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      • KCI등재

        푸른길 공원의 대기 환경 특성에 관한 연구

        민경우,이경석,박옥현,윤관주,김도술,박세일,정원삼,이대행,조영관,Min, Kyoung-Woo,Lee, Kyoung-Soek,Park, Ok-Hyun,Yoon, Kwan-Ju,Kim, Do-Sool,Park, Se-Il,Jeung, Won-Sam,Lee, Dae-Hang,Cho, Young-Gwan 한국환경보건학회 2015 한국환경보건학회지 Vol.41 No.3

        Objectives: This study aimed to survey the characteristics of air quality and meteorological conditions in a greenway park. Methods: We measured meteorological and health related factors, including noise, particulate matter ($PM_{10}$) and selected gaseous air pollutants at three locations in a greenway park and on a general roadside as comparison. The measurements were repeated four times from April to October 2014. Results: The average air temperature in the greenway park was $20.7^{\circ}C$ which was $1-2^{\circ}C$ lower than on the general roadside. The average $PM_{10}$ concentration in the greenway park was $85.0{\mu}g/m^3$, a level 2-3 times lower than that at the roadside. The noise level at the greenway site was 4.4 dB(A)- 23.0 dB(A) lower than at the roadside. The average CO, $CO_2$, $SO_2$ and NOx concentrations in the greenway park were lower than at the roadside. The average phytoncide and anions concentrations in the greenway park were higher than at the roadside. Conclusions: The urban forest of the greenway park may have some impact on air quality and meteorological conditions.

      • 한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

        양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

      • KCI등재
      • KCI등재

        韓醫學的 診斷類型에 따른 韓藥方劑의 抗癌 및 免疫調節作用에 미치는 影響

        朴鐘鉉,金楨氾,崔昇勳,安圭錫 대한동의병리학회 1994 동의생리병리학회지 Vol.9 No.1

        연구배경 : 암은 사망의 주요한 원인이 되는 질환으로서, 우리나라에 있어서도 급격히 증가하는 추세이다. 한의학에서는 암의 유형을 크게 간울기체형, 기체혈어형, 비허습담형, 음허내열형 등으로 분류하고 있는데, 각 유형에 응용할 수 있는 소요산, 소복축어탕, 사군자탕, 육미지황탕의 항암효능을 비교 연구함으로써, 암치료에 대한 한약재의 임상활용도를 높이고자 함. 방법 : Mouse에 Sarcoma-180으로 복강암을 유발한 후, 약제를 21일 간 투여하고 생존율, T cell, B cell, 혈청항체가, IL-2 생산능, NK cell의 세포살상능을 측정하였다. 결과 : 생존기간의 연장효과는 모든군에서 증가하는 경향이 있었으나 유의성이 없었고, T cell 및 B cell은 모든군에서 증가하였으며, 임파구 증식반응 및 IL-2 생산능은 사군자탕과 육미지황탕에서, NK cell 활성도는 소복축어탕 엑기스 투여군에서 유의성이 있었다. 결론 : 이상으로 보아 이들 처방은 면역조절작용을 통한 항암효과가 있을 것으로 볼 수 있으며, 변증분형에 따라 처방을 달리해야 함을 알 수 있다. In order to investigate the effects of Formules according to Pattern Identification on anti-tumor and immunodulatory reaction to the ICR and C57BL/6 mice which have abdominal tumor after Sarcoma-180 cells were transplanted, the extracts of herbal medicines above mentioned were orally administered to the mice for 21 days to observe the extention of survial duration of the mice, quantitation of T cells and B cells, productivity of interleukin-2, lymphocytes transformation, hemagglutinin titer and hemolysin titer and activity of splenic natural killer cells. The results are summarized as follows ; 1. In the effect of life extention, all groups appeared to survive longer than the Control group, which are not meaningful. 2. Considering T cell and B cell content, all groups had a meaningful increase in both T cell and B cell (P<0.01). 3. Considering serum antibody titer was no significant difference between all groups. 4. In lymphocyte transformation marked a significant increase the sijunzitang-medicated mice group, marked a significant (P<0.01), and showed a significant increase the mice group medicated with Liuweidihuangtang (P<0.05). 5. As for the productivity of interleukin-2, showed a significant increase the mice group medicated with Sijunzitang ans Liuweidihuangtang (P<0.05). 6. In the effect of activity of NK cells, Shaofuzhuyutang-medicated mice group had a meaningful increase (P<0.05).

      • 위암세포에 의한 종양침윤 림프구의 면역반응 억제기전에 관한 연구

        박정규,송규상,서광선,최정목,배진선,장일성,윤완희,노승무,조은경,백태현 大韓免疫學會 1995 大韓免疫學會誌 Vol.17 No.3

        Tumor-infiltrating lymphocytes ('1°ILs) interact most closely with tumor cells and thus are more likely to reflect tumor host interactions accurately. But it is unknown whether such T cells are nonspecific inflammatory cells or a subset of specific host immune responses. In this study, there was no clear correlation between the infiltration of T lymphocytes in stomach cancer and the overexpression of c-ErbB-2 or increasing class I MHC expression on tumor cells. A positive correlation was seen between the presence of TILs in the tumor and tumors with diploidy by flow cytometric DNA analysis. The proliferative responses of Ills stimulated with IL-2, anti-CD3 mAb, or both were examined. When compared to normal mucosal-associated lymphoid tissue lymphocytes, the proliferative response of TILs to high dose IL-2 was minimal. A similarly poor response to anti-CD3 mAb plus IL-2 was also observed. The freshly isolated TILs exhibit reduced ability to proliferate in response to IL-2, anti-CD3 mAb or both. The microenvironment of the tumor suppresses the proliferative capacity of the TILs. The mechanism of this suppression remains unknown. It could be mediated by suppressor cells, by soluble substances within the tumor, or both. To examine this question, supernatants of stomach cancer cells (SNSNU-1) were tested for the presence of immunosuppressive factors. Human peripheral blood T-cells and tumor-draining lymph node lymphocytes (TDLNL) were incubated for 3 days with SNSNU-1 and then assessed for proliferative responses to PMA, anti-CD28 mAb, or both and for the inducibility to express IFN- r or IL-4 mRNA to PMA. Peripheral blood T-cells pretreated with SNSNU-1 were unable to proliferate in response to PMA, anti-CD28 mAb or both. SNSNU-1 also produces inhibitory activities of TDLNL proliferative response to PMA or anti-CD28 mAb and PMA (49%, 52%, respectively). In contrast, culture supernatants obtained from HEp-2, K562 or Daudi showed normal proliferative responsiveness of peripheral blood T-cells and TDLNL by PMA, anti-CD28 mAb or both.

      • CORBA 디자인 패턴에 관한 연구

        김정현,박세명,최항묵 인제대학교 2001 仁濟論叢 Vol.16 No.1

        소프트웨어의 객체지향 패러다임이 줄 수 있는 가장 큰 이점은 다형성(polymorphism)을 통한 재사용성(reusability)이다. 이러한 재사용성은 구현측면에서 코드의 재사용, 그래픽 사용자 인터페이스의 재사용, 분산 시스템에서의 인터페이스의 재사용에서는 잘 이루어지고 있으나, 설계단계에서의 재사용성은 아직 부족한 실정이다. 본 연구에서는 이러한 객체지향 설계단계에서 재사용할 수 있는 디자인 패턴(Design Pattern)으로서 분산 객체 환경인 CORBA 시스템 설계 시 적용할 수 있는 새로운 CORBA 디자인패턴을 제안한다. Designing object-oriented software is hard, and designing reusable object-oriented software is even harder. Design should be specific to the problem at hand but also general enough to address future problem and requirement. Expert Designers reuse solutions that have worked for them in the past. This solution is Design Pattern. The propose of this paper is to record experience in designing distributed-object CORBA software as CORBA design pattern.

      • 제주도 용천수의 지역별 수량변화

        윤정수,박상운,강석수,현영진 제주대학교 환경연구소 1998 환경연구논문집 : 제주대 Vol.6 No.-

        This study purposes to elucidate the effects of changes in precipitation and tide level on the spring water discharge quantity in Cheju Island. For this purposes. local and seasonal variations of discharge quantity have been measured at representive 19 springs covering the entire Island. In the middle mountain region, the discharge quantity is largely influenced by the precipitation, but it has a little relationship with the precipitation in the western region and the southern region. In the eastern region, influence of tide is larger than the precipitation, and the northern region is influenced by both precipitation and tide. In the entire study area, the spring water discharge reaches at maximum in the wet season of July, and shows minimum in the dry season from December to February. The discharge variation in the middle mountain and north regions is two to three times as large as that in the other regions. The comparison of the results of ths study with existing data shows discharge increase at the inch'onk'mul(about 6.000㎥) in the eastern region, Kwakgimul(about 7,000㎥) in the western region, Kangjungchun (about 11.000㎥ : WRDC), Jaguri(about 5,000㎥ : AFDC), Gongchunpo (about 3.000㎥) in the southern region, Yongyeanchun(about 1,500㎥) in the northern region, whde the discharge decrease at Sernurungmul(about 5,000㎥) in the eastern region, Ongpochun(about 10.000㎥) in the western region, Hwasun Dokmul(about 1,500㎥), Kangjungchun( about 28,000㎥ : AFDC), Jaguri(about 43,000㎥ ; WRDC) in the southern region, Sanjimul( about 3.500m3), Oleamul( about 6,200m3) in the northern region. In the Yongyeanchun, tide intimately influences quantity, electrical conductivity, level and temperature of spring water. The spring water in the Yongyeanchun discharges for 17 hours during the hgh tide, then undlscharged for 11 hours during the low tide.

      • 광대역 전달소음저감을 위한 압전지능패널

        이중근,박우철,이현창,정달도 三陟大學校 2001 論文集 Vol.34 No.1

        In this paper, the transmitted noise reduction of piezoelectric smart panels is experimentally studied. The proposed piezoelectric smart panels are comprised of plate structure on which piezoelectric sensor/actuators are bonded and sound absorbing material and/or gap are provided. It is a combination of passive and active approaches utilizing a passive effect at high frequencies and active effect at low frequencies. To prove the concept of piezoelectric smart panels, and acoustic measurement experiment is performed. An acoustic tunnel is designed and its acoustic characteristics are tested. Below 800㎐, the tunnel exhibits a plane wave guide characteristics. When an absorbing material is bonded on a single plate, a remarkable transmitted noise reduction in mid frequency range is observed except the first resonance frequency. By enabling the active control of smart single panel, much noise reduction is achieved at the resonance frequencies. The smart double panel has more potential to reduction the transmitted noise in wide range frequency. Piezoelectric smart panels incorporating passive absorbing material and active piezoelectric devices is a promising technology for noise reduction in a wide range frequency.

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