http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Angel Chao,Yi-Hao Lin,Lan-Yan Yang,Ren-Chin Wu,Wei-Yang Chang,Pi-Yueh Chang,Shih-Cheng Chang,Chiao-Yun Lin,Huei-Jean Huang,Cheng-Tao Lin,Hung-Hsueh Chou,Kuan-Gen Huang,Wen-Ling Kuo,Ting-Chang Chang,Ch 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3
Objective: The characteristics of patients with metachronous breast and ovarian malignancies and the pathogenic role of BRCA1/2 mutations remain poorly understood. We investigated these issues through a review of hospital records and nationwide Taiwanese registry data, followed by BRCA1/2 mutation analysis in hospital-based cases. Methods: We retrospectively retrieved consecutive clinical records of Taiwanese patients who presented with these malignancies to our hospital between 2001 and 2017. We also collected information from the Data Science Center of the Taiwan Cancer Registry (TCR) between 2007 and 2015. Next-generation sequencing and multiplex ligation-dependent probe amplification were used to identify BRCA1/2 mutations and large genomic rearrangements, respectively. When BRCA1/2 mutations were identified in index cases, pedigrees were reconstructed and genetic testing was offered to family members. Results: A total of 12,769 patients with breast cancer and 1,537 with ovarian cancer were retrieved from our hospital records. Of them, 28 had metachronous breast and ovarian malignancies. We also identified 113 cases from the TCR dataset. Eighteen hospital-based cases underwent BRCA1/2 sequencing and germline pathogenic mutations were detected in 7 patients (38.9%, 5 in BRCA1 and 2 in BRCA2). All BRCA1/2 mutation carriers had ovarian high-grade serous carcinomas. Of the 12 patients who were alive at the time of analysis, 5 were BRCA1/2 mutation carriers. All of them had family members with BRCA1/2-associated malignancies. Conclusions: Our results provide pilot evidence that BRCA1/2 mutations are common in Taiwanese patients with metachronous breast and ovarian malignancies, supporting the clinical utility of genetic counseling.
Chih-Chang Chang,Jau-Ching Wu,Chin-Chu Ko,Hsuan-Kan Chang,Yi-Hsuan Kuo,Chao-Hung Kuo,Tsung-Hsi Tu,Wen-Cheng Huang 대한척추신경외과학회 2022 Neurospine Vol.19 No.4
Objective: Diseases of the craniovertebral junction (CVJ) are commonly associated with deformity, malalignment, and subsequent myelopathy. The misaligned CVJ might cause compression of neuronal tissues and subsequently clinical symptoms. The triangular area (TA), measured by magnetic resonance imaging/images (MRI/s), is a novel measurement for quantification of the severity of compression to the brain stem. This study aimed to assess the normal and pathological values of TA by a comparison of patients with CVJ disease to age- and sex-matched controls. Moreover, postoperative TAs were correlated with outcomes. Methods: Consecutive patients who underwent surgery for CVJ disease were included for comparison to an age- and sex-matched cohort of normal CVJ persons as controls. The demographics, perioperative information, and pre- and postoperative 2-year cervical MRIs were collected for analysis. Cervical TAs were measured and compared. Results: A total of 201 patients, all of whom had pre- or postoperative MRI, were analyzed. The TA of the CVJ deformity group was larger than the healthy control group (1.62 ± 0.57 cm2 vs. 1.01 ± 0.18 cm2 , p < 0.001). Moreover, patients who had combined anterior odontoidectomy and posterior laminectomy with fixation had the greatest reduction in the TA (1.18 ± 0.58 cm2 ). Conclusion: In CVJ deformity, the measurement of the cervical TA could indicate the severity of brain stem compression. After surgery, the TA had a varying degree of improvement, which could represent the efficacy of surgery.
SF?와 제조공기(I-Air)의 압력별 절연파괴특성 비교
이창욱(Chang-Wook Lee),김영수(Young-Su Kim),方亞偉(Ya-Wei Fang),이창훈(Chang-Hun Lee),김도석(Do-Seok Kim),常超(Chao Chang),최은혁(Eun-Hyuck Choi),임창호(Chang-Ho Lim),이광식(Kwang-Sik Lee) 한국조명·전기설비학회 2006 한국조명·전기설비학회 학술대회논문집 Vol.2006 No.11월
본 연구는 현재 전력설비에 사용되고 있는 SF?가스의 대체 절연가스로 제조공기(Ⅰ-Air)의 절연파괴특성 연구를 위하여 모의 GIS 챔버와 AC 300[㎸] 전원장치로 교류전압을 인가하여 연구를 수행하였다. 침 전극 대 평판전극을 이용하여 SF?가스와 I-Air의 절연내력을 비교하기 위해서 3, 4 및 5[atm]까지 가스의 압력변화를 주었고 각 압력별 전극간거리(d)에 따른 절연파괴전압(V<SUB>B</SUB>)을 연구하였다.
Challenges to Next Generation Services in IP Multimedia Subsystem
Chang, Kai-Di,Chen, Chi-Yuan,Chen, Jiann-Liang,Chao, Han-Chieh Korea Information Processing Society 2010 Journal of information processing systems Vol.6 No.2
The trend of Next Generation Networks' (NGN) evolution is towards providing multiple and multimedia services to users through ubiquitous networks. The aim of IP Multimedia Subsystem (IMS) is to integrate mobile communication networks and computer networks. The IMS plays an important role in NGN services, which can be achieved by heterogeneous networks and different access technologies. IMS can be used to manage all service related issues such as Quality of Service (QoS), Charging, Access Control, User and Services Management. Nowadays, internet technology is changing with each passing day. New technologies yield new impact to IMS. In this paper, we perform a survey of IMS and discuss the different impacts of new technologies on IMS such as P2P, SCIM, Web Service and its security issues.
Chao, Zhe,Zheng, Xin-Li,Sun, Rui-Ping,Liu, Hai-Long,Huang, Li-Li,Cao, Zong-Xi,Deng, Chang-Yan,Wang, Feng Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.7
Epigenetic processes in the development of skeletal muscle have been appreciated for over a decade. DNA methylation is a major epigenetic modification important for regulating gene expression and suppressing spurious transcription. Up to now, the importance of epigenetic marks in the regulation of Pax7 and myogenic regulatory factors (MRFs) expression is far less explored. In the present study, semi-quantitative the real-time polymerase chain reaction (RT-PCR) analyses showed MyoD and Myf5 were expressed in activated and quiescent C2C12 cells. MyoG was expressed in a later stage of myogenesis. Pax7 was weakly expressed in differentiated C2C12 cells. To further understand the regulation of expression of these genes, the DNA methylation status of Pax7, MyoD, and Myf5 was determined by bisulfite sequencing PCR. During the C2C12 myoblasts fusion process, the changes of promoter and exon 1 methylation of Pax7, MyoD, and Myf5 genes were observed. In addition, an inverse relationship of low methylation and high expression was found. These results suggest that DNA methylation may be an important mechanism regulating Pax7 and MRFs transcription in cell myogenic differentiation.
Chang-Wei Zhang,Zhi-Gang Yang,Xiao-Dong Xie,Chao-Hua Wang,Chao You,Wei Li 대한의학회 2010 Journal of Korean medical science Vol.25 No.4
Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder. Pseudoaneurysms formation and rupture is an unusual complication of neurofibromatosis. To date, pseudoaneurysm of the internal pudendal artery associated with NF-1 has not been reported. In this article, we present a 62-yr-old man with NF-1 suffering from spontaneous hematoma of the perinea and scrotum. A digital substraction angiography disclosed a ruptured pseudoaneurysm of the right internal pudendal artery, which was successfully managed with transcatheter embolization.
Giant Cavernous Aneurysm Associated with a Persistent Trigeminal Artery and Persistent Otic Artery
Chang-wei Zhang,Xiao-dong Xie,Zhi-gang Yang,Chao-hua Wang,Chao You,Bo-yong Mao,Min He,Hong Sun 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.5
Primitive trigeminal artery (PTA) and primitive otic artery (POA) is a very rare entity in adult life. We present a case of PTA and POA associated with a giant unruptured cavernous aneurysm in a 54-year-old woman. The PTA and the POA arose from the sac of the aneurysm directly, which greatly complicated endovascular therapy management.
LOCALIZATION OF A RAIL ROBOT IN GREENHOUSE BASED ON MULTI-SENSORS
Chao Chang,Yan Li,Jang-Myung Lee 제어로봇시스템학회 2010 제어로봇시스템학회 국내학술대회 논문집 Vol.2010 No.5
In this paper, we present a method for localization of a rail Autonomous Pesticide Spraying Robot for working in greenhouse using a multi-sensors system. The proposed localization method utilizes ultrasonic, inductive proximity and vision sensors. The vision sensors are used to gather the plant image, the edge of plants can gain through the image segmentation algorithm and the edge detection algorithm. And ultrasonic sensors supply the distance information from the greenhouse walls to the robot. After fusing the data of vision sensors and ultrasonic sensors, the edge of entire rows of plant could be measured. The inductive proximity sensors supply the position information from the robot to the edge and turning of rail. By processing the signals coming from these sensors, it can be identified the position relatives between the robot and the plant. The robot is designed for eliminating pests which live on plant leaves precisely. On the basis of the position relatives, the robot executes different operations, such as running, beginning scanning leaf, stopping scanning and so on. Experiments demonstrate the effectiveness of the proposed method in real world applications.
A Theory Thermal Growth Control Techniques of High Speed Spindles
Chang,Ching-Feng,Ling,Chao-Shui,Chao, Ching-Yi,Chen, Jin-Jia,Chen,Tsair-Rong 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
A motorized high speed spindle has very complicated dynamics consisting of non-stationary and speed-related thermal characteristics. Many studies have been reported with different designs to control or monitor spindle’s thermal growth with limited results, whereas the application of High Speed Machining (HSM) demands “zero tolerance”no matter the range of speed or material to be machined. This paper proposes a direct displacement measuring system, which is a considerable improvement as compared with many taking inaccurate readings through a traditional thermo coupler, to accurately monitor and compensate the thermal growth associated with motorized high speed spindles. This direct displacement measuring system optimizing a high speed synchronous feedback system will meet the tolerance and performance expected in HSM applications. Based on the introduction of Foucault current, a design for an accurate thermal growth is outlined.