Developed a high-performance sensor based on cumarin derivative for rapid and sensitive detection of palladium ion in organic wastewater

Ai-min Ren,Yu Zhang,Weiwei Yu,Kai Zhao,Zhiru Hu,Zhiquan Zhang,Guodong Feng,Zhi-Guang Song 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.99 No.-

In this article, a series of coumarin derivativefluorescent probes have been synthesized, which can realizesimple, rapid and sensitive detection of Pd2+. We tested thefluorescence properties of threefluorescentprobes, (E)-N0-(((4-chloropyridin-2-yl) methylene)-7-(diethylamino)-2-oxo-2H-chromene-3-carbohy(CMDCC) has the betterfluorescence properties and anti-interference ability. Then, CMDCC as thefluorescence probe for detection of Pd2+ was systematic studied. Under optimized conditions, this probehas a wide pH range, a lower detection limit (4.4510 8 mol L-1), and a faster response speed (3 min). Inthe Pd2+ concentration range of 0.1 5 mmol L-1, thefluorescence intensity of this probe and concentrationof Pd2+ show a good linear response. In this work, Pd2+ content in organic waste liquid was successfullydetected and a standard addition test was also performed. The satisfactory recovery rate was obtained. Moreover, it can be observed with naked eyes that the palladium ion changes the solution color of CMDCCfrom green to red. This color change can easily be compared with other metal salts. It indicates thatCMDCC can also detect Pd2+ by colorimetric method. Therefore, CMDCC should be used to rapidly,conveniently detect Pd2+ in environmental samples.

MR Imaging of the Spine at 3.0T with T2-Weighted IDEAL Fast Recovery Fast Spin-Echo Technique

Ai-Jun Ren,Yong Guo,Shu-Ping Tian,Li-Jing Shi,Min-Hua Huang 대한영상의학회 2012 Korean Journal of Radiology Vol.13 No.1

Objective: To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine. Materials and Methods: Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDEAL FRFSE images. Signal-to-noise ratio (SNR)-efficiencies measurements were made in the vertebral bodies and spinal cord in the mid-sagittal plane or nearest to the mid-sagittal plane. Images were scored with the consensus of two experienced radiologists on a four-point grading scale for fat suppression and overall image quality. Statistical analysis of SNR-efficiency, fat suppression and image quality scores was performed with a paired Student’s t test and Wilcoxon’s signed rank test. Results: Signal-to-noise ratio-efficiency for both vertebral body and spinal cord was higher with T2W IDEAL FRFSE imaging (p < 0.05) than with T2W FRFSE imaging. T2W IDEAL FRFSE demonstrated superior fat suppression (p < 0.01) and image quality (p < 0.01) compared to fat-saturated T2W FRFSE. Conclusion: As compared with fat-saturated T2W FRFSE, IDEAL can provide a higher image quality, higher SNR-efficiency, and consistent, robust and uniform fat suppression. T2W IDEAL FRFSE is a promising technique for MR imaging of the spine at 3.0T. Objective: To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine. Materials and Methods: Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDEAL FRFSE images. Signal-to-noise ratio (SNR)-efficiencies measurements were made in the vertebral bodies and spinal cord in the mid-sagittal plane or nearest to the mid-sagittal plane. Images were scored with the consensus of two experienced radiologists on a four-point grading scale for fat suppression and overall image quality. Statistical analysis of SNR-efficiency, fat suppression and image quality scores was performed with a paired Student’s t test and Wilcoxon’s signed rank test. Results: Signal-to-noise ratio-efficiency for both vertebral body and spinal cord was higher with T2W IDEAL FRFSE imaging (p < 0.05) than with T2W FRFSE imaging. T2W IDEAL FRFSE demonstrated superior fat suppression (p < 0.01) and image quality (p < 0.01) compared to fat-saturated T2W FRFSE. Conclusion: As compared with fat-saturated T2W FRFSE, IDEAL can provide a higher image quality, higher SNR-efficiency, and consistent, robust and uniform fat suppression. T2W IDEAL FRFSE is a promising technique for MR imaging of the spine at 3.0T.

Evidence mapping of interactions on concomitant use of Chinese medicine and platinum-based chemotherapy: a scoping review protocol

Ai Ch’i Liew,Si Yan Chan,Ren Jye Lim,Wan Najbah Nik Nabil,Shi Min Hoo,Nai Ming Lai 한국한의학연구원 2020 Integrative Medicine Research Vol.9 No.2

Background: The utilization of Chinese herbal medicine (CHM) has gained popularity and acceptance worldwide. Increasing use of CHM either as a stand-alone or an adjunctive treatment for cancers has given rise to increasing concern on potential herbal-drug reactions. Possible combinatory effects are important to be explored in evaluating the rationality of integrating CHM and chemotherapy in clinical practice. This study aims to update the current knowledge on herbal-drug interactions (HDI) of the commonly used platinum-based chemotherapy (PtC) in cancer patients. Methods: Systemic searches will perform on online databases (English and Chinese) to identify papers from inception until December 2019 for inclusion into the review. The search strategy will be following PRISMA Scoping Reviews Checklist as a quality assurance step. All records retrieved will be screened by 2 independent reviewers. The preclinical studies and clinical studies that involve in assessing the concurrent use of CHM and PtC will be considered. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses will be used as scoping review framework. Discussion: This scoping review will explore the compatibility or combination rule of CHM-PtC and assist in understanding HDI in CHM-PtC co-treatment. Identification of active properties in CHM’s HDI and understanding pharmacokinetics and pharmacodynamic of the CHM alone or as co-treatment are essential for patients’ safety profile. It will provide a new insight for future practice in cancer treatment. Study registration: This protocol has been registered in the Research Register (https://www.researchregistry.com/) with an unique registration number: reviewregistry790.

Theoretical Study of the Relationships between Excited State Geometry Changes and Emission Energies of Oxyluciferin

Li, Zhong-Wei,Min, Chun-Gang,Ren, Ai-Min,Guo, Jing-Fu,Goddard, John D.,Feng, Ji-Kang,Zuo, Liang Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.4

In order to find a relationship between firefly luciferases structure and bioluminescence spectra, we focus on excited substrate geometries which may be affected by rigid luciferases. Density functional theory (DFT) and time dependent DFT (TDDFT) were employed. Changes in only six bond lengths of the excited substrate are important in determining the emission spectra. Analysis of these bonds suggests the mechanism whereby luciferases restrict more or less the excited substrate geometries and to produce multicolor bioluminescence.

Theoretical Study of the Relationships between Excited State Geometry Changes and Emission Energies of Oxyluciferin

Zhong-wei Li,Chun-gang Min,Ai-min Ren,Jing-fu Guo,John D. Goddard,Ji-kang Feng,Liang Zuo 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.4

In order to find a relationship between firefly luciferases structure and bioluminescence spectra, we focus on excited substrate geometries which may be affected by rigid luciferases. Density functional theory (DFT) and time dependent DFT (TDDFT) were employed. Changes in only six bond lengths of the excited substrate are important in determining the emission spectra. Analysis of these bonds suggests the mechanism whereby luciferases restrict more or less the excited substrate geometries and to produce multicolor bioluminescence.