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      • KCI등재

        Impacts of Selection for Spike Length on Heat Stress Tolerance in Bread Wheat (Triticum aestivum L.)

        Asmaa M. Mohamed,Mohamed K. Omara,Mahmoud A. El-Rawy,Mohamed I. Hassan 한국육종학회 2019 Plant Breeding and Biotechnology Vol.7 No.2

        Two consecutive cycles of selection were imposed on five F2 populations of bread wheat. The first cycle was a divergent selection for spike length conducted in favorable environment (optimal sowing date) and the response was measured under favorable and heat stress conditions of a late sowing date. Positive responses to selection for longer spikes were obtained under favorable (13.43%) heat stress (8.66%) conditions, whereas the responses for shorter spikes were 2.24 and 5.02% in the two environments, respectively. The realized heritability of spike length was greater under favorable conditions (0.25-0.56) than under heat stress (0.18- 0.41). Concurrent positive responses to selection for longer spikes were obtained in grain yield per spike under favorable (25.35%) and heat stress (13.65%) environments. Selection for greater number of grains per spike imposed on F3 plants selected for spike length under heat stress resulted in significant responses (14.65%). Selection for greater number of grains per spike resulted in correlated responses in grain yield per spike (17.64%). The concurrent positive responses produced in spike length in F4 with selection for number of grains per spike (averaged 9.20%) was almost equal to that produced by the direct selection in F3 (8.66%), indicating that selection advance effected in F3 has been maintained in F4. High F4/F3 regression was obtained for spike length under heat stress (b = 0.85 ± 0.07), indicating high heritability. In conclusion, phenotypic selection for longer spikes under heat stress followed by a cycle of selection for number of grains per spike was capable of improving heat tolerance in wheat.

      • KCI등재

        Phytochemical and pharmacological screening of Sargassium vulgare from Suez Canal, Egypt

        Mohamed A. Shreadah,Nehad M. Abd El Moneam,Samy A. Al-Assar,Asmaa Nabil-A 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.4

        The current study investigates the phytochemical and pharmaceutical activities of Sargassium vulgare (SVE) collected from the Suez Canal. The prescreening using cytotoxicity was tested against hepatocellular carcinoma cell lines. Furthermore the SVE inhibit cell growth effectively with IC50 = 20.8 lg/ml. The pharmacological studies revealed high antioxidant capacity at all examined concentrations. On the meantime, anticancer assay carried out using tyrosine kinase (PTK) and sphingosine kinase 1 inhibitor screening assays revealed inhibition with 75.73 and 80.01%; respectively. Furthermore, the anti-inflammatory profiling revealed that the activities against COX1, COX2, IL6 and TNF were 77.39, 88.35, 75.38 and 71.24%; respectively. Additionally, the anti-Alzheimer results showed high activity at 1 mg with 76.33%. Finally the antiviral activities using reverse transcriptase inhibition assay give 92.24%. Consequently, it can be easily conclude that the SVE collected from the Suez Canal are excellent source of natural products for nutritional and pharmaceutical applications.

      • KCI등재

        Graphitic carbon nitride embedded Ni3(VO4)2/ZnCr2O4 Z-scheme photocatalyst for efficient degradation of p-chlorophenol and 5-fluorouracil, and genotoxic evaluation in Allium cepa

        M. Swedha,Abdulrahman A. Alatar,Mohammad K. Okla,Ibrahim A. Alaraidh,Asmaa Mohebaldin,Mohammed Aufy,Lija L. Raju,Ajith M. Thomas,Mostafa A. Abdel-Maksoud,S. Sudheer Khan 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.112 No.-

        Visible light photocatalysis using nano heterostructures offers an eco-friendly alternative for the removalof organic molecules. Here, we reported an enhanced photocatalytic activity of g-C3N4/Ni3(VO4)2/ZnCr2O4, a dual Z-scheme nano-heterojunction for the photocatalytic removal of p-chlorophenol (p-CP)and 5-fluorouracil (5-FU). The nano heterojunction was fabricated by a facile co-precipitation method. Initially, the fabricated nanocomposites (NCs) were characterized for Physico-chemical and optoelectronicproperties, by XRD, XPS, SEM, TEM, UV–Visible DRS, BET, PL, and EIS. The fabricated g-C3N4/Ni3(VO4)2/ZnCr2O4 has shown excellent photocatalytic activity. The complete mineralization of both p-CP and 5-FU observed after 160 and 200 min of visible light irradiation respectively. The mineralizationof p-CP and 5-FU was confirmed by total organic carbon (TOC) estimation and the percentage of removalTOC for p-CP and 5-FU was 99.25% and 98.9% respectively. The stability of the particle was confirmed bysix cycles test. The reusable efficiency of the NCs was found to be 99.7% after six consequent cycles. Thestability of the NCs was confirmed by XRD and XPS analysis of reused photocatalyst. The scavengers assayand ESR analysis confirmed the major role of OH radicals in enhanced photocatalytic activity. The degradationpathway of p-CP and 5-FU was determined by GC–MS/MS and the possible toxicity of the intermediatecompounds was determined by the ECOSAR program, which shows the non-toxic nature ofthe end product on green algae, daphnia, and fish. The toxicity of the NCs was tested against Allium cepawhich further confirm the non-toxic nature of NCs. The study suggests that fabricated g-C3N4/Ni3(VO4)2/ZnCr2O4 NCs can be utilized for environmental remediation applications.

      • KCI등재

        New Optimization Model for Multi-Period Multi-Product Production Planning System with Uncertainty

        Asmaa A. Mahmoud,Mohamed F. Aly,Ahmed M. Mohib,Islam H. Afefy 대한산업공학회 2019 Industrial Engineeering & Management Systems Vol.18 No.4

        The focus of this study is to develop a multi-period multi-product (MPMP) production planning system with uncertainty, and products demand (seasonal demand) uncertainty. Mainly, the problem aims reach the production levels ofeach product according to the uncertain demand for various periods, which depend on constraints of capacity, inventory, and resources. An analytical model proposed for this problem that can be categorized into two classes: non-linearand stochastic. The objective is to minimize the summation of variable production costs. As uncertain demand is adynamic stochastic data process in the planning horizon, it is considered as a tree model. Each stage in the demandtree model is related to a cluster of a period time. Hence, depending on the tree model for the fluctuation demand;Two-Stage Stochastic Programming (TSP) model is presented as an alternative for all demand scenarios. In some ofthe reviewed articles validation of the analytical model were missing, while other studies were missing either manufacturing set up costs or assumptions of seasonal demand. Therefore, this study proposes TSP model using SamplingAverage Approximation method (SAA) that is suitable for a production planning system in any manufacturing environment considering seasonal demand using optimization program (Lingo 16) to solve the mathematical model. Further, investigation of seasonal demand is performed using the multiplicative seasonal method, and the model validation was checked using Mathworks Matlab R2015a (64-Bit) considering manufacturing set up costs. Finally, somerecommendations for future research are suggested.

      • SCOPUSKCI등재

        NEW SERIES IDENTITIES FOR ${\frac{1}{\Pi}}$

        Awad, Mohammed M.,Mohammed, Asmaa O.,Rakha, Medhat A.,Rathie, Arjun K. Korean Mathematical Society 2017 대한수학회논문집 Vol.32 No.4

        In the theory of hypergeometric and generalized hypergeometric series, classical summation theorems have been found interesting applications in obtaining various series identities for ${\Pi}$, ${\Pi}^2$ and ${\frac{1}{\Pi}}$. The aim of this research paper is to provide twelve general formulas for ${\frac{1}{\Pi}}$. On specializing the parameters, a large number of very interesting series identities for ${\frac{1}{\Pi}}$ not previously appeared in the literature have been obtained. Also, several other results for multiples of ${\Pi}$, ${\Pi}^2$, ${\frac{1}{{\Pi}^2}}$, ${\frac{1}{{\Pi}^3}}$ and ${\frac{1}{\sqrt{\Pi}}}$ have been obtained. The results are established with the help of the extensions of classical Gauss's summation theorem available in the literature.

      • KCI등재

        Efficacy of dietary propolis and its nanoparticles on immune- response, stress indicators, and prevention of Pseudomonas aeruginosa infection in Oreochromis niloticus

        Fatma M. M. Korni,Asmaa N. Mohammed,Usama K. Moawad,Nour El-Houda y. Hassan,Ahmed Farghali,Rehab K. Mahmoud 한국어병학회 2023 한국어병학회지 Vol.36 No.1

        Nanotechnology seeks to improve material effectiveness to have a greater impact on medicine. The current study was performed to determine how effective dietary propolis (PR) and propolis nanoparticles (PR-NPs) were at improving immune and anti-oxidant status, lowering cortisol levels as stress indicators, and preventing Pseudomonas aeruginosa infection in O. niloticus. Histopathology was carried out. Fish (N = 516, 25 ± 2g) were fed basal diets supplemented with 1 gm PR/kg, 2 gm PR/kg, 1 gm PR-NPs/kg, 2 gm PR-NPs/kg feed and control diet for 28 days. When compared to the control, interlukin-1, IgM, complement 5, and levels of lysozyme were dramatically higher in PR and PR-NPs fed-groups. Antioxidant enzymes and glutathione levels were higher in fish fed PR and PR-NPs, but malondialdehyde levels were lower. Cortisol levels decreased in feeding groups compared to the control. When compared to O. niloticus group fed 1 gm PR/kg and the positive control, propolis nanoparticles successfully prevented P. aeruginosa infection and the mortality rate was zero. When compared to the negative control, the positive control group's histopathological findings revealed severe histopathological changes. In low and high groups fed PR-NPS, normal structures were observed as well as high concentrations of PR after being injected with P. aeruginosa. The group that was fed low concentrations of PR after being injected with P. aeruginosa showed only minor histopathological changes. Conclusion: Dietary supplementation of PR or PR-NPs may have a beneficial effect on aquaculture, with PR-NPs having a superior effect.

      • SCOPUSKCI등재

        Biosurfactant Production by Marine Actinomycetes Isolates Streptomyces althioticus RG3 and Streptomyces californicus RG8 as Promising Sources of Antimicrobial and Antifouling Effects

        ( Moaz M. Hamed ),( Mohamed A. A. Abdrabo ),( Asmaa M. Youssif ) 한국미생물 · 생명공학회 2021 한국미생물·생명공학회지 Vol.49 No.3

        Two marine actinobacterial isolates, RG3 and RG8, were identified using 16Sr DNA as Streptomyces althioticus RG3 and Streptomyces californicus RG8 and submitted to the database of genetic information with accession numbers MW661230 and MW661234, respectively; they were found to have emulsification indexes of 60 ± 2.5% and 53 ± 2.2%, respectively. The biosurfactants obtained were stable at a temperature of 35_ for both strains; they were stable at 10% NaCl, in the case of S. althioticus RG3 and at 10-15% NaCl in the case of Str._ californicus RG8; both strains produced the most biosurfactant when exposed to alkaline conditions. We characterized the biosurfactants, including features such as their chemical composition, using Fourier transform infrared spectroscopy analysis. The antimicrobial activity of the biosurfactant extracts was evaluated using the well diffusion method against Vibrio alginolyticus MK170250, Escherichia coli ATCC 8739, Pseudomonas aeruginosa ATCC 4027, and Staphylococcus aureus ATCC 25923. S. althioticus RG3 biosurfactants were found to have better antimicrobial activity than those of Str. californicus RG8, indicating that they may be used in pharmaceutical industries and in the manufacture of antifouling products.

      • SCOPUSKCI등재

        ON AN INTERESTING EXTENSION OF KUMMER'S SECOND THEOREM WITH APPLICATIONS

        Awad, Mohammed M.,Mohammed, Asmaa O.,Rakha, Medhat A.,Rathie, Arjun K. Korean Mathematical Society 2021 대한수학회논문집 Vol.36 No.1

        In this research paper, an attempt has been made to provide an interesting extension of the well-known and useful Kummer's second theorem. Several applications have also been given.

      • SCIESCOPUSKCI등재

        Impact of Seasonal Conditions on Quality and Pathogens Content of Milk in Friesian Cows

        Zeinhom, Mohamed M.A.,Abdel Aziz, Rabie L.,Mohammed, Asmaa N.,Bernabucci, Umberto Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.8

        Heat stress negatively affects milk quality altering its nutritive value and cheese making properties. This study aimed at assessing the impact of seasonal microclimatic conditions on milk quality of Friesian cows. The study was carried out in a dairy farm from June 2013 to May 2014 at Beni-Suef province, Egypt. Inside the barn daily ambient temperature and relative humidity were recorded and used to calculate the daily maximum temperature-humidity index (mxTHI), which was used as indicator of the degree of heat stress. The study was carried out in three periods according to the temperature-humidity index (THI) recorded: from June 2013 to September 2013 (mxTHI>78), from October 2013 to November 2013 (mxTHI 72-78) and from December 2013 to April 2014 (mxTHI<72). Eighty Friesian lactating dairy cows were monitored in each period. The three groups of cows were balanced for days in milk and parity. Milk quality data referred to somatic cell count, total coliform count (TCC), faecal coliform count (FCC), Escherichia coli count, percentage of E. coli, and Staphylococcus aureus, percentage of fat, protein, lactose, total solid and solid non-fat. Increasing THI was associated with a significant decrease in all milk main components. An increase of TCC, FCC, and E. coli count from mxTHI<72 to mxTHI>78 was observed. In addition, the isolation rate of both S. aureus and E. coli increased when the mxTHI increased. The results of this study show the seriousness of the negative effects of hot conditions on milk composition and mammary gland pathogens. These facts warrant the importance of adopting mitigation strategies to alleviate negative consequences of heat stress in dairy cows and for limiting related economic losses.

      • KCI등재

        Prevention of Citrobacter freundii (MW279218) infection in Nile tilapia, Oreochromis niloticus using zinc oxide nanoparticles

        Korni, Fatma M. M.,Moawad, Usama K.,Mohammed, Asmaa N.,Edrees, Asmaa The Korean Society of Fish Pathology 2022 한국어병학회지 Vol.35 No.1

        Aquaculture development is based on the ideas of increasing production while reducing economic losses. Bacterial diseases are the leading source of fish cases. Citrobacter freundii has been linked to septicemia and mortality all over the world. In the current study, the cause of mortality in O. niloticus was C. freundii MW279218. External hemorrhages were seen on the affected fish, as well as paleness in the liver and kidney congestion. C. freundii MW279218 had a median lethal dosage of 1.5×10<sup>5</sup> CFU/mL. Zinc oxide and zinc oxide nanoparticles (ZnO-NPs) were tested for their biocidal effectiveness against C. freundii MW279218. The lethal effect of ZnO-NPs for C. freundii MW279218 was 100% when compared to zinc oxide compound, and the inhibition zone width was 2.31.1mm at the highest tested concentrations (70 mg/L) compared to the lowest (35 and 45 mg/L, respectively). Fish were fed three different diets for 28 days: diet 1 (no additives), diet 2 (100 mg of ZnO-NPs/kg of feed), and diet 3 (200 mg of ZnO-NPs/kg of feed). Organs were also collected for histopathology 96 hours after injection (P<0.05). In the groups given 200 mg of ZnO-NPs, there was 10% mortality and 80% RPS. The group fed 100 mg of ZnO-NPs/kg, on the other hand, had 20% mortality and 60% RPS, compared to 50% mortality in the control positive group. Histopathological examinations demonstrated significant alterations in the control positive group and mild lesions in the hepatopancreas of the groups administered 100 mg ZnO-NPs/kg of feed. The groups fed 200 mg of ZnO-NPs/kg diet, on the other hand, showed no histological alterations. ZnO-NPs were found to be effective in the up regulation of both IL-10 and complement 5 immune-related genes.

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