스포츠 활동 참여가 생산직 근로자의 직무만족에 미치는 영향

노형철,정용준,윤오남,박형태,김승동 조선대학교 스포츠과학연구소 2000 스포츠科學硏究 Vol.11 No.-

The purpose of this study was to examine effects of Sport activity Participation of Production Laborers on Job Satisfaction. 380 subjects who had lived in five major cities answered questionnaires. The results were as follows. 1. In proportion of participants to non-participants in sport and leasure activities, the proportion of participants was higher. The most frequently replied answer to the question that how many years have you participated in sport and leasure activities was 3 years. The highest frequency in participation during week-days was 2 3 times. 2. In comparison of personal characteristics of the labores with proportion of participation in sport and leasure activities, sex and marital status were significantly related to participation in the activities. Proportion of continuous participation in sports and leasure activities was higher in males while proportion of participation in the acti vities was higher in females than in males. Age, formal schooling, monthly income and types of job were not significantly related to participation in sport and leasure activities. 3. In comparison of personal characteristics of the labores with job satisfaction, job satisfaction was higher in participants in sport and leasure activities than in non-participants.

기저질환이 없는 사람에서 발생한 Campylobacter fetus에 의한 재발성 심내막염 1예

전재범,정진원,김성혜,송문희,오형철,안성기,최상호,김남중,김양수,우준희,류지소 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

C. fetus 심내막염은 드물게 발생하는 질환으로 주로 면역능이 저하된 환자에서 발병하고 대동맥판을 침범하는 경우가 많으며 적절한 치료가 되지 않을 경우 치사율이 높다. 저자들은 기저질환이 없던 69세 남자에서 C. fetus 심내막염을 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 발열로 내원하여 시행한 혈액배양 검사상 C. fetus가 동정되었고 경식도 초음파 검사상 삼첨판에 증식증이 발견되어 심내막염 진단하에 ceftriaxone에 이어 meropenem으로 총 4주간 항생제를 투여받고 호전되었다가 한달 후 다시 재발하였고 판막부전 소견 진행하여 삼첨판 치환술을 시행받고 전신상태 호전되어 퇴원하였다. Campylobacter fetus is a rare cause of endocarditis. To date, only about 30 cases of C. fetus endocarditis have been reported mainly in the elderly with chronic underlying illnesses. Most cases showed tendency to involve aortic valve. This report describes a case of native tricuspid valve infective endocarditis in a 69-year-old man without any underlying disease. Despite adequate antibiotic therapy for 4-weeks, endocarditis recurred and leading to surgical valve replacement.

Low Serum Pancreatic Amylase and Lipase Values Are Simple and Useful Predictors to Diagnose Chronic Pancreatitis

( Hyoung-chul Oh ),( Chang-il Kwon ),( Ihab I. El Hajj ),( Jeffrey J. Easler ),( James Watkins ),( Evan L. Fogel ),( Lee Mchenry ),( Stuart Sherman ),( Michelle K. Zimmerman ),( Glen A. Lehman ) 대한간학회 2017 Gut and Liver Vol.11 No.6

Background/Aims: This study aimed to evaluate the diagnostic role of low serum amylase and lipase values in the detection of chronic pancreatitis. Methods: Patients underwent endoscopic retrograde cholangiopancreatography and were diagnosed with non-calcific chronic pancreatitis (NCCP; n=99) and calcific chronic pancreatitis (CCP; n=112). Patient serum amylase and lipase values were compared with those of healthy controls (H; n=170). Results: The median serum amylase (normal range, 19 to 86 U/L) and lipase values (7 to 59 U/L) (P25-P75) were 47.0 (39.8 to 55.3) and 25.0 (18.0 to 35.0) for H, 34.0 (24.5 to 49.0) and 19.0 (9.0 to 30.0) for NCCP, and 30.0 (20.0 to 40.8) and 10.0 (3.0 to 19.0) for CCP, respectively. The cutoff values with the highest diagnostic accuracy for discriminating NCCP from H were 40 U/L for amylase and 20 U/L for lipase, respectively, and for CCP from H were 38 U/L for amylase and 15 U/L for lipase, respectively. For the diagnosis of NCCP with a criterion of serum amylase <40 and lipase <20 U/L, the sensitivity, specificity, positive predictive value, and negative predictive values were 37.4%, 88.8%, 66.1%, and 70.9%, respectively. Conclusions: Serum amylase and/or lipase levels below the normal serum range are highly specific for chronic pancreatitis patients. Clinicians should not ignore low serum pancreatic enzyme values. (Gut Liver 2017;11:878-883)

Current concerns on journal article with preprint: Korean Journal of Internal Medicine perspectives

Hyoung-Chul Oh,강현 대한내과학회 2023 The Korean Journal of Internal Medicine Vol.38 No.3

Preprints are preliminary research reports that have not yet been peer-reviewed. They have been widely adopted to promote the timely dissemination of research across many scientific fields. In August 1991, Paul Ginsparg launched an electronic bulletin board intended to serve a few hundred colleagues working in a subfield of theoretical high-energy physics, thus launching arXiv, the first and largest preprint platform. Additional preprint servers have since been implemented in different academic fields, such as BioRxiv (2013, Biology; www.biorxiv.org) and medRxiv (2019, Health Science; www.medrxiv.org). While preprint availability has made valuable research resources accessible to the general public, thus bridging the gap between academic and non-academic audiences, it has also facilitated the spread of unsupported conclusions through various media channels. Issues surrounding the preprint policies of a journal must be addressed, ultimately, by editors and include the acceptance of preprint manuscripts, allowing the citation of preprints, maintaining a double-blind peer review process, changes to the preprint’s content and authors’ list, scoop priorities, commenting on preprints, and preventing the influence of social media. Editors must be able to deal with these issues adequately, to maintain the scientific integrity of their journal. In this review, the history, current status, and strengths and weaknesses of preprints as well as ongoing concerns regarding journal articles with preprints are discussed. An optimal approach to preprints is suggested for editorial board members, authors, and researchers.

Diagnostic accuracy of 22/25-gauge core needle in endoscopic ultrasound-guided sampling: systematic review and meta-analysis

( Hyoung-chul Oh ),( Hyun Kang ),( Jae Young Lee ),( Geun Joo Choi ),( Jung Sik Choi ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.6

Background/Aims: To compare the diagnostic accuracy of endoscopic ultrasound- guided core needle aspiration with that of standard fine-needle aspiration by systematic review and meta-analysis. Methods: Studies using 22/25-gauge core needles, irrespective of comparison with standard fine needles, were comprehensively reviewed. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), and summary receiver operating characteristic curves for the diagnosis of malignancy were used to estimate the overall diagnostic effi ciency. Results: The pooled sensitivity, specificity, and DOR of the core needle for the diagnosis of malignancy were 0.88 (95% confidence interval [CI], 0.84 to 0.90), 0.99 (95% CI, 0.96 to 1), and 167.37 (95% CI, 65.77 to 425.91), respectively. The pooled sensitivity, specificity, and DOR of the standard needle were 0.84 (95% CI, 0.79 to 0.88), 1 (95% CI, 0.97 to 1), and 130.14 (95% CI, 34.00 to 495.35), respectively. The area under the curve of core and standard needle in the diagnosis of malignancy was 0.974 and 0.955, respectively. The core and standard needle were comparable in terms of pancreatic malignancy diagnosis. There was no significant difference in procurement of optimal histologic cores between core and standard needles (risk ratio [RR], 0.545; 95% CI, 0.187 to 1.589). The number of needle passes for diagnosis was significantly lower with the core needle (standardized mean difference, .0.72; 95% CI, .1.02 to .0.41). There were no significant differences in overall complications (RR, 1.26; 95% CI, 0.34 to 4.62) and technical failure (RR, 5.07; 95% CI, 0.68 to 37.64). Conclusions: Core and standard needles were comparable in terms of diagnostic accuracy, technical performance, and safety profile.

Effect of calcineurin inhibitor on post-endoscopic retrograde cholangiopancreatography pancreatitis in patients with liver transplantation: a propensitymatched cohort study

Hyoung-Chul Oh,Jeffrey J. Easler,Ihab I. El Hajj,James Watkins,Evan L. Fogel,Lee McHenry,Stuart Sherman,Hyun Kang,Glen A. Lehman 대한내과학회 2020 The Korean Journal of Internal Medicine Vol.35 No.6

Background/Aims: A calcineurin inhibitor may alter pancreatic function and inflammatory reaction. This study aimed to determine the possible pharmacologic effect of the calcineurin inhibitor, tacrolimus, on pancreatic function, and to determine its preventive effect on post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in liver transplantation (LT) patients. Methods: The serum amylase and lipase values before and after LT were compared. The frequency of post-ERCP pancreatitis was compared between non-LT and LT patients, using propensity score matching method. Results: Median serum amylase values (normal range, 19 to 86 U/L) were 49.0 U/L (38.0 to 68.0) before LT and 27.0 U/L (19.3 to 36.8) after LT, and median serum lipase values (normal range, 7 to 59 U/L) were 40.0 U/L (26.5 to 54.0) before LT and 10.5 U/L (6.0 to 21.0) after LT. Both serum amylase and lipase values significantly decreased after LT (p < 0.001), and to a level comparable to chronic pancreatitis. There was a marginal significant difference between the non-LT and LT groups before the propensity score matching with respect to frequency of post-ERCP pancreatitis (16 [3.2%] in non-LT group vs. 2 [0.9%] in LT group, p = 0.069). After propensity score matching, a marginal significant difference still existed with respect to frequency of post-ERCP pancreatitis (7 [4.8%] in non-LT group vs. 1 [0.7%] in LT group, p = 0.067). Conclusions: The immunosuppression with calcineurin inhibitor may reduce not only the pancreatic enzyme dynamics but also inciting inflammatory event including post-ERCP pancreatitis.

Percutaneous Transhepatic Cholangioscopy in Bilioenteric Anastomosis Stricture

Hyoung-Chul Oh 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.6

Bilioenteric anastomosis strictures are a serious complication of biliary surgery, and often result in recurrent cholangitis, choledocholithiasis,biliary cirrhosis, and hepatic failure. Bilioenteric reconstructive surgery is the standard treatment of choice for such complications. However, percutaneous transhepatic cholangioscopy (PTCS), also known as per-oral endoscopic-guided intervention, is a less invasiveprocedure that is becoming an increasingly popular alternative. This review describes the PTCS procedure (including the preparationprocess), as well as the diagnostic and therapeutic role of PTCS in bilioenteric anastomosis strictures.

Comparison between Right-and Left-sided Stage Ⅲ Colon Cancer: What is Different?

Hyoung-Chul Park,Min Jeong Kim,Bong Hwa Lee,Jae Hwan Oh,Sung-Bum Kang,Seung Chul Heo,Ji Won Park,Seung-Yong Jeong,Kyu Joo Park 대한종양외과학회 2014 대한임상종양학회 학술대회지 Vol.2014 No.3

Plenary Session : EUS-Guided Ethanol Lavage With Paclitaxel Injection For Cystic Tumors Of The Pancreas

( Hyoung Chul Oh ),( Dong Wan Seo ),( Sang Soo Lee ),( Sung Koo Lee ),( Myung Hwan Kim ) 대한소화기학회 2007 SIDDS Vol.9 No.-

Background/Aims: Cystic tumors of the pancreas are frequently detected, and encompass a wide pathologic spectrum ranging from benign to malignant. A substantial proportion of cystic tumors cannot be histologically classified even after extensive diagnostic evaluation, and therefore ultimately require surgical resection. Recently, a pilot study of EUS-guided ethanol lavage reported that complete resolution was achieved in only one-third of patients. Therefore, more effective treatment modalities or ablation agents are required to improve treatment responses. The present study evaluated safety, feasibility and response following EUS-guided ethanol lavage with paclitaxel injection (EUS-EP) for treating cystic tumors of the pancreas. Methods: Eighteen patients were enrolled. The following indications were used 1) urri- or oligolocular tumors, 2) indeterminate cystic tumors for which EUS-guided fine needle aspiration was required, and 3) cystic tumors that increased in size during the observation period. Under EUS-guidance, cyst fluid aspiration, ethanol lavage and injection of paclitaxel were performed. Using CT images, the cystic tumor volume was calculated based on computer estimations of the areas on each axial image and the slice thickness. Response is defined as follows, 1) complete resolution: <5% of original volume (OV), 2) partial resolution: 5 to 25% of OV, 3) Persistent cyst: >25% of OV. Results: The median diameter and volume of cystic tumors were 26.0 mm (17~52 mm) and 3.5 mL (1.2~67.7 mL), respectively. The presumed diagnoses were 3 MCNs, 4 SCAs, 3 peripancreatic lymphangioma, and 8 indeterminate cysts. The median follow-up was 9 months (6~23 months). Complete resolution was observed in 13 patients, partial resolution in 4 patients, and a cyst persisted in one patient. One patient developed mild pancreatitis with abdominal pain one patient complained of vague abdominal pain lasting for 1 month. Conclusions: EUS-EP appears to be a safe, feasible and effective method for treating cystic tumors of the pancreas. Further studies involving larger populations and longer follow-ups are warranted.

Post-ERCP Bleeding in the Era of Multiple Antiplatelet Agents

Hyoung-Chul Oh,Ihab I. El Hajj,Jeffrey J. Easler,James Watkins,Evan L. Fogel,Lee McHenry,Glen A. Lehman,Jung Sik Choi,Hyun Kang,Stuart Sherman 거트앤리버 소화기연관학회협의회 2018 Gut and Liver Vol.12 No.2

Background/Aims: This study aimed to determine the risk of post-endoscopic retrograde cholangiopancreatography (post-ERCP) bleeding among patients taking antiplatelet agents (APAs), particularly in the era of multiple APAs. Methods: The primary outcomes were the frequency, type, and severity of ERCP-related bleeding according to the use of APAs. Results: The frequencies of post-ERCP bleeding among the four different groups were 16 of 2,083 (0.8%) in the no drug group, 12 of 256 (4.7%) in the aspirin group, 3 of 48 (6.3%) in the single APA group, and 4 of 48 (8.3%) in the multiple APA group (p<0.001). In the univariate analysis, post-ERCP bleeding was associated with age, pull-type sphincterotomy, and APA and was inversely associated with balloon dilation of the biliary orifice. In the multivariate analysis, pull-type sphincterotomy (odds ratio [OR], 7.829; 95% confidence interval [CI], 1.411 to 43.453; p=0.019) and country (Korea: OR, 0.124; 95% CI, 0.042 to 0.361; p<0.001) were associated with post-ERCP bleeding. Conclusions: The frequency of post-ERCP bleeding was statistically higher in patients on any APA within 6 days prior to ERCP. However, in the multivariate analysis, APA use was not associated with post-ERCP bleeding. Until a large, adequately powered study to detect differences is performed, caution is recommended when considering invasive procedures during ERCP in patients on APAs.