Nonlinear thermal vibration of pre/post-buckled two-dimensional FGM tapered microbeams based on a higher order shear deformation theory

Asmaa A. Hendi,Mohamed A Eltaher,Salwa A Mohamed,Mohamed A. Attia,A.W. Abdalla 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.41 No.6

The size-dependent nonlinear thermomechanical vibration analysis of pre- and post-buckled tapered two-directional functionally graded (2D-FG) microbeams is presented in this study. In the context of the modified couple stress theory, the formulations are derived based on the parabolic shear deformation beam theory and von Karman nonlinear strains. Different thermomechanical material properties are assumed to be temperature-dependent and smoothly vary in both length and thickness directions using the power law and the physical neutral axis concept is employed. The nonlinear governing equations are derived using the Hamilton principle and the resulting variable coefficient equations of motion are solved using the differential quadrature method (DQM) and iterative Newton’s method for clamped-clamped and simply supported boundary conditions. Comparison studies are presented to validate the derived model and solution procedure. The impacts of induced thermal moments, temperature power index, two gradient indices, nonuniform cross-section, and microstructure length scale parameter on the frequency-temperature configurations are explored for both clamped and simply supported microbeams.

Development of 1D/3D Perovskite Heterostructure for Highly Efficient, Stable Perovskite Solar Cells

Asmaa Dahyshaban Mohamed,Hock Beng Lee,강재욱 한국고분자학회 2023 한국고분자학회 학술대회 연구논문 초록집 Vol.48 No.1

Small dose of naloxone as an adjuvant to bupivacaine in intrapleural infiltration after thoracotomy surgery: a prospective, controlled study

Asmaa Fawzy Amer,Amany Faheem Omara 대한통증학회 2019 The Korean Journal of Pain Vol.32 No.2

Background: Severe pain always develops after thoracotomy; intrapleural regional analgesia is used as a simple, safe technique to control it. This study was performed to evaluate whether a small dose of naloxone with local anesthetics prolongs sensory blockade.Methods: A prospective, randomized double-blinded controlled study was conducted on 60 patients of American Society of Anesthesiologists statuses I and II, aged 18 to 60 years, scheduled for unilateral thoracotomy surgery. After surgery, patients were randomly divided into two groups: through the intrapleural catheter, group B received 30 ml of 0.5% bupivacaine, while group N received 30 ml of 0.5% bupivacaine with 100 ng of naloxone. Postoperative pain was assessed using the visual analog pain scale (VAS). Time for the first request for rescue analgesia, total amount consumed, and incidence of postoperative complications were also recorded.Results: The VAS score significantly decreased in group N, at 6 h and 8 h after operation (P < 0.001 for both). At 12 h after injection, the VAS score increased significantly in group N (P < 0.001). The time for the first request of rescue analgesia was significantly longer in group N compared to group B (P < 0.001). The total amount of morphine consumed was significantly lower in group N than in the bupivacaine group (P < 0.001).Conclusions: Addition of a small dose of naloxone to bupivacaine in intrapleural regional analgesia significantly prolonged pain relief after thoracotomy and delayed the first request for rescue analgesia, without significant adverse effects.

Immunohistochemistry of Janus Kinase 1 (JAK1) Expression in Vitiligo

Asmaa Gaber Abdou,Alaa Maraee,Hossam Yassien,Mona Sarhan 대한병리학회 2018 Journal of Pathology and Translational Medicine Vol.52 No.6

Background: Vitiligo is a chronic autoimmune disease in which the destruction of melanocytes causes white spots on the affected skin. Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK–signal transducer and activator of transcription pathway. The aim of the present study is to explore the possible role of JAK1 in the pathogenesis of vitiligo using immunohistochemical methods. Methods: The current study was conducted in a sample of 39 patients who presented with vitiligo and 22 healthy individuals who were age and sex matched as a control group. We used immunohistochemistry to evaluate JAK1 status (intensity and distribution) and assess the percentage of residual melanocytes using human melanoma black 45 (HMB45). Results: Intense and diffuse JAK1 expression was significantly more likely to indicate vitiliginous skin compared to normal skin (p < .001). Strong and diffuse JAK1 expression was associated with short disease duration, female sex, and lower percentage of melanocytes (detected by HMB45) (p < .05). Conclusions: JAK1 may be involved in the pathogenesis of vitiligo, as indicated by intense and diffuse expression compared to control and association with lower percentage of melanocytes detected by HMB45 immunostaining.

Variable Range Hopping in a Dilute GaAs/AlGaAs Hole System

Asmaa Chakhmane,Hassan El Idrissi,Abdelhamid El Kaaouachi,Mohamed Errai,Abdellatif El Oujdi,Adil Echchelh 한국물리학회 2019 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.75 No.5

In this work, we conducted an investigation concerning low-temperature electrical transport phenomena in a two-dimensional (2D) GaAs hole gas. The different carrier densities of the sample locate them on the insulating side of the metal-insulator transition (MIT). Two theoretical models of variable range hopping (VRH) conduction according to Mott (Mott VRH region) and according to Efros-Shklovskii (ES VRH region) are used in the modeling of the experimental measurements obtained by Qiuet \textit{et al.} [Phys. Rev. Lett. \textbf{108}, 106404 (2012)].

The impact of dietary linseed oil and pomegranate peel extract on broiler growth, carcass traits, serum lipid profile, and meat fatty acid, phenol, and flavonoid contents

Asmaa TY Kishawy,Shimaa A Amer,Mohamed E. Abd El-Hack,MOHAMEDISLAM MOHAMED SAAD ELDIN,Ayman A. Swelum 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.8

Objective: The current study aimed to replace soybean oil in broiler diets with linseed oil, which is rich in omega-3 fatty acid supplemented with pomegranate peel extract (PPE) and measured its effect on broiler performance, carcass traits, lipid profile, as well as fatty acids composition, phenols and flavonoids content of broiler muscles and immunity of broiler chicks. Methods: A total of 300 1-day-old Cobb chicks were randomly allotted into six experimental groups, T1 fed on basal diet with soybean oil without any additives, T2 fed on basal diet with soybean oil with addition of 0.5 g/kg diet PPE, T3 fed on fed on basal diet with soybean oil with addition of 1 g/kg diet PPE, T4 fed on basal diet with linseed oil without any additives, T5 fed on basal diet with linseed oil with addition of 0.5 g/kg diet PPE and T6 fed on basal diet with linseed oil with addition of 1 g/kg diet PPE. The PPE supplementation with 0.05% improved final body weight with either soybean oil ration or linseed oil ration. Results: The PPE improved carcass dressing percentage in comparison with the control groups. Body fat levels decreased with increasing PPE levels, especially with a linseed oil diet. Replacing soybean oil with linseed oil decreased the total cholesterol and triacylglycerol levels in broiler serum. The PPE supplementation decreased serum total cholesterol levels and increased high-density lipoprotein cholesterol levels. The content of the breast muscle alpha linolenic acid improved after replacement of soybean oil with linseed oil in broiler diets. PPE supplementation increased the phenol and flavonoid content in broiler meat and increased lysozyme activity. Conclusion: Replacing soybean oil with linseed oil in broiler diets with the addition of PPE enriched muscle meat with omega-3 fatty acids and antioxidants and improved broiler immunity and their serum lipid profile.

New Optimization Model for Multi-Period Multi-Product Production Planning System with Uncertainty

Asmaa A. Mahmoud,Mohamed F. Aly,Ahmed M. Mohib,Islam H. Afefy 대한산업공학회 2019 Industrial Engineeering & Management Systems Vol.18 No.4

The focus of this study is to develop a multi-period multi-product (MPMP) production planning system with uncertainty, and products demand (seasonal demand) uncertainty. Mainly, the problem aims reach the production levels ofeach product according to the uncertain demand for various periods, which depend on constraints of capacity, inventory, and resources. An analytical model proposed for this problem that can be categorized into two classes: non-linearand stochastic. The objective is to minimize the summation of variable production costs. As uncertain demand is adynamic stochastic data process in the planning horizon, it is considered as a tree model. Each stage in the demandtree model is related to a cluster of a period time. Hence, depending on the tree model for the fluctuation demand;Two-Stage Stochastic Programming (TSP) model is presented as an alternative for all demand scenarios. In some ofthe reviewed articles validation of the analytical model were missing, while other studies were missing either manufacturing set up costs or assumptions of seasonal demand. Therefore, this study proposes TSP model using SamplingAverage Approximation method (SAA) that is suitable for a production planning system in any manufacturing environment considering seasonal demand using optimization program (Lingo 16) to solve the mathematical model. Further, investigation of seasonal demand is performed using the multiplicative seasonal method, and the model validation was checked using Mathworks Matlab R2015a (64-Bit) considering manufacturing set up costs. Finally, somerecommendations for future research are suggested.

Impacts of Selection for Spike Length on Heat Stress Tolerance in Bread Wheat (Triticum aestivum L.)

Asmaa M. Mohamed,Mohamed K. Omara,Mahmoud A. El-Rawy,Mohamed I. Hassan 한국육종학회 2019 Plant Breeding and Biotechnology Vol.7 No.2

Two consecutive cycles of selection were imposed on five F2 populations of bread wheat. The first cycle was a divergent selection for spike length conducted in favorable environment (optimal sowing date) and the response was measured under favorable and heat stress conditions of a late sowing date. Positive responses to selection for longer spikes were obtained under favorable (13.43%) heat stress (8.66%) conditions, whereas the responses for shorter spikes were 2.24 and 5.02% in the two environments, respectively. The realized heritability of spike length was greater under favorable conditions (0.25-0.56) than under heat stress (0.18- 0.41). Concurrent positive responses to selection for longer spikes were obtained in grain yield per spike under favorable (25.35%) and heat stress (13.65%) environments. Selection for greater number of grains per spike imposed on F3 plants selected for spike length under heat stress resulted in significant responses (14.65%). Selection for greater number of grains per spike resulted in correlated responses in grain yield per spike (17.64%). The concurrent positive responses produced in spike length in F4 with selection for number of grains per spike (averaged 9.20%) was almost equal to that produced by the direct selection in F3 (8.66%), indicating that selection advance effected in F3 has been maintained in F4. High F4/F3 regression was obtained for spike length under heat stress (b = 0.85 ± 0.07), indicating high heritability. In conclusion, phenotypic selection for longer spikes under heat stress followed by a cycle of selection for number of grains per spike was capable of improving heat tolerance in wheat.

Apoptosis Induction in MV4-11 and K562 Human Leukemic Cells by Pereskia sacharosa (Cactaceae) Leaf Crude Extract

Asmaa, Mat Jusoh Siti,Al-Jamal, Hamid Ali Nagi,Ang, Cheng Yong,Asan, Jamaruddin Mat,Seeni, Azman,Johan, Muhammad Farid Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

Background: Pereskia sacharosa is a genus of cacti widely used in folk medicine for cancer-related treatment. Anti-proliferative effects have been studied in recent years against colon, breast, cervical and lung cancer cell lines, with promising results. We here extended study of anti-proliferative effects to a blood malignancy, leukemia. Materials and Methods: Two leukemic cell lines, MV4-11 (acute myeloid leukemia) and K562 (chronic myeloid leukemia), were studied. $IC_{50}$ concentrations were determined and apoptosis and cell cycle regulation were studied by flow cytometric analysis. The expression of apoptosis and cell-cycle related regulatory proteins was assessed by Western blotting. Results: P sacharosa inhibited growth of MV4-11 and K562 cells in a dose-dependent manner. The mode of cell death was via induction of intrinsic apoptotic pathways and cell cycle arrest. There was profound up-regulation of cytochrome c, caspases, p21 and p53 expression and repression of Akt and Bcl-2 expression in treated cells. Conclusions: These results suggest that P sacharosa induces leukemic cell death via apoptosis induction and changes in cell cycle checkpoint, thus deserves further study for anti-leukemic potential.

Chemical composition, antibacterial and antifungal activities of Thymus leptobotrys Murb essential oil

Asmaa Oubihi,Imane Ouryemchi,Issmail Nounah,Kelthoum Tarfaoui,Hicham Harhar,Mohammed Ouhssine,Zineb Guessous 경희대학교 융합한의과학연구소 2020 Oriental Pharmacy and Experimental Medicine Vol.20 No.4

The objective of this work is to study the chemical composition of Thymus leptobotrys Murb essential oil and its antimicrobial properties on ten bacteria and three yeasts. The essential oil is extracted by hydrodistillation and analyzed by gas chromatography coupled with mass spectrometry (GC/MS). The active substances are monoterpenic alcohols, mainly carvacrol (73.68%), and monoterpenic hydrocarbons: p-cymene (8.68%) and γ-terpinene (4.14%). The antibacterial and antifungal activity determined by disc diffusion method reveals an inhibitory effect of the essential oil on all studied strains, the potential for inhibition being greater than the reference antibiotics (Ciprofloxacin and Amoxicillin).