인체대장암에서의 Cyclin 유전자의 발현

백원기,서민호,서성일,문성희,박종욱,최병길,배옥석 대한대장항문학회 1996 Annals of Coloproctolgy Vol.12 No.2

원발성 위장관 악성 림프종의 임상적 고찰 : 치료 결과를 중심으로

원종호,백승호,홍대식,오도연,박희숙 순천향대학교 1994 논문집 Vol.17 No.4

저자들은 1984년 3월부터 1992년 12월까지 순천향 대학교 부속병원에서 원발성 위장관 악성 림프종으로 진단되었던 23명을 대상으로 다음과 같은 결론을 얻었다. 1. 대상 환자의 나이의 중앙치는 44(23-75)세로 남녀비가 2.8 : 1이었다. 2. 원발병소는 위 10예(43.5%), 소장 8예(34.8%) 및 회맹장 이행부위 5예(21.7%)였고, 병기 Ⅰ??기 8예(34.8%), Ⅱ??기 12예(52.2%), Ⅲ기 2예(8.7%), Ⅳ기 1예(4.3%)였다. 동반된 다른 장기는 주로 복부 임파절이었으며 폐 임파절 침범이 1예 있었고, 간을 침범한 경우가 1예, 위장과 소장에 병발한 경우가 1예 있었다. 조직학적 분류로는 중등도 19예(82.6%) 및 고도 4예(17.4%)였고 10예(43.5%)에서 B 증후가 있었다. 3. 치료를 시행한 20예중 Ⅰ??기 7예는 수술적 치료후 보조항암화학요법을 시행하였으며, Ⅱ??기 13예중 진단적 개복술후 완전절제가 확인된 3예는 보조항암화학요법을, 불완전절제로 확인된 7예는 관해유도 항암화학요법을 시행하였고, 3예는 항암화학요법만을 시행하였다. 4. 치료를 시행한 20예의 생존기간은 중앙치 43(4-100??개월이었으며, 3년 생존율 60.9%, 5년 생존율 40.6%였다. 5. Ⅰ??기 7예의 생존기간은 중앙치 42(11-100??개월이었으며, Ⅱ??, Ⅲ기 13예에서 치료에 대한 완전 관해가 9례(70%), 부분관해(15%), 무반응이 2례(15%)로 관해율은 85%였으며, 생존기간은 중앙치 44(4-52??개월이었다. 6. 완전관해자가 진행시까지의 관해지속기간은 중앙치 43(10-56??개월이었으며, 3년 무병생존율 79.1%, 5년 무병생존율 36.2%였다. Over a 8-year period(March 1984 through December 1992), 23 patients with primary gastrointestinal non-Hodgkin's lymphoma treated at Soonchunhyang University Hospital were analyzed with the following results; 1. The mean age of the patients was 43(23-75) years with male to female ratio of 2.8 : 1. 2. The primary sites of lymphoma were stomach in 10(43.5%), small intestine in 8(34.8%), and ileocecal area in 5(21.7%) and by modified Ann Arbor system, stage Ⅰ?? was 8(34.8%), stage Ⅱ?? was 12(52.2%), stage Ⅲ was 2(8.7%), and stage Ⅳ was 1(4.3%). Histologic classification by Working formulation revealed 19 cases(82.6%) of intermediate grade and 4 cases(17.4%) of high grade. B symptoms were observed in 10 cases(43.5%). 3. Treatments were performed in 20 cases as follows : In 7 cases with stage Ⅰ, complete surgical resection with systemic combined chemotherapy was performed. In 13 cases with stage ⅡE and Ⅲ, complete resection with systemic combined chemotherapy in 3 cases, incomplete resection with combined chemotherapy in 7 cases, and combined chemotherapy only in 3 cases. 4. Median survival duration of 20 treated patients was 43(4-100?? months and 3-year survival rate and 5-year survival rate were 60.9% and 40.6%, respectively. 5. Median survival duration of 7 cases with stage Ⅰ?? was 42 months(11-100??. In 13 cases with stage Ⅱ??, Ⅲ, response to treatment was complete remission in 9(70%), partial remission in 2(15%), and no response in 2(15%) resulting 85% of response rate and median survival duration was 44(4-52?? months. 6. Disease free survival rate of achieving a complete remission was 43(10-56?? months and 3-year disease-free survival rate and 5-year disease-free survival rate were 79.1% and 39.2%, respectively.

일부 조선업 근로자의 직업성 요통 발생실태 및 위험요인에 관한 연구

고상백,김형식,최홍렬,김지희,송인혁,박준한,박종구,장세진,차봉석 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1

목적 : 이 연구에서는 한 사업장의 동일한 코호트내에서 직업성 요통의 발생 및 발생원인에 대해 조사하고자 하였다. 방법 : 연구대상은 1995년 12월 현재 한 조선업체에 종사하는 근로자 중에서 1995년 12월 31일 까지 요통이 이미 발생한 근로자와 1995년 당시 검진 미수검자를 제외한 9,784명을 연구대상으로 하였다. 요통 발생군은 1996년부터 1998년까지 3년간 추적 관찰하여 요통으로 4일 이상 통원 또는 입원치료를 받은 근로자로 하였다. 발생률은 요통발생 당시 연도를 기준으로 하여 해당 연도의 4일 이상 신규치료를 받은 중등도 이상의 요통근로자를 분자로 하였고, 해당년도 사업장의 종사하는 근로자 총수(과거 요통자 제외)를 분모로 간주하였다. 요통 발생군은 외상성 요통과 직업관련성 요통으로 대별하였으며, 위험요인과 질병 발생간의 관련성을 보기 위한 Cox모형에서 그 위험도를 파악하고자 할 때에는 직업성 요통만을 환자군으로 선정하였다. 결과 및 결론 . 요통 발생률은 근로자 천명당 1998년 3.1명, 1997년 8.8명, 1996년 7.8명이었다. 요통점유율의 범위는 10.99∼25.66이었다. 연령별 요통 발생률은 30대, 40대에서 높은 발생률을 보였다. 진단명에 따른 발생률은 추간판 탈출증, 염좌, 척추골절, 척추분리증, 척추협착증 순이었다 직업성 요통 발생자들의 직업적 요인을 알아보기 위하여 요통 발생 당시 작업형태를 알아본 결과, 물건을 들다가 66명(35.3%)이 발생하여 가장 큰 빈도를 차지하였고, 물건을 옮기는 과정에서 19명(10.2%)이 발생하여 2위를 차지하였고, 넘어지거나(8.6%), 물건을 당기는 자세(8.0%), 값자기 일어서다(7.5%) 순으로 요통이 발생하였다. 직업성 요통에 영향을 주는 일반적 특성 및 직업적 특성에 판한 상대위험도 및 95% 신뢰구간를 구한 결과, 요통발생에 영향을 주는 유의한 변수로는 체질량 지수(비만도), 교대여부, 중량물 취급여부였다. Objectives : This study was conducted to estimate the incidence rate, and to identify the risk factors for the occupational low back pain among shipyard workers. Methods : The study subjects consisted of 9,784 workers who were employed in a ship-building industry (excluded workers who had a history of low pack pain before 1995 or did not take periodic health examination in 1995) . The cases were 220 people who experienced back pain from January 1, 1996 to December 31, 1998. To assess risk factors for occupational low back pain, Cox propotional hazard model was used. Results : During the recent three years from 1996 to 1998, the incidence rate per 1,000 persons was 7.8 in 1996, 8.8 in 1997, and 3.1 in 1998. The main causes of work-related low back pawn were sprain, strain and disc herniation. Lifting was the most common cause of back pain (35.3%) , and carrying (10.2%) and pulling (8.0%) were followed. In Cox proportional harzard model, independent risk factors for back pain were body mass index(R.R. ; 1.54, 95% C.1. : 1.06-2.25), shift work(R.R. ; 1.65, 95% C.1. : 1.19-2.28), and lifting heavy material(R. R., 3.95, 95% C.1. : 2.29-6.82). Conclusions . This study suggests that the risk factors of back pawn In shipyard work-ers were body mass index, shift work and lifting.

Sludge를 이용한 자기 연마재 개발

김희남,윤여권,김상백,최희성,안효종 한국안전학회 2004 한국안전학회지 Vol.19 No.2

The magnetic polishing is the usefiil method to finish using magnetic power of magnet. This method is one of precision polishing techniques and has an aim of the clean technology using for the pure of gas and inside of the clean pipe for transportation. The magnetic abrasive polishing method is not so common for machine that it is not spreaded widely. There are rarely researcher in this field because of non-effectiveness of magnetic abrasive. Therefore, in this paper deals with development of the magnetic abrasive using sludge. In this development, abrasive grain WA and GC used to resin bond fabricated low temperature. And magnetic material was fabricated from the sludge which were crused into 200 mesh and average diameter 01.2mm ball type. The XRD analysis result show that only WA and GC abrasive and sludge crystal peaks detected which explains resin bond was not any more chemical reaction. From SEM analysis it is found that WA and GC abrasive and sludge were strong bonding with each other by bond.

재래종 콩 유전자원의 주요 형태적 특성과 변이

윤문섭,백형진,이정란,김행훈,조양희,안종웅,김창영 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.4

본 실험은 한국, 중국 및 일본 재래종 콩 유전자 자원의 주요형질 변이를 조사하고 이들 자원간의 지리적 유연관계를 비교하고자 수행하였으며, 그 결과를 요약하면 다음과 같다. 1. 경장은 한국(66㎝)이나 일본자원(54.9㎝)보다 중국자원(71㎝)에서 더 컸으며, 또한 변이도 중국자원에서 가장 큰 것으로 나타났다. 2. 개화일수 및 생육일수는 한국자원(65.5일, 151.4일)이 가장 길었으며 중국(57일, 120일)과 일본자원(59.9일, 122.4일)은 같은 경향을 나타냈다. 또한 한국과 중국자원은 지역에 따른 차이를 나타냈으나 일본자원에서는 확인할 수 없었다. 3. 백립중은 한국(18.8g), 일본(17.2g) 및 중국(14.7g) 순으로 무거웠다. 특히 한국자원은 9~11g과 23~25g에서 정점을 나타냈고, 변이폭도 가장 컸다. 반면 일본과 중국자원은 13~17g사이에서 정점을 나타냈다. 4. 협수는 중국(46.9개)이나 일본자원(36.5개)보다 한국자원(75.5개)에서 가장 많았으며, 변이폭도 한국자원에서 가장 컸다. 내도복성은 일본자원에서 가장 강하였다. 5. 정준판별분석결과 can 1을 경계로 하여 오른쪽 상하에 한국재래종이 주로 분포하였고 왼쪽에는 중국과 일본 재래종이 주로 분포하여 각 나라별로 고유한 영역을 가지고 분리되었다. 전체적 경향이 중국과 일본자원이 한국자원보다 가까운 경향을 나타냈다. This experiment was carried out to compare the characters of 944 Korean soybean landraces, 716 Chinese, and 170 Japanese soybean landraces introduced from USDA soybean germplasm collection. Cannonical discriminant and cluster analyses were conducted by their origins. The population from China was taller in plant height than those from Korea and Japan, also its variation was largest in Chinese population. The population from Korea was langer than those from China and Japan in terms of days to flowering and maturity. Also, Korean and Chinese accessions appeared the difference of those traits according to latitude. One hundred seeds weight was in the order of Korean(18.8g), Japanese(17.2g) and Chinese populations(14.7g), especially Korean population was distinguished into two groups; the group including accessions between 10 and 15g, and the other group including accessions between 20 and 25g. However, others showed the peak in range of 13~17g. The number of pod per plant was more in Korean accession(75.5) with the largest variation than Chinese(46.9) and Japanese accession(36.5). The distribution of Korean, Chinese and Japanese accessions reflected the origin of accessions analyzed by cannonical discriminant analysis. The relationship between their geographical origins showed the population of China and Japan are losely related.

구개부에 발생한 다형선종의 처치

하주원,백승,송종운,박충열,이용욱,박홍주,오희균,유선열,김옥준 大韓顎顔面成形再建外科學會 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.6

Pleomorphic adenoma of the palate is the most common of all intraoral salivary tumors. It can occur at any age but it presents most commonly in the 40∼60 age group, and there is no significant sex preponderance. It grows slowly and is usually painless, firm, well-circumscribed nodule. Because of high rate of recurrence, extra-capsular excision including the overlying mucosa and margin of normal tissue is recommended. We report 10 cases of palatal pelomorphic adenoma which have been successfully treated by extra-capsular excision. The surgical defects smaller than 3㎝ in diameter were covered with palatal acrylic splint for the secondary healing. The larger defects were repaired using palatal island flap in 3 cases, rotation flap and buccal fat graft in each 1 case. No patient showed any recurrence or malignant change during the mean follow-up period of 4 years and 9 months. These repair methods seem to be simple, reliable and uncomplicated procedures in the palatal surgical defects.

Risk factors for locoregional recurrence in patients with pathologic T3N0 rectal cancer with negative resection margin treated by surgery alone

Jong Yun Baek,Jeong Il Yu,Hee Chul Park,Doo Ho Choi,Gyu Sang Yoo,Won Kyung Cho,Woo-Yong Lee,Seong Hyeon Yun,Yong Beom Cho,Yoon Ah Park,Hee Cheol Kim 대한방사선종양학회 2019 Radiation Oncology Journal Vol.37 No.2

Purpose: This study aimed to identify prognostic factors for locoregional recurrence (LRR) in pT3N0 rectal cancer patients who were treated with surgery alone and had negative resection margin including circumferential resection margin (CRM) for optimal indication of adjuvant radiotherapy. Materials and Methods: We reviewed patients with pT3N0 rectal cancer who were treated via upfront surgery and had no other adjuvant treatment from January 2003 to December 2012. In total, 122 patients who had negative resection margin including negative CRM were included in the analysis. Results: The median follow-up period after surgery was 60 months (range, 3 to 161 months). During this time, 6 patients (4.9%) experienced LRR at the anastomotic site (4 patients), and regional lymphatic area (2 patients). The estimated 5-year rates of overall survival, recurrence-free survival, and LRR-free survival were 96.7%, 84.6%, and 94.0%, respectively. Multivariate analysis showed that level of tumor ≤5 cm was a significant prognostic factor for LRR-free survival (LRRFS) (p = 0.04; hazard ratio = 7.08; 95% confidence interval, 1.06–47.30). Patients with level of tumor ≤5 cm had an estimated 5-year LRRFS of 66.8%, which was much higher than 2.3% in patients with level of tumor >5 cm. There was no significant factor for recurrence-free survival or overall survival. Conclusion: In T3N0 rectal cancer, adjuvant chemoradiotherapy should be recommended in patients with level of tumor ≤5 cm for better local control. However, in patients with pT3N0 disease, negative resection margin, and level of tumor >5 cm, adjuvant chemoradiotherapy should be carefully suggested.

Risk factors for locoregional recurrence in patients with pathologic T3N0 rectal cancer with negative resection margin treated by surgery alone

Baek, Jong Yun,Yu, Jeong Il,Park, Hee Chul,Choi, Doo Ho,Yoo, Gyu Sang,Cho, Won Kyung,Lee, Woo-Yong,Yun, Seong Hyeon,Cho, Yong Beom,Park, Yoon Ah,Kim, Hee Cheol The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.2

Purpose: This study aimed to identify prognostic factors for locoregional recurrence (LRR) in pT3N0 rectal cancer patients who were treated with surgery alone and had negative resection margin including circumferential resection margin (CRM) for optimal indication of adjuvant radiotherapy. Materials and Methods: We reviewed patients with pT3N0 rectal cancer who were treated via upfront surgery and had no other adjuvant treatment from January 2003 to December 2012. In total, 122 patients who had negative resection margin including negative CRM were included in the analysis. Results: The median follow-up period after surgery was 60 months (range, 3 to 161 months). During this time, 6 patients (4.9%) experienced LRR at the anastomotic site (4 patients), and regional lymphatic area (2 patients). The estimated 5-year rates of overall survival, recurrence-free survival, and LRR-free survival were 96.7%, 84.6%, and 94.0%, respectively. Multivariate analysis showed that level of tumor ≤5 cm was a significant prognostic factor for LRR-free survival (LRRFS) (p = 0.04; hazard ratio = 7.08; 95% confidence interval, 1.06-47.30). Patients with level of tumor ≤5 cm had an estimated 5-year LRRFS of 66.8%, which was much higher than 2.3% in patients with level of tumor >5 cm. There was no significant factor for recurrence-free survival or overall survival. Conclusion: In T3N0 rectal cancer, adjuvant chemoradiotherapy should be recommended in patients with level of tumor ≤5 cm for better local control. However, in patients with pT3N0 disease, negative resection margin, and level of tumor >5 cm, adjuvant chemoradiotherapy should be carefully suggested.

The Effects of Traditional Korean Restaurant's Well-Bing Attribute Selection on Customers' Re-Visitation and Word-of-Mouth Intention

Hee Jong Yang,Hang Sun Baek,Chan Hee Kim,Chung Sub Shin 한국유통과학회 2016 KODISA ICBE (International Conference on Business Vol.2016 No.-

This study analyzes what effects on restaurants' well-being attribute selection have on word-of-mouth intention. Based on the result, this study aims to provide basic data for establishing Korean restaurant's service strategy and marketing strategy. The researchers surveyed 350 customers who visited a Korean restaurant located in Kangbook, Seoul. We encoded gathered data and analyzed them using SPSS 17.0 statistics package program. Following are the analyzed results. First, under hypothesis 1 - Korean restaurant's well-being attribute selection will have a positive influence on re-visitation intention - it shows that sufficiency, healthiness, and steadiness have similar influence on re-visitation intention. Second, under hypothesis 2 - Korean restaurant's well-being attribute selection will have a positive influence on word-of-mouth intention - it shows that sufficiency, healthiness, environment, and steadiness have similar influence on word-of-mouth intention. Third, under hypothesis 3 - Korean restaurant's re-visitation intention will have a positive influence on word-of-mouth intention - it is considered that eliciting customer's re-visitation intention also has influence on word-of-mouth intention. It will be necessary to consult how to derive customer's re-visitation intention or word-of-mouth intention by considering factors which customers of traditional Korean restaurant value.

FDG-PET in Mediastinal Nodal Staging of Non-small Cell Lung Cancer: Correlation of False Results with Histopathologic Finding

Hee Jong Baek,Jin-Haeng Chung,Jong-Ho Park,Jae Ill Zo,Gi Jeong Cheon,Chang-Woon Choi,Sang-Moo Lim,Soo Yong Choi,Jong Myeon Hong,Jang Soo Hong 대한암학회 2003 Cancer Research and Treatment Vol.35 No.3