http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Metabolic Super Scan in 18F-FDG PET/CT Imaging
김대응,김창근,박순아,정상아,양세훈 대한의학회 2010 Journal of Korean medical science Vol.25 No.8
A 50-yr-old man presented with intermittent hemoptysis and was diagnosed small cell lung cancer. 18F-FDG PET/CT for staging demonstrated extensive hypermetabolic lesions throughout the skeleton and liver. Interestingly, skeletal muscles of limbs, mediastinum,bowel, and especially brain showed very low FDG uptake. Because of some characteristics in common with super scan on skeletal scintigraphy, this case could be considered as ‘metabolic super scan’.
김대응,박순아,김창근 대한의학회 2011 Journal of Korean medical science Vol.26 No.7
The purpose of this study was to evaluate the value of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) for detecting the recurrence of gastric cancer. We performed a retrospective review of 139 consecutive patients who underwent PET/CT and contrast-enhanced abdominal CT (CECT) for surveillance of gastric cancer after curative resection. Recurrence of gastric cancer was validated by histopathologic examination for local recurrence or serial imaging study follow-up with at least 1 yr interval for recurrence of distant metastasis form. Twenty-eight patients (20.1%)were confirmed as recurrence. On the patient based analysis, there was no statistically significant difference in the sensitivity, specificity and accuracy of PET/CT (53.6%, 84.7%,and 78.4%, respectively) and those of CECT (64.3%, 86.5%, and 82.0%, respectively) for detecting tumor recurrence except in detection of peritoneal carcinomatosis. Among 36recurrent lesions, 8 lesions (22.2%) were detected only on PET/CT, and 10 lesions (27.8%)only on CECT. PET/CT had detected secondary malignancy in 8 patients. PET/CT is as accurate as CECT in detection of gastric cancer recurrence after curative resection,excepting detection of peritoneal carcinomatosis. Moreover, additional PET/CT on CECT could improve detection rate of tumor recurrence and provide other critical information such as unexpected secondary malignancy.
김대응,정환정,이창문,김남호,이삼윤,이문영,최을식,박순아,김창근,황효숙,임석태,손명희 한국고분자학회 2014 Macromolecular Research Vol.22 No.3
Vascular endothelial growth factor (VEGF) plays a pivotal role in angiogenesis in an infarcted myocardium. The purpose of the current investigation was to validate whether a radiolabeled VEGF delivery system can beeffectively monitored in vivo, and to ascertain whether the growth factor induces an angiogenic effect to facilitaterecovery from infarct conditions in rodent myocardial infarction (MI) models. Rat MI models were divided intothree groups, one with left anterior descending coronary artery (LAD) ligation with no injection (the control group),one with LAD ligation and I-131 VEGF injection (the VEGF group), and one with LAD ligation and I-131 VEGF-loadedchitosan injection (the VIC group). On day 7 after injection, autoradiography imaging was performed, followed by semiquantitativeand histopathologic analyses. In semi-quantitative analysis, the mean anterior-to-inferior wall ratio of the VICgroup was significantly higher than those of the control and VEGF groups (p<0.05). Histopathologic experimentsrevealed a marked increase in microvascular density in the VIC group compared to those of the control and VEGF groups(p<0.05). Intramyocardially injected VIC was not only effectively monitored in vivo, but also stimulated therapeuticangiogenesis in the infarcted myocardium. Our findings support that the developed VIC is a novel theranostic toolto improve myocardial perfusion following myocardial infarction.
가상 프로토타이핑 개발도구 기반의 교차개발환경 설계 및 구현
김대응(Dae-Eung Kim),이정배(Jeong-Bae Lee),임기욱(Kee-Wook Rim),황영섭(Young-Sup Hwang),안성순(Sung-Soon Ahn) 한국콘텐츠학회 2009 한국콘텐츠학회논문지 Vol.9 No.5
최근 임베디드 시스템 개발시간을 단축시키고 고객들의 요구사항을 충족시키기 위하여 많은 방법론과 개발환경 방법들이 제시되고 있다. 특히. 본 논문에서는 임베디드 시스템 개발 시 사용되는 교차개발환경을 개선하여 개발시간을 단축시키는 방법을 제안하였다. 이러한 방법은 가상 프로토타이핑 개발도구와 임베디드 시스템 개발 보드를 이용하여 개발환경을 하는 경우에 제한적으로 적용된다. 구현 및 실험결과 분석을 통하여 한 번 이상의 수정이 요구되는 교차개발환경에서는 기존 개발 방법보다 본 논문에서 제시한 방법이 우수함을 증명하였다. Recently, many methodologies and development environment to shorten embedded system development time and to satisfy customer requirement were proposed. In this paper, a method to shorten development time by improving cross development environment is proposed for embedded system development, This method was designed and implemented just for the environment using virtual prototyping development tools and embedded development kit. According to implementation and result analysis, the proposed method show the better performance the than existing method in the cross development environment which is required to modify more than once.
김대응 ( Dae-eung Kim ),이정배 ( Jeong-bae Lee ),임기욱 ( Keewook Rim ),황영섭 ( Youngsup Hwang ),남지은 ( Ji-yeun Nam ),안성순 ( Sungsoon Ahn ),탁영진 ( Youngjin Tak ),엄태정 ( Tae-jung Eom ) 한국정보처리학회 2009 한국정보처리학회 학술대회논문집 Vol.16 No.1
기존 통합 프로토타이핑 시스템은 가상과 실물 프로토타이핑간의 단순 연결을 통하여 시뮬레이션만하는 것이 한계였다. 본 논문에서는 그러한 통합 프로토타이핑 기술을 개량하여 GUI기반의 가상 프로토타이핑 개발도구에 컴포넌트형태로 넣어서 드래그엔드랍을 통한 통합 프로토타이핑 시스템 환경을 구축하는 것에 대해서 보이고 있다.