장기간의 Cyclosporine 유지 요법으로 신기능을 유지 중인 FSGS 2예

권순길,김상현,김수희,박은주,이은경,박수길 대한신장학회 2004 대한신장학회잡지 Vol.23 No.1

Vitamin D_(3)가 RAW 세포에 감염된 Mycobacterium marinum의 증식억제에 미치는 기전 연구

박정규,정샛별,이길수,김수영,송창화,박종호,조현구,조은경,김화중 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

The natural resistance-associated macrophage protein 1(Nramp1) has been proposed to directly regulate bactericidal or bacteriostatic activity of the macrophage toward pathogens or participate in macrophage activation that lead to microbial elimination in the host. The relationship between Nramp1 and nitric oxide(NO) as an antimicrobial factor has not been precisely defined to date. To devise an in vitro assay for Nramp1 function, this study introduced a wild type Nramp1^(G169) cDKA transfected RAW264.7 macrophages(A8) which bear a homozygous mutant Nramp1^(D169) allele and are permissive to replication of specific intracellular parasites. RAW264.7 and A8 macrophages did not produce NO, but vitamin D_(3)-activated-Mycobacterium marinum-infected RAW264.7 and A8 macrophages pretreated with vitamin D_(3) leaded to the increase of NO production and growth inhibition of M. marinum. Inhibition of NO production by a NO inhibitor, L-NAME, abolished the above effects. The mRNA expression of iNOS in infected macrophages with costimulated vitamin D_(3) was increased. IFN-γ activated macrophages also showed the same results with vitamin D_(3) activated macrophages. These results suggest that bactericidal or bacteriostatic activity in RAW264.7 and A8 macrophages correlated with the production of NO, although NO might not be the only factor responsible for controlling M. marinum infection. The Nrampl gene is considered to be a cofactor in the controlling the replication of M. marinum infection.

환자, 간호사, 의사가 지각하는 교육요구도와 교육제공정도에 관한 연구

박인숙,문영숙,조미경,최은숙,이경숙,정길수 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

The purpose of this study was to provide the basic data for the planning of education of patients by exploring and comparing patients', nurses' and doctors' perception of the educational needs and degree of providing education. 66 hospitalized patients undergoing chemotherapy and 44 nurses, 42 doctors assigned for the direct care were sampled in 1 university hospital in Taejon from August 30, 1993 to September 30, 1993. For the comparing patients', nurses' and doctors' perecption of the educational needs and degree of providing education, the researcher used Kims' Educational need scale which is composed of 20 item Likert type 5 point scale. Data were analyzed by means of percentile score, SPSS, t-test, ANOVA, Pearson correlation. The result were as follows 1. Comparision of total Mean score patients', nurses' and doctors' perception of the educational need ordering nurses(M=4.0465), patients (M=3.9803), doctors (M=3.8309). The difference between the three group's total Mean score is showed no statistical significant difference. 2. Comparision of total Mean score patients' educational need, patients' percetion of nurses' and doctors' degree of providing education, patients' educational need is scored 3.9803, patients' perception of nurse is scored 2.3431, patients' perception of doctor is scored 2.5022. The difference between the patients' educational need and medical teams' degree of providing education is showed statistical significant difference(P<.001). 3. Comparision of total mean score nurses' educational need is scored 4.0465, nurses' perception of nurses' degree of providing education is scored 2.9920, patients' perception of nurses' degree of providing education is scored 2.3431. The difference of between the nurses' educational need and nurses' perception of nurses' degree of providing education is showed statistical significant difference(P<.001) 4. Comparision of total mean score doctors' educational need is scored 3.8309, doctors' perception of doctors' degree of providing eduation is scored 3.1726, patients' perception of doctors' degree of providing education is scored 2.5022. The difference of between the doctors' educational need and doctors' perception of doctors' degree of providing education is showed statistical difference(P<.001).

고주파 공진형 인버터식 X선발생장치의 관전압 불균형 개선

이성길,김영근,박수강 광주보건대학 2000 論文集 Vol.25 No.-

In order to radiate X-ray, the low ripple stabilized high voltage DC over the range of 40kV to 150kV is directly inflicted to X-ray tube. The energy characteristics of the radiated X-ray depend on the pulsating waveforms of the DC voltage supplied X -ray tube. In general, the low ripple voltage waveforms with fast rising times are required to increase with the dosage per unit time lest the exposure time should be longer in order that the motion artifacts of an object may be eliminated in actual. The rotating anode and the cathode of the metal-envelope X-ray tube are incorporated into an envelope made of metal, for instance stainless steel and copper, instead of hard glass. This metal envelope is able to collect the secondary electrons which causes harmful influence to thequality of the diagnostic images. Furthermore, the metal-envelope X-ray tube has mechanically higher strength than glass-envelope type, and so it suits for high power X-ray system. For those benefits, this type of X-ray tube is mainly used to obtain the high quality diagnostic images in X-ray angiography and X-ray computed tomography. The electrons collected at th envelope generate the eletric current flow form the ground to the cathode and occasionally the unmatched impedance of the anode side and the cathode side of the X-ray tube. The unmatched impedance causes the remarkable imblacne of the output voltage of the series resonant inverter-fed converter. In this paper, the newly-developed converter to take the balance of the output voltage versus the ground are also presented in detail. This converter consists of the two independent series resonant circuit using the two capacitance and the two parimary winding high-voltage transformer.

PWM 인버터를 이용한 단상유도전동기의 보조권선제어

이성길,김영근,박수강 광주보건대학 2002 論文集 Vol.27 No.-

In this paper, an auxiliary winding driving system of single - phase induction motors is described. Starting time variations are obtained by controlling the auxiliary winding voltage magnitude and phase angle, while the motor's main winding is directly connected to the local utility. A variable auxiliary winding voltage phase angle is shown to yield significant torque control, providing starting and braking torque. The analysis includes the determination of the relationship between the auxiliary winding voltage phase angle and the phase angle difference between the main and auxiliary winding current. The paper proposed for adjusting an auxiliary winding voltage magnitude and phase angle. Experimental results of motor's starting characteristics with using the PWM inverter for auxiliary winding power supply are shown. The drive is tested using a dynamometer to experimentally verify the results of the theory.

LC 공진형 PWM 인버터를 이용한 X선 발생장치의 특성에 관한 연구

이성길,박수강,임홍우,조금배,백형래,임양수 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.1

The conventional types of X-ray generators were bulky in physical size and heavy in weight, and the control accuracies of the output voltages were not always satisfactory. The high frequency switching inverter and converter technology on power conversion and control systems have been greatly closed up introducing power semiconductor devices. In this paper, the newly developed converter to take the balance of the output voltage versus the ground are also presented in detail to decreasing the volume and the weight of high voltage transformer and to stabilize ripple. This converter consists of the two independent L-C series resonant circuits using the two capacitances and the two primary windings of high voltage transformer.

히피 헤어스타일과 패션의 의미 및 영향에 관한 연구

李水仁,朴吉順 服飾文化學會 1999 服飾文化硏究 Vol.7 No.4

The study has the aim to now the significance of hippe dress and hairstyle and to understand the influence upon them in 1990'. The results of this study are as follow. First, the results of the significance of hippie dress and hairstyle in 1960' which had analized by the basis of pierce's semiotic theory showed social resistence, piece and anti-war, psychodelic, ethnic and nostalgia, and individualism. Second, studying the character of the end of 1990' when hippie dress and hairstyle reappeared through realted the papers, magazine, and articles, we could get the phenomenon of pastiche, postmodernism which had excepted the spiritual significance of hippie in 1960'.

단상유도전동기의 부하적응형 위상제어시스템 설계

이성길,김승국,박수강 광주보건대학 2003 論文集 Vol.28 No.-

The three-phase induction motor is rugged, reliable, long-lived, self-starting, smooth-running. But it is relatively inexpensive and three-phase power in not available everywhere, so if possible we need single-phase motor with the same characteristics. In fact, single-phase induction motors have excellent characteristics and outnumber the three-phase variety. Most of the small electric motors used in home, farm, or office are single-phase induction motors of one type or another. This electric motors application field need most energy saving type drive according to enlargement of electronic goods and to tend high class. The paper is proposed a various phase control methods for energy saving of single- phase induction motor. The controllers that are embodied by each method can use by various usage according to each performance and it is considered that application may help in the electrical energy saving because is possible to other electrical appliances.

PFC를 적용한 AC/DC 승압형 컨버터 설계

백형래,박수강,최연옥,한엄용,이성길 조선대학교 에너지.자원신기술연구소 1999 에너지·자원신기술연구소 논문지 Vol.21 No.1

Single-Phase diode rectifiers are widely used in industry. These rectifier, however, generate many harmonic components in the AC Power line and have the poor input power factor, which may create a power quality problem for other electrical apparatus in the vicinity of the rectifier. Power factor improvement and harmonic reduction in the AC line current have become very significant problems in single-phase diode rectifiers. In this paper, the high power factor boost converter using soft switching is proposed to improve the demerit. The simulation results show the validity of the proposed system.

Furfural 어류급독성 및 조직병리에 관한 연구

이철우,최성수,최필선,이상협,이길철,박광식 한국환경독성학회 1997 환경독성보건학회지 Vol.12 No.2

Furfural, an organic solvent, is widely used as synthetic component material in producing chemical products. However, furfural has been reported that it shows strong toxicities to human being showing intense stimulus to skin, eyes, mucous membrane and nerve system. It is also known to cause anemia, liver cirrhosis, kidney failure and genetic toxicity in the human being working in the exposed area. LD50 of furfural for peritoneal injected mouse has been known around 20mg/kg, but the acute toxicity on aquatic organisms such as fish, daphnid or algae are not well known, compared to those on rodents. In this experiment, we studied on the fish toxicity of furfural using Japanese Meclaka (Oryzias latipes) and Common Carp (Cyprinus carpio). We also observed histological changes in the fish organs. The LC50s were 12.8 mg/L in Japanese Medaka and 21.8 mg/L in Common Carp, respectively. When Common Carps were exposed to 120 mg/L of furfural concentration for 30 minutes, blood congestion in gills and lysis of secondary lamella were shown. Though the muscle of caudal fin was not completely eroded, its epidermic cells were shown to be necrotic in various parts. Tissue atrophy and cell necrosis were also shown in the liver of Common Carps exposed to furfural. From these results, furfural seems to cause histological damages on liver, an internal organ as well as on external organs such as gills and fins eventhough the fish were exposed for a short-term.