심혈관계 질환으로 관상질환 집중치료실에 입원한 환자들의 혜후 측정을 위한 APACHEⅢ점수 체계의 임상적 유용성

이공섭,이창선,최현주,홍종서,강지향,김도형,이민영,오인균,김병엽,김상억,김학찬,한승혜,이재용,지영우,안경주 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

Compass 연산자를 이용한 Edge의 방향정보 표현

이병일,최현주,최흥국,전순미 인제대학교 1998 仁濟論叢 Vol.14 No.1

에지(edge)의 검출은 영상처리를 하기 위한 전처리 단계로서 중요하고도 기초가 되는 부분이다. Compass 기울기 연산자는 방향에 따른 마스크를 사용하여 에지를 검출하여 주는데, 본 논문에서는 이러한 Compass 기울기 연산자를 이용하여 찾아지는 에지를 방향에 따라서 색상을 지정하여 표현함으로써 에지 정보의 방향성을 시 각화하도록 하였다. 예제 이미지는 임의의 타원으로 구성된 실험용 이미지와 다른 하나는 쥐와 운동 신경조직을 현미경으로 확대하여 본 이미지이다. Digital Image Processing is divided into two branches. One is Improvement of Image Information which helps human beings to understand image, and another is Image Data Analysis which helps the machine to have cognizance of image. Edge Detection is indispensable part to apply two branches, for it is basic application. Edge Detection is important and basic preprocess at Image Processing. Edge can be found by Compass operator as direction with 3×3 Masks. Compass operator has 8 element to be compared. Each has an information about direction of an edge. To visualize edge information, We propose the method of edge detection as direction showed by color. First, We had experiment on 4-Direction, then on 8-Direction. 8-Direction 8-Color method was better than 4-Direction 4-Color method, for Compass operator had 8 elements. Result Image shows the color which has direction information.

半夏의 修治方法에 따른 細胞毒性硏究

李秀培,金德宗,金康柱,田炳勳,禹元洪 圓光大學校 韓醫學硏究所 1993 원광한의학 Vol.3 No.1

The purpose of this study is to know the effects of Pinelliae Tuber on the cytotoxicity of human gingival fibroblasts according to brewing methods. Pinelliae Tuber was extracted by water in the state of being raw materials, prebrewing with Zingiberis Tuber and alumen. The extracted Pinelliae Tuber was applied to the cultured human gingival fibroblasts. The cytotoxic effct of Pinelliae Tuber was meaeured by MTTassay and microscopic findings. The results were as follows : 1. The cell viability of the fibroblasts by Pinelliae Tuber water extracts significantly decreased compared to control group. 2. The cell viability by the Pinelliae Tuber extracts prebrewed with Zingiberis Tuber was similiar to those of control group. 3. The cell viability by the Pinelliae Tuber extracts prebrewed with alumen slightly decreased, but was higher than those of PT group. 4. According to the microscopec findings, the number of cell count were smaller than normal in all experimental group, specially in the PT group, and showed the shrinkage of cytoplasmic process in the PT group and PA group.

韓國學上의 杜詩

李丙疇 東國大學校 국어국문학부 1962 國語國文學 論文集 Vol.3 No.-

안면 골절의 후유증으로 인한 치아의 맹출장애 및 안모 비대칭 : A possible complication of facial fracture in child

이선재,유기준,송승희,서영진,조갑주,고부일,박영주,안병근 한림대학교의료원 1994 人間科學 Vol.18 No.11

보툴리눔독소 A를 이용한 반복적인 nasal flare의 치료

이상주,김현정,김병대,정원순,이승헌 대한피부과학회 2003 大韓皮膚科學會誌 Vol.41 No.12

Repeated nasal flare is a condition that one repeatedly dilates one's nostrils unconsciously. It is not pathogenic, however, may be a cosmetic problem. This is caused by excessive activities of the alar part of nasalis. We, herein, report a successfully treated case with the botulinum toxin A. (Korean J Dermatol 2003;41(12):1689~1690)

1996년과 1999년 경기지역 초등학교 학생들에서 유행성이하선염에 대한 면역도 조사

나병국,이주영,고운영,이진수,신구철,이주연,최보율,기모란,양병국,강춘,김우주,김지희 대한감염학회 2001 감염 Vol.33 No.3

Background : Although massive use of live attenuated mumps virus vaccines successfully reduced the incidence of mumps virus infection worldwide, mumps outbreaks have not been completely eliminated, even in vaccinated populations. In recent years, the incidence of mumps has been remarkably increased in Korea. This study was designed to evaluate the recent seroprevalence rate of mumps IgG among children in Kyonggi province at 1996 and 1999. Methods : Study population included students from 8 elementary schools in Kyonggi province. Serum samples were collected twice at 1996 and 1999 and tested for mumps-specific antibody by enzyme-linked immunosorbent assay (ELISA). We also conducted a questionnaire survey on the parents and collected the records including history of vaccination and mumps infection. Results : The seropositive rates against mumps were 89.47% and 89.74% at 1996 and 1999, respectively, and they were not significantly different when compared to age, sex, and region. Although the first vaccination rates were 92.17% and 92.25% at 1996 and 1999, respectively, the second vaccination rates were only 37.89% and 38.03% at 1996 and 1999, respectively. Infection rate showed no significant difference between vaccinated groups and nonvaccinated gropus. Seropositive rate of infected group was higher than that of noninfected group but it was not significantly different between the vaccinated and the nonvaccinated. Conclusions : This study showed the seropositive rate and vaccination against mumps in children. There were no significant relationships between vaccination and infection. Therefore, it seems likely that the vaccination is not fully protective against mumps infection. This study will be helpful for the establishment of guideline for prevention and treatment of mumps in Korea. (Korean J Infect Dis 33: 157∼164, 2001)

Propylthiouracil에 의한 중증 급성간염 1예

임종주,심미령,이명수,김태현,오석규,안선호,박무림,김남호,박병현,조성구 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.2

PTU에 의한 간염의 발생은 매우 드물게 발생하는 것으로 알려져 있으나 저자들은 Graves씨 병으로 진단 받고 propylthiouracil 투여를 받고있던 환자에서 중증의 급성 간염이 발생한 1예를 경험하였기에 보고하는 바이다. Propylthiouracil is widely used to treat patients with hyperthyroidism. This drug has been associated with severe hepatotoxicity rarely. We presented the case of jaundice and profound liver dysfunction from a 23-year old woman treated with propylthiouracil for hyperthyroidism. Viral, metabolic, and autoimmune liver disease could be excluded and liver biopsy revealed a pattern of acute hepatitis. After discontinuing the drug, there was a progressive resolution of hepatic symptoms and decrease in biochemical data of the liver. Despite propylthiouracil induced hepatitis in rare case, patients receiving propylthiouracil are exposed to develope severe hepatotoxicity. Therefore it might be advisable to monitor level of the transaminase on regular base from patients receiving propylthiouracil.

급성 충수돌기염의 조기 진단을 위한 초음파검사의 의의

오병연,임경수,이영주,김원,최옥경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background: In the most of emergency department, the diagnosis of appendicitis has been carried by clinical history, physical examination and plain X-ray. But the diagnostic accuracy by these methods was so low that unnecessary operation was common performed, and sometimes the operation was delayed till the physicians could confirm the acute appendicitis clinically. Although many kinds of diagnostic tools such as CT scan, laparoscope, and etc, we believe that ultrasonography(US) would be a quick and sensitive diagnostic method for the evaluation of acute appendicitis in the Emergency Department. Methods: Forty-seven patients who were clinically suspected as acute appendicitis were evaluated with the grayscaled US by emergency physician. The probe of US was placed on maximal tender point of abdomen, and the appendix image was evaluated while probe was pressed deeply and gently. When the blind loop was found at maximal tender point of abdomen, we evaluated the diameter of appendix, the presence of compressibility, peri-appendiceal fluid collection and other mass effect. As soon as the ultrasonographic evidences of the appendicitis were noticed, the operations were done and pathologic report were reviewed later. Results: Among the forty-seven patients, forty patients were diagnosed as a appendicitis by Us, and most common ultrasonic findings were as follows; 1) non-compressible blind loop larger than 5 mm in diameter, 2) wall thickening more than 3 mm, 3) peri-appendiceal fluid collection, 4) periappendiceal mass. Among remaining 7 patients in whom we could not get any positive findings of appendicitis, abdominal CT scan was carried in 2 cases who had direct and rebound tendemess on right lower abdomen, and CT scan showed the evidences of the appendicitis. The other 5 cases without rebound tendemess were observed for 2 hours, and abdominal pain was disappeared lately. Finally forty-two patients were operated and confirmed as acute appendicitis by pathologic reports; 24 were reported as suppurative appendicitis, and 12 cases of gangrenous appendicitis, 3 cases of perforated appendicitis, and 3 cases were peri-appendiceal abscess. The specificity of US in the diagnosis of acute appendicitis was 71.4%, and the sensitivity was 95.2%. Conclusions: In some patients suspected appendicitis, emergency physicians could diagnosis acute appendicitis accurately and rapidly by use of ultrasonography. Although the US was an accurate imaging modality to diagnosis acute appendicitis and evaluate its complications, we recommend a laparotomy or abdominal CT scan in the patients with negative US findings in spite of presence of peritoneal irritation signs such as rebound tenderness and/or muscle guarding on right lower abdomen.

Methylation이 心筋細胞膜에서의 ATP에 의한 Calcium Transport에 미치는 影響

金柱炳,昔廷鎬,李載欣 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

For the purpose of studying the properties of calcium pump, the effect of methy lation on the ATP-induced Ca-transport in the isolated porcine sarcolemmal vesicles which were loaded with high KCI was investigated. 1) Ca-transport by ATP was increased significantly, compared to control sarcolemmal vesicles. 2) Ca-transport of the vesicles preincubated in the methylation medium without PM II was increased by ATP, but less than control sarcolemmal vesicles. 3) Ca-transport of the vesicles preincubated in the methylation medium with PM II was decreased by ATP in the KCl medium, but increased in NaCI medium. But Ca-transport by ATP in the methylated vesicles in the reaction medium (NaCI and KC1) was significantly decreased, compared with Ca-transport by ATP in the nonmethylated vesicles. From the above results, it was suggested that methylation of membrane protein by PM II can change the membrane properties or the activity of calcium ATPase transporting calcium.