귀지선 종양 증례 1

최을수,제갈준,배보경,최지희,정성목,최해경,김대응,이창우 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3

A 9-year-old male Yorkshire terrior with recurrent chronic otitis externa and otitis interna was referred to the Veterinary Medical Teaching Hospital of Seoul National University. Radiographic findings indicated mineralization around the right ear canal. A tan nodular mass, 1cm in diameter, was noted near the tympanum after total ear canal ablation. Cytologically, the imprint smear of the cut surface of the mass produced clusters of cells with abundant and weakly basophilic cytoplasm, one small round nucleus and one or two nucleoli, mixed with both degenerate and non degenerate neutrophils. The location of the nuclei was eccentric, and some cells contained somewhat coarse black granules in their cytoplasms, on which the mass was diagnosed as ceruminous gland adenoma or hyperplasia associated with inflammation. Histopathologic examination of the tumor was compatible with a diagnosis of ceruminous gland adenoma. The patient is responding well to sugery and antimicrobial treatment.

개에서의 침윤성 지방종

최을수,정성묵,김방현,김채옥,김대용,권오경,이창우 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.4

A 7 year-old male Maltese dog was referred to Seoul National University Veterinary Medical Teaching Hospital with a recurrent mass in the right scapular region. The patient had no pains associated with the mass. On aspiration cytology, the neoplastic mass is composed of clusters of mature adipocytes with large lipid vacuoles, intermixed with frequent microcapillary vessels which is characteristic of lipoma. At surgery, the mass was infiltrated into the surrounding muscles and therefore the complete resection of the mass was difficult. Histologically, the mass was diagnosed as infiltrative lipoma. The patient has no recurrent signs 8 months after surgery

Sertoli Cell Tumor Accompanied by Pancytopenia in a Dog

최을수,김현욱,최지혜,김혜진,장재영,이창우 한국임상수의학회 2008 한국임상수의학회지 Vol.25 No.6

11 year old male Yorkshire terrier was referred to Haemaru Referral Animal Hospital with signs of hematuria, petechia, and gynecomastia. Blood works revealed severe leukopenia, moderate anemia and severe thrombocytopenia. On ultrasonography and radiography, mixed echo texture mass was found in abdomen. The abdominal mass was surgically removed, and submitted for histopathology. Histopathologic features of the tissues were consistent with malignant Sertoli cell tumor. Bone marrow aspirates were hypocellular. Serum estrogen concentration was 72.80 pg/ ml (normal range for females <15 pg/ml) after surgery. Clinical signs of feminization and hemorrhagic diathesis were attributed to hyperestrinism caused by the tumor. The dog was put on fluid therapy, antibiotics and palliative drugs and survived 2 more weeks after surgery without clinical improvement.

개에서 Norepinephrine 분비 갈색세포종 증례1

최을수,김동훈,김현욱,최지혜,장재영 한국임상수의학회 2009 한국임상수의학회지 Vol.26 No.3

An-11-year-old male Shih-tzu was admitted to emergency care unit of Haemaru Referral Animal Hospital with signs of dyspnea, anuria and depression. There were abnormalities on complete blood count and serum chemistry included leukocytosis with mild left shift, mild azotemia, and increased ALT activity. Fluid therapy (0.9% saline, 40 ml/ hr) and antibiotics were immediately initiated. The patient began to vomit after 5 hours’ rest and pale mucous membrane, bradycardia, and hypertension were noted. Abdominal ultrasonography revealed enlarged left adrenal gland and thrombus in caudal vena cava (CVC). Result of ACTH stimulation test was normal. Cytology of ultrasound-guided FNA smears showed numerous naked nuclei, which was suggestive of adrenal medullar tumor. Concentrations of 24 hour urine metanephrine and normetanephrine was moderately increased compared to those of a control dog. Adrenal mass was surgically removed, and biopsy of the CVC mass was obtained. After surgery the patient began to recover but the dog acutely developed cardiopulmonary arrest and died. On histopathology the adrenal mass and biopsy of the CVC mass were consistent with pheochromocytoma. On electron microscopic view norepinephrine specific granules were found in the cytoplasm of tumor cells.

개 원발성 비강내 전염성 성병성 종양 예

최을수,김민규,윤화영,이창우 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3

A 9-year-old male Maltese with foamy nasal discharge, respiratory distress, and sneezing followed by epistaxis was presented to the Veterinary Medical Teaching Hospital of Seoul National University. Radiography showed no significant findings from an open mouth view. Rhinoscopy also did not find any remarkable lesions in the nasal cavity. But when vigorously swabbing the nasal cavity, numerous cells having round nuclei, coarse reticular chromatin, one large nucleolus and distinct cytoplasmic vacuoles, which is typical for canine transmissible venereal tumor cells were collected. We thoroughly searched for any primary transmissible venereal tumor at the other areas of the body other than the nasal cavity, but found none. The patient responded well to vincristine, and the clinical signs resolved with no respiratory distress, sneezing or epistaxis.

Tumoral calcinosis의 증례 Ⅰ

최을수 로얄에이알씨 주식회사 2003 로얄동물임상의학 Vol.- No.-

도베르만 핀셔 견의 호산성 절종증

최을수 로얄에이알씨 주식회사 2003 로얄동물임상의학 Vol.- No.-

A case of uterine adenocarcinoma in a spayed female dog

최을수 한국임상수의학회 2013 한국임상수의학회지 Vol.30 No.1

A 10-year-old spayed female Pekinese dog was referred to veterinary medical teaching hospital of Chonbuk National University with signs of dysuria, abdominal distension, and hematuria. Abdominal radiography revealed a large oval soft tissue mass in cranial abdomen, which was a fluid filled cyst containing a round mass by ultrasonography. Exploratory laparatomy found a 4 cm cyst containing reddish brown fluid and a 1.5 cm small round mass attached to the wall. Cytological impression of the imprint smears of the resected mass were highly malignant adenocarcinoma,which was confirmed by histopathology of the mass and the cyst. After the surgery the patient recovered uneventfully and discharged. The tumor recurred about one year after surgery, and second surgery performed at the owner’s request. However the tumor recurred in two months with metastatic disease in the lung and the dog survived three more months after surgery.

A suspected case of Lyme borreliosis in a hunting dog in Korea

최을수,Hyun Wook Kim,Sung Eun You,Hee Jeong Youn 대한수의학회 2009 Journal of Veterinary Science Vol.10 No.1

A two-year-old male Pointer had been presented with anorexia, cachexia, and weight loss of 10-day duration. Upon physical examination, fever, lethargy, superficial lymph node enlargement, and tick infestation were noted. The only abnormality in CBC and serum chemistry analyses was mild hyperglobulinemia. Spleen was enlarged by radiography, and the lymph nodes showed neutrophilic lymphadenitis by cytological examination. A polymerase chain reaction test for babesiosis and commercial ELISA tests for Ehrlichia canis, heartworm, and Lyme disease was negative except for Lyme disease, which was verified by both an IFA-IgG test and a quantitative C6 assay. Doxycycline was administered for 2 weeks and the recovery was uneventful. Post-treatment C6 titer decreased to within normal limits.

규산코팅 벼 종자를 이용한 담수직파재배 시 벼 키다리병 경감효과

강양순,김완중,김연주,정기홍,최을수 한국작물학회 2016 한국작물학회지 Vol.61 No.1

To investigate the effect of soluble silicate zeolite dressing of the rice against bakanae disease, field trial in reclaimed land and in vitro were carried out. The coated rice seeds (SCS) which were dressed with the mixture of 25% silicic acids (binder), and the zeolite (coating powder). In wet direct seeding, uniform scattering of rice seeds on the soil surface and the better seedling establishment were shown in SCS treatment plots. The incidence of bakanae disease began from the mid tillering stage toward the heading stage. Around heading stage, the ratio of infected tillers reached its highest point by 9.9% in non-SCS treatment plots. While, in SCS treatment plots, the ratio of infected tillers was no more than 0.01%. The vitality of the pathogenic fungi of bakanae disease in the SCS and non-SCS samples were assessed. Samples were incubated for one week keeping proper humidity at 30°C after inoculated with panicles of infected rice plants from experimental field plots. In non-SCS treatment, pinkish colonies were formed on the grain surface of panicle of infected plants, and mycelium, macro-conidia and micro-conidia were developed actively inside part of infected grain inoculated. While in SCS treatment, micro-conidia and mycelium were not survived and the growth of macro-conidia, mycelia were greatly inhibited and withered. Based on the results, it is concluded that the environmental friendly control of bakanae disease by use of SCS is possible and soluble silicate can be applied as agents for replacement of seed disinfection.