Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

성상세포종의 MIB-1, AgNORs 및 PCNA 발현에 대한 비교연구

최양문,김태영,김종문,윤기중,문형배 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.4

슬관절 등속성 운동시 근골격 모델의 검증:실험 및 모의실험 연구 : 실험 및 모의실험 연구 An Experimental and Simulatio study

배태수,강성재,최경주,김신기,유재욱,진미령,문무성 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

등가 Half-bridge모델 공진형 고주파 인버터

배영호,이현우,홍성태,서기영,차영문,권순걸 慶南大學校 附設 工業技術硏究所 1992 硏究論文集 Vol.10 No.-

이 논문은 MOSFET로 구성된 등가 Half-bridge형 고주파공진형 인버어터에 대해 기술하고 있다. 시분할 방식에 의한 게이트회로를 구성하여 구동함으로써 출력단에는 두개의 인버어터에서 동작되는 순시위상이 합성되어 있어 나타나므로 부하단 출력주파수는 소자의 수위칭주파수에 대해 두배가 되고 수위칭 손실이 경감되어 소자의 평균전류가 증가한다. This paper proposes a high frequency resonant inverter consisting of equivalent half bridge model using MOSFET. In this paper time-sharing control method is applied. as a result the output frequency is two times as high as switching frequency of device and average current of device is increased because of decreasing switching loss.

Hydroxybiphenyl 유도체의 항균작용(Ⅲ) : 충치균 Streptococcus mutans에 대한 p-Phenylphenol 유도체의 항균작용 The Antibacterial Activities of p-Phenylphenol Derivatives against a Cariogenic Bacterium Streptococcus mutans

배기환,서원준,박종태 충남대학교 약학대학 의약품개발연구소 1991 藥學論文集 Vol.7 No.-

For the purpose of developing of anticariogenic agents, p-phenylphenol derivatives were synthesized and determined their antibacterial activities against a cariogenic bacterium, Streptococcus mutans. Among synthetic compounds, 2-nitro-6-bromo-p-phenylphenol showed as potent antibacterial activity as magnolol and honokiol.

하드 포인트 변경에 따른 조종안정성 평가

배태한,장석동,송철기 慶尙大學校 經營行政大學院 2004 工學硏究院論文集 Vol.20 No.-

Vehicle stability is an important subject in vehicle design and control, because vehicle stability is closely dependent upon its dynamic performance. The modeling and its analysis are performed by using ADAMS in the present paper. The camber angle and the toe angle are analyzed due to the hard point movement in the static simulation. The side slip angle and the yaw rate are analyzed due to the hard point movement in the driving simulation such as the steady state cornering and the double lane change.

혈관조영색전술을 이용한 비조절성 후비강부 출현의 처치 : 증례 보고

남기영,권대근,김종배 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.4

The posterior nasal bleeding sometimes develope a life threatening situation because of its limited access and the profuse vascular network of the bleeding area. There are various methods of hemostasis including packing, cautery, and arterial ligation those vary in effectiveness. But sometimes patients cannot tolerate these methods or show rebleeding sign. So, if all of these methods are not successful, we should consider the further treatment. The selective angiographic embolization has various advantages such as rapidness, repetition, good visualization, and being performed under local anesthesia, therefore it can provide useful way in patients with massive, intractable posterior nasal bleeding. We report a case of angiographic embolization for intractable posterior nasal bleeding patient and review the effectiveness of the this treatment.

후박 및 은행엽 추출물을 함유한 치약의 임상 및 미생물학적 효과에 관한 연구

김태일,염혜리,류인철,배기환,정종평 충남대학교 약학대학 의약품개발연구소 1996 藥學論文集 Vol.12 No.-

Previous studies have shown that Magnoliae cortex and Ginkgo biloba extracts were showed on the antimicrobial and anti-inflammatory action, in vitro. The purpose of this study was to evaluate on the effect of antimicrobial and anti-inflammatory activity of Magnoliae cortex and Ginkgo biloba extracts containing dentifrice in gingivitis. 70 subjects with gingivitis were divided into an experimental group which performed normal oral hygiene procedure with Magnoliae cortex and Ginkgo biloba extracts containing dentifrice and a control group which also performed normal oral hygiene procedure with the same dentifrice without the natural extracts and completed a double-blind, cross-over study. At baseline and 3 weeks, subjects were assayed for clinical study by plaque index, gingival index, pocket depth, GCF rate, and microbiological study by subgingival dental plaque bacterial morphotypes by phase contrast microscopy, total anaerobes, total aerobes, Black pigmented bacteroides, A-actionomycetemcomitans, A.viscosus, C.rectus, S.sanguis, P.gingivalis, P.intermedia by bacterial culture and immunofluorescence microscopy. After 3 weeks using their respective dentifrices, reductions in the clinical indices of subjects were similar between the experimental dentifrice group and a control dentifrice group except for statistically significant much reductions in PI, GI, and GCF rate in the experimental dentifrice group as compared to control dentifrice group. Also statistically significant reductions in the motile rods and Spirochetes were found in both experimental group to compare with control group, however statistically much reduction in total anaerobes, Black pigmented bacteroides, and P.gingivalis, P.intermedia were found in the experimental dentifrice group as compared to control dentifrice group. This results indicates that Magnoliae cortex and Ginkgo biloba extracts containing dentifrice might be useful for elimination of gingival inflammation.

燐酸質 强化堆肥의 分肥施用이 水稻의 收量 및 收量構成要素에 미치는 影響에 관한 硏究...(基1) : Correlation of residual humus in soil and some factors related with yields. 旣存 土壤腐植 및 收量 構成要因調査

金正基,裵泰雄 東亞大學校 1967 東亞論叢 Vol.4 No.-

"燐酸質 强化堆肥의 分肥施用이 水稻의 燐酸利用度에 미치는 影響에 關한 硏究" -(基1) (旣存土壤腐植 및 收量 構成要因 調査) 1. 基礎調査 ① 處理區의 酸性度는 實驗後에 大體로 0.5程度 pH 값이 中性에 가까워졌다.(5.5→6.0) ② 試驗前後의 生性은 處理內容에 따라 變化가 없었다. ③ 試驗前의 土壤中에 旣存하는 腐植含量을 檢定한 값은 2.0~2.3% 範圍였다. ④ 10穗當 粒 重量(乾物重)으로 본 P₂O??質 50% 增肥 및 强化 堆肥의 基追肥 處理 效果는 Chai(Z) 檢定에서 有意性이 없는 結論이었다.(Z²=0.137<3.84=P0.05) 그런데, 對比區와의 比率은 18% 程度의 間接 收量의 增收가 認定되었다. 2. 旣存 有機物 含量과 作況(結實期) ① 有機物 含量과 株當穗數와는 γ=0.67*>0.66=γ0.05)라는 正의 相關이 認定되었으며 Y=0.99X +1.36이라는 回歸가 成立되었다. ② 有機物 含量과 收量, 草長, 穗粒數와는 有意性있는 結論이 認定되지 않았다. (相關關係調査에서) 3. 結實形成要因(作況) 相互關係 ① 稈長과 穗粒重間에는 B區에서 負의 相關係數(γ= -0.438*>0.361=γ0.05, df. =28)가 有意性을 보였으며, 回歸도 또한 Y=1.35-0.037X 였다. ② 粒數와 粒重間에는 A, B, C區 共히 γ=0.581**, γ=0.439**, γ=0.901라는 1% 水準의 高度의 有意性이 認定되었으며, 回歸式도 또한 Y=0.016X + 0.465 (A區) Y=0.0152X + 0.452 (B區) Y=0.0274X + 0.216 (C區) 과 같이 表示되었다. ③ 稈長과 粒數間에는 相關關係가 負로 나타났으며 有意性이 없었다. ④ 株當穗當數와 草長間에는 B區에서 γ=0.641라는 1% 水準의 高度의 有意性 있는 正 相關關係가 認定되었고, A, C區에서는 認定되지 않았다. ⑤ 草長과 穗粒數間에는 A, B區에서 各各 γ=0.9139***, γ=0.693**라는 1% 水準의 有意的인 相關이 認定되었으며 C區에도 γ=0.464<0.514=γ0.05라는 5% 水準에 가까운 相關關係가 認定되었다. 또한 Y=1.75X +0.51 (A區)와 Y=2.49X +0.967 (B區)의 回歸도 認定되었다. 以上에서 草長과 穗粒間에는 有意性있는 正相關이, 그리고 稈長과 粒數間에는 有意性 없는 負의 相關이 認定되었다. ⑥ 草長과 收量間에는 γ=0.69*>0.66(=γ0.05)라는 正相關이, 그리고 Y=0.0293X + 0.602라는 回歸가 認定되었다. 以上에서 草長과 收量間에 有意性있는 正相關이, 그러나 稈長과 穗粒重(收量)間에는 有意性있는 負相關이 認定되는 것이다. ⑦ 各 處理間는 株當穗當數의 調査成績만이 F(처리)=4.52*>3.84(F(0.05))이라는 有意性을 보였으며, (L.S.D(0.05)=5.53) 10穗粒 重量(F=1.19<3.84)과, 草長調査(F=1.07<3.84)그리고 穗粒數(F=2.93<3.84) 등은 統計學的인 有意性있는 結論이 못 되었다. 1.Fundamental Survey ① The pH on treated plots have a tendency to neutralize the value of approximately 5.5 to 6.0. ② In Oil texture of each plot before and after the experiments there was not a big change according to each treatment. ③ Soil humans contents identified before the experimental treatments, have the range of about 2.0~2.3 percentage. ④ Treating efficiency of the enriched manure multiplied by 50% of superphosphate and applied partially was showed statistically significant conclusion (X²=0.137<384=p, 0.05), but 18% of increased yield in grain were convinced as compared with the control. 2. Residual soil humus and rice status. ① Soil humus contents and head numbers by stump showed positive correlation as (γ=0.67*>0.66=γ0.05), and Y =0.95x + 1.36, the linear regression above. ② Correlation coefficients betwen soil humus(residual) and yield, total length, grain numbers per ear were insignificant. 3. Relation of some factors affected with yields. ① Linear regression and correlation coefficient (negative) between culm-length and grain weight per ear indicated significant effect showing (γ= -0.438*>0.361=γ0.05, df. =28), and Y=1.35-0.037X. ② Between grain numbers and grain weight in all plots (A, B, C), correlation coefficients showed significance of high degree at 1% level indicating γ=0.581**, γ=0.439**, γ=0.901** respectively, and Y=0.016X + 0.465······at plot A Y=0.0152X + 0.452······at plot B Y=0.0274X + 0.216 ······at plotC the above regression equation were approved. ③ No corelation coeficient between culm-length and grain number was approved statistically significant. ④ Between ear numbers and total-length, only in plotB, they showed highly significant correlation coefficient. ( γ=0.641**) ⑤ In plots A, B; total length and grain numbers per ear indicated highly significant correlation coefficient showing γ=0.9139**, and γ=0.693** respectively, and also showed regression equation like below Y=1.75X + 0.51······ A plot Y=2.49X + 0.967······ B plot The following were approved by this; positive correlation coefficient between total length and grain numbers showed significant, and negative correlation coefficient (insignificant) between culum-length and grain numbers. ⑥ Linear regression and correlation coefficient between total length and yields indicated positive significance showing γ=0.69*>0.66(=γ0.05)and Y=0.0293X + 0.602. The following were approved by this; positive correlation coefficnent were significant between total length and yields and negative correlation coeficient were significant between culm-length and yields. ⑦ In each treatment, only the ear-number per stump, respectively showed statistically significant, (F(t) = 4.52*>3.84 ( = F0.05), (L, S, D) = 5.53), and grain weight per 10 ears (F=1.19<3.84), total length(F= 1.07<3.84), grain number per ear (F = 2.93<3.84) were showed insignificant respectively.

일부 도시지역 성인들의 혈중지질치의 참고치 및 저콜레스테롤혈증에 미치는 요인 분석

유기하,이동배,이태용,조영채,김수영 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

Data from 3.982 adults participating in a health examination in a university hospital were analysed to determine the reference values of hyperlipidemia and hypolipidemia, and those were compared with American data. Also health related behaviors affecting hypocholesterolemia were investigated. 29.3% of the males diseased subjects, and as were 25.6% of the females in their twenties, 69.5% of the males in their 60s and 78.6% of the females in their 50s. The rate of diseased subjects tended increase with increasing age. The rates of the diseased were 60.1% for males and 55.2% for females. Among cardiovascular risk factors, the proportion of hyperlipidemia was 46.6%, fat liver 42.2%, hypertension 21.8%, glucose intolerance 13.7%, abnormal EKG 11. 0%, obesity 2.9% and anemia 1.7% for male subjects and hyperlipidemia was 31.2%, fat liver 29. 5%, anemia 27.5%, hypertension 21.1%, abnormal EKG 15.7%, obesity 7.3% for females in that order. The rates of cardiovascular risk factors were higher in males than in females except for anemia, abnormal EKG and obesity. The total cholesterol levels of 95 percentile for males and females were 227.0 mgldl, 226.0 mg/dl and the 5 percentile levels for males and females were 134.0 rag/dl, 131.0 mgldl, respectively. The LDL cholesterol level of 95 percentile for males and females were 150.0 mg/dl, 147.0 mgldl, and the 5 percentile were 53.0 mgldl, 51.0 mg/dl, respectively. The HDL cholesterol 95 percentile levels for males and females were 82.0 mg/dl, 83. 0 mg/dl, and those of 5 percentile were 36.0 mg/dl and 39.0 mg/dl, respectively. These data show that the mean levels of total cholesterol, triglyceride, LDL cholesterol were related to increased age in both sexes, and were slightly higher in the females than in the males over all ages, but those of HDL cholesterol decreased. The high cholesterol level group was associated with age, the amount of alcohol consumption, smoking and body mass index. But that was not associated with meat intake and regular exercise. No significant difference were found among the rates of all diseases except for diseases and anemia up to 160 mg/dl of cholesterol level in both sexes. Sex, regular exercise and glucose intolerance were revealed as influencing factors in the low serum cholesterol levels, but disease and abnormal EKG had a lowing effect for the low cholesterol risks. In conclusion, the reference values of Korean serum lipids were 5-25 mg/dl lower than Americans. The cut-off value to diagnosis hypolipidemia for the Korean is recommended as below 140 mg/dl of serum total cholesterol. The hyperlipidemia cut-off value should above 220 mg/dl of serum total cholesterol.