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이규보,배선근,손상균,이재태,이건수,이경혜,서장수 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1
1. 목적 급성백혈병의 화학요법에 있어서 관해유도 요법시에 보다 더 강력한 항암화학요법을 시행하고 골수억제의 회복을 위하여 말초혈액에서 채취한 조혈모세포의 투여로 그 효과를 증대시키고자 시도하였다. 2. 방법 관해유도 화학요법후에 골수억제시기로부터 회복단계로서 백혈구감소증이 호전도면서 단핵세포가 증가될 때에 말초혈액에서 조혈간세포(stem cell)로 인정되고 있는 CD34+세포의 함유량이 1% 이상되는 시기를 찾아내고 그 때부터 평균 4차례의 단핵구를 분리채집을 하여 -74。C에 냉동보관하였다가 제2차 화학요법후에 해동시켜서 정맥주입하였다. 3. 결과 대상 급성백혈병환자는 6명에 23회의 조혈간세포를 함유한 단핵구 채집을 시행하였고 유효한 단핵구의 채집은 4례에서 가능하였고 2례에서는 유효한 채집이 못되었다. 채집효율은 39.0-74.5%로서 평균 49.8%였다. 채집 후에 혈액학적 변화는 혈색소의 약간 감소 (평균 1.34g/dl)와 혈소판의 감소 (평균20.25%)를 나타내었다. 해동 단핵구를 투여할시에 일과성인 불쾌감, 기침, 흉부압박감, 호흡곤란 등이 있었다. 4. 결론 자가골수이식에서 자기말초혈액조혈간세포이식으로 관심이 이행되는 현시점에 자가조혈간세포를 채집하여 수혈하는 기술이 확립되는 기초를 이루었다고 본다. 이번 대상들은 재발된 금성백혈병들에 시행하였으나, 향후에는 초발시에 제일차 관해유도 화학요법 과정에 시도해야할 것으로 생각한다. Object: Peripheral blood stem cells(PBSC) were collected after remission induction chemotherapy and reinfused after intensified chemotherapy in order to increase the chemotherapeutic efficacy. Method: Collection of mononuclear cells (MNC) was started when CD34+ cells above 1% and WBC above 1,000/ul with mononuclear cell percentage above 30%, the collection procedures were done 2-6 time in each patient of total 6 cases. The collected MNCs were stored in - 750C and reinfused after thawing in the water bath at 370C Results: Twenty three collection procedures from the 6 cases of acute leukemia had made effective MNC collection in 4 cases and mean collection efficiency was 49.8%(from 39.0% to 74.5%). Hematological changes after the procedure were mean reduction of hemoglobin 1.34g/dl and mean 20.25% of decreased platelet count. There were noticed transient symptoms of discomfort, coughing, chest tightness and dyspnea in association with the infusion of stored cells. Conclusion: The basic process for the peripheral blood stem cell transplantation (PBSCT) was accomplished with this supportive care for the consolidation chemotherapy of acute leukemia. Effective PBSCT would be warrented with more qualified process and high does chemotherapy. (Korean J Blood Transfus 6(2) : 41~47,1995)
개에 발생한 만성 승모판폐쇄부전증에 대한 Pimobendan 치료 1례
장재임,전형규,최호정,이영원,송근호 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2006 動物醫科學硏究誌 Vol.14 No.-
A 11-year-old intact male maltese dog with respiratory distress, cyanosis and coughing was referred to the Veterinary Medical Teaching Hospital of Chungnam National University. Loud holosystolic murmur with a palpable precordial thrill was heard at the left apex region by auscultation. Left sided cardiac enlargement and mitral regurgitated flow were detected by thoracic radiography and echocardiography, respectively. Clinical signs were improved by treatment of diuretics, ACE inhibitor and pimobendan.
2차 통계량을 이용한 도래 방향 추정 알고리즘의 성능평가
이민혁,노현민,정대훈,장은영,변건식 東亞大學校附設情報技術硏究所 2005 情報技術硏究所論文誌 Vol.12 No.2
it is needed high quality and big capacity according to fast supply of mobile communication medium. Therefore, adaptive array antenna is actively studied to supply demand. DOA(Direction of Arrival) estimation is important position in adaptive array antenna. The purpose of this paper is to estimate DOA. and compare with the existing algorithm.
이장근,심운택,오장균 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2
To investigate epidemiologic characteristics of traffic accident incidence, the author analyzed randomezed sampled 541 accident victims for 1 year from Jan. 1990 and Dec. 1990. The results were as follows: 1. Kind of vehicles were sedan(53.6%), truck(17.4%), microbus(14.4%), bus(9.1%) and autobicycle (5.5%) in decending order. 2. The proportion of TA ownes to disobey of safety duty was high among the groups of age forties, middle school educated, 4-5yrs carrier, in spring, on monday, at 12-19 hours time, at domestic area, truck, car to others, snowy or rainy weather, at cross road and at curve road. 3. The proportion of TA ownes to over speed was high among the groups of age forties, elementary school educated, 6-10yrs carrier, in summer, on sunday, at 04- 11 hours time, at agricultural area, microbus, car to man, cloudy weather, at cross way and at straight road. 4. The proportion of TA ownes to drinking was high among the groups of age thirties, high school educated, 6-l0hrs carrier, in winter, on saturday, at 20-03 hours time, at agricultural area, microbus, car to car, cloudy weather, at cross walk way & at curve road. 5. Head trauma & multiple organ injuries were high in drnking induced TA & fracture was high in the groups of disobey of safety walking. 6. Head trauma, multiple organ injuries & fracture were high in the group of over speed 60km/hr more over. 7. Head trauma & fracture were high in the group of bicycle rider & multiple organ injuries was high in the group of autobyicycle rider. 8. Average treatment periods was signigicantly long among the group of drinking or overspeed induced TA & autobyicycle rider.
Si Bulk Micromachining을 위한 Wafer Rolling Etching 및 그 특성
김건년,이보나,박효덕,신상모,공경준,장동근,김병철,권혁채,이봉희 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1
A wafer rolling etching system for the silicon bulk micromachining has been designed and fabricated. The silicon diaphragms were anisotropically etched in a 24.5 weight percent KOH solution. Compared to the conventional KOH etching systems, pyramidal hillocks, and wave-shaped structures on the etched surfaces were greatly reduced by using this system. After etching for time of 438 minutes, the average etched depth and the etch-rate were measured to be 537μm and 1.22μm/min, respectively. The average etching uniformity of etching depth was 0.87% in 5-inch wafer. Our results showed that the wafer rolling method enhanced etch uniformity and etch rate.
신건철,이재장,전호석,조성백 江原大學校 産業技術硏究所 1990 産業技術硏究 Vol.10 No.-
The samples used for this work were low grade clay(Fe?O? : 2.90%, TiO? :1.65%) produced from Youngsan-do district, and for the iron-bearing impurities removal having a bad influence on Kaoline sample was carried out column floatation using Oleic acid, Potassium oleat, Aero 840 promotor, Aero 870 promotor and Keroseneas collectors. For removal of the iron-vearing impurities from the kaoline, investigated first chemical composition size distribution of Kaoline sample, also performanced a basic study on pulp density, collector and pH change on a sort frother. The flotation separation of impurities from kaoline can be achieved by using both oleic acid and Aero 840 promotor as collectors within narrow aoid limits(pH 2-3). Pine oil was more effective frother than MIBC with olelic acid as aa collector.
이동 통신 시스템 설계에서 전역 최적화 알고리즘의 성능해석
오정근,장은영,이성신,변건식 동아대학교 정보기술연구소 2003 情報技術硏究所論文誌 Vol.10 No.2
In the design of mobile wireless communication system, Base station location is one of the most important parameters. Designing base station location, the cost of equipment makes low by combining various, complex parameters. We can solve this problem by combining optimization algorithm, such as Simulated Annealing, Tabu Search, Genetic Algorithm, Random Walk Algorithm that have been used extensively for global optimization. This paper shows the 4 kinds of algorithm to be applied to the base station location optimization of mobile communication system and then compares, analyzes the results and shows optimization process of algorithm.