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Risk Factors Leading to Radical Cystectomy in Patients Who Had Undergone Nephroureterectomy
Janghui Lee(이장희),Bumjin Lim(임범진),Dalsan You(유달산),In Gab Jeong(정인갑),Cheryn Song(송채린),Jun Hyuk Hong(홍준혁),Choung-Soo Kim(김청수),Hanjong Ahn(안한종),Bumsik Hong(홍범식) 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.4
Purpose: To identify the risk factors leading to radical cystectomy in patients who had undergone nephroureterectomy (NUx). Materials and Methods: We retrospectively reviewed the medical records of patients with upper tract urothelial carcinoma who underwent NUx during 2011–2019 and excluded patients with metastatic cancer. In total 646 patients were included in this study; of these, 532 had no previous bladder cancer history. Follow-up was performed every 3 months for 2 years after NUx was administered, and recurrence was confirmed using cystoscopy, urine cytology, computed tomography, and chest radiography. Bladder recurrence was confirmed through biopsy, urine cytology, or radiologic examination. Univariate and multivariate Cox regression analyzes were performed for statistical analysis of risk factors leading to radical cystectomy in patients undergoing NUx. Results: Lymphovascular invasion (LVI) (hazard ratio [HR], 4.728; 95% confidence interval [CI], 1.463–15.570; p=0.011), previous transurethral resection of bladder tumor history (HR, 3.825; 95% CI, 1.164–12.571; p=0.027), and intravesical recurrence (IVR) within 6 months (HR, 3.733; 95% CI, 1.091–12.778; p=0.036) in patients undergoing NUx are predictors of radical cystectomy implementation. In a multivariate analysis of patients without bladder cancer history, bladder recurrence was identified as a predictor of radical cystectomy implementation, if it occurred within 6 months of NUx (HR, 8.608; 95% CI, 1.545–47.976; p=0.014). Conclusions: LVI and IVR within 6 months and previous bladder cancer history are factors that can predict the need for radical cystectomy after NUx. Even in patients without bladder cancer history, early bladder recurrence within 6 months is a major predictor of radical cystectomy.
Utility of Urinalysis as a Follow-up Surveillance Tool in Nonmuscle Invasive Bladder Cancer
Minuk Park(박민욱),Bumjin Lim(임범진),Dalsan You(유달산),In Gab Jeong(정인갑),Cheryn Song(송채린),Bumsik Hong(홍범식),Choung-Soo Kim(김청수),Hanjong Ahn(안한종),Jun Hyuk Hong(홍준혁) 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.4
Purpose: To evaluate the association between microscopic hematuria (MH) detected by surveillance urinalysis and cancer recurrence in nonmuscle invasive bladder cancer (NMIBC) patients. Materials and Methods: A total of 1,082 NMIBC patients who underwent transurethral resection of bladder tumor (TURB) procedures at Asan Medical Center between January 2017 and December 2019 were included. We retrospectively reviewed the follow-up data for these cases including cystoscopy, urinalysis, and urine cytology. The association between urine testing and cancer recurrence was assessed by both univariable and multivariable logistic regression analysis. Results: The study patients had a median age of 68 years (interquartile range, 60–75 years) and comprised 898 men and 184 women. Among the 1,428 TURB procedures conducted in this series, 548 of the lesions (38.4%) were diagnosed as low-grade and 880 (61.6%) as high-grade cancers. A total of 3,309 follow-up cystoscopies were conducted during the study period and were divided into high-grade (HG) (2,011 cases) and low-grade (LG) (1,298 cases) groups according to the latest TURB pathology. MH was found to have a statistically significant association with NMIBC recurrence in both the LG (odds ratio [OR], 1.57; 95% confidence interval [CI], 1.107–2.223; p=0.011) and HG (OR, 1.90; 95% CI, 1.434–2.517; p<0.001) groups. Conclusions: Urinalysis during follow-up may provide important information on cancer recurrence in NMIBC patients.
자기결정성과 여행상품의 속성이 여행상품 선택과 고객만족에 미치는 영향에 관한 탐색적 연구
이동헌 ( Dongheon Lee ),임병훈 ( Byunghoon Lim ),손영석 ( Youngseok Son ),지범진 ( Bumjin Ji ) 한국고객만족경영학회 2016 고객만족경영연구 Vol.18 No.2
본 연구는 최근 변화하는 여행행태를 반영하여 자기결정성과 여행상품의 속성이 여행상품 선택에 미치는 영향을 파악하고, 소비자가 추구하는 자기결정성의 충족이 여행상품의 만족도에 미치는 영향력을 분석하려는 시도이다. 이를 위해 최근 2년 이내 해외여행 경험이 있는 소비자들을 대상으로 설문조사를 통하여 자료를 수집, 분석에 활용하였다. 실증적 분석 결과, 자기결정성의 차원은 Deci 와 Ryan(1985)의 연구와 동일하게 ``자율성``, ``유능성``, ``관계성``의 세 가지 요인으로 구성되는 것으로 나타났으며, 다항로짓분석을 적용하여 여행자의 상품선택행동을 모형화하여 분석한 결과, 전반적으로 여행상품 속성 중 여행지 안전, 볼거리, 여행비용, 일정의 유연성과 자기결정성 요인 중 유능성과 관계성이 유의한 영향을 미치는 것으로 나타났다. 개별여행을 선택하는 소비자들의 경우 자기결정성 요인들 중 자율성, 유능성, 관계성 모두가 유의하게 나타났으며, 여행지 안전, 여행비용, 숙박시설이 유의한 속성으로 나타났다. 자기결정성 수준에 따라 소비자들이 느끼는 만족도에 대한 분석 결과 선택한 여행상품의 자기결정성 수준이 여행자가 원하는 내용과 일치할수록 만족도가 커지는 것으로 파악되었다. The purpose of this study is to examine the effects of self-determination and attributes on the choice of travel products and the level of satisfaction. For the practical analysis of the importance of the concept of self-determination, the research model as in Figure 1 was formalated. Next, questionnaire was designed and distributed to travelers with foreign travel experience within recent 2 years. In total, valid data from 374 respondents were analyzed. The results showed that the dimension of self-determination was grouped into three factors, autonomy, competence, and relatedness. The result was similar to the self-determination theory of Deci and Ryan. The results from multinomial logit analysis showed that among the attributes of travel products security of travel destination, sight attraction, travelling expenses, and schedule flexibility were found to be significant influential factors. Among three factors of self-determination theory, competence and relatedness were found to be significant. The analysis about the different types of travel demonstrated that in the case of individual travel, all three dimensions of self-determination, autonomy, competence, and relatedness were found to be important. Further, travel destination security, travelling expenses, hotel facility, and local activity were turned out to be significant variables.
Se Young Choi(최세영),Ho Heon Kim(김호헌),Bumjin Lim(임범진),Jong Won Lee(이종원),Young Seok Kim(김영석),Jeong Kon Kim(김정곤),Jae Lyun Lee(이재련),Yong Mee Cho(조영미),Dalsan You(유달산),In Gab Jeong(정인갑),Cheryn Song(송채린),Jun 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.4
Purpose: To construct a urologic cancer database using a standardized, reproducible method, and to assess preliminary characteristics of this cohort. Materials and Methods: Patients with prostate, bladder, and kidney cancers who were enrolled with diagnostic codes in the electronic medical record (EMR) at Asan Medical Center from 2007–2016 were included. Research Electronic Data Capture (REDCap) was used to design the Asan Medical Center-Urologic Cancer Database (AMC-UCD). The process included developing a data dictionary, applying branching logic, mapping clinical data warehouse structures, alpha testing, clinical record summary testing, creating “standards of procedure,” importing data, and entering data. Descriptive statistics were used to identify rates of surgeries and numbers of patients. Results: Clinical variables (n=407) were selected to develop a data dictionary from REDCap. In total, 20,198 urologic cancer patients visited our institution from 2007–2016 (bladder cancer, 4,616; kidney cancer, 5,750; prostate cancer, 10,330). The overall numbers of patients and surgeries increased over time, with robotic surgeries rapidly growing over a decade. The most common treatment for urologic cancer was surgery, followed by chemotherapy and radiation therapy. Conclusions: Using a standardized method, the AMC-UCD fosters multidisciplinary research. This constructed database provides access to clinical statistics to effectively assist research. Preliminary data should be refined through EMR chart review. The successful organization of data from 2007–2016 provides a framework for future periods of investigation and prospective models.
Multifunctional Green Solvent for Efficient Perovskite Solar Cells
Jaemin Cho,Beomsoo Kim,Seokjoo Ryu,Alan Jiwan Yun,Bumjin Gil,Jiheon Lim,Jihyun Kim,Jinhyun Kim,Byungwoo Park 대한금속·재료학회 2023 ELECTRONIC MATERIALS LETTERS Vol.19 No.5
Organometal trihalide perovskite has recently been considered as one of the leading candidates to achieve highly effi cient perovskite solar cells (PSCs). However, current PSC procedures commonly rely on the large volume of highly toxic halogenated or highly fl ammable solvents which are not favorable for the large-scale commercialization of PSCs. Herein, we employ nontoxic and nonhalogenated salicylaldehyde from the buckwheat as a both nonpolar (antisolvent) and polar (posttreatmentdissolving) solvent for the multifunctional purpose. Salicylaldehyde has a semipolar characteristic due to the hydroxyl group (–OH) attached to the benzene ring, enabling it to utilize both polar and nonpolar solvents in the PSCs fabrications. As a result, the PSC using green solvent achieved a power conversion effi ciency (PCE) up to 20.23%. Encapsulated devices retained over 80% of their initial PCE, after ~ 750 h of constant 1-sun illumination, and after ~ 1100 h under 60 °C heat. Overall, this work demonstrates that salicylaldehyde can be an alternative solvent for green and effi cient fabrication in the PSC.