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제갈준,최을수,이창우 한국임상수의학회 2005 한국임상수의학회지 Vol.22 No.1
A 4 year-old Doberman Pinscher was presented with periocular skin lesions which has developed after climbing a mountain with the client. Cytologic preparations of the periocular skin lesions revealed marked eosinophilic infiltration, and a few neutrophils, lymphocytes and epithelial cells. These findings are consistent with eosinophilic furunculosis of the face typically in medium breed dogs. The patient was administered orally with prednisolone 1mg/kg for 2 weeks. The skin lesions were regressed responsively. The patient has no recurrent signs.
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최을수,제갈준,배보경,최지희,정성목,최해경,김대응,이창우 한국임상수의학회 2002 한국임상수의학회지 Vol.19 No.3
A 9-year-old male Yorkshire terrior with recurrent chronic otitis externa and otitis interna was referred to the Veterinary Medical Teaching Hospital of Seoul National University. Radiographic findings indicated mineralization around the right ear canal. A tan nodular mass, 1cm in diameter, was noted near the tympanum after total ear canal ablation. Cytologically, the imprint smear of the cut surface of the mass produced clusters of cells with abundant and weakly basophilic cytoplasm, one small round nucleus and one or two nucleoli, mixed with both degenerate and non degenerate neutrophils. The location of the nuclei was eccentric, and some cells contained somewhat coarse black granules in their cytoplasms, on which the mass was diagnosed as ceruminous gland adenoma or hyperplasia associated with inflammation. Histopathologic examination of the tumor was compatible with a diagnosis of ceruminous gland adenoma. The patient is responding well to sugery and antimicrobial treatment.
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개의 요석증 : 품종, 나이, 성별, 해부학적 위치, 소변 pH, 요결정, 요결석 성분사이의 상호관계 (270 증례)
김채욱,최을수,제갈준,배보경,이두형,고영환,이창우 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.3
A retrospective analysis was performed with 270 cases of canine urolithiasis examined at Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul Nat'l University in the period between January 2001 and December 2003. The Shih-Tzu (64 cases), Yorkshire terrier (60 cases), miniature schnauzer (41 cases) and maltese terrier (36 cases) had higher incidences than other breeds. Canine urolithiasis occurred from 4 months to 15 years of age, but the most prevalent age was 3 years. Mean age was 5.683.14 years. The major mineral component of calculi was struvite (54.1%) and calcium oxalate (30.4%). There was no sex prevalences: male 131 cases, female 132 cases. The most prevalent anatomic locations of calculi were urinary bladder (53 of 131 cases), urethra (24 of 131 cases) and bladder/urethra (45 of 131 cases) in males and urinary bladder (103 of 132 cases) in females. The major mineral component of calculi in urinary bladder was struvite (102 of 160 cases), and that in urethra (13 of 25 cases) and multiple locations (29 of 62 cases) was calcium oxalate. The major components of calculi were not always consistent with the components which could be expected from urine pH and crystals. So it is suggested that the components of the calculi must be analyzed after surgical removal to prevent the recurrence when the calculi could not be dissolved by diets or urine pH modifiers.
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Zearalenone ELISA kits의 응용에 관한 연구
윤화중,김태종,이승윤,제갈준,윤지병,Yoon, Hwa-joong,Kim, Tae-Jong,Lee, Sung-Yun,JeGal, Jun,Yoon, Ji-Byung 대한수의학회 1998 大韓獸醫學會誌 Vol.38 No.2
For the extraction and measurement of zearalenone in the corn, bean, wheat and barley contaminated with Fusarium graminearum, the zearalenone-oxime, zearalenone-oxime BSA and zearalenone monoclonal antibodies were studied to develop and apply the direct competitive enzyme linked immunosorbent assay (ELISA). The extraction range of zearalenone with the monoclonal antibodies produced in this experiment was 10ng to 500ng/g feed and the 50% inhibition value was 50ng/ml. The mean recoveries of zearalenone artificially spiked in the ground corn were 89%. The specificity of F-2 monoclonal antibody for the analogues was favorable for the direct competitive ELISA. The result of the experiment showed the zearalenone in the corn, bean, wheat and barely naturally contaminated with the mold would be suitable for extraction and measurement with the monoclonal antibodies.
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