정신질환자의 Toxoplama Gondii 항체가 조사

피상순,박현,박민철 圓光大學校 醫科學硏究所 1999 圓光醫科學 Vol.15 No.1

Background: The study was undertaken to evaluate Toxoplasma antibody liters in the patients with chronic schizophrenia (n=100), mood disorder (n=48), alcoholism (n=45), and normal persons (n=100). Method.: indirect fluorescent antibody test and positive and negative symptom scale (PANES) was applied and the tilers of 1:16 or more were regarded as positive. Results: The number and percentage of positive reaction by indirect fluorescent antibody test were as follows; 5 (5%) of 100 chronic achizophrenics, 0 (0%) of 48 mood disorders, 1 (2%) of 45 alcoholics and 1 (1%) of 100 normal persons. Chronic schizophrenics with positive reaction showed negative symptoms and classified undifferentiated type. They used to live in rural area raising domestic animals including cats and meat was their favoriate food. Conclusion: Chronic schizophrenic group were more postive reactor than other group. They showed negative symptoms and classified undifferentiated type. But more larger study needed for conclusions.

지각된 스트레스, 역기능적 태도, 자기 효율성, 사회적 지지 및 대처양식이 물질남용 청소년의 부적응에 미치는 영향

피상순,오상우,박민철 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

연구목적: 물질남용 청소년에 대한 물질남용 교육과 치료프로그램의 이론 설정을 위해 취약성-스트레스 모형과 사회학습 모형 중 어느 모형이 물질남용 행동과 우울을 설명하는데 적합한 모형인가를 알아보는데 있다. 방법: 연구대상은 물질남용을 이유로 소년원에 입소한 청소년 158명이었다. 연구도구는 반구조화된 면담 도구와 9개의 자기 보고식 질문지, 즉 지각된 스트레스, 역기능적 태도, 자기효율성, 사회적 지지, 대처양식, 물질 사용 효과에 대한 기대, 양적 물질남용, 물질남용 관련 문제, 우울 측정 질문지였다. 자료 분석은 상관과 중다회귀분석을 이용하였다. 결과: 다음과 같다. 1) 양적 물질남용은 물질남용 관련 문제, 친구의 물질 사용량, 지각된 스트레스, 회피적 대처, 긍정적 기대, 부정적 기대, 자기 효율성 사이에 통계적으로 의미있는 상관이 있었다. 물질남용 관련 문제는 지각된 스트레스, 긍정적 기대, 부정적 기대, 자기 효율성 사이에 높은 상관이 있었다. 또한 지각된 스트레스, 대처양식 및 사회적 지지 사이의 상호작용 효과가 통계적으로 의미 있었다. 2) 양적 물질남용 변량은 취약성-스트레스 모형이 16.9%를 설명하였고, 시회학습 모형은 30.5%를 설명하였다. 물질남용 관련 문제 변량은 취약성-스트레스 모형이 16.6%를 설명하였고, 사회학습 모형은 18.4%를 설명하였다. 결과적으로 종속변인을 물질남용 관련 문제로 했을 때는 두 모형이 비슷하게 설명 되었고, 양적 물질남용으로 했을 때는 사회학습 모형이 취약성-스트레스 모형보다 더 설명력이 있었다. 3) 취약성-스트레스 모형은 우울 변량의 18.8%를 설명하였으나, 사회학습 모형은 4.7%만을 설명 하였다. 결과적으로, 우울을 설명하는 데는 취약성-스트레스 모형이 더 우세한 것으로 나타났다. 결론: 양적 물질남용을 설명하는 데는 사회학습 모형이 취약성-스트레스 모형보다 우세하고, 물질남용 관련 문제는 두 모형이 비슷하며, 우울을 설명하는 데는 취약성-스트레스 모형이 더 우세하였다. Objectives: This study was intended to investigate the influences of the perceived stress, dysfunctional attitude, self-efficacy, social support and coping style on maladaptation in the adolescents with substance abuse. Specifically, two models, vulnerability-stress model and social learning model of substance abuse in adolescents were compared for the power to predict substance abusing behaviors and depression. Methods: To investigate these objects, the semi-structured interview schedule, and scales for the perceived stress, dysfunctional attitude, self-efficacy, social support, coping style, expectation of substance effect, quantity of substance abuse, problems-related substance abuse and BDI were used. One hundred and fifty eight adolescents with substance abuse were asked to reply to them. The data were analyzed by correlation and multiple regression analysis. Results: The results were as follows 1) Among each variables of the adolescents with substance abuse, quantity of substance abuse had significantly high correlation with problems-related substance abuse, quantity of using of substance by friends, perceived stress, avoidant coping, positive expectancy, negative expectancy, self-efficacy. Problems-related substance abuse had significant high positive correlation with perceived stress, positive expectancy, negative expectancy and self-efficacy. Interaction effect of perceived stress, coping style and social support were statistically significant. Main effects of effect of substance abuse were significant. 2)① Vulnerability-stress model predicted 16.6% of variances on problems-related substance abuse and social learning model, 18.4% ② Vulnerability-stress model predicted 16.9% of variances on quantity of substance abuse and social learning model, 30.5% 3) Vulnerability-stress model predicted 18.8% of variances on depression and social learning model, 4.7% Conclusions: The result of this study indicated that vulnerability-stress model was superior in predicting depression and social learning model was superior in predicting quantity of substance abuse. Two models were equal in problems-related substance abuse.

입원된 알콜리즘 환자의 정신병리

피상순,오상우,노승호 大韓神經精神醫學會 1990 신경정신의학 Vol.29 No.3

This study was to investigate the psychopathology of 55 patients with alcohol depende-nce, who had been admitted to Wonkwang University Neuropsychiatric hospital from Octo-ber, 1988 to May, 1989. They were diagnosed with DSM-III-R, who had 5 score or more an Alcoholism Screening Test (AST). The control group was 32 social drinkiers who had less than 5 score on AST. All subject was evaluated with AST., MMPI, SCL-90-R and Hop-kins Psychiatric Rating Scale(HPRS). The results were as follows : 1) The MMPI profile of the patients with alcohol dependence was L-6-8-9 type, and that of social drinkers was S-K-5-2-3 type. 2) On MMPI, the alcoholic group showed significantly higher scores than social drinkers in Pa, Pt, Sc and Ma subscales at the level of 1%, and F, Hs and Pd subscales at the le-vel of 5%. 3) On SCL-90-R, both groups showed 40-55 score with normal of subscales. Specially, alcoholic group showed significantly higher scores on SOM, O-C, DEP, PSY, GSI and PSDI subscal at the level of 1% and ANX and PHOB subscales at the level of 5%. 4) On the HPRS rated by the families, the patients were rated more severs than the so-cial drinkers on all of subscales except 4 subscales. 5) Compared the transformated scores of patients' SCL-90-R to scores of the corre-sponding HPRS subscales rated by their families, the patients rated more severe about themselves on SOM, ANX, PHOB and PSY subscales than their families, but rated lower on HOS subscale. 6) Compared the transformated scores of patients' SCL-90-R to the scores of the corre-sponding HPRS subscales rated by their doctors, the patients rated more severe about the-mselves on ANX, PHOB and PSY subscales. 7) On HPRS rated about the patients, their families rated higher on HYS subscale and lower on SOM and ANX subscales than their doctors.

BDI의 요인분석 : 의학계열 대학생 자료를 중심으로

오상우,피상순,박민철 圓光大學校 醫科大學 神經精神科學敎室 1997 圓光精神醫學 Vol.13 No.1

본 연구는 의학계열 대학생 집단의 BDI 자료를 중심으로 BDI의 요인구조를 알아보고자 하였다. 연구대상자는 심리학(혹은 임상심리학)을 수강하는 305명의 대학생(남자: 142명, 여자: 163명)이었다. BDI의 요인구조를 알아본 결과, 의학계열 대학생 집단의 자료에서는 4개 요인이 추출되었다. 4개 요인의 전체 설명변량은 43.8%이었는데, 제1요인(일반 우울 증상), 제2요인(생리적 증상과 정서증상), 제3요인(정서 증상과 인지 증상) 및 제 4요인(생리적 증상)으로 나타났으며, 요인들의 설명 변량은 각각 25.5%, 6.8%, 6.0% 및 5.5%이었다. 끝으로 본 연구의 의의, 제한점 및 시사점이 논의되었다. This study examined the factor analysis of the BDI in a sample of 305 medical college students. who attended introduction to psychology(or clinical psychology). Four factors in medical college students sample were abstracted from the BDI by factor analysis. Variance of the four factors were 43.8%. And variance of factor 1(general depressive symptoms), factor 2(physiological symptoms & affective symptoms), factor 3(affective symptoms & cognitive symptoms) and factor 4(physiological symptoms) were 25.5%, 6.8%, 6.0%, and 5.5% respectively. Finally, significances, limitions and suggestions of this study were also discussed.

기분장애 환자의 스트레스와 정서반응 : 우울, 불안, 분노 반응

박민철,오상우,류미경,피상순,고정인 대한생물치료정신의학회 1999 생물치료정신의학 Vol.5 No.2

Objectives : This study was investigated to demonstrate the relationship between stress and emotional responses of depression, anxiety, and anger in patients with mood disorder.Methods : Fifty patients with major depressive disorder diagnosed by DSM-IV were compared to those with bipolar manic disorder. All subjects were evaluated for perceived stress, Beck depression inventory, dysfunctional attitude, state-trait anxiety, state-trait anger and anger expression. The data were analyzed by t-test, correlation, and multiple regression analysis.Results : The results were as follows.1. Depressive group had significantly higher score of perceived stressful life events, depression, state anxiety and trait anxiety than manic group.2. Perceived stress in depressive group was positively correlated with depression, anxiety, state and trait anger, anger expression and sex, however that in manic group was positively correlated with state anger and anger expression.3. In depressive group, trait anxiety, trait anger, age, and dysfunctional attitude predicted 70.6% of variance on depression, perceived stress predicted only 1.2%. Trait anxiety predicted 67.6% for state anxiety, and trait anger and trait anxiety predicted 41.5% for state anger, trait anger and sex predicted 34.0% for anger expression.4. In manic group, education and trait anger predicted 28.7% of variance of depression, and trait anger predicted 38.3% for state anxiety. Trait anger and education predicted 29.4% for state anger, and state anger and sex, state anxiety predicted 36.3% for anger expression.Conclusion : The results suggest that emotional responses to perceived stress in depressive group are related to depression, anxiety, and anger but those in manic group are related to anger.

부랑인시설 수용자에 관한 사회정신의학적 연구

김종주,박남진,박민철,오상우,권혁일,박종호,피상순,유성훈,권영숙,박상규,한인순,김금숙,박순천,현윤이 圓光大學校 醫科大學 神經精神科學敎室 1987 圓光精神醫學 Vol.3 No.1