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      • 대학생의 뇨pH와 정서성 및 식품기호도에 관한 연구

        최운정,황혜선 서강정보대학 1989 論文集 Vol.8 No.-

        This study attempted to investigate the relationships between the urinary pH, emotional state and food preference. The subjects were 55 college students living in Kwang- ju. In this study, the emotional state and food preference of the subjects were investigated through questionnaires. Also, the urinary pH of the subjects were obtained by examination. The results are summarized as follows; 1) The height and weight of the subjects were those of Korean standards for man and woman. Their uninary pH, Hb and Hct concentrations were in normal range. 2) The mean hedonic score for food preference in subjects was 2.8. The difference in food preference between male and female was not significant except for a soy bean item and protein food group that were more favored by male. The subjects favored grapes, tomatoes, cucumber, apple, strawberry in order. 3) The subjects were classified into three groups, a little acid group, neutral group and a little alkali group accoring to thein urinary pH. A little acid group answered significant high rate to the items of the emotional state, "hard to study" and "no self-confidence". 4) Foods that have significant difference between the urinary pH and food preference were sweet potatoes, bread and yoghurt but not consistent according to the urinary pH. 5) The food preference according to the emotional state showed significant difference in cereal group. "Not to talk with other" group showed low rate preference to cereal group. From the results above the relationship between the emotional stability and the urinary pH was found. On the other side, many cooking methods should be studied and nutrition oducation should be oriented to recommend an increased in take of fat & oil group, milk group and vegetable group.

      • KCI등재후보

        의류 중의 미생물에 대한 소비자의 지식과 세탁습관 실태조사 분석

        최해운,정찬진,박명자 服飾文化學會 2002 服飾文化硏究 Vol.10 No.6

        Microorganisms living in clothing cause damage to fabric as well as unhygienic conditions with unpleasant odor for wearers. Removal or growth of microorganisms are affected by the conditions during washing and storage. The purpose of this research was to study the consumer's knowledge and habits in laundering with respect to microorganisms in clothing. For survey method, questionnaires were administered to 580 housewives, age of 20~60s living in Seoul. Employing 479 respondents, the data were analyzed by using deseriptive statistics. The results are as follows; The level of knowledge about microorganisms of clothing was high in general, but wasn't expert level. Many people had experienced damages of textiles, clothing and unpleasant odor due to microorganisms. Fabric softeners and bleaches were rarely used for disinfection but usually used for antistatic. whitening or removal of stains. There was no relationship between laundering habits the knowledge of microorganism, and experience of clothing damage by microorganism

      • 하이브리지 산업에서 SPC 와 EPC통합모형의 사례연구

        김종걸,정해운 한국경영과학회 2002 한국경영과학회 학술대회논문집 Vol.- No.1(2)

        SPC와 EPC의 통합은 연속공정산업에서 성공적으로 사용되고 있다고 널리 인식되어 있다. 그러나, 이산적인 부품 제조공정의 모니터링과 연속 생산공정 모니터링 양쪽 모두를 포함하는 하이브리드(hybrid) 산업에서의 이들 기법을 적용하기 위해서는 샘플링비율, 고장감지, 실시간 보정과 공정통제 등에 관한 연구가 필요하다. 본 연구에서는 SPC와 EPC의 차이를 비교분석하고, 하이브리드 산업에서 SPC와 EPC를 성공적으로 통합하여 제품공정품질관리에 적용하는 사례연구를 제시하고자 한다.

      • 마산연안지역의 국지풍 순환 및 대기오염물질 확산에 관한 연구

        김유근,이화운,문윤섭,김해동,원경미,정우식,오인보 부산대학교 환경문제연구소 1997 環境硏究報 Vol.15 No.1

        To investigate a horizontal windrose and the mixing height in Masan coastal area, a local atmospheric flow and the concentration of air pollutants were analyzed by abserved data from AWS, airsonde and air sampler. The land-sea breeze model and the ISCST2 model of U. S. EPA(Environmental Protection Agency) were used to predict the concentration of air pollutants such as SO2 and TSP. As a result, during spring the principal wind direction in the Masan region is mainly represented by windrose of the WNW and NW, which can be induced by land breeze and the SE and SSW of sea breeze even if weak wind speed. The mixing height during the measurement was marked with the range from 400 m(0900 LST) to 1450 m(1500 LST), and the height of an inverse layer was presented as the range from 30 m(2100 LST) to 150 m(0300 LST). It is very important to cosider the local wind field for the accurate diffusion and movement of air pollutants in coastal urban area. The atmospheric flow was simulated by the two-dimensional local wind model upon considering the orographic characteristics such as land-sea contrast, mountain valley and urban building. The result of air quality simulated by ISCST2 support that the dispersion pattern of the pollutants in that area was followed as local circulation system in coastal urban area.

      • 두개강내 출혈을 동반한 불응성 특발성 혈소판감소성 자반증의 CYCLOPHOSPHAMIDE 치험 1예

        서정철,양태영,최연수,박유환,김완중,허경,정원영,정춘해 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

        Idiopathic thrombocytopenic purpura(ITP) is an autoimmune bleeding disorder characterized by the development of antibodies to one's own platelets, which are then destroyed by phagocytosis in the spleen and liver. Its clinical manifestations are characterized by bleeding and the most serious complication is hemorrhage into the central nervous system, but which is rarely seen below 1%. In treating IPT, the therapy of first chice is administration of adrenocorticosteroid and r-globuline. If satisfactory results are not obtained, then splenectomy is recommended. If this also proves inadequate, then administration of immunosuppressants is carried out. 16-year-old male was admitted with complaints of left hemiplegia and nasal bleeding. This case may be developed spontaneous intracerebral hemorrhage causing thrombocytopenia and was treated by steroid, r-globuline and splenectomy, but satisfactory results are not obtained. After all, the paient was successfully treated with cyclophosphamide.

      • Medicinal Chemistry : Original Article ; Hexane Extract of Orthosiphon stamineus Induces Insulin Expression and Prevents Glucotoxicity in INS-1 Cells

        ( Hae Jung Lee ),( Yoon Jung Choi ),( So Young Park ),( Jong Yeon Kim ),( Kyu Chang Won ),( Jong Keun Son ),( Yong Woon Kim ) 영남대학교 약품개발연구소 2015 영남대학교 약품개발연구소 연구업적집 Vol.25 No.-

        Background: Hyperglycemia, a characteristic feature of diabetes, induces glucotoxicity in pancreatic B-cells, resulting in further impairment of insulin secretion and worsening glycemic control. Thus, preservation of insulin secretory capacity is essential for the management of type-2 diabetes, In this stud, we evaluated the ability if an Onrthosiphon stamineus(OS) extract to preventglucotoxicity in insulin-producing cells We measured inulin mRNA expression and glucose-stimulated insulin secretion (GSIS)in OS treated INS-1 cells after exposure to a high glucose(HG;30mM)concentration. The hexane extract of OS elevated mRNAexpression of insulin as well as pancreatic and duodenal homeobox-1 of INS-I cells in a dose-dependent manner, The hexane OS extract also increased the levels if phosphatidylinositol 3-kinase(PI3K) in a concentration- dependent manner. Additionally, Akt phosphorylation was elevated by treatment with 100and 200 umol of the hexane OS extract. Three days of HG exposure suppressed insulin mRNA expression and GSIS;these expressions were restored by treatment with the hexane OS extract.HGelevated peroxide levels in the INS-1 cells. These levels were unaffected by OS treatment under both normal and a hypreglycemic conditions. OUR results suggested that the hexane extract of OS elevates insulin mRNA expression and prevernt glucotoxicity induced by a-3day treatment with HG, this was associated with the actication of PI-3K and Akt.

      • KCI우수등재

        Handgrip Strength Is Associated with Metabolic Syndrome and Insulin Resistance in Children and Adolescents: Analysis of Korea National Health and Nutrition Examination Survey 2014–2018

        Hae Woon Jung,이지은,Jaehyun Kim 대한비만학회 2022 Journal of obesity & metabolic syndrome Vol.31 No.4

        Background: Reduced handgrip strength (HGS) is associated with adverse cardiometabolic health outcomes. We examined HGS, metabolic syndrome (MetS), and insulin resistance (IR) in children and adolescents. Methods: The following population-based data from 2,797 participants (aged 10–18 years) of the Korea National Health and Nutrition Examination Survey 2014–2018 were analyzed: complete anthropometric measures, HGS, MetS, and IR (subgroup with fasting insulin, n=555). HGS was analyzed as the combined HGS (CHGS) and the normalized CHGS (nCHGS=CHGS divided by body weight). Results: At a mean age of 14.4 years, 276 participants (9.9%) had abdominal obesity, 56 (2.0%) had MetS, and 118 (20.9%) had IR. Individual components of MetS and IR were inversely associated with the nCHGS. The odds ratios (ORs) for MetS and IR decreased significantly with higher nCHGS after adjustment for sex, age, physical activity, and sedentary times. The optimal cut-off values that predicted MetS were 0.80 kg/kg (males) and 0.71 kg/kg (females), with significant associations with MetS (OR: 7.4 in males; 5.7 in females) and IR (OR: 3.3 in males; 3.2 in females) observed when nCHGS values were lower than those cut-offs. Conclusion: HGS is associated with MetS and IR and might be a useful indicator of cardiometabolic risk factors in children and adolescents.

      • Primary cutaneous adenoid cystic carcinoma of the chest wall

        ( Ji Hae An ),( Go Woon Choi ),( Seung Hui Seok ),( Seon Gu Lee ),( Jung U Shin ),( Hyun Jung Kim ),( Hee Jung Lee ),( Dong Hyun Kim ),( Moon Soo Yoon ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

        Adenoid cystic carcinoma (ACC) is a malignant neoplasm of glands which commonly occurs in salivary glands. Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare form of ACC that primarily presents on the skin. A diagnosis of a primary tumor arising in the skin can be made only after excluding metastatic deposits from other, more common sites. PCACC tends to infiltrate and recur locally but rarely metastasizes to distant organs and lymph nodes. A 62-year-old female presented with a 1-year history of an asymptomatic erythematous indurated plaque on her anterior chest wall. Biopsy finding revealed an intradermal tumor without an overlying epidermal connection. The tumor was composed of islands of basaloid cells arranged in cribriform pattern with areas showing cystic degeneration. Cystic spaces contained abundant basophilic mucin. Perineural invasion was conspicuous. Immunohistochemical analysis revealed positivity for c-kit staining and epithelial membrane antigen (EMA) staining in focal luminal area. The lesion was diagnosed as ACC. Final diagnosis of PCACC was made after excluding the possibility of metastasis from other primary lesion by imaging studies. The patient has been followed up for 6 months with no evidence of recurrence of metastasis after total excision of the lesion. We herein report a case of PCACC of the chest wall to raise awareness of this rare tumor with review of literature.

      • A case of concurrent lichen planus and vitiligo in a patient undergoing nivolumab treatment for metastatic melanoma

        ( Ji Hae An ),( Go Woon Choi ),( Seung Hui Seok ),( Seon Gu Lee ),( Jung U Shin ),( Hyun Jung Kim ),( Hee Jung Lee ),( Moon Soo Yoon ),( Dong Hyun Kim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

        Nivolumab is a programmed cell death-1 receptor (PD-1) inhibitor. Although proven to be effective for oncologic treatment by activating T-cell response to cancer cell, unchecked stimulation has potential for immune-related adverse effects. Cutaneous adverse events have been reported in up to 50% of patients. The most common adverse cutaneous events include rash, pruritus, and vitiligo. In addition, lichenoid, psoriasiform eruptions and rarely lichen planus have been reported. A 64-year-old female presented with a 2-month history of pruritic rash and hypopigmented eruption on her extremities. The patient was diagnosed with metastatic melanoma 3 years ago and has been treated with nivolumab for 10 months. By her 14th treatment of nivolumab, the patient developed rash on her extremities. The biopsy specimen revealed hyperkeratosis, wedge-shaped hypergranulosis, saw-tooth like acanthosis, and band-like lymphohistiocytic inflammation in papillary dermis. The histologic findings were consistent with lichen planus. Examination under Wood's lamp for the hypopigmented eruption confirmed depigmentation. The patient improved with systemic and topical steroid, and has remained on nivolumab therapy. We herein report a case of concurrent lichen planus and vitiligo in a patient undergoing nivolumab treatment for metastatic melanoma, which highlights the need to be aware that immune-related adverse cutaneous events among patients on anti-PD-1 therapy.

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