP-IV). Consequently, DPP-IV which is widely expressed in small intestine takes a key role in the prevention and treatment of Type 2 Diabetes. To identify the capability of anti-type 2 diabetes by tea, the inhibition of different types of Chinese teas on DPP-IV was tested. The inhibitory ratio of Buddha Longjing is 31.74%, Tangji Gaoshan Tea is 62.08% (p < 0.01), Yunnan black tea is 66.29% (p < 0.01), Lapsang souchon is 76.40% (p <0.01), Dahongpao is 62.08% (p < 0.01), Tieguanyin is 66.85% (p < 0.01), Moganhuangya is 65.45% (p < 0.01),Huoshanhuangya is 50.56% (p < 0.05).

      • Effect of Metal (Mn, Ti) Doping on NCA Cathode Materials for Lithium Ion Batteries

        Wan, Dao Yong,Fan, Zhi Yu,Dong, Yong Xiang,Baasanjav, Erdenebayar,Jun, Hang-Bae,Jin, Bo,Jin, En Mei,Jeong, Sang Mun Hindawi Limited 2018 Journal of nanomaterials Vol.2018 No.-

        <P>NCA (LiNi0.85Co0.10Al0.05-<I>x</I> M<I>x</I>O2, M=Mn or Ti, <TEX>$ x$</TEX> < 0.01) cathode materials are prepared by a hydrothermal reaction at 170°C and doped with Mn and Ti to improve their electrochemical properties. The crystalline phases and morphologies of various NCA cathode materials are characterized by XRD, FE-SEM, and particle size distribution analysis. The CV, EIS, and galvanostatic charge/discharge test are employed to determine the electrochemical properties of the cathode materials. Mn and Ti doping resulted in cell volume expansion. This larger volume also improved the electrochemical properties of the cathode materials because Mn<SUP>4+</SUP> and Ti<SUP>4+</SUP> were introduced into the octahedral lattice space occupied by the Li-ions to expand the Li layer spacing and, thereby, improved the lithium diffusion kinetics. As a result, the NCA-Ti electrode exhibited superior performance with a high discharge capacity of 179.6 mAh g<SUP>−1</SUP> after the first cycle, almost 23 mAh g<SUP>−1</SUP> higher than that obtained with the undoped NCA electrode, and 166.7 mAh g<SUP>−1</SUP> after 30 cycles. A good coulombic efficiency of 88.6% for the NCA-Ti electrode is observed based on calculations in the first charge and discharge capacities. In addition, the NCA-Ti cathode material exhibited the best cycling stability of 93% up to 30 cycles.</P>

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