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Pang Hua Chai,Sam Chang,David Cawthorpe 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.2
Objective The purpose of this study was to test the hypothesis that a significant temporal relationship exists between asthma and attention deficit hyperactivity disorder (ADHD). Methods The population dataset consisted of 95,846,511 physician diagnoses for 768,460 (46% male) individuals spanning 1993-2010. Four groups were labeled as having neither Asthma nor ADHD, Asthma only, ADHD only, or both Asthma and ADHD and formed the basis of calculating the odds ratios for each sex describing the association of Asthma and ADHD by age, and, in addition, a prospective sample age (<5 years) between 1993 and 1996 was utilized to evaluate the temporal association between Asthma and ADHD. Results There was a significant relationship between ADHD and Asthma within the age strata of the sample, one from the cohort and two from the whole sample. When both ADHD and Asthma were diagnosed in the same patients, the age was younger in both cross-sectional and prospective cohort samples. ADHD arose significantly more often after Asthma in the cross-sectional samples stratified on age and in the prospective cohort sample. Conclusion The results are consistent with previous literature where ADHD has been linked to allergic diseases, such as asthma.
A novel ultrasonic reactor for continuous production of biodiesel from waste acid oil
Hua-Sheng Zou,Jun Chai 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.2
FAME was produced by a two-step in-situ transesterification of acid oil (AO) with methanol in a novel continuous flow ultrasonic reactor system composed of four ultrasonic reactors with different frequency. The hydrodynamic behavior of the reactor was investigated by a step response technique, and the effect of ultrasonic frequency on mono-alkyl esters of long chain fatty acids (FAMEs) formation was also investigated. The production process includes an in-situ sulfuric acid-catalyzed esterification of AO with methanol in the first two ultrasonic reactors successively followed by an in-situ base-catalyzed transesterification in the other two ultrasonic reactors. The AO initial free fatty acids (FFA) content about 17.5 w% was cut down to less than 1 w% by sulfuric acid-catalyzed esterification. FAME yields in excess of 97.0% identified by gas chromatography/mass spectrometry (GC/MS) were obtained by the two-step in-situ reaction. The maximum and minimum volumetric productivity could reach 13.76 L·h−1 and 10.24 L·h−1 respectively.
Anti-allergic Effect of Fructus amomi on Ovalbumin-induced Asthma Mice Model
Chun Hua Piao,Yan Jing Fan,Thi Van Nguyen,Zhen Nan Yu,Hee Soon Shin,Chang Ho Song,Ok Hee Chai 대한체질인류학회 2021 대한체질인류학회지 Vol.34 No.2
Despite studies on the anti-inflammatory effect of Fructus amomi, mature fruit of Amomum villosum Lour, have been getting increasing extensively, it remains unknown about the detailed effects of F. amomi on ovalbumin (OVA)-induced mouse asthma model. In this study, we examined the effect of F. amomi on OVA-induced asthma by analyzing Th1/Th2 cytokine production, histopathologic changes, and focusing on the NF-κB signaling. Oral administration of F. amomi reduced the number of inflammatory cells especially eosinophils and improved airway and pulmonary inflammation in the lungs of OVA-challenged mice. In addition, F. amomi significantly downregulated the overproduction of tumor necrosis factor-α, IL-1β, IL-4, IL-5 and the levels of OVA-specific both IgE and IgG1 and increased the secretion of interferon-γ and OVA-specific IgG2a. Moreover, F. amomi suppressed the increase of total NF-κB level and the phosphorylation of IκB-α and NF-κB by OVA. F. amomi may have therapeutic effect for allergic asthma by modulating Th1/Th2 cytokine imbalance and inhibiting NF-κB signaling activation.
Shi, Hua-Ping,Zhang, Jun,Shang, Xue-Chai,Xie, Xin-You Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Although there have been many studies investigating possible associations between the C1653T mutation and risk of HCC, the results have been inconsistent. We conducted searches of the published literature in Pubmed and Embase databases up to January 2013. Seventeen studies with a total of 1,085 HCC cases and 1,365 healthy controls were retrieved. We found a significant association between the C1653T mutation and HCC risk (OR = 2.01, 95%CI= 1.49-2.70). In the subgroup analysis by ethnicity, a significant association was also found in Asians (OR = 2.07, 95%CI= 1.71-2.51). In subgroup analysis by HBV genotype, B and C were linked with development of HCC (B:OR = 2.21, 95%CI= 1.13-4.34; C:OR = 2.26, 95%CI= 1.61-3.16). However, no significant association was found between the C1653T mutation and HCC risk in HBeAg positive cases. In conclusion, this meta-analysis suggests that the C1653T mutation may be associated with susceptibility to HCC.
Energy efficiency onboard hydraulic power for quadruped robot based on high-low double pumps supply
Zisen Hua,Zhiwei Zhang,Hui Chai,Yibin Li,Xianhua Li,Yaru Sun 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.9
This work presents a high energy efficiency onboard hydraulic system for quadruped robot. Firstly, based on the rhythmic motion and mechanical characteristics of leg joints, the energy supply mode that supplies low-pressure oil and high-pressure oil separately for the swing phase and supporting phase is used, and the switch between different oil circuits for each legs is implemented by two digital on-off valves. What’s more, to obtain the pressure dynamics characteristics and energy consumption model, the mathematical models is deduced, and the analysis results illustrates that a better rate response can be achieved by adjusting time offset reasonable properly. Finally, the simulations and experiments are conducted to prove that the proposed system shows better energy efficiency compared with that of single pump supply pressure system, meanwhile, the fast dynamic response and the high tracking accuracy are also maintained.
Lyu, Lulu,Chai, Hua,Seong, Kwang-dong,Lee, Chaedong,Kang, Jeongmin,Zhang, Wang,Piao, Yuanzhe Elsevier 2018 ELECTROCHIMICA ACTA Vol.291 No.-
<P><B>Abstract</B></P> <P>Carbonaceous materials derived from a variety of cheap and sustainable biomass have shown great potential as conductive substrates for the coating of pseudocapacitive materials. In this study, yeast-derived N-doped carbon microsphere/polyaniline (YC/PANI) composites are synthesized by an <I>in situ</I> polymerization approach, using yeasts as the carbon source and structural template. The self-templated hollow YC with good conductivity has many active sites for anchoring PANI, and alleviates the structure destruction caused by the redox reaction of PANI. Accordingly, the YC/polyaniline composite as a supercapacitor electrode exhibits a high specific capacitance (500 F g<SUP>−1</SUP> at a current density of 1 A g<SUP>−1</SUP>) and good rate capability in a three-electrode system. Additionally, the symmetric supercapacitor of the YC/polyaniline composite delivers a high capacitance (100 F g<SUP>−1</SUP> at 1 A g<SUP>−1</SUP>) and remarkable cycle life (95.4% of the initial capacitance maintenance after 5000 cycles). The uniform coating of PANI nanowires and robust structure stability of composites are responsible for excellent electrochemical properties.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Yeast-derived carbon microsphere/polyaniline composites are synthesized as electrode materials for supercapacitors. </LI> <LI> The optimized electrode exhibits a high specific capacitance and a favorable rate capability. </LI> <LI> The hollow and robust microspherical architecture of the composite ensures the long-term cycling stability. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>